Author: "Libra, A." / Publisher: elsevier bv - Searchworks@Jio Institute Digital Library Search Results

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186 results on '"Libra, A."'

1. Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021

Author: Vollset, SE, Ababneh, HS, Abate, YH, Abbafati, C, Abbasgholizadeh, R, Abbasian, M, Abbastabar, H, Abd Al Magied, AHA, Abd ElHafeez, S, Abdelkader, A, Abdelmasseh, M, Abd-Elsalam, S, Abdi, P, Abdollahi, M, Abdoun, M, Abdullahi, A, Abebe, M, Abiodun, O, Aboagye, RG, Abolhassani, H, Abouzid, M, Aboye, GB, Abreu, LG, Absalan, A, Abualruz, H, Abubakar, B, Abukhadijah, HJJ, Addolorato, G, Adekanmbi, V, Adetunji, CO, Adetunji, JB, Adeyeoluwa, TE, Adha, R, Adhikary, RK, Adnani, QES, Adzigbli, LA, Afrashteh, F, Afzal, MS, Afzal, S, Agbozo, F, Agodi, A, Agrawal, A, Agyemang-Duah, W, Ahinkorah, BO, Ahlstrom, AJ, Ahmad, A, Ahmad, F, Ahmad, MM, Ahmad, S, Ahmed, A, Ahmed, H, Ahmed, S, Ahmed, SA, Akinosoglou, K, Akkaif, MA, Akrami, AE, Akter, E, Al Awaidy, S, Al Hasan, SM, Al Mosa, AS, Al Ta'ani, O, Al Zaabi, OAM, Alahdab, F, Alajlani, MM, Al-Ajlouni, Y, Alalalmeh, SO, Al-Aly, Z, Alam, K, Alam, N, Alam, T, Alam, Z, Al-amer, RM, Alanezi, FM, Alanzi, TM, Albakri, A, Aldhaleei, WA, Aldridge, RW, Alemohammad, SY, Alemu, YM, Al-Gheethi, AAS, Al-Hanawi, MK, Ali, A, Ali, I, Ali, MU, Ali, R, Ali, SSS, Ali, VE, Ali, W, Al-Ibraheem, A, Alicandro, G, Alif, SM, Aljunid, SM, Alla, F, Almazan, JU, Al-Mekhlafi, HM, Alqutaibi, AY, Alrawashdeh, A, Alrousan, SM, Al-Sabah, SK, Alsabri, MA, Altaany, Z, Al-Tammemi, AB, Al-Tawfiq, JA, Altirkawi, KA, Aluh, DO, Alvis-Guzman, N, Al-Wardat, MS, Al-Worafi, YM, Aly, H, Alyahya, MS, Alzoubi, KH, Al-Zyoud, W, Amani, R, Ameyaw, EK, Amin, TT, Amindarolzarbi, A, Amiri, S, Amirzade-Iranaq, MH, Amu, H, Amugsi, DA, Ancuceanu, R, Anderlini, D, Anderson, DB, Andrade, PP, Andrei, CL, Andrei, T, Andrews, EA, Anil, A, Anil, S, Anoushiravani, A, Antony, CM, Antriyandarti, E, Anuoluwa, BS, Anvari, S, Anyasodor, AE, Appiah, F, Aquilano, M, Arab, JP, Arabloo, J, Arafa, EA, Arafat, M, Aravkin, AY, Ardekani, A, Areda, D, Aregawi, BB, Aremu, A, Ariffin, H, Arkew, M, Armani, K, Artamonov, AA, Arumugam, A, Asghari-Jafarabadi, M, Ashbaugh, C, Astell-Burt, T, Athari, SS, Atorkey, P, Atout, MMW, Aujayeb, A, Ausloos, M, Awad, H, Awotidebe, AW, Ayatollahi, H, Ayuso-Mateos, JL, Azadnajafabad, S, Azeez, FK, Azevedo, RMS, Badar, M, Baghdadi, S, Bagheri, M, Bagheri, N, Bai, R, Baker, JL, Bako, AT, Balakrishnan, S, Balcha, WF, Baltatu, OC, Barchitta, M, Bardideh, E, Barker-Collo, SL, Bärnighausen, TW, Barqawi, HJ, Barteit, S, Basiru, A, Basso, JD, Bastan, M-M, Basu, S, Bauckneht, M, Baune, BT, Bayati, M, Bayileyegn, NS, Behnoush, AH, Behzadi, P, Beiranvand, M, Bello, OO, Belo, L, Beloukas, A, Bemanalizadeh, M, Bensenor, IM, Benzian, H, Beran, A, Berezvai, Z, Bernstein, RS, Bettencourt, PJG, Beyene, KA, Beyene, MG, Bhagat, DS, Bhagavathula, AS, Bhala, N, Bhandari, D, Bharadwaj, R, Bhardwaj, N, Bhardwaj, P, Bhargava, A, Bhaskar, S, Bhat, V, Bhattacharjee, NV, Bhatti, GK, Bhatti, JS, Bhatti, MS, Bhuiyan, MA, Bisignano, C, Biswas, B, Bjørge, T, Bodolica, V, Bodunrin, AO, Bonakdar Hashemi, M, Bora Basara, B, Borhany, H, Bosoka, SA, Botero Carvajal, A, Bouaoud, S, Boufous, S, Boxe, C, Boyko, EJ, Brady, OJ, Braithwaite, D, Brauer, M, Brazo-Sayavera, J, Brenner, H, Brown, CS, Browne, AJ, Brugha, T, Bryazka, D, Bulamu, NB, Buonsenso, D, Burkart, K, Burns, RA, Busse, R, Bustanji, Y, Butt, ZA, Caetano dos Santos, FL, Çakmak Barsbay, M, Calina, D, Campos, LA, Cao, S, Capodici, A, Cárdenas, R, Carreras, G, Carugno, A, Carvalho, M, Castaldelli-Maia, JM, Castelpietra, G, Cattaruzza, MS, Caye, A, Cegolon, L, Cembranel, F, Cenko, E, Cerin, E, Chadban, SJ, Chadwick, J, Chakraborty, C, Chakraborty, S, Chalek, J, Chan, JSK, Chandika, RM, Chandy, S, Charan, J, Chaudhary, AA, Chaurasia, A, Chen, A-T, Chen, H, Chen, MX, Chen, S, Cherbuin, N, Chi, G, Chichagi, F, Chimed-Ochir, O, Chimoriya, R, Ching, PR, Chirinos-Caceres, JL, Chitheer, A, Cho, DY, Cho, WCS, Choi, D-W, Chong, B, Chong, CL, Chopra, H, Chu, D-T, Chung, E, Chutiyami, M, Clayton, JT, Cogen, RM, Cohen, AJ, Columbus, A, Comfort, H, Conde, J, Connolly, JT, Cooper, EEK, Cortese, S, Cruz-Martins, N, da Silva, AG, Dadras, O, Dai, X, Dai, Z, Dalton, BE, Damiani, G, Dandona, L, Dandona, R, Das, JK, Das, S, Dash, NR, Davletov, K, De la Hoz, FP, De Leo, D, Debopadhaya, S, Delgado-Enciso, I, Denova-Gutiérrez, E, Dervenis, N, Desai, HD, Devanbu, VGC, Dewan, SMR, Dhama, K, Dhane, AS, Dhingra, S, Dias da Silva, D, Diaz, D, Diaz, LA, Diaz, MJ, Dima, A, Ding, DD, Do, THP, do Prado, CB, Dodangeh, M, Doegah, PT, Dohare, S, Dong, W, D'Oria, M, Doshi, R, Dowou, RK, Dsouza, HL, Dsouza, V, Dube, J, Dumith, SC, Duncan, BB, Duraes, AR, Duraisamy, S, Durojaiye, OC, Dushpanova, A, Dutta, S, Dzianach, PA, Dziedzic, AM, Eboreime, E, Ebrahimi, A, Ebrahimi Kalan, M, Edinur, HA, Efendi, F, Eikemo, TA, Eini, E, Ekundayo, TC, El Arab, RA, El Sayed, I, Elamin, O, Elemam, NM, ElGohary, GMT, Elhadi, M, Elmeligy, OAA, Elmoselhi, AB, Elshaer, M, Elsohaby, I, Eltahir, ME, Emeto, TI, Eshrati, B, Eslami, M, Esmaeili, Z, Fabin, N, Fagbamigbe, AF, Fagbule, OF, Falzone, L, Fareed, M, Farinha, CSES, Faris, MEM, Faro, A, Fasihi, K, Fatehizadeh, A, Fauk, NK, Fazylov, T, Feigin, VL, Fekadu, G, Feng, X, Fereshtehnejad, S-M, Ferrara, P, Ferreira, N, Firew, BS, Fischer, F, Fitriana, I, Flavel, J, Flor, LS, Folayan, MO, Foley, KM, Fonzo, M, Force, LM, Foschi, M, Freitas, A, Fridayani, NKY, Fukutaki, KG, Furtado, JM, Fux, B, Gaal, PA, Gadanya, MA, Gallus, S, Ganesan, B, Ganiyani, MA, Gautam, RK, Gebi, TG, Gebregergis, MW, Gebrehiwot, M, Getacher, L, Getahun, GKA, Gething, PW, Ghadimi, DJ, Ghadirian, F, Ghafarian, S, Ghailan, KY, Ghasemi, M, Ghasempour Dabaghi, G, Ghazy, RM, Ghoba, S, Gholami, E, Gholamrezanezhad, A, Gholizadeh, N, Ghorbani, M, Ghorbani Vajargah, P, Ghotbi, E, Gil, AU, Gill, TK, Girmay, A, Glasbey, JC, Glushkova, EV, Gnedovskaya, EV, Göbölös, L, Goldust, M, Goleij, P, Golinelli, D, Gopalani, SV, Goulart, AC, Gouravani, M, Goyal, A, Grivna, M, Grosso, G, Guarducci, G, Gubari, MIM, Guicciardi, S, Guimarães, RA, Gulati, S, Gulisashvili, D, Gunawardane, DA, Guo, C, Gupta, AK, Gupta, R, Gupta, S, Gupta, VK, Haakenstad, A, Hadi, NR, Haep, N, Hafiz, A, Haghmorad, D, Haile, D, Hajj Ali, A, Haj-Mirzaian, A, Halboub, ES, Haller, S, Halwani, R, Hamagharib