Search

Your search keyword '"María Valle"' showing total 15 results
Start Over Author "María Valle" Publisher elsevier bv
15 results on '"María Valle"'

2. Sobresedación Zero como herramienta de confort, seguridad y gestión en la unidades de cuidados intensivos

Author

J. Caballero, M. García-Sánchez, E. Palencia-Herrejón, T. Muñoz-Martínez, J.M. Gómez-García, I. Ceniceros-Rozalén, Roser Anglés Coll, José Antonio Acosta Escribano, Miguel Ángel Alcalá Llorente, Rafael Barrientos Vega, Ana Bejar Delgado, Antonio Luis Blesa Malpica, Alfonso Bonet Saris, David Cabestrero Alonso, Mª Isabel Ceniceros Rozalén, Carlos Chamorro Jambrina, Isabel Cherta Vivien, Frutos del Nogal Sáez, José Luis Escalante Cobo, Claudio García Alfaro, Francisco Javier Gil Sánchez, Carolina Giménez-Esparza Vich, Víctor González Sanz, Paloma González Arenas, Teodoro Grau Carmona, José Eugenio Guerrero Sanz, Jorge Ibáñez Juvé, Antonio Jareño Chaumel, Manuel Jiménez Lendínez, María José Jiménez Martín, Antonio Lesmes Serrano, José Ángel Lorente Balanza, José Luis Martínez Melgar, Juan Carlos Montejo González, Tomás Muñoz Martínez, Eduardo Palencia Herrejón, Mercedes Palomar Martínez, Cándido Pardo Rey, Hipólito Pérez Moltó, Ferran Roche Campo, Miguel Ángel Romera Ortega, Rafael Ruiz de Luna González, José Ángel Sánchez-Izquierdo Riera, Alberto Sandiumenge Camps, José Alberto Silva Obregón, Herminia Torrado Santos, Pedro Galdos Anuncibay, Ana María Del Saz Ortiz, Jesús Caballero López, Manuela García Sánchez, Mª Belén Estébanez Montiel, Inmaculada Alcalde Mayayo, Luis Yuste Domínguez, José Manuel Gómez García, Susana Temprano Vázquez, Aaron Blandino Ortiz, María Antonia Estecha Foncea, Lucía López Amor, Itziar Hurlé Peláez, Amélie Marie Solange Le Gall, Mariana Isabel Jorge De Almeida e Silva, Elena Bisbal Andrés, Lourdes Fisac Cuadrado, Cristina Ferri Riera, Lorenzo López Pérez, Gabriel Jesús Moreno González, Vanesa Arauzo Rojo, Elena Ruiz-Escribano Taravilla, Chiara Raffaella Caciano Reátegui, Miguel Ángel González Gallego, Sara Rossich Andreu, Ana María Navas Pérez, Federico Minaya González, Miguel Ángel Rodríguez Yago, María Barber Ansón, Amaia Martiarena Orce, José Lorenzo Labarta Monzón, Rocío Almaraz Velarde, Cristina Muñoz Esteban, Ana Vallejo de la Cueva, Joana Domingo Marco, Tatiana García Rodríguez San Miguel, Sara Alcántara Carmona, Oriol Plans Galván, Juan Diego Jiménez Delgado, Mónica García Simón, Amparo Cabanillas Carrillo, Francisco José Guerrero Gómez, María Riera Sagrera, Laura Bellver Bosch, Helena Dominguez Aguado, Dacil María Parrilla Toribio, Alejandra Virgós Pedreira, David Mosquera Rodríguez, Manuela Fernández Arroyo, Susana González Prado, Laura Sayagués Moreira, Luis Alfonso Marcos Prieto, Jesús Priego Sanz, Aída Fernández Ferreira, Mercedes Ibarz Villamayor, Marcela Patricia Hómez Guzman, Ana Abella Álvarez, Federico Gordo Vidal, Vanessa Blazquez Alcaide, Carolina Fuertes Schott, María Aranda Pérez, Gloria María Valle Fernández, Lorena Zoila Peiró Ferrando, Francisca Inmaculada Pino Sánchez, Sulamita Carvalho Brugger, Africa Carmen Lores Obradors, and Inmaculada de Dios Chacón

