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20 results on '"Mameli, L"'

1. Prophylaxis of HBV-recurrence after liver transplantation in patients with HCC: Risk of HCC recurrence from a large, multicentre retrospective study from Italy

Author

Battistella, S., primary, Zanetto, A., additional, Turco, L., additional, Manuli, C., additional, Pasulo, L., additional, Giannelli, V., additional, Mameli, L., additional, Ferrarese, A., additional, Marenco, S., additional, Ferri, F., additional, Lenci, I., additional, Scandali, G., additional, Biolato, M., additional, Fornasiere, E., additional, Ponziani, F.R., additional, Baroni, G. Svegliati, additional, Giannini, E., additional, Toniutto, P., additional, Lanza, A. Galeota, additional, Rendina, M., additional, Donato, F., additional, Fagiuoli, S., additional, De Maria, N., additional, Morelli, M. Cristina, additional, Martini, Silvia, additional, Trapani, S., additional, Grossi, P., additional, Aghemo, A., additional, Russo, F.P., additional, and Burra, P., additional

Published
2023
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2. Nationwide survey of liver transplantation for Primary Sclerosing Cholangitis in Italy

Author

Morelli, M.C., primary, Gambato, M., additional, Martini, S., additional, Carrai, P., additional, Toniutto, P., additional, Giannelli, V., additional, Donato, F., additional, Lenci, I., additional, Pasulo, L., additional, Mazzarelli, C., additional, Ferrarese, A., additional, Rendina, M., additional, Grieco, A., additional, Lanza, A. Galeota, additional, Svegliati-Baroni, G., additional, De Maria, N., additional, Marenco, S., additional, Mameli, L., additional, and Burra, P., additional

Published
2023
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3. SARS-CoV-2 infection in liver transplantation is associated with favorable outcomes: an Italian transplant registry study

Author

Rendina, M., primary, Barone, M., additional, Trapani, S., additional, Masiero, L., additional, Trerotoli, P., additional, Puoti, F., additional, Lupo, L.G., additional, Agnes, S., additional, Grieco, A., additional, Andorno, E., additional, Marenco, S., additional, Baccarani, U., additional, Toniutto, P., additional, Carraro, A., additional, Colecchia, A., additional, Cescon, M., additional, Morelli, M.C., additional, Cillo, U., additional, Burra, P., additional, Angeli, P., additional, Colledan, M., additional, Fagiuoli, S., additional, De Carlis, L., additional, Belli, L., additional, De Simone, P., additional, Carrai, P., additional, Di Benedetto, F., additional, De Maria, N., additional, Ettorre, G.M., additional, Giannelli, V., additional, Gruttadauria, S., additional, Volpes, R., additional, Mazzaferro, V., additional, Bhoori, S., additional, Romagnoli, R., additional, Martini, S., additional, Rossi, G., additional, Donato, F., additional, Rossi, M., additional, Ginanni Corradini, S., additional, Spada, M., additional, Maggiore, G., additional, Tisone, G., additional, Lenci, I., additional, Vennarecci, G., additional, Di Costanzo, G.G., additional, Vivarelli, M., additional, Svegliati Baroni, G., additional, Zamboni, F. o, additional, Mameli, L., additional, Tafuri, S., additional, Simone, S., additional, Gesualdo, L., additional, Cardillo, M., additional, and Di Leo, A., additional

Published
2022
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4. Pregnancy after liver transplantation: a survey from Italian liver transplants centres

Author

Sciarrone, S.S., primary, Ferrarese, A., additional, Volpato, S., additional, Donato, M.F., additional, Invernizzi, F., additional, Trespidi, L., additional, Ramezzana, I.G., additional, Avolio, A.W., additional, Nure, E., additional, Pascale, M.M., additional, Fagiuoli, S., additional, Pasulo, L., additional, Merli, M., additional, Lapenna, L., additional, Toniutto, P., additional, Lenci, I., additional, Donato, R. Di, additional, De Maria, N., additional, Villa, E., additional, Lanza, A. Galeota, additional, Marenco, S., additional, Bhoori, S., additional, Mameli, L., additional, Cillo, U., additional, Boccagni, P., additional, Russo, F.P., additional, Bo, P., additional, Cosmi, E., additional, and Burra, P., additional