Abdullah, K, Hamdy, NM, Hamoudi, R, Hanifi, N, Hankey, GJ, Haq, ZA, Haque, MR, Harapan, H, Hargono, A, Haro, JM, Hasaballah, AI, Hasan, SMM, Hasanian, M, Hasnain, MS, Hassan, A, Haubold, J, Hay, SI, Hebert, JJ, Hegazi, OE, Heidari, M, Hemmati, M, Henson, CA, Herrera-Serna, BY, Herteliu, C, Heydari, M, Hezam, K, Hidayana, I, Hiraike, Y, Hoan, NQ, Holla, R, Hoogar, P, Horita, N, Hossain, MM, Hosseinzadeh, H, Hosseinzadeh, M, Hostiuc, M, Hostiuc, S, Hu, C, Huang, J, Hultström, M, Hundie, TG, Hunt, AJ, Hushmandi, K, Hussain, J, Hussain, MA, Hussein, NR, Huynh, H-H, Hwang, B-F, Ibitoye, SE, Iftikhar, PM, Ikiroma, AI, Ikwegbue, PC, Ilic, IM, Ilic, MD, Immurana, M, Isa, MA, Islam, MR, Islam, SMS, Ismail, F, Ismail, NE, Isola, G, Iwagami, M, Iyamu, IO, Jacob, L, Jacobsen, KH, Jafarinia, M, Jahankhani, K, Jahanmehr, N, Jain, N, Jairoun, AA, Jakhmola Mani, DR, Jamil, S, Jamora, RDG, Jatau, AI, Javadov, S, Javaheri, T, Jayaram, S, Jee, SH, Jeganathan, J, Jiang, H, Jokar, M, Jonas, JB, Joseph, N, Joshua, CE, Jürisson, M, K, V, Kabir, A, Kabir, Z, Kadashetti, V, Kalankesh, LR, Kalra, S, Kamath, A, Kamath, R, Kamireddy, A, Kanaan, M, Kanchan, T, Kanmiki, EW, Kanmodi, KK, Kansal, SK, Karim, A, Karkhah, S, Kashoo, FZ, Kasraei, H, Kassel, MB, Katikireddi, SV, Kauppila, JH, Kaur, H, Kayode, GA, Kazemi, F, Kazemian, S, Kebede, F, Kendal, ES, Kesse-Guyot, E, Khademvatan, S, Khajuria, H, Khalaji, A, Khalid, A, Khalid, N, Khalilian, A, Khamesipour, F, Khan, F, Khan, MJ, Khan, MAB, Khanmohammadi, S, Khatab, K, Khatatbeh, H, Khatatbeh, MM, Khatib, MN, Khayat Kashani, HR, Kheirallah, KA, Khokhar, M, Khormali, M, Khorrami, Z, Khosla, AA, Khosravi, M, Khosrowjerdi, M, Khubchandani, J, Kifle, ZD, Kim, G, Kim, JS, Kim, MS, Kim, YJ, Kimokoti, RW, Kisa, A, Kisa, S, Knibbs, LD, Knudsen, AKS, Kochhar, S, Kolahi, A-A, Kompani, F, Koren, G, Korzh, O, Krishan, K, Krishna, V, Krishnamoorthy, V, Kucuk Bicer, B, Kuddus, MA, Kuddus, M, Kuitunen, I, Kujan, O, Kulimbet, M, Kulkarni, V, Kumar, GA, Kumar, H, Kumar, N, Kumar, R, Kumar, V, Kundu, A, Kusuma, D, Kyei-Arthur, F, Kytö, V, Kyu, HH, La Vecchia, C, Lacey, B, Ladan, MA, Laflamme, L, Lahariya, C, Lai, DTC, Lalloo, R, Lallukka, T, Lám, J, Lan, Q, Lan, T, Landires, I, Lanfranchi, F, Langguth, B, Lansingh, VC, Laplante-Lévesque, A, Larijani, B, Larsson, AO, Lasrado, S, Lauriola, P, Lawlor, HR, Le, H-H, Le, LKD, Le, NHH, Le, TTT, Le, TDT, Leasher, JL, Lee, DW, Lee, M, Lee, PH, Lee, S-W, Lee, SW, Lee, SWH, Lee, YH, Leigh, J, Leong, E, Li, M-C, Libra, M, Ligade, VS, Lim, L-L, Lim, SS, Limenh, LW, Lindholm, D, Lindstedt, PA, Listl, S, Liu, G, Liu, S, Liu, X, Llanaj, E, López-Bueno, R, López-Gil, JF, Loreche, AM, Lotufo, PA, Lozano, R, Lubinda, J, Lucchetti, G, Luo, L, Lusk, JB, Lv, L, M Amin, HI, Ma, ZF, Maass, KL, Machairas, N, Machoy, M, Madureira-Carvalho, ÁM, Magdy Abd El Razek, H, Maghazachi, AA, Mahadeshwara Prasad, DR, Mahalleh, M, Mahasha, PW, Mahmoud, MA, Mahmoudi, E, Mahmoudvand, G, Makama, M, Malakan Rad, E, Malhotra, K, Malik, AA, Malta, DC, Manla, Y, Mansour, A, Mansouri, MH, Mansouri, P, Mansouri, V, Mansourian, M, Mansournia, MA, Marasini, BP, Marateb, HR, Maravilla, JC, Mardi, P, Marjani, A, Markazi Moghadam, H, Marrugo Arnedo, CA, Martinez, G, Martinez-Piedra, R, Martins-Melo, FR, Martorell, M, Marx, W, Marzo, RR, Masoudi, S, Mathangasinghe, Y, Mathioudakis, AG, Mathur, M, Mathur, N, Matozinhos, FP, Mattumpuram, J, Maude, RJ, Maugeri, A, Mayeli, M, Mazidi, M, Mazzotti, A, McGrath, JJ, McKee, M, McKowen, ALW, McPhail, MA, McPhail, SM, Mehmood, A, Mehrabani-Zeinabad, K, Mehravar, S, Mekene Meto, T, Melese, EB, Mendez-Lopez, MAM, Mendoza, W, Menezes, RG, Mensah, GA, Mensah, LG, Mentis, A-FA, Meo, SA, Meretoja, A, Meretoja, TJ, Mersha, AM, Mestrovic, T, Mettananda, KCD, Mettananda, S, Mhlanga, A, Mhlanga, L, Miazgowski, T, Michalek, IM, Micheletti Gomide Nogueira de Sá, AC, Miller, TR, Minh, LHN, Mirahmadi, A, Mirijello, A, Mirrakhimov, EM, Mirzaei, R, Mitchell, PB, Mittal, C, Moberg, ME, Moghadam Fard, A, Mohajelin, S, Mohamadkhani, A, Mohamed, AI, Mohamed, J, Mohamed, MFH, Mohamed, NS, Mohammad, AM, Mohammadi, S, Mohammed, H, Mohammed, M, Mohammed, S, Mokdad, AH, Molokhia, M, Momani, SM, Momtazmanesh, S, Monasta, L, Mondello, S, Moni, MA, Montazeri, F, Moodi Ghalibaf, A, Moradi, M, Moradi, Y, Moraga, P, Morawska, L, Moreira, RS, Morovatdar, N, Morrison, SD, Mosapour, A, Mosser, JF, Mossialos, E, Motappa, R, Mougin, V, Mousavi, P, Mrejen, M, Mubarik, S, Mueller, UO, Mulita, F, Munjal, K, Murillo-Zamora, E, Musallam, KM, Musina, A-M, Mustafa, G, Myung, W, Nafei, A, Nagarajan, AJ, Naghavi, P, Naik, GR, Naik, G, Nainu, F, Najdaghi, S, Nakhostin Ansari, N, Nangia, V, Narasimha Swamy, S, Nargus, S, Narimani Davani, D, Nascimento, BR, Nascimento, GG, Naser, AY, Nashwan, AJ, Natto, ZS, Nauman, J, Navaratna, SNK, Naveed, M, Nawsherwan, Nayak, BP, Nayak, VC, Negash, H, Negoi, I, Negoi, RI, Nejadghaderi, SA, Nejjari, C, Nematollahi, S, Netsere, HB, Ng, M, Nguefack-Tsague, G, Ngunjiri, JW, Nguyen, AH, Nguyen, DH, Nguyen, HTH, Nguyen, N, Nguyen, NNY, Nguyen, PT, Nguyen, QP, Nguyen, VT, Nguyen Tran Minh, D, Niazi, RK, Nigatu, YT, Niknam, M, Nikoobar, A, Nikpoor, AR, Nikravangolsefid, N, Noman, EA, Nomura, S, Noor, STA, Noroozi, N, Nouri, M, Nozari, M, Nri-Ezedi, CA, Ntaios, G, Nunemo, MH, Nurrika, D, Nutor, JJ, Nzoputam, CI, Nzoputam, OJ, Oancea, B, Obamiro, KO, Odetokun, IA, Oduro, MS, Ogundijo, OA, Ogunfowokan, AA, Ogunkoya, A, Oguntade, AS, Oh, I-H, Ojo-Akosile, TR, Okati-Aliabad, H, Okekunle, AP, Okonji, OC, Olagunju, AT, Olatubi, MI, Oliveira, GMM, Olusanya, BO, Olusanya, JO, Oluwafemi, YD, Omar, HA, Omer, GL, Ong, S, Onie, S, Onwujekwe, OE, Opejin, AO, Ordak, M, Orish, VN, Ortiz, A, Ortiz-Prado, E, Osman, WMS, Ostojic, SM, Ostroff, SM, Osuagwu, UL, Otoiu, A, Otstavnov, SS, Ouyahia, A, Owolabi, MO, Oyeyemi, OT, Ozair, A, P A, MP, Padron-Monedero, A, Padubidri, JR, Pal, PK, Palicz, T, Pan, F, Pan, H-F, Panda-Jonas, S, Pandey, A, Pando-Robles, V, Pangaribuan, HU, Panos, GD, Panos, LD, Pantazopoulos, I, Pantea Stoian, AM, Parikh, RR, Park, E-K, Park, S, Parsons, N, Parthasarathi, A, Pasovic, M, Passera, R, Patel, J, Pathan, AR, Patil, S, Patoulias, D, Pawar, S, Pazoki Toroudi, H, Pease, SA, Peden, AE, Pedersini, P, Pensato, U, Pepito, VCF, Peprah, P, Pereira, M, Pereira, MO, Perianayagam, A, Perico, N, Perna, S, Pesudovs, K, Petermann-Rocha, FE, Pham, HT, Philip, AK, Phillips, MR, Pigeolet, M, Piradov, MA, Pisoni, E, Plotnikov, E, Poddighe, D, Polibin, RV, Poluru, R, Ponkilainen, VT, Popovic, DS, Postma, MJ, Pour-Rashidi, A, Prabhu, D, Prada, SI, Pradhan, J, Pradhan, PMS, Prashant, A, Prates, EJS, Priscilla, T, Purnobasuki, H, Purohit, BM, Puvvula, J, Qasim, NH, Qattea, I, Qazi, AS, Qian, G, Rabiee