Subjects
business.industry, Zero (complex analysis), MEDLINE, 030208 emergency & critical care medicine, Critical Care and Intensive Care Medicine, medicine.disease, Intensive care unit, law.invention, 03 medical and health sciences, 0302 clinical medicine, 030228 respiratory system, law, Medicine, Medical emergency, business
Published
2020

3. Oversedation Zero as a tool for comfort, safety and management in the intensive care unit

Author

José Antonio Acosta Escribano, María Barber Ansón, I. Ceniceros-Rozalén, José Alberto Silva Obregón, Oriol Plans Galván, Francisco José Guerrero Gómez, Víctor González Sanz, Rafael Ruiz de Luna González, José Lorenzo Labarta Monzón, Lorenzo López Pérez, Ana María Navas Pérez, Susana González Prado, Alberto Sandiumenge Camps, Laura Sayagués Moreira, Manuel Jiménez Lendínez, Antonio Lesmes Serrano, Luis Yuste Domínguez, Federico Gordo Vidal, Mariana Isabel Jorge De Almeida e Silva, Lucía López Amor, Mª Isabel Ceniceros Rozalén, María José Jiménez Martín, Federico Minaya González, Mercedes Ibarz Villamayor, Lourdes Fisac Cuadrado, Jesús Caballero López, Helena Dominguez Aguado, Cristina Esteban, M. García-Sánchez, Juan Diego Jiménez Delgado, Inmaculada de Dios Chacón, Miguel Ángel Rodríguez Yago, J.M. Gómez-García, José Manuel Gómez García, Sara Alcántara Carmona, Cristina Ferri Riera, Lorena Zoila Peiró Ferrando, Ana María Del Saz Ortiz, Marcela Patricia Hómez Guzman, Claudio García Alfaro, Teodoro Grau Carmona, Mónica García Simón, Ana Vallejo de la Cueva, David Cabestrero Alonso, Cándido Pardo Rey, Antonio Luis Blesa Malpica, Sulamita Carvalho Brugger, E Palencia-Herrejón, Amparo Cabanillas Carrillo, María Antonia Estecha Foncea, Inmaculada Alcalde Mayayo, Vanessa Blazquez Alcaide, José Eugenio Guerrero Sanz, Manuela García Sánchez, Ana Bejar Delgado, Ana Abella Álvarez, Miguel Ángel González Gallego, Africa Carmen Lores Obradors, Miguel Ángel Alcalá Llorente, Miguel Ángel Romera Ortega, Antonio Jareño Chaumel, Chiara Raffaella Caciano Reátegui, María Riera Sagrera, Gabriel Jesús Moreno González, Mª Belén Estébanez Montiel, Semicyuc, Julio Caballero, Hipólito Pérez Moltó, Rocío Almaraz Velarde, Carolina Giménez-Esparza Vich, Joana Domingo Marco, Vanesa Arauzo Rojo, Amélie Marie Solange Le Gall, Sara Rossich Andreu, Eduardo Palencia Herrejón, Francisca Pino Sánchez, Aída Fernández Ferreira, Frutos del Nogal Sáez, Roser Anglés Coll, Jesús Priego Sanz, Jorge Ibáñez Juvé, Gloria María Valle Fernández, Herminia Torrado Santos, Francisco Javier Gil Sánchez, Luis Alfonso Marcos Prieto, miembros del Gtsad, Tatiana García Rodríguez San Miguel, Rafael Barrientos Vega, Carolina Fuertes Schott, José Luis Martínez Melgar, María Aranda Pérez, Carlos Chamorro Jambrina, Dacil María Parrilla Toribio, Mercedes Palomar Martínez, Elena Ruiz-Escribano Taravilla, Elena Bisbal Andrés, Amaia Martiarena Orce, Isabel Cherta Vivien, Manuela Fernández Arroyo, Alfonso Bonet Saris, Itziar Hurlé Peláez, Tomás Muñoz Martínez, José Ángel Sánchez-Izquierdo Riera, Alejandra Virgós Pedreira, Paloma González Arenas, Ferran Roche Campo, José Ángel Lorente Balanza, Susana Temprano Vázquez, Juan Carlos Montejo González, T. Muñoz-Martínez, David Mosquera Rodríguez, Aaron Blandino Ortiz, Laura Bellver Bosch, José Luis Escalante Cobo, and Pedro Galdos Anuncibay

