Search

Your search keyword '"Lieubeau, Blandine"' showing total 9 results
Start Over Author "Lieubeau, Blandine" Publisher elsevier bv
9 results on '"Lieubeau, Blandine"'

1. Skeletal Muscle Regenerative Potential of Human MuStem Cells following Transplantation into Injured Mice Muscle

Author

Lorant, Judith, primary, Saury, Charlotte, additional, Schleder, Cindy, additional, Robriquet, Florence, additional, Lieubeau, Blandine, additional, Négroni, Elisa, additional, Leroux, Isabelle, additional, Chabrand, Lucie, additional, Viau, Sabrina, additional, Babarit, Candice, additional, Ledevin, Mireille, additional, Dubreil, Laurence, additional, Hamel, Antoine, additional, Magot, Armelle, additional, Thorin, Chantal, additional, Guevel, Laëtitia, additional, Delorme, Bruno, additional, Péréon, Yann, additional, Butler-Browne, Gillian, additional, Mouly, Vincent, additional, and Rouger, Karl, additional

Published
2018
Full Text
View/download PDF

3. Acute social stress-induced immunomodulation in pigs high and low responders to ACTH

Author

Bacou, Elodie, primary, Haurogné, Karine, additional, Mignot, Grégoire, additional, Allard, Marie, additional, De Beaurepaire, Laurence, additional, Marchand, Jordan, additional, Terenina, Elena, additional, Billon, Yvon, additional, Jacques, Julien, additional, Bach, Jean-Marie, additional, Mormède, Pierre, additional, Hervé, Julie, additional, and Lieubeau, Blandine, additional

Published
2017
Full Text
View/download PDF

5. Systemic Delivery of Allogenic Muscle Stem Cells Induces Long-Term Muscle Repair and Clinical Efficacy in Duchenne Muscular Dystrophy Dogs

Author

Rouger, Karl, primary, Larcher, Thibaut, additional, Dubreil, Laurence, additional, Deschamps, Jack-Yves, additional, Le Guiner, Caroline, additional, Jouvion, Gregory, additional, Delorme, Bruno, additional, Lieubeau, Blandine, additional, Carlus, Marine, additional, Fornasari, Benoît, additional, Theret, Marine, additional, Orlando, Priscilla, additional, Ledevin, Mireille, additional, Zuber, Céline, additional, Leroux, Isabelle, additional, Deleau, Stéphane, additional, Guigand, Lydie, additional, Testault, Isabelle, additional, Le Rumeur, Elisabeth, additional, Fiszman, Marc, additional, and Chérel, Yan, additional

Published
2011
Full Text
View/download PDF

9. β2-adrenoreceptor stimulation dampens the LPS-induced M1 polarization in pig macrophages

Author

Karine Haurogné, Jean-Marie Bach, Marie Allard, Julie Hervé, Grégoire Mignot, Elodie Bacou, Blandine Lieubeau, Immuno-Endocrinologie Cellulaire et Moléculaire (IECM), Ecole Nationale Vétérinaire de Nantes-Université de Nantes (UN)-Institut National de la Recherche Agronomique (INRA), Hervé, Julie, Lieubeau, Blandine, and Institut National de la Recherche Agronomique (INRA)-Université de Nantes (UN)-Ecole Nationale Vétérinaire de Nantes

Subjects
Lipopolysaccharides, 0301 basic medicine, medicine.medical_specialty, Swine, Macrophage, [SDV]Life Sciences [q-bio], Immunology, Adrenoreceptor, beta 2-agonist, Pig, Stimulation, Biology, 03 medical and health sciences, Catecholamines, 0302 clinical medicine, Immune system, Anti-Infective Agents, Internal medicine, medicine, Animals, Secretion, Interleukin 8, Adrenergic beta-2 Receptor Agonists, Innate immune system, Tumor Necrosis Factor-alpha, Macrophages, Interleukin-8, Immunity, Innate, Interleukin-10, Up-Regulation, Interleukin 10, 030104 developmental biology, Endocrinology, Tumor necrosis factor alpha, Receptors, Adrenergic, beta-2, 030217 neurology & neurosurgery, Developmental Biology
Abstract

The cross-talk between sympatho-adreno-medullar axis and innate immunity players was mainly studied in rodents. In intensive husbandry, pigs are exposed to multiple stressors inducing repeated releases of catecholamines that bind to adrenoreceptors (AR) on target cells. Among adrenoreceptors, the (beta 2-AR is largely expressed by immune cells including macrophages. We report herein on the effects of catecholamines, through (beta 2-AR stimulation, on pig macrophage functions activated by LPS. beta 2-AR stimulation of porcine macrophages prevented the LPS-induced increase in TINF alpha and IL-8 secretion while increasing IL-10 secretion. In contrast, treatment with a beta 2-agonist had no effect on anti-microbial functions. Lastly, beta 2-AR stimulation of macrophages reduced the expression of genes up regulated by LPS. Altogether, we demonstrated that (beta 2-AR stimulation of porcine macrophages prevented polarization towards a pro-inflammatory phenotype. Since porcine macrophages are a suitable model for human macrophages, our results might be relevant to appreciate catecholamine effects on human macrophages.

Published
2017

Catalog

Books, media, physical & digital resources
See catalog results