Rad, M, Radhakrishnan, V, Raeisi Shahraki, H, Rafferty, Q, Raggi, A, Raggi, C, Raheem, N, Rahim, F, Rahim, MJ, Rahimibarghani, S, Rahman, MMMR, Rahman, M, Rahman, MA, Rahman, T, Rahmani, AM, Rahmanian, M, Rahmanian, N, Rahmati, R, Rahmawaty, S, Raimondo, D, Raja, A, Rajput, P, Ramadan, M, Ramasamy, SK, Ramazanu, S, Ramteke, PW, Rana, K, Rana, RK, Ranabhat, CL, Rane, A, Rao, CR, Rao, M, Rasella, D, Rashedi, V, Rashid, AM, Rasouli-Saravani, A, Rastogi, P, Rasul, A, Rathish, D, Rathnaiah Babu, G, Rauniyar, SK, Ravangard, R, Rawaf, DL, Rawaf, S, Raza, RZ, Redwan, EMM, Reifels, L, Reitsma, MB, Remuzzi, G, Rengasamy, KRR, Reshmi, B, Resnikoff, S, Restaino, S, Reyes, LF, Rezaei, N, Rezaei, ZS, Rezaeian, M, Rhee, TG, Rickard, J, Robalik, T, Robinson-Oden, HE, Rocha, HAL, Rodrigues, M, Rodriguez, JAB, Roever, L, Romadlon, DS, Ronfani, L, Rony, MKK, Roshandel, G, Rotimi, K, Rout, HS, Roy, B, Rubagotti, E, Ruela, GDA, Rumisha, SF, Runghien, T, Russo, M, Saad, AMA, Saber, K, Saber-Ayad, MM, Sabet, CJ, Sabour, S, Sachdev, PS, Saddler, A, Sadee, BA, Sadeghi, M, Saeb, MR, Saeed, U, Safi, SZ, Sagar, R, Saghafi, A, Sagoe, D, Sahebkar, A, Sahoo, PM, Sajid, MR, Salam, N, Salamati, P, Salami, AA, Saleh, MA, Salehi, L, Salem, MR, Salemcity, AJ, Salimi, S, Samadi Kafil, H, Samargandy, S, Samodra, YL, Samy, AM, Sanabria, J, Sanna, F, Santric-Milicevic, MM, Sao Jose, BP, Saraswathy, SYI, Saravanan, A, Sarmiento-Suárez, R, Sarode, GS, Sarode, SC, Sartorius, B, Satpathy, M, Sayeed, A, Scarmeas, N, Schaarschmidt, BM, Schinckus, C, Schuermans, A, Schumacher, AE, Schutte, AE, Schwebel, DC, Schwendicke, F, Selvaraj, S, Semreen, MH, Senapati, S, Sengupta, P, Senthilkumaran, S, Serban, D, Sethi, Y, Seylani, A, Shafie, M, Shah, PA, Shahbandi, A, Shahid, S, Shahid, W, Shahsavari, HR, Shahwan, MJ, Shaikh, MA, Shalash, AS, Shamekh, A, Shamim, MA, Shanawaz, M, Shankar, A, Shannawaz, M, Sharath, M, Sharfaei, S, Sharifan, A, Sharifi-Rad, J, Sharma, A, Sharma, M, Sharma, S, Sharma, V, Shastry, RP, Shayan, M, Shekhar, S, Shenoy, RR, Shetty, M, Shetty, PH, Shetty, PK, Shi, P, 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Rao, M, Rasella, D, Rashedi, V, Rashid, AM, Rasouli-Saravani, A, Rastogi, P, Rasul, A, Rathish, D, Rathnaiah Babu, G, Rauniyar, SK, Ravangard, R, Rawaf, DL, Rawaf, S, Raza, RZ, Redwan, EMM, Reifels, L, Reitsma, MB, Remuzzi, G, Rengasamy, KRR, Reshmi, B, Resnikoff, S, Restaino, S, Reyes, LF, Rezaei, N, Rezaei, ZS, Rezaeian, M, Rhee, TG, Rickard, J, Robalik, T, Robinson-Oden, HE, Rocha, HAL, Rodrigues, M, Rodriguez, JAB, Roever, L, Romadlon, DS, Ronfani, L, Rony, MKK, Roshandel, G, Rotimi, K, Rout, HS, Roy, B, Rubagotti, E, Ruela, GDA, Rumisha, SF, Runghien, T, Russo, M, Saad, AMA, Saber, K, Saber-Ayad, MM, Sabet, CJ, Sabour, S, Sachdev, PS, Saddler, A, Sadee, BA, Sadeghi, M, Saeb, MR, Saeed, U, Safi, SZ, Sagar, R, Saghafi, A, Sagoe, D, Sahebkar, A, Sahoo, PM, Sajid, MR, Salam, N, Salamati, P, Salami, AA, Saleh, MA, Salehi, L, Salem, MR, Salemcity, AJ, Salimi, S, Samadi Kafil, H, Samargandy, S, Samodra, YL, Samy, AM, Sanabria, J, Sanna, F, Santric-Milicevic, MM, Sao Jose, BP, Saraswathy, SYI, Saravanan, A, Sarmiento-Suárez, R, Sarode, GS, Sarode, SC, Sartorius, B, Satpathy, M, Sayeed, A, Scarmeas, N, Schaarschmidt, BM, Schinckus, C, Schuermans, A, Schumacher, AE, Schutte, AE, Schwebel, DC, Schwendicke, F, Selvaraj, S, Semreen, MH, Senapati, S, Sengupta, P, Senthilkumaran, S, Serban, D, Sethi, Y, Seylani, A, Shafie, M, Shah, PA, Shahbandi, A, Shahid, S, Shahid, W, Shahsavari, HR, Shahwan, MJ, Shaikh, MA, Shalash, AS, Shamekh, A, Shamim, MA, Shanawaz, M, Shankar, A, Shannawaz, M, Sharath, M, Sharfaei, S, Sharifan, A, Sharifi-Rad, J, Sharma, A, Sharma, M, Sharma, S, Sharma, V, Shastry, RP, Shayan, M, Shekhar, S, Shenoy, RR, Shetty, M, Shetty, PH, Shetty, PK, Shi, P, Shiani, A, Shigematsu, M, Shimels, T, Shiri, R, Shittu, A, Shiue, I, Shivakumar, KM, Shool, S, Shorofi, SA, Shrestha, S, Shuval, K, Si, Y, Siddig, EE, Sidhu, JK, Silva, JP, Silva, LMLR, Silva, S, Silva, TPR, Simpson, CR, Simpson, KE, Singh, A, Singh, BB, Singh, B, Singh, H, Singh, J, Singh, P, Skou, ST, Smith, G, Sobia, F, Socea, B, Solanki, S, Soleimani, H, Soliman, SSM, Song, Y, Soyiri, IN, Spartalis, M, Spearman, S, Sreeramareddy, CT, Stanaway, JD, Stanikzai, MH, Starodubova, AV, Stein, DJ, Steiner, C, Steiropoulos, P, Stockfelt, L, Stokes, MA, Straif, K, Subedi, N, Suliankatchi Abdulkader, R, Sultana, A, Sun, J, Sundström, J, Swain, CK, Szarpak, L, Szeto, MD, Tabaee Damavandi, P, Tabarés-Seisdedos, R, Tabatabaei Malazy, O, Tabatabaeizadeh, S-A, Tabatabai, S, Tabb, KM, Tabche, C, Tabish, M, Taheri Abkenar, Y, Taheri Soodejani, M, Taiba, J, Talaat, IM, Tamuzi, JL, Tan, K-K, Tang, H, Tat, NY, Tavakoli Oliaee, R, Tavangar, SM, Taveira, N, Tbakhi, A, Tehrani, H, Temsah, M-H, Teramoto, M, Tesfaye, BT, Teye-Kwadjo, E, Thangaraju, P, Thankappan, KR, Thapar, R, Thayakaran, R, Thirunavukkarasu, S, Thomas, N, Thygesen, LC, Ticoalu, JHV, Timalsena, D, Tiruye, TY, Tiwari, K, Tomo, S, Tonelli, M, Topor-Madry, R, Touvier, M, Tovani-Palone, MR, Tran, AT, Tran, JT, Tran, NM, Tran, TH, Trico, D, Tromans, SJ, Truyen, TTTT, Tsatsakis, A, Tsermpini, EE, Tumurkhuu, M, Turnock, ST, Udoh, A, Ullah, A, Ullah, S, Umakanthan, S, Umar, M, Umar, SS, Unim, B, Unnikrishnan, B, Upadhyay, E, Usman, JS, Vahdati, S, Vaithinathan, AG, Vakili, O, Valizadeh, R, Van den Eynde, J, Vart, P, Varthya, SB, Vasankari, TJ, Vasic, M, Venketasubramanian, N, Veroux, M, Verras, G-I, Vervoort, D, Vijayageetha, M, Villafañe, JH, Vinayak, M, Violante, FS, Vladimirov, SK, Vlassov, V, Vo, B, Vohra, K, Vos, T, Wadood, AW, Waheed, Y, Wang, F, Wang, S, Wang, Y, Wang, Y-P, Wanjau, MN, Waqas, M, Ward, P, Waris, A, Wassie, EG, Watson, S, Weaver, MR, Weerakoon, KG, Weintraub, RG, Weldetinsaa, HLL, Wells, KM, Wen, YF, Westerman, R, Wiangkham, T, Wickramasinghe, DP, Widowati, E, Wojewodzic, MW, Woldeyes, DH, Wolf, AW, Wolfe, CDA, Wu, C, Wu, D, Wu, F, Wu, J, Wu, Z, Wulf Hanson, S, Xiao, H, Xu, S, Yadav, R, Yamagishi, K, Yang, D, Yano, Y, Yarahmadi, A, Yazdani Nia, I, Ye, P, Yesodharan, R, Yesuf, SA, Yezli, S, Yiğit, A, Yiğit, V, Yigzaw, ZA, Yin, D, Yip, P, Yonemoto, N, You, Y, Younis, MZ, Yu, C, Yu, EA, Yu, Y, Yuan, C-W, Yusuf, H, Zafar, U, Zafari, N, Zahid, MH, Zakham, F, Zaki, N, Zerfu, TA, Zhang, H, Zhang, J, Zhang, L, Zhang, Y, Zhang, Z, Zhao, X-JG, Zhao, Y, Zhao, Z, Zhong, C, Zhou, B, Zhou, J, Zhou, S, Zhu, B, Zhumagaliuly, A, Zielińska, M, Zoghi, G, Zumla, A, Zyoud, SH, Smith, AE, and Murray, CJL
Published: 2024