Subjects
Protocol (science), medicine.medical_specialty, Teamwork, business.industry, Critically ill, media_common.quotation_subject, Sedation, 030208 emergency & critical care medicine, Intensive care unit, law.invention, 03 medical and health sciences, 0302 clinical medicine, Quality of life (healthcare), 030228 respiratory system, Multidisciplinary approach, law, Medicine, Delirium, medicine.symptom, business, Intensive care medicine, media_common
Abstract

Sedation is necessary in the management of critically ill patients, both to alleviate suffering and to cure patients with diseases that require admission to the intensive care unit. Such sedation should be appropriate to the patient needs at each timepoint during clinical evolution, and neither too low (undersedation) nor too high (oversedation). Adequate sedation influences patient comfort, safety, survival, subsequent quality of life, bed rotation of critical care units and costs. Undersedation is detected and quickly corrected. In contrast, oversedation is silent and difficult to prevent in the absence of management guidelines, collective awareness and teamwork. The Zero Oversedation Project of the Sedation, Analgesia and Delirium Working Group of the Spanish Society of Intensive and Critical Care Medicine and Coronary Units aims to offer a practical teaching and collective awareness tool for ensuring patient comfort, safety and management with a view to optimizing the clinical outcomes and minimizing the deleterious effects of excessive sedation. The tool is based on a package of measures that include monitoring pain, analgesia, agitation, sedation, delirium and neuromuscular block, keeping patients pain-free, performing dynamic sedation according to clinical objectives, agreeing upon the multidisciplinary protocol to be followed, and avoiding deep sedation where not clinically indicated.

Published
2020

4. The single nucleotide variant rs2868371 associates with the risk of mortality in non-small cell lung cancer patients: A multicenter prospective validation

Author

María José Ortiz Gordillo, Eleonor Rivin del Campo, Gerardo Sanchez Carmona, Blas David Delgado León, María Valle Enguix-Riego, Jon Cacicedo, Jose María Nieto-Guerrero Gómez, Daniel Herrero Rivera, Marco Perez, Juan Manuel Praena-Fernández, and Jose Luis Lopez Guerra

Subjects
Adult, Male, Oncology, medicine.medical_specialty, Lung Neoplasms, Polymorphism, Single Nucleotide, Glucocorticoid receptor binding, Disease-Free Survival, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, Receptors, Glucocorticoid, 0302 clinical medicine, Glucocorticoid receptor, Carcinoma, Non-Small-Cell Lung, Internal medicine, Genotype, medicine, Humans, SNP, Radiology, Nuclear Medicine and imaging, Prospective Studies, Allele, Promoter Regions, Genetic, Lung cancer, Heat-Shock Proteins, Aged, Proportional Hazards Models, Retrospective Studies, Aged, 80 and over, business.industry, Standard treatment, Hematology, Middle Aged, medicine.disease, Survival Rate, 030220 oncology & carcinogenesis, Female, business, Chromatin immunoprecipitation, Molecular Chaperones
Abstract

Background and purpose Definitive radiation therapy (RT) with or without chemotherapy has become the standard treatment for non-metastatic unresectable non-small cell lung cancer (NSCLC). However, treatment outcomes can differ substantially and patients’ genetic background could play a crucial role. Potential associations between single-nucleotide polymorphisms (SNP) in Heat shock protein beta-1 (HSPB1) and survival have been reported in prior single-institution retrospective reports. Materials and methods The current assay aims to validate such connection in a prospective multicenter study in a European cohort including 181 NSCLC patients. Median follow-up time for all patients was 13 months (range, 3–57 months). Results The results obtained show an association between the rs2868371 GG genotype and better overall survival (HR: 0.35; 95%CI: 0.13–0.96; p = 0.042) in multivariate analysis. Two-year overall survival rate was 72% for patients carrying the rs2868371 GG genotype versus 36% for those patients harboring the rs2868371 CC/CG genotypes (p = 0.013). Additionally, the rs2868371 GG genotype was found to be associated with better disease-free survival in the multivariate analysis (HR: 0.36; 95%CI: 0.13–0.99; p = 0.048). In silico analysis of the potential functional SNP suggested significant difference in the affinity of the Glucocorticoid Receptor binding site between alternative allelic variants, confirmed by chromatin immunoprecipitation analysis displaying stronger affinity for the risk allele (C). Furthermore, our findings indicate that the rs2868371 influences (mRNA) HSPB1 expression, offering insight into the regulation of HSPB1 transcription. Conclusion The functional HSPB1 rs2868371 promoter variant may affect lung cancer survival by regulation of HSPB1 expression levels through glucocorticoid receptor interaction.