Published
2021
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5. Common issues in the management of patients in the waiting list and after liver transplantation

Author

Burra, P, Belli, L, Ginanni, Corradini, S, Volpes, R, Marzioni, M, Giannini, E, Toniutto, P, Carrai, P, Donato, F, Lanza-Galeota, A, Martini, S, Pasulo, L, Ponziani, F, Russo, F, Coppola, C, Forte, P, Mazzarelli, C, Merli, M, Montalbano, M, Picciotto, F, Rendina, M, Zanetto, A, Angeli, P, Foschi, F, Manini, M, Marzano, A, Perricone, G, Pianta, P, Tamè, M, De Maria, N, Domenicali, M, Ottobrelli, A, Picciotto, A, Ponti, L, Vizzini, G, Corradini, S, Bhoori, S, Ferri, F, Gaffuri, G, Lenci, I, Mameli, L, Morelli, M, and Piras, M. R.

Subjects
medicine.medical_specialty, Alcoholic liver disease, DAAs, HBV recurrence, Immunosuppression, Liver transplantation, Antiviral Agents, Hepatitis C, Chronic, Humans, Italy, Liver Diseases, Alcoholic, Recurrence, Societies, Medical, Disease Management, Liver Transplantation, Waiting Lists, Hepatology, Gastroenterology, medicine.medical_treatment, 030230 surgery, 03 medical and health sciences, 0302 clinical medicine, Medical, Internal medicine, medicine, In patient, Chronic, Disease management (health), business.industry, Liver Diseases, General surgery, Hcv recurrence, Evidence-based medicine, Alcoholic, medicine.disease, Hepatitis C, surgical procedures, operative, Waiting list, 030211 gastroenterology & hepatology, Societies, business
Abstract

The present document contains the recommendations of an expert panel of transplant hepatologists, appointed by the Italian Association for the Study of the Liver (AISF), on how to manage the most common aspects of liver transplantation: the topics covered include: new treatments for HCV in patients on the waiting list for liver transplantation; antiviral treatments in patients with HCV recurrence after liver transplantation; prophylaxis for HBV recurrence after liver transplantation; indications for liver transplantation in alcoholic liver disease; and Immunosuppressive therapy. The statements on each topic were approved by participants at the AISF Transplant Hepatologist Expert Meeting (organized by the Permanent Committee on Liver Transplantation in Mondello on 4–5 October 2015), and are graded according to the Oxford classification of levels of evidence.

Published
2017
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6. Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial

Author

Davidson, Aj, Frawley, G, Hardy, P, Arnup, Sj, Schuster, T, Lee, K, Hunt, Rw, Stargatt, R, Sheppard, S, Ormond, Gd, Hartmann, Pl, Takagi, Mj, Malarbi, S, Doyle, M, Ragg, P, Backstrom, M, Costi, D, von Ungern Sternberg, Bs, Wilton, Nc, Knottenbelt, G, Disma, NICOLA MASSIMO, Montobbio, G, Mameli, L, Tuo, P, Girbaldi, G, PINI PRATO, Alessio, Mattioli, Girolamo, Wolfler, A, Izzo, F, Salvo, I, Sonzogni, V, Locatelli, Bg, Khotcholava, M, de Graaff, Jc, van Gool, Jt, Numan, Sc, van Veldhuijzen, D, Kalkman, Cj, van Baar, Al, Steenis, Lj, Hagenaars, Jh, Absalom, Ar, Hoekstra, Fm, Volkers, M, Withington, D, Furue, K, Gaudreault, J, Mccann, Me, Berde, C, Soriano, S, Young, V, Sethna, N, Kovatsis, P, Cravero, J, Bellinger, D, Marmor, J, Lynn, A, Ivanova, I, Hunyady, A, Verma, S, Polaner, D, Thomas, J, Mueller, M, Haret, D, Szmuk, P, Steiner, J, Kravitz, B, Surantham, S, Hays, S, Taenzer, A, Maxwell, L, Williams, Rk, Morton, Ns, Bell, G, Dorris, L, Adey, C, Pownall, J, Bagshaw, O, Chisakuta, A, Eissa, A, Stoddart, P, Davis, A, Myles, P, Withngton, De, Degraaff, Jc, Bellinger, Dc, Wolf, A, Mcintosh, N, Carlin, J, Leslie, K, de Lima, J, Hammer, G, Field, D, Gebski, V, Tibboel, D., Development and Treatment of Psychosocial Problems, and Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE)

