1. Octahedral molybdenum cluster as a photoactive antimicrobial additive to a fluoroplastic
- Author
-
C. Burton, Olga A. Efremova, Stéphane Cordier, Yann Molard, Yuri A. Vorotnikov, Patricia Zhu, Peter M. Kozhin, Alexander Alekseev, Yuri V. Mironov, Natalia A. Vorotnikova, Mark Bradley, Darya V. Evtushok, Maria Amela-Cortes, Paul D. Topham, Michael A. Shestopalov, Anton I. Smolentsev, Nikolaev Institute of Inorganic Chemistry [Novosibirsk] (NIC), Siberian Branch of the Russian Academy of Sciences (SB RAS), Institut des Sciences Chimiques de Rennes (ISCR), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA), Aston University [Birmingham], University of Edinburgh, EP/R006393/1, Engineering and Physical Sciences Research Council, RSG\R1\180123, Royal Society, 19-53-12019, Российский Фонд Фундаментальных Исследований (РФФИ), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), and Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
Models, Molecular ,Magnetic Resonance Spectroscopy ,Materials science ,Light ,Bleach ,Polymers ,Colony Count, Microbial ,chemistry.chemical_element ,Bioengineering ,02 engineering and technology ,010402 general chemistry ,Photochemistry ,01 natural sciences ,Octahedral tungsten cluster ,Biomaterials ,chemistry.chemical_compound ,Oxygen permeability ,Anti-Infective Agents ,photo-dynamic inactivation ,[CHIM]Chemical Sciences ,Molybdenum ,anti-bacterial materials ,chemistry.chemical_classification ,Reactive oxygen species ,Bacteria ,Octahedral molybdenum cluster ,Singlet oxygen ,Fluorine ,021001 nanoscience & nanotechnology ,0104 chemical sciences ,Spectrometry, Fluorescence ,Membrane ,chemistry ,Mechanics of Materials ,Fluoropolymer ,0210 nano-technology ,Antibacterial activity - Abstract
International audience; Finding methods that fight bacterial infection or contamination, while minimising our reliance on antibiotics is one of the most pressing needs of this century. Although the utilisation of UV-C light and strong oxidising agents, such as bleach, are still efficacious methods for eliminating bacterial surface contamination, both methods present severe health and/or environmental hazards. Materials with intrinsic photodynamic activity (i.e. a material's ability upon photoexcitation to convert molecular oxygen into reactive oxygen species such as singlet oxygen), which work with light within the visible photomagnetic spectrum could offer a significantly safer alternative. Here we present a new, bespoke molybdenum cluster (BuN)[{MoI}(CF(CF)COO)], which is both efficient in the generation of singlet oxygen upon photoirradiation and compatible with the fluoropolymer (F-32L) known for its good oxygen permeability. Thus, (BuN)[{MoI(CF(CF)COO)]/F-32L mixtures have been solution-processed to give homogenous films of smooth and fibrous morphologies and which displayed high photoinduced antibacterial activity against four common pathogens under visible light irradiation. These materials thus have potential in applications ranging from antibacterial coatings to filtration membranes and air conditioners to prevent spread of bacterial infections.
- Published
- 2019
- Full Text
- View/download PDF