Published
2019

5. Sobresedación Zero como herramienta de confort, seguridad y gestión en la unidades de cuidados intensivos

Author

Caballero, J., primary, García-Sánchez, M., additional, Palencia-Herrejón, E., additional, Muñoz-Martínez, T., additional, Gómez-García, J.M., additional, Ceniceros-Rozalén, I., additional, Coll, Roser Anglés, additional, Escribano, José Antonio Acosta, additional, Llorente, Miguel Ángel Alcalá, additional, Vega, Rafael Barrientos, additional, Delgado, Ana Bejar, additional, Malpica, Antonio Luis Blesa, additional, Saris, Alfonso Bonet, additional, Alonso, David Cabestrero, additional, Rozalén, Mª Isabel Ceniceros, additional, Jambrina, Carlos Chamorro, additional, Vivien, Isabel Cherta, additional, Sáez, Frutos del Nogal, additional, Cobo, José Luis Escalante, additional, Alfaro, Claudio García, additional, Sánchez, Francisco Javier Gil, additional, Vich, Carolina Giménez-Esparza, additional, Sanz, Víctor González, additional, Arenas, Paloma González, additional, Carmona, Teodoro Grau, additional, Sanz, José Eugenio Guerrero, additional, Juvé, Jorge Ibáñez, additional, Chaumel, Antonio Jareño, additional, Lendínez, Manuel Jiménez, additional, Martín, María José Jiménez, additional, Serrano, Antonio Lesmes, additional, Balanza, José Ángel Lorente, additional, Melgar, José Luis Martínez, additional, González, Juan Carlos Montejo, additional, Martínez, Tomás Muñoz, additional, Herrejón, Eduardo Palencia, additional, Martínez, Mercedes Palomar, additional, Rey, Cándido Pardo, additional, Moltó, Hipólito Pérez, additional, Campo, Ferran Roche, additional, Ortega, Miguel Ángel Romera, additional, González, Rafael Ruiz de Luna, additional, Riera, José Ángel Sánchez-Izquierdo, additional, Camps, Alberto Sandiumenge, additional, Obregón, José Alberto Silva, additional, Santos, Herminia Torrado, additional, Anuncibay, Pedro Galdos, additional, Ortiz, Ana María Del Saz, additional, López, Jesús Caballero, additional, Sánchez, Manuela García, additional, Montiel, Mª Belén Estébanez, additional, Mayayo, Inmaculada Alcalde, additional, Domínguez, Luis Yuste, additional, García, José Manuel Gómez, additional, Vázquez, Susana Temprano, additional, Ortiz, Aaron Blandino, additional, Foncea, María Antonia Estecha, additional, Amor, Lucía López, additional, Peláez, Itziar Hurlé, additional, Gall, Amélie Marie Solange Le, additional, Silva, Mariana Isabel Jorge De Almeida e, additional, Andrés, Elena Bisbal, additional, Cuadrado, Lourdes Fisac, additional, Riera, Cristina Ferri, additional, Pérez, Lorenzo López, additional, González, Gabriel Jesús Moreno, additional, Rojo, Vanesa Arauzo, additional, Taravilla, Elena Ruiz-Escribano, additional, Reátegui, Chiara Raffaella Caciano, additional, Gallego, Miguel Ángel González, additional, Andreu, Sara Rossich, additional, Pérez, Ana María Navas, additional, González, Federico Minaya, additional, Yago, Miguel Ángel Rodríguez, additional, Ansón, María Barber, additional, Orce, Amaia Martiarena, additional, Monzón, José Lorenzo Labarta, additional, Velarde, Rocío Almaraz, additional, Esteban, Cristina Muñoz, additional, Cueva, Ana Vallejo de la, additional, Marco, Joana Domingo, additional, Miguel, Tatiana García Rodríguez San, additional, Carmona, Sara Alcántara, additional, Galván, Oriol Plans, additional, Delgado, Juan Diego Jiménez, additional, Simón, Mónica García, additional, Carrillo, Amparo Cabanillas, additional, Gómez, Francisco José Guerrero, additional, Sagrera, María Riera, additional, Bosch, Laura Bellver, additional, Aguado, Helena Dominguez, additional, Toribio, Dacil María Parrilla, additional, Pedreira, Alejandra Virgós, additional, Rodríguez, David Mosquera, additional, Arroyo, Manuela Fernández, additional, Prado, Susana González, additional, Moreira, Laura Sayagués, additional, Prieto, Luis Alfonso Marcos, additional, Sanz, Jesús Priego, additional, Ferreira, Aída Fernández, additional, Villamayor, Mercedes Ibarz, additional, Guzman, Marcela Patricia Hómez, additional, Álvarez, Ana Abella, additional, Vidal, Federico Gordo, additional, Alcaide, Vanessa Blazquez, additional, Schott, Carolina Fuertes, additional, Pérez, María Aranda, additional, Fernández, Gloria María Valle, additional, Ferrando, Lorena Zoila Peiró, additional, Sánchez, Francisca Inmaculada Pino, additional, Brugger, Sulamita Carvalho, additional, Obradors, Africa Carmen Lores, additional, and Chacón, Inmaculada de Dios, additional