2. Reduced real lifetime of PV panels – Economic consequences

Author: Martin Libra, David Mrázek, Igor Tyukhov, Lucie Severová, Vladislav Poulek, Jiří Mach, Tomáš Šubrt, Václav Beránek, Roman Svoboda, and Jan Sedláček
Subjects: Renewable Energy, Sustainability and the Environment, General Materials Science
Published: 2023

3. Prebiotics and the Risk of Upper Digestive Tract and Stomach Cancers: The PrebiotiCa Study

Author: Turati, Federica, primary, Concina, Federica, additional, Bertuccio, Paola, additional, Fiori, Federica, additional, Parpinel, Maria, additional, Garavello, Werner, additional, Crispo, Anna, additional, Libra, Massimo, additional, Negri, Eva, additional, Serraino, Diego, additional, and La Vecchia, Carlo, additional
Published: 2023
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4. Reduced real lifetime of PV panels – Economic consequences

Author: Libra, Martin, primary, Mrázek, David, additional, Tyukhov, Igor, additional, Severová, Lucie, additional, Poulek, Vladislav, additional, Mach, Jiří, additional, Šubrt, Tomáš, additional, Beránek, Václav, additional, Svoboda, Roman, additional, and Sedláček, Jan, additional
Published: 2023
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5. SnapShot: Cancer chemotherapy

Author: Falzone, Luca, primary, Bordonaro, Roberto, additional, and Libra, Massimo, additional
Published: 2023
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6. Removal of RhB from water by Fe-modified hydrochar and biochar – An experimental evaluation supported by genetic programming

Author: Kohzadi, Shadi, primary, Marzban, Nader, additional, Libra, Judy A., additional, Bundschuh, Mirco, additional, and Maleki, Afshin, additional
Published: 2023
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7. Experimental evaluation and application of genetic programming to develop predictive correlations for hydrochar higher heating value and yield to optimize the energy content

Author: Marzban, Nader, primary, Libra, Judy A., additional, Hosseini, Seyyed Hossein, additional, Fischer, Marcus G., additional, and Rotter, Vera Susanne, additional
Published: 2022
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8. Superior mesenteric artery syndrome (Wilkie Syndrome) with unusual clinical onset: Description of a rare case

Author: Guido Basile, M. Coronella, Antonio Basile, Elena Lamirata, Federica Libra, Isabella Pennisi, Tiziana Vasile, Renato Farina, Cecilia Gozzo, Pietro Valerio Foti, Alessia Di Mari, and Massimiliano Veroux
Subjects: medicine.medical_specialty, Superior Mesenteric Artery Syndrome, business.industry, Cardiovascular Abnormalities, R895-920, Case Report, medicine.disease, Epigastric pain, Surgery, Medical physics. Medical radiology. Nuclear medicine, Stenosis, Nutcracker syndrome, Computed Tomography, medicine.anatomical_structure, Weight loss, Wilkie's Syndrome, medicine, Vomiting, Duodenum, Radiology, Nuclear Medicine and imaging, Doppler Ultrasound, medicine.symptom, business, Superior mesenteric artery syndrome, Rare disease
Abstract: Wilkie's Syndrome is a very rare disease caused by reduction of aorto-mesenteric space with consequent duodenum compression. It can combine with left renal vein stenosis which, when symptomatic, is known as ''Nutcracker Syndrome''. We describe a clinical onset case with epigastric pain without vomiting in a normal weight patient. 28-year-old woman who came to our observation for intense epigastric pain after a weight loss of 14 kg in 4 months. Multidetector Computed Tomography and Ultrasound revealed gastric and duodenal overdistension with hydro-air levels, severe duodenum stenosis, and left renal vein compression. Wilkie's Syndrome is common in anorexic individuals suffering from recurrent postprandial vomiting, onset with severe epigastric pain, without vomiting, is quite unusual. High-calorie diet must be first therapeutic approach, in case of failure treatment of first choice should be endovascular stenting and, only in selected cases, surgical treatment should be used because it is very invasive and burdened with numerous complications. Failure to diagnose this disease can expose patients to serious health risks.
Published: 2021

9. Endovascular treatment of a rare case of haemobilia caused by both pseudoaneurysm and a giant hepatic haemangioma

Author: Basile Antonio, Palmucci Stefano, Santonocito Serafino, Libra Federica, Failla Giovanni, and Falsaperla Daniele
Subjects: lcsh:Medical physics. Medical radiology. Nuclear medicine, medicine.medical_specialty, Abdominal pain, lcsh:R895-920, Hepatic pseudoaneurysm, Case Report, TACE, transarterial chemoembolization, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, Pseudoaneurysm, 0302 clinical medicine, Hepatic haemangioma, Pathognomonic, Melena, HAP, hepatic artery pseudoaneurysm, Medicine, Endocarditis, Endovascular treatment, Radiology, Nuclear Medicine and imaging, TAE, transarterial embolization, business.industry, SMA, superior mesenteric artery, Haemobilia, Jaundice, medicine.disease, RHA, right hepatic artery, TAL, lipiodolization, Transarterial embolization (TAE), Etiology, CTA, computed tomography angiography, Radiology, medicine.symptom, business, 030217 neurology & neurosurgery
Abstract: Haemobilia is defined as bleeding from the biliary system due to abnormal communication between a blood vessel and the bile ducts. Melena or hematemesis, abdominal pain and jaundice represent the pathognomonic triad for haemobilia, but clinical presentation and aetiology of this entity are extremely variable. We report a case of a 50-year-old man with melena and anaemia and a clinical history of multivalvular endocarditis in which an extremely rare presence of 2 uncommon causes of haemobilia was found, such as a mycotic pseudoaneurysm and a giant hepatic haemangioma, both treated by transarterial embolization. In the management of haemobilia, TAE has been proven to be the treatment of choice because it combines a diagnostic angiography with therapeutic intervention in a minimally invasive, safe and effective way. Physician and radiologist should keep in mind also the uncommon aetiologies of haemobilia, knowing that the source of bleeding could be more than just one.
Published: 2021

10. SnapShot: Cancer chemotherapy

Author: Luca Falzone, Roberto Bordonaro, and Massimo Libra
Subjects: General Biochemistry, Genetics and Molecular Biology
Published: 2023

11. Determinants of Vitamin D Levels in Women Treated for Breast Cancer: a baseline analysis of data from DEDiCa trial

Author: Fassio, Angelo, primary, Adami, Giovanni, additional, Augustin, Livia, additional, Montagnese, Concetta, additional, Rossini, Maurizio, additional, Carioli, Greta, additional, Libra, Massimo, additional, Celentano, Egidio, additional, La Vecchia, Carlo, additional, and Gatti, Davide, additional
Published: 2022
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12. Theoretical framework for estimating design reactor pressure for water-based hydrothermal carbonization (HTC) systems

Author: Alvarez-Murillo, Andrés, primary, Libra, Judy A., additional, and Ro, Kyoung S., additional
Published: 2022
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13. Removal of RhB from water by Fe-modified hydrochar and biochar – An experimental evaluation supported by genetic programming

Author: Shadi Kohzadi, Nader Marzban, Judy A. Libra, Mirco Bundschuh, and Afshin Maleki
Subjects: Materials Chemistry, Physical and Theoretical Chemistry, Condensed Matter Physics, Spectroscopy, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials
Published: 2023

14. Experimental evaluation and application of genetic programming to develop predictive correlations for hydrochar higher heating value and yield to optimize the energy content

Author: Nader Marzban, Judy A. Libra, Seyyed Hossein Hosseini, Marcus G. Fischer, and Vera Susanne Rotter
Subjects: Process Chemistry and Technology, Chemical Engineering (miscellaneous), Pollution, Waste Management and Disposal
Published: 2022