Subjects
Male, Pediatrics, Hernia, Research Support, U.S. Gov't, P.H.S, CHILDREN, P.H.S, Bayley Scales of Infant Development, law.invention, Child Development, 0302 clinical medicine, Randomized controlled trial, 030202 anesthesiology, law, Medicine, Anesthesia, General anaesthesia, Non-U.S. Gov't, Child, BIRTH COHORT, Wechsler Preschool and Primary Scale of Intelligence, Research Support, Non-U.S. Gov't, Medicine (all), CHILDHOOD EXPOSURE, Age Factors, Wechsler Scales, Brain, Gestational age, General Medicine, Multicenter Study, Inguinal, Randomized Controlled Trial, Cohort, CLINICAL-RESEARCH, Female, Cohort study, medicine.medical_specialty, Spinal, Gestational Age, Anesthesia, General, Anesthesia, Spinal, Child, Preschool, Double-Blind Method, Hernia, Inguinal, Herniorrhaphy, Humans, Infant, Research Support, ACADEMIC-PERFORMANCE, N.I.H, DEVELOPING BRAIN, 03 medical and health sciences, Research Support, N.I.H., Extramural, EARLY EXPOSURE, 030225 pediatrics, Journal Article, Toddler, General, Preschool, business.industry, Extramural, LEARNING-DISABILITIES, CELL-DEATH, NEUROTOXICITY, U.S. Gov't, business
Abstract

Background Preclinical data suggest that general anaesthetics affect brain development. There is mixed evidence from cohort studies that young children exposed to anaesthesia can have an increased risk of poor neurodevelopmental outcome. We aimed to establish whether general anaesthesia in infancy has any effect on neurodevelopmental outcome. Here we report the secondary outcome of neurodevelopmental outcome at 2 years of age in the General Anaesthesia compared to Spinal anaesthesia (GAS) trial.Methods In this international assessor-masked randomised controlled equivalence trial, we recruited infants younger than 60 weeks postmenstrual age, born at greater than 26 weeks ' gestation, and who had inguinal herniorrhaphy, from 28 hospitals in Australia, Italy, the USA, the UK, Canada, the Netherlands, and New Zealand. Infants were randomly assigned (1:1) to receive either awake-regional anaesthesia or sevoflurane-based general anaesthesia. Web-based randomisation was done in blocks of two or four and stratified by site and gestational age at birth. Infants were excluded if they had existing risk factors for neurological injury. The primary outcome of the trial will be the Wechsler Preschool and Primary Scale of Intelligence Third Edition (WPPSI-III) Full Scale Intelligence Quotient score at age 5 years. The secondary outcome, reported here, is the composite cognitive score of the Bayley Scales of Infant and Toddler Development III, assessed at 2 years. The analysis was as per protocol adjusted for gestational age at birth. A difference in means of five points (1/3 SD) was predefined as the clinical equivalence margin. This trial is registered with ANZCTR, number ACTRN12606000441516 and ClinicalTrials.gov, number NCT00756600.Findings Between Feb 9, 2007, and Jan 31, 2013, 363 infants were randomly assigned to receive awake-regional anaesthesia and 359 to general anaesthesia. Outcome data were available for 238 children in the awake-regional group and 294 in the general anaesthesia group. In the as-per-protocol analysis, the cognitive composite score (mean [SD]) was 98.6 (14.2) in the awake-regional group and 98.2 (14.7) in the general anaesthesia group. There was equivalence in mean between groups (awake-regional minus general anaesthesia 0.169, 95% CI-2.30 to 2.64). The median duration of anaesthesia in the general anaesthesia group was 54 min.Interpretation For this secondary outcome, we found no evidence that just less than 1 h of sevoflurane anaesthesia in infancy increases the risk of adverse neurodevelopmental outcome at 2 years of age compared with awake-regional anaesthesia.Funding Australia National Health and Medical Research Council (NHMRC), Health Technologies Assessment-National Institute for Health Research UK, National Institutes of Health, Food and Drug Administration, Australian and New Zealand College of Anaesthetists, Murdoch Childrens Research Institute, Canadian Institute of Health Research, Canadian Anesthesiologists ' Society, Pfizer Canada, Italian Ministry of Heath, Fonds NutsOhra, and UK Clinical Research Network (UKCRN).