Published
2020
Full Text
View/download PDF

6. Oversedation Zero as a tool for comfort, safety and management in the intensive care unit

Author

Caballero, J., primary, García-Sánchez, M., additional, Palencia-Herrejón, E., additional, Muñoz-Martínez, T., additional, Gómez-García, J.M., additional, Ceniceros-Rozalén, I., additional, Coll, Roser Anglés, additional, Escribano, José Antonio Acosta, additional, Llorente, Miguel Ángel Alcalá, additional, Vega, Rafael Barrientos, additional, Delgado, Ana Bejar, additional, Malpica, Antonio Luis Blesa, additional, Saris, Alfonso Bonet, additional, Alonso, David Cabestrero, additional, Rozalén, Mª Isabel Ceniceros, additional, Jambrina, Carlos Chamorro, additional, Vivien, Isabel Cherta, additional, Sáez, Frutos del Nogal, additional, Cobo, José Luis Escalante, additional, Alfaro, Claudio García, additional, Sánchez, Francisco Javier Gil, additional, Vich, Carolina Giménez-Esparza, additional, Sanz, Víctor González, additional, Arenas, Paloma González, additional, Carmona, Teodoro Grau, additional, Sanz, José Eugenio Guerrero, additional, Juvé, Jorge Ibáñez, additional, Chaumel, Antonio Jareño, additional, Lendínez, Manuel Jiménez, additional, Martín, María José Jiménez, additional, Serrano, Antonio Lesmes, additional, Balanza, José Ángel Lorente, additional, Melgar, José Luis Martínez, additional, González, Juan Carlos Montejo, additional, Martínez, Tomás Muñoz, additional, Herrejón, Eduardo Palencia, additional, Martínez, Mercedes Palomar, additional, Rey, Cándido Pardo, additional, Moltó, Hipólito Pérez, additional, Campo, Ferran Roche, additional, Ortega, Miguel Ángel Romera, additional, González, Rafael Ruiz de Luna, additional, Riera, José Ángel Sánchez-Izquierdo, additional, Camps, Alberto Sandiumenge, additional, Obregón, José Alberto Silva, additional, Santos, Herminia Torrado, additional, Anuncibay, Pedro Galdos, additional, Ortiz, Ana María Del Saz, additional, López, Jesús Caballero, additional, Sánchez, Manuela García, additional, Montiel, Mª Belén Estébanez, additional, Mayayo, Inmaculada Alcalde, additional, Domínguez, Luis Yuste, additional, García, José Manuel Gómez, additional, Vázquez, Susana Temprano, additional, Ortiz, Aaron Blandino, additional, Foncea, María Antonia Estecha, additional, Amor, Lucía López, additional, Peláez, Itziar Hurlé, additional, Gall, Amélie Marie Solange Le, additional, Silva, Mariana Isabel Jorge De Almeida e, additional, Andrés, Elena Bisbal, additional, Cuadrado, Lourdes Fisac, additional, Riera, Cristina Ferri, additional, Pérez, Lorenzo López, additional, González, Gabriel Jesús Moreno, additional, Rojo, Vanesa Arauzo, additional, Taravilla, Elena Ruiz-Escribano, additional, Reátegui, Chiara Raffaella Caciano, additional, Gallego, Miguel Ángel González, additional, Andreu, Sara Rossich, additional, Pérez, Ana María Navas, additional, González, Federico Minaya, additional, Yago, Miguel Ángel Rodríguez, additional, Ansón, María Barber, additional, Orce, Amaia Martiarena, additional, Monzón, José Lorenzo Labarta, additional, Velarde, Rocío Almaraz, additional, Esteban, Cristina Muñoz, additional, Cueva, Ana Vallejo de la, additional, Marco, Joana Domingo, additional, Miguel, Tatiana García Rodríguez San, additional, Carmona, Sara Alcántara, additional, Galván, Oriol Plans, additional, Delgado, Juan Diego Jiménez, additional, Simón, Mónica García, additional, Carrillo, Amparo Cabanillas, additional, Gómez, Francisco José Guerrero, additional, Sagrera, María Riera, additional, Bosch, Laura Bellver, additional, Aguado, Helena Dominguez, additional, Toribio, Dacil María Parrilla, additional, Pedreira, Alejandra Virgós, additional, Rodríguez, David Mosquera, additional, Arroyo, Manuela Fernández, additional, Prado, Susana González, additional, Moreira, Laura Sayagués, additional, Prieto, Luis Alfonso Marcos, additional, Sanz, Jesús Priego, additional, Ferreira, Aída Fernández, additional, Villamayor, Mercedes Ibarz, additional, Guzman, Marcela Patricia Hómez, additional, Álvarez, Ana Abella, additional, Vidal, Federico Gordo, additional, Alcaide, Vanessa Blazquez, additional, Schott, Carolina Fuertes, additional, Pérez, María Aranda, additional, Fernández, Gloria María Valle, additional, Ferrando, Lorena Zoila Peiró, additional, Sánchez, Francisca Inmaculada Pino, additional, Brugger, Sulamita Carvalho, additional, Obradors, Africa Carmen Lores, additional, and Chacón, Inmaculada de Dios, additional

