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High-quality three-dimensional (3D) seismic reflection and borehole data are used to characterize in detail the structural style and evolution of inversion structures in Horus oil field. This field lies in the central part of Alamein Basin, northern Western Desert of Egypt, in the hanging-wall of a major Jurassic-Early Cretaceous normal fault. This fault delineates the northwestern margin of the basin and extends in an ENE-WSW direction, bounding a half-graben trough in its hanging-wall. This trough had continued subsidence during Early Cretaceous time with depositional thickening of the Lower Cretaceous Alam el Bueib Formation. Fault displacement had ceased near the top of Barremian level. Aptian-Lower Senonian seismically traced levels show a major NE-plunging asymmetrical anticline overlying the Jurassic-Barremian half-graben. This anticline is sub-parallel to the inherited Jurassic rifting fault. At shallower Cretaceous levels, this fault is replaced by a set of WNW-ESE-trending en echelon faults of considerable displacements, which probably indicates a strike-slip component of deformation. These faults display normal separation on all displaced stratigraphic levels and tip upwards in the upper part of the Upper Cretaceous succession. This marks a considerable change in the tectonic mode of the area. NW-SE extensional faults were developed perpendicular to the fold axis, dissecting the anticline into several blocks entrapping hydrocarbons. Detailed seismic structural analysis of growth strata indicates that the fold initiated in Early Senonian time was associated with the inversion of the earlier Jurassic-Barremian half-graben. This basin inversion is attributed to the Syrian-Arc event that dominated North Africa during the Late Cretaceous time and continued through to the Early Miocene. Low fold amplitude coupled with normal displacements on the deep-seated ENE-WSW-trending Jurassic-Barremian fault indicate a mild phase of positive inversion. The Upper Senonian-Eocene stratigraphic sequences increased in thickness in the back-troughs that were associated with basin inversion.