Published
2016
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7. Development of a model based on case-mix analysis to predict 6-month patient survival after liver transplantation: a multicenter Italian study

Author

Avolio, A., primary, Lai, Q., additional, Franco, A., additional, Bianco, G., additional, Calia, R., additional, Spoletini, G., additional, Agnes, S., additional, Grieco, A., additional, Rossi, M., additional, Corradini, S. Ginanni, additional, Vivarelli, M., additional, Benedetti, A., additional, Lupo, L., additional, Rendina, M., additional, Colledan, M., additional, Fagiuoli, S., additional, Cescon, M., additional, Donato, C., additional, Zamboni, F., additional, Mameli, L., additional, De Carlis, L., additional, Belli, L., additional, Rossi, G., additional, Donato, F., additional, Mazzaferro, V., additional, Bhoori, S., additional, Di Benedetto, F., additional, De Maria, N., additional, Santaniello, W., additional, Di Costanzo, G., additional, Gruttadauria, S., additional, Volpes, R., additional, De Simone, P., additional, Carrai, P., additional, Spada, M., additional, Nobile, V., additional, Ettorre, G., additional, Giannelli, V., additional, Tisone, G., additional, Lenci, I., additional, Romagnoli, R., additional, Martini, S., additional, Risaliti, A., additional, Toniutto, P., additional, Tedeschi, U., additional, Carraro, A., additional, Burra, P., additional, and Cillo, U., additional

Published
2019
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9. P0903 : Slow HCV kinetics following sofosbuvir + ribavirin administration in real-life setting of liver transplant recipients with severe recurrent hepatitis C

Author

Cento, V., primary, Donato, M.F., additional, Lenci, I., additional, Rendina, M., additional, Milana, M., additional, Di Maio, V.C., additional, Monico, S., additional, Aragri, M., additional, Alfieri, R., additional, Abedrabbo, A., additional, Sforza, D., additional, Manuelli, M., additional, Mameli, L., additional, Sorbo, M.C., additional, Canu, R., additional, Ponti, M.L., additional, Chialà, C., additional, Malinverno, F., additional, Marenco, S., additional, Milanesi, L., additional, Picciotto, A., additional, Rossi, G., additional, Di Leo, A., additional, Tisone, G., additional, Zamboni, F., additional, Ganga, R., additional, Colombo, M., additional, Perno, C.F., additional, Angelico, M., additional, and Ceccherini-Silberstein, F., additional

Published
2015
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10. Italian survey on HBV and liver transplantation in a cohort of 2260 patients

Author

Fasulo, R., primary, Marzano, A., additional, Caccamo, L., additional, Salizzoni, M., additional, Cocchis, D., additional, Mirabella, S., additional, De Carlis, L., additional, Mangoni, I., additional, Cusumano, C., additional, Boccagni, P., additional, Burra, P., additional, Russo, P., additional, Bortoluzzi, I., additional, Tamè, M., additional, Andreone, P., additional, Vukotic, R., additional, Volpes, R., additional, Fagiuoli, S., additional, Lucà, M.G., additional, Sangiovanni, L., additional, Iemmolo, R.M., additional, Toniutto, P., additional, Lenisa, I., additional, Zamboni, F., additional, Mameli, L., additional, Piras, M.R., additional, Vennarecci, G., additional, Tisone, G., additional, Anselmo, A., additional, Merli, M., additional, Giannelli, V., additional, Bongiovanni, S., additional, Caneschi, F., additional, Caporaso, N., additional, Conoscitore, P., additional, Coppola, C., additional, Forte, P., additional, Francavilla, R., additional, Gaeta, G.B., additional, Lotti Suffredini, A., additional, Mazzola, M., additional, Parrilli, G., additional, Piai, G., additional, Rendina, M., additional, Scarpellini, M., additional, Staiano, L., additional, and Stornaiuolo, G., additional