15. Effects of the MDM2 inhibitor Nutlin-3a on sensitivity of pancreatic cancer cells to berberine and modified berberines in the presence and absence of WT-TP53

Author: Abrams, Stephen L., primary, Akula, Shaw M., additional, Steelman, Linda S., additional, Follo, Matilde L., additional, Cocco, Lucio, additional, Ratti, Stefano, additional, Martelli, Alberto M., additional, Libra, Massimo, additional, Falzone, Luca, additional, Candido, Saverio, additional, Montalto, Giuseppe, additional, Cervello, Melchiorre, additional, Lombardi, Paolo, additional, and McCubrey, James A., additional
Published: 2022
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16. Effects of the MDM2 inhibitor Nutlin-3a on sensitivity of pancreatic cancer cells to berberine and modified berberines in the presence and absence of WT-TP53

Author: Paolo Lombardi, Giuseppe Montalto, Lucio Cocco, Massimo Libra, Matilde L. Follo, James A. McCubrey, Shaw M. Akula, Stephen L. Abrams, Luca Falzone, Linda S. Steelman, Melchiorre Cervello, Saverio Candido, Stefano Ratti, Alberto M. Martelli, Abrams S.L., Akula S.M., Steelman L.S., Follo M.Y., Cocco L., Ratti S., Martelli A.M., Libra M., Falzone L., Candido S., Montalto G., Cervello M., Lombardi P., and McCubrey J.A.
Subjects: Nutlin-3a, Cancer Research, Berberine, endocrine system diseases, Tumor suppressor gene, NAX compounds, Apoptosis, Piperazines, Targeted therapy, Gene product, Cell Line, Tumor, Pancreatic cancer, Genetics, medicine, Humans, TP53, neoplasms, Molecular Biology, Regulator gene, NAX compunds, biology, Chemistry, Imidazoles, PDAC, Cancer, Proto-Oncogene Proteins c-mdm2, PDCA, medicine.disease, Ubiquitin ligase, Pancreatic Neoplasms, Cell culture, biology.protein, Cancer research, NAX compound, Molecular Medicine, Mdm2, Tumor Suppressor Protein p53, Signal Transduction
Abstract: Approaches to improve pancreatic cancer therapy are essential as this disease has a very bleak outcome. Approximately 80% of pancreatic cancers are pancreatic ductal adenocarcinomas (PDAC). A key regulatory gene frequently mutated (∼75%) in PDAC is the TP53 tumor suppressor gene which controls the transcription of multiple genes involved in cell cycle progression, apoptosis, cancer progression and other growth regulatory processes. The mouse double minute 2 homolog (MDM2) gene product is a nuclear-localized E3 ubiquitin ligase and negatively regulates the TP53 protein which results in its proteasomal degradation. Various MDM2 inhibitors have been isolated and examined in clinical trials, especially in patients with hematological malignancies. Nutlin-3a is one of the first MDM2 inhibitors isolated. Berberine (BBR) is a natural product found in many fruits and berries and used in traditional medicine for centuries. It has many biological effects, and some are anti-proliferative in nature. BBR may activate the expression of TP53 and inhibit cell cycle progression as well as other events important in cell growth. To understand more about the potential of compounds like BBR and chemical modified BBRs (NAX compounds) to sensitize PDAC cells to MDM2 inhibitors, we introduced either WT-TP53 or the pLXSN empty vector control into two PDAC cell lines, one lacking expression of TP53 (PANC-28) and one with gain-of-function mutant TP53 on both alleles (MIA-PaCa-2). Our results indicate that nutlin-3a was able to increase the sensitivity to BBR and certain NAX compounds. The effects of nutlin-3a were usually more substantial in those cells containing an introduced WT TP53 gene. These results highlight the importance of knowledge of the type of TP53 mutation that is present in cancer patients before the administration of drugs which function by stabilization of the TP53 protein.
Published: 2022

17. The dietary inflammatory index in women diagnosed with breast cancer after 12 months of dietary. Treatment with a Mediterranean diet low in glycemic index: data from DEDICA randomized controlled trial

Author: Vitale, S., primary, Mattioli, V., additional, Shivappa, N., additional, Hebert, J.R., additional, Palumbo, E., additional, Porciello, G., additional, Montagnese, C., additional, Calabrese, I., additional, Pica, R., additional, Prete, M., additional, Luongo, A., additional, Grimaldi, M., additional, Crispo, A., additional, Falzone, L., additional, Libra, M., additional, Polesel, J., additional, Serraino, D., additional, Poletto, L., additional, Martinuzzo, V., additional, Gatti, D., additional, Thomas, G., additional, De Laurentiis, M., additional, D'Aiuto, M., additional, Pinto, M., additional, Cianniello, D., additional, Pacilio, C., additional, Rinaldo, M., additional, Riccardi, G., additional, Jenkins, D.J.A., additional, Botti, G., additional, and Augustin, L.S.A., additional
Published: 2021
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18. Superior mesenteric artery syndrome (Wilkie Syndrome) with unusual clinical onset: Description of a rare case

Author: Farina, Renato, primary, Foti, Pietro Valerio, additional, Coronella, Maria, additional, Pennisi, Isabella, additional, Libra, Federica, additional, Di Mari, Alessia, additional, Gozzo, Cecilia, additional, Vasile, Tiziana, additional, Lamirata, Elena, additional, Veroux, Massimiliano, additional, Basile, Guido, additional, and Basile, Antonio, additional
Published: 2021
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19. Intelligent modeling and experimental study on methylene blue adsorption by sodium alginate-kaolin beads

Author: Marzban, Nader, primary, Moheb, Ahmad, additional, Filonenko, Svitlana, additional, Hosseini, Seyyed Hossein, additional, Nouri, Mohammad Javad, additional, Libra, Judy A., additional, and Farru, Gianluigi, additional
Published: 2021
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20. Limiting and timing water supply for agricultural production – The case of the Zayandeh-Rud River Basin, Iran

Author: Judy A. Libra, Philipp Grundmann, Omid Zamani, and Alireza Nikouei
Subjects: Irrigation, business.industry, 0208 environmental biotechnology, Soil Science, Water supply, 04 agricultural and veterinary sciences, 02 engineering and technology, Gross margin, Irrigation district, 020801 environmental engineering, Water scarcity, Agriculture, Agricultural land, 040103 agronomy & agriculture, 0401 agriculture, forestry, and fisheries, Environmental science, Agricultural productivity, business, Water resource management, Agronomy and Crop Science, Earth-Surface Processes, Water Science and Technology
Abstract: The present study investigates alternative scenarios of timing and reduced water supply in terms of their impacts on agricultural land use, farm revenue and food crop production. It aims to evaluate the implications for the development of different farming systems in one of the most water-scarce irrigation districts in the Zayandeh-Rud River Basin in central Iran, the Roudasht irrigation district. A modified version of Positive Mathematical Programming (PMP) model was used to assess the scenarios. The results from the scenario simulations illustrate that there is substantial potential for improving the management of the limited water supply in the Roudasht irrigation network to reach higher water productivity, agricultural output and gross margins from agricultural activities. A management plan to target a limit in the irrigation water supply only for the month of peak demand, e.g. 60% to 80% of the baseline water supply for May in Roudasht, may have less adverse effects than planning to limit the annual water supply by the same amount but without specifying the monthly timing of the water supply. These results highlight the relevance and impact of the timing of water supply when devising adaptive measures related to the irrigation water supply.
Published: 2019

21. Identification of epsilon toxin-producing Clostridium perfringens strains in American retail food

Author: Libra B. Williams, Juan Sepulveda, Anthony Vartanian, Sam Bogdanov, Patricia Miraflor, Samantha B. Regan, Steffi Gaehde, Jennifer R. Linden, Noah Rubin, Sarah Shetty, Jake Moreh, Abigail Lustig, Zuha Anwar, and Sylvia Haigh
Subjects: 0301 basic medicine, Meat, Clostridium perfringens, Toxin, Bacterial Toxins, 030106 microbiology, Fishes, Food Contamination, Biology, medicine.disease_cause, Microbiology, Poultry, United States, 03 medical and health sciences, Infectious Diseases, Seafood, Retail food, Genotype, medicine, Animals, Cattle, Identification (biology), Gene
Abstract: Food samples (n = 216) from New York city were tested for the presence of C. perfringens via PCR for specific toxin genes. Thirty-four (16%) samples were positive for C. perfringens. Of these 34, 31 (91.2%) were type A or E, one (2.9%) was type B, and two (5.9%) were type D.
Published: 2018

22. Theoretical framework for estimating design reactor pressure for water-based hydrothermal carbonization (HTC) systems

Author: Andrés Alvarez-Murillo, Judy A. Libra, and Kyoung S. Ro
Subjects: Fluid Flow and Transfer Processes
Published: 2022

23. Determinants of Vitamin D Levels in Women Treated for Breast Cancer: a baseline analysis of data from DEDiCa trial

Author: Angelo Fassio, Giovanni Adami, Livia Augustin, Concetta Montagnese, Maurizio Rossini, Greta Carioli, Massimo Libra, Egidio Celentano, Carlo La Vecchia, and Davide Gatti
Subjects: Endocrinology, Diabetes and Metabolism, Orthopedics and Sports Medicine
Published: 2022

