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Your search keyword '"Palumbo, Giovanna"' showing total 6 results
Start Over Author "Palumbo, Giovanna" Publisher elsevier bv
6 results on '"Palumbo, Giovanna"'

3. Late mortality and causes of death among 5-year survivors of childhood cancer diagnosed in the period 1960–1999 and registered in the Italian Off-Therapy Registry

Author

Bagnasco, Francesca, primary, Caruso, Silvia, additional, Andreano, Anita, additional, Valsecchi, Maria Grazia, additional, Jankovic, Momcilo, additional, Biondi, Andrea, additional, Miligi, Lucia, additional, Casella, Claudia, additional, Terenziani, Monica, additional, Massimino, Maura, additional, Sacerdote, Carlotta, additional, Morsellino, Vera, additional, Erminio, Giovanni, additional, Garaventa, Alberto, additional, Faraci, Maura, additional, Micalizzi, Concetta, additional, Garrè, Maria Luisa, additional, Pillon, Marta, additional, Basso, Giuseppe, additional, Biasin, Eleonora, additional, Fagioli, Franca, additional, Rondelli, Roberto, additional, Pession, Andrea, additional, Locatelli, Franco, additional, Santoro, Nicola, additional, Indolfi, Paolo, additional, Palumbo, Giovanna, additional, Russo, Giovanna, additional, Verzegnassi, Federico, additional, Favre, Claudio, additional, Zecca, Marco, additional, Mura, Rossella, additional, D'Angelo, Paolo, additional, Cano, Carmen, additional, Byrne, Julianne, additional, Haupt, Riccardo, additional, Pierani, Paolo, additional, Pession, Andreea, additional, Porta, Fulvio, additional, Consarino, Caterina, additional, Burnelli, Roberta, additional, Fedeli, Fausto, additional, Cellini, Monica, additional, Casale, Fiorina, additional, Menna, Giuseppe, additional, Bertolini, Patrizia, additional, Caniglia, Maurizio, additional, Cecinati, Valerio, additional, Casazza, Gabriella, additional, Foà, Roberto, additional, Clerico, Anna, additional, Ladogana, Saverio, additional, Galimberti, Daniela, additional, Rabusin, Marco, additional, Nespoli, Luigi, additional, and Cesaro, Simone, additional

Published
2019
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4. Detection of thermal gradients through fiber-optic Chirped Fiber Bragg Grating (CFBG): Medical thermal ablation scenario

Author

Korganbayev, Sanzhar, primary, Orazayev, Yerzhan, additional, Sovetov, Sultan, additional, Bazyl, Ali, additional, Schena, Emiliano, additional, Massaroni, Carlo, additional, Gassino, Riccardo, additional, Vallan, Alberto, additional, Perrone, Guido, additional, Saccomandi, Paola, additional, Arturo Caponero, Michele, additional, Palumbo, Giovanna, additional, Campopiano, Stefania, additional, Iadicicco, Agostino, additional, and Tosi, Daniele, additional

Published
2018
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6. Mucoadhesive PEGylated inulin-based self-assembling nanoparticles: In vitro and ex vivo transcorneal permeation enhancement of corticosteroids

Author

Fabio Salvatore Palumbo, Giovanna Pitarresi, Gaetano Giammona, Mariano Licciardi, Flavia Bongiovì, Giulia Di Prima, and Giulia Di Prima, Flavia Bongiovì, Fabio Salvatore Palumbo, Giovanna Pitarresi, Mariano Licciardi∗, Gaetano Giammona

Subjects
Polyethylene glycol, Inulin, Self-assembling nanoparticles, Transcorneal delivery, Retinoic acid, Polyethylene glycol, Transcorneal delivery, Inulin, Self-assembling nanoparticles, Pharmaceutical Science, Nanoparticle, 02 engineering and technology, Penetration (firestop), Permeation, 021001 nanoscience & nanotechnology, 030226 pharmacology & pharmacy, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, chemistry, Settore CHIM/09 - Farmaceutico Tecnologico Applicativo, Drug delivery, Amphiphile, PEG ratio, Retinoic acid, Mucoadhesion, Biophysics, 0210 nano-technology
Abstract

As transcorneal drug delivery is still a challenge, the scope of the present study was to prepare useful nanosystems able to enhance transcorneal permeation/penetration of drugs. Moreover, this work aims to evaluate the effectiveness of inulin-based nanosystems in the specific field of ocular drug delivery and the effect of PEG chains to promote mucoadhesion, stability and transcorneal penetration/permeation enhancer effect of self-assembling nanoparticles in vitro (transwell systems and HCE) and ex vivo (Franz cells and bovine cornea). In particular, inulin was chosen as the starting natural polysaccharide polymer to design a novel amphiphilic derivative named INU-EDA-RA-PEG capable of self-assembling to form self-assembling nanoparticles and corticosteroids-loaded self-assembling nanoparticles. As observed, self-assembling nanoparticles show appropriate particle size values, mucoadhesivity and cytocompatibility. Moreover, self-assembling nanoparticles are able to act efficiently as permeation/penetration enhancer. Additionally, the presence of PEG has positive influence. Thus, the developed inulin-based nanosystems represent a promising tool to improve transcorneal delivery of corticosteroids.

Published
2019

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