Published
2014
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11. OC-20 Prophylaxis of hepatitis B after liver transplantation: report of an Italian survey in a cohort of 2260 patients

Author

Fasulo, R., primary, Marzano, A., additional, Salizzoni, M., additional, Cocchis, D., additional, Caccamo, L., additional, Burra, P., additional, Russo, P., additional, Bertoluzzi, I., additional, Fagiuoli, S., additional, Verga, G., additional, Colpani, M., additional, Gaeta, G.B., additional, Stornaiuolo, G., additional, De Carlis, L., additional, Mangoni, I., additional, Zamboni, F., additional, Mameli, L., additional, Piras, M.R., additional, Boccagni, P., additional, Toniutto, P., additional, Lenisa, I., additional, Tamè, M.R., additional, Andreone, P., additional, Vukotic, R., additional, Iemmolo, R.M., additional, Caporaso, N., additional, Parrilli, G., additional, Coppola, C., additional, Masculo, M.C., additional, Conoscitore, P., additional, Volpes, R., additional, Forte, P., additional, Caneschi, F., additional, Vennarecci, G., additional, Tisone, G., additional, Anselmo, A., additional, Merli, M., additional, Giannelli, V., additional, Piai, G., additional, Francavilla, R., additional, and Lotti, A.M., additional

Published
2013
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20. Low dose of aPCC after the initial treatment in acquired haemophilia A is useful to reduce bleeding relapses: Data from the FAIR registry

Author

Cristina Santoro, Luciana Mameli, Sergio Siragusa, Samantha Pasca, Mariasanta Napolitano, Ezio Zanon, Angiola Rocino, Zanon, E., Pasca, S., Siragusa, S., Napolitano, M., Santoro, C., Mameli, L., and Rocino, A.

Subjects
Male, medicine.medical_specialty, Acquired haemophilia, Bleeding relapses, Bypassing agents, Prophylaxis, Aged, Female, Hemophilia A, Hemorrhage, Humans, Prospective Studies, Recombinant Proteins, Recurrence, Retrospective Studies, 030204 cardiovascular system & hematology, Haemophilia, 03 medical and health sciences, 0302 clinical medicine, First line therapy, Internal medicine, medicine, Initial treatment, In patient, Prophylaxi, Activated prothrombin complex concentrate, Bypassing agent, Hematology, business.industry, Low dose, Bleeding relapse, medicine.disease, 030220 oncology & carcinogenesis, business
Abstract

Background: Bypassing agents are the first line therapy in patients with acquired haemophilia A (AHA). Activated prothrombin complex concentrate (aPCC) proved to be effective as initial treatment, but 20% of patients (pts) had relapses. aPCC as short-term prophylaxis to reduce subsequent bleeds is still not clear. Aim: To evaluate whether a short-term prophylaxis with low dose of aPCC can reduce bleeding relapses after initial AHA treatment, maintaining safety. Methods: The FAIR Registry is a retrospective-prospective study started on December 2012, that collected data on all pts with AHA treated with aPCC in 12 Italian Haemophilia Centers. All statistical analyses were carried out in the 56 pts included in the registry. Results: 31 retrospective and 25 prospective pts were evaluated.101 bleeds requiring treatment were reported, 84.1% spontaneous, 71.3% involving muscles or skin. Major bleeds were 38,6%. Low-dose aPCC as short-term prophylaxis was started after the first resolved episode in 15/56 pts, 58% of whom prospective, in a mean dose of 54.2 ± 23.0 IU/kg, higher (61.4 ± 23.4 IU/kg) in the prospective group than in the retrospective one (44.3 ± 19.7 IU/kg) and it was continued up to a mean of 20.5 ± 17.6 days, similar in both groups. A total of 32 bleeding relapses were reported, 87.5% in the retrospective group. Only 9.4% occurred during short-term prophylaxis (p < 0.05). In our Registry no thromboembolic events were found. Conclusion: Initial AHA treatment with aPCC proved to be highly effective, but a consecutive low dose as short-term prophylaxis seems to demonstrate a significant reduction in bleeding relapses maintaining safety.

Published
2019
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