24. Dietary water intake and bladder cancer risk: An Italian case–control study

Author: Maria Parpinel, Monica Ferraroni, Jerry Polesel, Massimo Libra, Antonella Zucchetto, Carlo La Vecchia, Alessandra Tavani, Federica Turati, Maurizio Montella, Martina Taborelli, Cristina Bosetti, Eva Negri, Matteo Di Maso, Diego Serraino, M. Di Maso, C. Bosetti, M. Taborelli, M. Montella, M. Libra, A. Zucchetto, F. Turati, M. Parpinel, E. Negri, A. Tavani, D. Serraino, M. Ferraroni, C. La Vecchia, and J. Polesel
Subjects: Adult, Male, Cancer Research, Case–control study, Epidemiology, Bladder cancer, Diet, Dietary water intake, Fluids, Logistic regression, Beverages, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Environmental health, Odds Ratio, medicine, Humans, 030212 general & internal medicine, Food science, Water content, Aged, Aged, 80 and over, business.industry, Drinking Water, Case-control study, Odds ratio, Middle Aged, medicine.disease, Confidence interval, Transitional cell carcinoma, Italy, Urinary Bladder Neoplasms, Oncology, Quartile, Case-Control Studies, 030220 oncology & carcinogenesis, Female, business, Water Pollutants, Chemical
Abstract: Previous studies on the relationship between fluid intake and risk of bladder cancer have generally focused on beverages, and results have been inconsistent. We investigated the relationship between water intake and bladder cancer risk, considering water from both beverages and foods. Between 2003 and 2014 we conducted a multicenter hospital-based case-control study in Italy on 690 cases and 665 frequency-matched controls. Water intake for beverages and foods was computed using the Italian food composition database. Odds ratios (ORs) and the corresponding 95% confidence intervals (95%CIs) for water intake were estimated by unconditional multiple logistic regression models, adjusting for major risk factors for bladder cancer. In the control group, the 64.7% of water intake derived from beverages and 35.4% from foods. Comparing the highest with the lowest quartile of intake, water from beverages (OR=1.14; 95%CI: 0.82-1.59) and water from foods (OR=0.88; 95%CI: 0.61-1.28) were not significantly associated with bladder cancer risk. Some specific water sources showed significant associations with bladder cancer risk (e.g. water from vegetables, OR=0.58; 95%CI: 0.40-0.86). However, these associations may be due to the effect of other components contained in beverages and foods rather than to the water content itself. Considering the intakes of water from both beverages and foods, total water intake was not associated with bladder cancer risk.
Published: 2016

25. Interaction between matrix metalloproteinase-9 (MMP-9) and neutrophil gelatinase-associated lipocalin (NGAL): A recent evolutionary event in primates

Author: D'Amico, Fabio, primary, Candido, Saverio, additional, and Libra, Massimo, additional
Published: 2021
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26. Endovascular treatment of a rare case of haemobilia caused by both pseudoaneurysm and a giant hepatic haemangioma

Author: Libra, Federica, primary, Santonocito, Serafino, additional, Falsaperla, Daniele, additional, Failla, Giovanni, additional, Palmucci, Stefano, additional, and Basile, Antonio, additional
Published: 2021
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27. Elevated CO 2 Accelerates Phosphorus Depletion by Common Bean ( Phaseolus vulgaris ) in Association with Altered Leaf Biochemical Properties

Author: Zechuan Shi, Zhong Ma, Grant Libra, and Jennifer Flynn
Subjects: 0106 biological sciences, Limiting factor, biology, Phosphorus, fungi, Lateral root, Acid phosphatase, food and beverages, Soil Science, chemistry.chemical_element, 04 agricultural and veterinary sciences, biology.organism_classification, 01 natural sciences, chemistry.chemical_compound, Animal science, Agronomy, chemistry, Chlorophyll, 040103 agronomy & agriculture, biology.protein, 0401 agriculture, forestry, and fisheries, Biomass partitioning, Phaseolus, Respiration rate, 010606 plant biology & botany
Abstract: Phosphorus (P) is a major limiting factor for plant productivity in many ecosystems and agriculture. The projected increase in atmospheric CO 2 is likely to result in changes in plant mineral consumption and growth. We studied phosphorus depletion by common bean plants cultured hydroponically under ambient (377 ± 77 µmol mol −1 ) or elevated (650 ± 32 µmol mol −1 ) CO 2, in media of low or high phosphorus. Compared to ambient CO 2 environment, under elevated CO 2 : 1) maximum phosphorus depletion rate increased by 98% at low phosphorus and 250% at high phosphorus, and phosphorus was depleted about 2 to 5 weeks sooner; 2) leaf acid phosphatase (APase) activity and leaf chlorophyll content both increased significantly; 3) root-to-shoot ratio increased significantly at high phosphorus, although it was unaffected at low phosphorus; 4) lateral root respiration rate had no change, suggesting that CO 2 did not affect phosphorus depletion via metabolic changes to the roots; 5) total biomass at final harvest was significantly higher at both low- and high- phosphorus. Our data show that the increased rate and amount of phosphorus depletion during growth under elevated CO 2 occurred in association with alteration in leaf biochemical properties, i.e., enhanced activities of leaf APase and increased leaf chlorophyll content.
Published: 2018

28. Influence of increased temperature on energy production of roof integrated PV panels

Author: E. Kachalouski, Vladislav Poulek, J. Sedláček, Tomas Matuska, and M. Libra
Subjects: business.industry, 020209 energy, Mechanical Engineering, 02 engineering and technology, Building and Construction, Structural engineering, 021001 nanoscience & nanotechnology, Technical university, 0202 electrical engineering, electronic engineering, information engineering, Environmental science, Production (economics), Electrical and Electronic Engineering, Thermal model, 0210 nano-technology, business, Roof, Civil and Structural Engineering
Abstract: A temperature of roof integrated PV panels can increase substantially in comparison with that of free standing PV panels. Energy production of roof integrated PV panels can be reduced substantially. The temperature and energy production of roof integrated and free standing PV panels was investigated at the Czech University of Life Sciences (CULS) in Prague. The annual difference 3.2 K in temperature and 3.5% in energy production between roof integrated and free standing PV panels has been evaluated. The experimental results of the measurement of roof integrated panels have verified the new simplified thermal model of PV panel developed at Czech Technical University (CTU). The model has been used for further analysis of PV panel performance in different climates. While roof integration of PV panel in cold, moderate and warm climate (Stockholm, Prague, Athens) brings only reduction of energy production by several percents, it could lead to exposition to very high temperatures in hot climate (Riyadh) and cause an accelerated degradation of PV panels.
Published: 2018

29. Greenhouse gas emissions from broiler manure treatment options are lowest in well-managed biogas production

Author: Kreidenweis, Ulrich, primary, Breier, Jannes, additional, Herrmann, Christiane, additional, Libra, Judy, additional, and Prochnow, Annette, additional
Published: 2021
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30. Sensitivity of pancreatic cancer cells to chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals can be regulated by WT-TP53

Author: Abrams, Stephen L., primary, Akula, Shaw M., additional, Martelli, Alberto M., additional, Cocco, Lucio, additional, Ratti, Stefano, additional, Libra, Massimo, additional, Candido, Saverio, additional, Montalto, Giuseppe, additional, Cervello, Melchiorre, additional, Gizak, Agnieszka, additional, Rakus, Dariusz, additional, Steelman, Linda S., additional, and McCubrey, James A., additional
Published: 2021
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31. SARS-CoV-2 pathophysiology and its clinical implications: An integrative overview of the pharmacotherapeutic management of COVID-19

Author: Tsatsakis, Aristides, primary, Calina, Daniela, additional, Falzone, Luca, additional, Petrakis, Dimitrios, additional, Mitrut, Radu, additional, Siokas, Vasileios, additional, Pennisi, Manuela, additional, Lanza, Giuseppe, additional, Libra, Massimo, additional, Doukas, Sotirios G., additional, Doukas, Panagiotis G., additional, Kavali, Leena, additional, Bukhari, Amar, additional, Gadiparthi, Chiranjeevi, additional, Vageli, Dimitra P., additional, Kofteridis, Diamantis P., additional, Spandidos, Demetrios A., additional, Paoliello, Monica M.B., additional, Aschner, Michael, additional, and Docea, Anca Oana, additional
Published: 2020
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32. Therapeutic resistance in breast cancer cells can result from deregulated EGFR signaling

Author: Steelman, Linda S., primary, Chappell, William H., additional, Akula, Shaw M., additional, Abrams, Stephen L., additional, Cocco, Lucio, additional, Manzoli, Lucia, additional, Ratti, Stefano, additional, Martelli, Alberto M., additional, Montalto, Giuseppe, additional, Cervello, Melchiorre, additional, Libra, Massimo, additional, Candido, Saverio, additional, and McCubrey, James A., additional
Published: 2020
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33. The dietary inflammatory index in women diagnosed with breast cancer after 12 months of dietary. Treatment with a Mediterranean diet low in glycemic index: data from DEDICA randomized controlled trial

Author: Massimo Libra, M. Pinto, S. Vitale, James R. Hébert, Anna Crispo, Nitin Shivappa, Concetta Montagnese, M. De Laurentiis, G. Botti, Melania Prete, Daniela Cianniello, L. S. A. Augustin, Elvira Palumbo, Massimiliano D’Aiuto, Gabriele Riccardi, J. Polesel, Luigina Poletto, Diego Serraino, Giuseppe Porciello, Massimo Rinaldo, Ilaria Calabrese, Rosita Pica, Carmen Pacilio, Valentina Martinuzzo, Guglielmo Thomas, V. Mattioli, A. Luongo, Davide Gatti, David J.A. Jenkins, Maria Grazia Grimaldi, and Luca Falzone
Subjects: medicine.medical_specialty, Nutrition and Dietetics, Index (economics), Mediterranean diet, business.industry, Endocrinology, Diabetes and Metabolism, Medicine (miscellaneous), medicine.disease, law.invention, Breast cancer, Glycemic index, Randomized controlled trial, Dietary treatment, law, Internal medicine, Medicine, Cardiology and Cardiovascular Medicine, business
Published: 2021

34. Cancer therapy and treatments during COVID-19 era

Author: Akula, Shaw M., primary, Abrams, Stephen L., additional, Steelman, Linda S., additional, Candido, Saverio, additional, Libra, Massimo, additional, Lerpiriyapong, Kvin, additional, Cocco, Lucio, additional, Ramazzotti, Giulia, additional, Ratti, Stefano, additional, Follo, Matilde Y., additional, Martelli, Alberto M., additional, Blalock, William L., additional, Piazzi, Manuela, additional, Montalto, Giuseppe, additional, Cervello, Melchiorre, additional, Notarbartolo, Monica, additional, Basecke, Jorg, additional, and McCubrey, James A., additional
Published: 2020
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35. Spontaneous bleeding in systemic lupus erythematosus: Endovascular treatment of two rare cases

