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Start Over Author "Nuray, Uslu" Publisher elsevier bv
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2. Safety of ribavirin in adolescent thalassemic patients with chronic hepatitis C virus infection

Author

Hülya Demir, Gökhan Baysoy, Aysel Yüce, Nuray Uslu, and Inci Nur Saltik Temizel

Subjects
Male, medicine.medical_specialty, Adolescent, Thalassemia, Hepacivirus, Hepatitis C virus, medicine.disease_cause, Antiviral Agents, chemistry.chemical_compound, Flaviviridae, Pegylated interferon, Virology, Internal medicine, Ribavirin, Humans, Medicine, biology, business.industry, virus diseases, Hepatitis C, Hepatitis C, Chronic, medicine.disease, biology.organism_classification, digestive system diseases, Infectious Diseases, chemistry, Ferritins, Immunology, RNA, Viral, Female, business, Viral load, medicine.drug
Abstract

Hepatitis C virus (HCV) infection is still a common and imporant problem in thalassemic patients.1 There have been important mprovements in the treatment of chronic HCV infection especially n the last decade. Combination of pegylated interferon (peg-IFN) lfa-2 and ribavirin seems to improve the success of treatment esponse and currently is the recommended therapy for adults.2,3 owever, studies about the treatment of adolescents with thaassemia and HCV infection are limited and are concerned with the dverse effects of the treatment.1,4 We herein present two adoescents with -thalassemia major and chronic HCV infection who ere treated with peg-IFN and ribavirin and discuss the safety of he treatment.

Published
2010
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