1. Symmetric ambulatory arterial stiffness index in the young
- Author
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Joseph Mahgerefteh, Fredrick J. Kaskel, Minh B. Nguyen, and Pamela Singer
- Subjects
Adult ,Male ,Pediatric Obesity ,medicine.medical_specialty ,Ambulatory blood pressure ,Adolescent ,Diastole ,Blood Pressure ,030204 cardiovascular system & hematology ,Prehypertension ,Young Adult ,03 medical and health sciences ,Vascular Stiffness ,0302 clinical medicine ,Risk Factors ,Internal medicine ,Internal Medicine ,medicine ,Humans ,030212 general & internal medicine ,Child ,Retrospective Studies ,Anthropometry ,business.industry ,Pediatric hypertension ,Arteries ,Blood Pressure Monitoring, Ambulatory ,medicine.disease ,Surgery ,Blood pressure ,Hypertension ,Ambulatory ,Arterial stiffness ,Cardiology ,Female ,Cardiology and Cardiovascular Medicine ,business ,White Coat Hypertension - Abstract
The ambulatory arterial stiffness index (AASI) and the symmetric ambulatory arterial stiffness index (s-AASI) have been shown to correlate to arterial stiffness in adults. This study assesses these indices with anthropometric and blood pressure (BP) measures in children. A total of 102 children at a pediatric hypertension clinic who had ambulatory blood pressure monitoring (ABPM) done from 2009 to 2013 were included (75% males, 7-22yo, 47% hypertensive, 24% prehypertensive, and 34% white-coat hypertensives). AASI is 1 minus the regression slope of diastolic BP values on systolic BP values from a 24-hour ambulatory blood pressure monitoring. s-AASI is the symmetric regression of AASI. Obese patients had a significantly higher AASI. s-AASI correlated with systolic BP variability. In multivariable regression, BP variability independently correlated with AASI and s-AASI. s-AASI is related to systolic dipping.AASI and s-AASI are highly dependent on BP variability in children. Further studies are necessary to assess their utility.
- Published
- 2016
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