Author: Libra, Federica, primary, Falsaperla, Daniele, additional, Desiderio, Carla Maria, additional, Signorelli, Salvatore Santo, additional, Palmucci, Stefano, additional, and Basile, Antonio, additional
Published: 2020
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36. Effect of a low glycemic index Mediterranean diet on cardiovascular risk factors in women diagnosed with breast cancer: preliminary data from DEDiCa study

Author: Montagnese, C., primary, Porciello, G., additional, Vitale, S., additional, Palumbo, E., additional, Calabrese, I., additional, Crispo, A., additional, Grimaldi, M., additional, Pica, R., additional, Marotta, V., additional, Esindi, N., additional, Prete, M., additional, Cubisino, S., additional, Falzone, L., additional, De Laurentiis, M., additional, Rinaldo, M., additional, D’Aiuto, M., additional, Cianniello, D., additional, Pacilio, C., additional, Pinto, M., additional, Thomas, G., additional, Catalano, F., additional, Banna, G., additional, Ursino, V., additional, Ferrau’, F., additional, Rossello, R., additional, Serraino, D., additional, Massarut, S., additional, Poletto, L., additional, Martinuzzo, V., additional, Guerra, G., additional, Farina, A., additional, Messina, F., additional, Cavalcanti, E., additional, Minopoli, A., additional, Fiorillo, P., additional, Grilli, B., additional, Cuomo, M., additional, Comegna, C., additional, Cervo, S., additional, Evangelista, C., additional, Bolzicco, D., additional, Steffan, A., additional, Riccardi, G., additional, Jenkins, D.J.A., additional, Gatti, D., additional, Libra, M., additional, Celentano, E., additional, Botti, G., additional, and Augustin, L.S.A., additional
Published: 2020
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37. Abilities of β-Estradiol to interact with chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals and alter the proliferation of pancreatic cancer cells

Author: Akula, Shaw M., primary, Candido, Saverio, additional, Abrams, Stephen L., additional, Steelman, Linda S., additional, Lertpiriyapong, Kvin, additional, Cocco, Lucio, additional, Ramazzotti, Giulia, additional, Ratti, Stefano, additional, Follo, Matilde Y., additional, Martelli, Alberto M., additional, Murata, Ramiro M., additional, Rosalen, Pedro L., additional, Bueno-Silva, Bruno, additional, Matias de Alencar, Severino, additional, Falasca, Marco, additional, Montalto, Giuseppe, additional, Cervello, Melchiorre, additional, Notarbartolo, Monica, additional, Gizak, Agnieszka, additional, Rakus, Dariusz, additional, Libra, Massimo, additional, and McCubrey, James A., additional
Published: 2020
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38. The Morphological Domain Does Not Affect the Rate of Progression to Defined Autoimmune Diseases in Patients With Interstitial Pneumonia With Autoimmune Features

Author: Sambataro, Gianluca, primary, Vancheri, Ada, additional, Torrisi, Sebastiano E., additional, Colaci, Michele, additional, Pavone, Mauro, additional, Libra, Alessandro, additional, Martorana, Emanuele, additional, Rosso, Roberta, additional, Pignataro, Francesca, additional, Del Papa, Nicoletta, additional, Malatino, Lorenzo, additional, Palmucci, Stefano, additional, Sambataro, Domenico, additional, and Vancheri, Carlo, additional
Published: 2020
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39. Food consumption, meat cooking methods and diet diversity and the risk of bladder cancer

Author: Di Maso, Matteo, primary, Turati, Federica, additional, Bosetti, Cristina, additional, Montella, Maurizio, additional, Libra, Massimo, additional, Negri, Eva, additional, Ferraroni, Monica, additional, La Vecchia, Carlo, additional, Serraino, Diego, additional, and Polesel, Jerry, additional
Published: 2019
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40. Effect of a low glycemic index Mediterranean diet on cardiovascular risk factors in women diagnosed with breast cancer: preliminary data from DEDiCa study

Author: C. Montagnese, G. Porciello, S. Vitale, E. Palumbo, I. Calabrese, A. Crispo, M. Grimaldi, R. Pica, V. Marotta, N. Esindi, M. Prete, S. Cubisino, L. Falzone, M. De Laurentiis, M. Rinaldo, M. D’Aiuto, D. Cianniello, C. Pacilio, M. Pinto, G. Thomas, F. Catalano, G. Banna, V. Ursino, F. Ferrau’, R. Rossello, D. Serraino, S. Massarut, L. Poletto, V. Martinuzzo, G. Guerra, A. Farina, F. Messina, E. Cavalcanti, A. Minopoli, P. Fiorillo, B. Grilli, M. Cuomo, C. Comegna, S. Cervo, C. Evangelista, D. Bolzicco, A. Steffan, G. Riccardi, D.J.A. Jenkins, D. Gatti, M. Libra, E. Celentano, G. Botti, and L.S.A. Augustin
Subjects: Nutrition and Dietetics, Endocrinology, Diabetes and Metabolism, Medicine (miscellaneous), Cardiology and Cardiovascular Medicine
Published: 2020

41. Roof photovoltaic power plant operation during the solar eclipse

Author: Václav Beránek, J. Sedláček, Vladislav Poulek, M. Libra, and I.I. Tyukhov
Subjects: Amorphous silicon, Renewable Energy, Sustainability and the Environment, business.industry, Solar eclipse, 020209 energy, Photovoltaic system, Photovoltaic mounting system, 02 engineering and technology, Engineering physics, chemistry.chemical_compound, chemistry, Photovoltaics, 0202 electrical engineering, electronic engineering, information engineering, Grid-connected photovoltaic power system, Environmental science, General Materials Science, business, Roof, Eclipse
Abstract: The article describes the construction of the photovoltaic (PV) system and shows the unique data measured during the solar eclipse on the 20th of March 2015. The data are discussed. The PV power plant was installed on the roof of the football stadium in the year 2010. Considering the location on the atypical roof and integration into the architectural style of the surroundings, flexible photovoltaic foils based on thin semiconducting layers of amorphous silicon oriented horizontally were used at this location. Some data obtained during five-year operation and testing of the PV power plant are also presented.
Published: 2016

42. Roles of EGFR and KRAS and their downstream signaling pathways in pancreatic cancer and pancreatic cancer stem cells

Author: James A. McCubrey, Timothy L. Fitzgerald, Saverio Candido, Giuseppe Montalto, Lucio Cocco, Linda S. Steelman, Massimo Libra, Melchiorre Cervello, Alberto M. Martelli, Stephen L. Abrams, Kvin Lertpiriyapong, Fitzgerald, T., Lertpiriyapong, K., Cocco, L., Martelli, A., Libra, M., Candido, S., Montalto, G., Cervello, M., Steelman, L., Abrams, S., Mccubrey, J., Martelli, A.M., Abrams, S.L., and Mccubrey, J.A. .
Subjects: MAPK/ERK pathway, Cancer Research, miRs, EGFR, medicine.disease_cause, Metastasis, Proto-Oncogene Proteins p21(ras), Glycogen Synthase Kinase 3, Genetic, Cancer stem cell, KRa, Pancreatic cancer, KRas, Genetics, medicine, Animals, Humans, PTEN, Epidermal growth factor receptor, Molecular Biology, PI3K/AKT/mTOR pathway, GSK-3, biology, Cancer stem cells, miR, Drug resistance, Metformin, medicine.disease, ErbB Receptors, Pancreatic Neoplasms, Neoplastic Stem Cells, biology.protein, Cancer research, Molecular Medicine, KRAS, Signal Transduction
Abstract: Pancreatic cancer is currently the fourth most common cancer, is increasing in incidence and soon will be the second leading cause of cancer death in the USA. This is a deadly malignancy with an incidence that approximates the mortality with 44,000 new cases and 36,000 deaths each year. Surgery, although only modestly successful, is the only curative option. However, due the locally aggressive nature and early metastasis, surgery can be performed on less than 20% of patients. Cytotoxic chemotherapy is palliative, has significant toxicity and improves survival very little. Thus new treatment paradigms are needed desperately. Due to the extremely high frequency of KRAS gene mutations (>90%) detected in pancreatic cancer patients, the roles of the epidermal growth factor receptor (EGFR), Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTORC1/GSK-3 pathways have been investigated in pancreatic cancer for many years. Constitutively active Ras can activate both of these pathways and there is cross talk between Ras and EGFR which is believed to be important in driving metastasis. Mutant KRAS may also drive the expression of GSK-3 through Raf/MEK/ERK-mediated effects on GSK-3 transcription. GSK-3 can then regulate the expression of NF-kappaB which is important in modulating pancreatic cancer chemoresistance. While the receptors and many downstream signaling molecules have been identified and characterized, there is still much to learn about these pathways and how their deregulation can lead to cancer. Multiple inhibitors to EGFR, PI3K, mTOR, GSK-3, Raf, MEK and hedgehog (HH) have been developed and are being evaluated in various cancers. Current research often focuses on the role of these pathways in cancer stem cells (CSC), with the goal to identify sites where therapeutic resistance may develop. Relatively novel fields of investigation such as microRNAs and drugs used for other diseases e.g., diabetes, (metformin) and malaria (chloroquine) have provided new information about therapeutic resistance and CSCs. This review will focus on recent advances in the field and how they affect pancreatic cancer research and treatment.
Published: 2015

43. SARS-CoV-2 pathophysiology and its clinical implications: An integrative overview of the pharmacotherapeutic management of COVID-19