Published
2020
Full Text
View/download PDF

7. Association of single nucleotide polymorphisms at HSPB1 rs7459185 and TGFB1 rs11466353 with radiation esophagitis in lung cancer

Author

Delgado, Blas David, primary, Enguix-Riego, María Valle, additional, Fernández de Bobadilla, Jon Cacicedo, additional, Herrero Rivera, Daniel, additional, Nieto-Guerrero Gómez, Jose María, additional, Praena-Fernández, Juan Manuel, additional, Rivin del Campo, Eleonor, additional, Ortiz Gordillo, María José, additional, Fernandez Fernandez, María del Carmen, additional, and Lopez Guerra, Jose Luis, additional

Published
2019
Full Text
View/download PDF

9. Inhibitory descending rhombencephalic projections in larval sea lamprey

Author

Silvia María Valle-Maroto, Ramón Anadón, Blanca Fernández-López, Antón Barreiro-Iglesias, M. Celina Rodicio, and Verona Villar-Cerviño

Subjects
Embryo, Nonmammalian, Central nervous system, Inhibitory postsynaptic potential, Efferent Pathways, medicine, Animals, Petromyzon, Spinal cord injury, Neuronal Tract-Tracers, biology, Reticular Formation, General Neuroscience, Lamprey, Neural Inhibition, Anatomy, biology.organism_classification, Spinal cord, medicine.disease, Rhombencephalon, medicine.anatomical_structure, Spinal Cord, nervous system, Larva, Reticular connective tissue, Brainstem, Neuroscience, Nucleus
Abstract

Lampreys are jawless vertebrates, the most basal group of extant vertebrates. This phylogenetic position makes them invaluable models in comparative studies of the vertebrate central nervous system. Lampreys have been used as vertebrate models to study the neuronal circuits underlying locomotion control and axonal regeneration after spinal cord injury. Inhibitory inputs are key elements in the networks controlling locomotor behaviour, but very little is known about the descending inhibitory projections in lampreys. The aim of this study was to investigate the presence of brain-spinal descending inhibitory pathways in larval stages of the sea lamprey Petromyzon marinus by means of tract-tracing with neurobiotin, combined with immunofluorescence triple-labeling methods. Neurobiotin was applied in the rostral spinal cord at the level of the third gill, and inhibitory populations were identified by the use of cocktails of antibodies raised against glycine and GABA. Glycine-immunoreactive (-ir) neurons that project to the spinal cord were observed in three rhombencephalic reticular nuclei: anterior, middle and posterior. Spinal-projecting GABA-ir neurons were observed in the anterior and posterior reticular nuclei. Double glycine-ir/GABA-ir spinal cord-projecting neurons were only observed in the posterior reticular nucleus, and most glycine-ir neurons did not display GABA immunoreactivity. The present results reveal the existence of inhibitory descending projections from brainstem reticular neurons to the spinal cord, which were analyzed in comparative and functional contexts. Further studies should investigate which spinal cord circuits are affected by these descending inhibitory projections.

Published
2011

10. OC-0153: Multicenter prospective validation of HSPB1 rs2868371 SNP and survival in non-small cell lung cancer

Author

D. Herrero Rivera, María Valle Enguix-Riego, J.J. Gordito Soler, J.L. Lopez Guerra, J. Cacicedo Fernández de Bobadilla, M.J. Ortiz Gordillo, J.M. Praena Fernández, Desirée Delgado, and J.M. Nieto-Guerrero Gómez

Subjects
Oncology, medicine.medical_specialty, business.industry, Internal medicine, Medicine, SNP, Radiology, Nuclear Medicine and imaging, Hematology, Non small cell, business, Lung cancer, medicine.disease
Published
2018

11. Análisis de los estilos de vida de la mujer climatérica: un componente esencial en el estudio de las necesidades educativas

Author

Francisca María García Padilla, María Valle López Santos, Teresa Toscano Márquez, and Angela Contreras Martín

Subjects
General Medicine, General Nursing
Abstract

Resumen Objetivo Conocer el comportamiento de los factores conductuales en las usuarias potenciales del programa de Atencion a la mujer climaterica de la Zona Basica de Salud Molino de la Vega, de Huelva. Metodo Estudio descriptivo sobre un total de 70 mujeres (de entre 40 y 60 anos) adscritas a dicha zona. Se aplico un cuestionario de 146 preguntas, agrupadas en 5 dimensiones, previa prueba de jueces y pilotaje. Analisis estadistico: frecuencias absolutas y relativas, aplicacion del test de independencia, analisis de varianza y test de Newman-Keuls. Resultados a) Comportamiento alimentario: el 65% de las encuestadas tomaba leche 2 o mas veces al dia; el 90% mantenia una ingesta moderada de fibra; tomaban carne de ave varias veces a la semana el 83%; cerdo, el 55%; huevos, el 78%; pescado azul, el 75%; hidratos de carbono de absorcion lenta, el 76%. El 86,7% utilizaba el aceite de oliva. b) Actividad fisica: el 40% dijo realizar ejercicio fisico raramente o nunca. c) Conducta respecto al sueno: el 78,3% se despertaba a menudo. d) Conductas psicosociales: el 66% de las mujeres solo salia con su pareja o amistades, de vez en cuando o nunca; en sus relaciones sexuales, el 64,5% no tomaba la iniciativa. e) Otras conductas: el 83,3% no habia fumado nunca, el 18,4% consumia hipnoticos a menudo, el 25% tranquilizantes, y el 48,3% analgesicos. Conclusiones Aunque en todas las dimensiones hay aspectos que deben trabajarse en la intervencion educativa, los comportamientos relacionados con la actividad fisica y los aspectos psicosociales son los puntos donde el repertorio conductual se muestra menos saludable.

Published
2005

12. Involvement of DNMT3B in the pathogenesis of Hirschsprung disease and its possible role as a regulator of neurogenesis in the human enteric nervous system

Author

Torroglosa, Ana, primary, Enguix-Riego, María Valle, additional, Fernández, Raquel María, additional, Román-Rodriguez, Francisco José, additional, Moya-Jiménez, María José, additional, de Agustín, Juan Carlos, additional, Antiñolo, Guillermo, additional, and Borrego, Salud, additional

Published
2014
Full Text
View/download PDF

15. Colangiopancreatografía retrógrada endoscópica en pacientes menores de 18 años: nuestra experiencia

Author

Cerezo-Ruiz, Antonio, primary, Casáis-Juanena, Luis Leonardo, additional, Naranjo-Rodríguez, Antonio, additional, Hervás-Molina, Antonio José, additional, García-Sánchez, María Valle, additional, Reyes-López, Antonio Ángel, additional, González-Galilea, Ángel, additional, Calero-Ayala, Benigno, additional, Sánchez-Ruiz, Francisco, additional, and de Dios-Vega, Juan Francisco, additional

Published
2008
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results