Author: Amar Bukhari, Diamantis P. Kofteridis, Vasileios Siokas, Leena Kavali, Giuseppe Lanza, Radu Mitrut, Sotirios G. Doukas, Dimitra P. Vageli, Michael Aschner, Monica Maria Bastos Paoliello, Demetrios A. Spandidos, Anca Oana Docea, Luca Falzone, Daniela Calina, Massimo Libra, Chiranjeevi Gadiparthi, Aristides M. Tsatsakis, Panagiotis G Doukas, Dimitrios Petrakis, and Manuela Pennisi
Subjects: Lung Diseases, Male, medicine.medical_specialty, ARDS, Clinical signs, Digestive System Diseases, COVID-19 pandemic, Neurological system, Comorbidity, Disease, Toxicology, Affect (psychology), Pulmonary system, Article, 03 medical and health sciences, 0404 agricultural biotechnology, Neoplasms, Epidemiology, medicine, Humans, SARS-C0V-2, Respiratory system, Intensive care medicine, Pandemics, Cancer, 030304 developmental biology, 0303 health sciences, SARS-CoV-2, business.industry, fungi, COVID-19, 04 agricultural and veterinary sciences, General Medicine, Gastrointestinal system, medicine.disease, 040401 food science, Pathophysiology, COVID-19 Drug Treatment, Cardiovascular system, Cardiovascular Diseases, Female, Kidney Diseases, Nervous System Diseases, business, Food Science
Abstract: Common manifestations of COVID-19 are respiratory and can extend from mild symptoms to severe acute respiratory distress. The severity of the illness can also extend from mild disease to life-threatening acute respiratory distress syndrome (ARDS). SARS-CoV-2 infection can also affect the gastrointestinal tract, liver and pancreatic functions, leading to gastrointestinal symptoms. Moreover, SARS-CoV-2 can cause central and peripheral neurological manifestations, affect the cardiovascular system and promote renal dysfunction. Epidemiological data have indicated that cancer patients are at a higher risk of contracting the SARS-CoV-2 virus. Considering the multitude of clinical symptoms of COVID-19, the objective of the present review was to summarize their pathophysiology in previously healthy patients, as well as in those with comorbidities. The present review summarizes the current, though admittedly fluid knowledge on the pathophysiology and symptoms of COVID-19 infection. Although unclear issues still remain, the present study contributes to a more complete understanding of the disease, and may drive the direction of new research. The recognition of the severity of the clinical symptoms of COVID-19 is crucial for the specific therapeutic management of affected patients., Graphical abstract Image 1, Highlights • Respiratory system is the main target of SARS-CoV-2. • SARS-CoV-2 infection can also affect the gastrointestinal tract, liver and pancreatic functions. • SARS-CoV-2 can cause central and peripheral neurological manifestations. • SARS-CoV-2 can affect the cardiovascular system and promote renal dysfunction. • Cancer patients are at a higher risk of contracting the SARS-CoV-2 virus.
Published: 2020

44. Self powered solar tracker for Low Concentration PV (LCPV) systems

Author: Vladislav Poulek, A. Khudysh, and M. Libra
Subjects: Renewable Energy, Sustainability and the Environment, business.industry, BitTorrent tracker, 020209 energy, Photovoltaic system, 02 engineering and technology, Tracking (particle physics), Automotive engineering, Power (physics), Solar tracker, Optics, Range (aeronautics), 0202 electrical engineering, electronic engineering, information engineering, Environmental science, General Materials Science, business, Volume concentration, Pv power
Abstract: A design and performance of a new self powered LCPV solar trackers using bifacial solar cells and a concentrating mirror is described in the report. This design does not need additional power supply nor cables and so it is cheaper than classical PV power plants with many cables. The power supply bifacial PV panels are simultaneously used as sun sensors. The new tracker design with bifacial solar cells was successfully used at big MW range PV power plants. The very simple self powered tracker with concentrating mirror was successfully tested at Low Concentration PV (LCPV) systems. The tracking accuracy is less than ±1 angular degree.
Published: 2016

45. Tumor microenvironment in diffuse large B-cell lymphoma: Matrixmetalloproteinases activation is mediated by osteopontin overexpression

Author: Paola Spessotto, James A. McCubrey, Silvana Canevari, Claudio Guarneri, Sameh Hafsi, Jerry Polesel, Giancarlo Castellano, Massimo Libra, Santo Signorelli, and Grazia Malaponte
Subjects: Male, 0301 basic medicine, Enzyme-Linked Immunosorbent Assay, Inflammation, B-cell lymphomas, Matrixmetalloproteinase, Peripheral blood mononuclear cell, Metastasis, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, Tumor Microenvironment, medicine, Humans, B-cell lymphomas, Interleukin-6, Matrixmetalloproteinase, Osteopontin, Cell Biology, Molecular Biology, Osteopontin, Cell adhesion, Molecular Biology, Cells, Cultured, Tumor microenvironment, biology, Interleukin-6, Cell Biology, Middle Aged, medicine.disease, Enzyme Activation, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Matrix Metalloproteinase 9, 030220 oncology & carcinogenesis, Multivariate Analysis, Cancer cell, Immunology, Leukocytes, Mononuclear, biology.protein, Matrix Metalloproteinase 2, Regression Analysis, Female, Lymphoma, Large B-Cell, Diffuse, medicine.symptom, Diffuse large B-cell lymphoma
Abstract: Non-Hodgkin lymphomas (NHL) are a heterogeneous group of lymphoproliferative malignancies with variable patterns of behavior and responses to therapy. NHL development and invasion depend on multiple interactions between tumor cells and non-neoplastic cells. Such interactions are usually modulated by several cytokines. Accordingly, it was demonstrated that matrix-metalloproteinase (MMP)-2 and MMP-9 were activated in human lymphoid cell lines by interleukin-6 (IL-6). The activation of these enzymes is associated with tumor invasion and metastasis in human cancers. MMPs are also activated in several cancers by osteopontin (OPN), a secreted glycoprotein that regulates cell adhesion, migration, and survival. However, it is still unclear if MMPs play a role in NHL development and if their activation is determined by OPN and/or IL-6. In the present study, two groups of 78 NHL patients and 95 healthy donors were recruited for the analysis of OPN, MMP-2, MMP-9 and IL-6.Significant higher circulating levels of MMP-2, MMP-9, OPN and IL-6 were observed in NHL patients when compared to healthy donors. Similar data were obtained by analyzing the activity of both MMP-2 and MMP-9. The multivariate regression model indicates that, in both NHL cases and healthy donors, OPN is associated with the increase of MMP-2 and MMP-9 levels independently of IL-6. These data were first confirmed by “in silico” analyses and then by “in vitro” experiments conducted on peripheral blood mononuclear cells randomly selected from both NHL patients and healthy donors.Overall, our data suggest that the activation of MMPs in NHL development is mostly associated with OPN. However, IL-6 may play an important role in the lymphomagenesis through the activation of other molecular pathways. This article is part of a Special Issue entitled: Tumor Microenvironment Regulation of Cancer Cell Survival, Metastasis, Inflammation, and Immune Surveillance edited by Peter Ruvolo and Gregg L. Semenza.
Published: 2016

46. Sorption of four hydrophobic organic contaminants by biochars derived from maize straw, wood dust and swine manure at different pyrolytic temperatures

Author: Ke Sun, Judy A. Libra, Baoshan Xing, Lanfang Han, Xitao Liu, Kyoung S. Ro, Ziying Wang, and Jie Jin
Subjects: Hot Temperature, Environmental Engineering, 010504 meteorology & atmospheric sciences, Surface Properties, Swine, Health, Toxicology and Mutagenesis, 010501 environmental sciences, Zea mays, 01 natural sciences, chemistry.chemical_compound, Adsorption, Biochar, Animals, Environmental Chemistry, Organic chemistry, Acetochlor, Organic Chemicals, Charcoal, 0105 earth and related environmental sciences, Chemistry, Temperature, Public Health, Environmental and Occupational Health, Dust, Sorption, General Medicine, General Chemistry, Phenanthrenes, Phenanthrene, Straw, Wood, Pollution, Manure, Dibutyl Phthalate, Environmental chemistry, visual_art, visual_art.visual_art_medium, Environmental Pollutants, Hydrophobic and Hydrophilic Interactions
Abstract: Sorption behavior of acetochlor (ACE), dibutyl phthalate (DBP), 17α-Ethynyl estradiol (EE2) and phenanthrene (PHE) with biochars produced from three feedstocks (maize straw (MABs), pine wood dust (WDBs) and swine manure (SWBs)) at seven heat treatment temperatures (HTTs) was evaluated. The bulk polarity of these biochars declined with increasing HTT while the aromaticity and CO2-surface area (CO2-SA) rose. The surface OC contents of biochars were generally higher than bulk OC contents. The organic carbon (OC)-normalized CO2-SA (CO2-SA/OC) of biochars significantly correlated with the sorption coefficients (n and logK(oc)), suggesting that pore filling could dominate the sorption of tested sorbates. SWBs had higher logK(oc) values compared to MABs and WDBs, due to their higher ash contents. Additionally, the logK(oc) values for MABs was relatively greater than that for WDBs at low HTTs (≤400 °C), probably resulting from the higher CO2-SA/OC, ash contents and aromaticity of MABs. Surface polarity and the aliphatic C may dominate the sorption of WDBs obtained at relatively low HTTs (≤400 °C), while aromatic C affects the sorption of biochars at high HTTs. Results of this work aid to deepen our understanding of the sorption mechanisms, which is pivotal to wise utilization of biochars as sorbents for hazardous organic compounds.
Published: 2016

47. Leachate water quality of soils amended with different swine manure-based amendments

Author: Ariel A. Szogi, Mark Johnson, Kurt A. Spokas, Kyoung S. Ro, Jeffrey M. Novak, Sunyoung Bae, and Judy A. Libra
Subjects: Manure management, Environmental Engineering, Swine, Health, Toxicology and Mutagenesis, 010501 environmental sciences, 01 natural sciences, Soil, Water Quality, Cation-exchange capacity, Animals, Environmental Chemistry, Recycling, Leaching (agriculture), 0105 earth and related environmental sciences, Soil organic matter, Public Health, Environmental and Occupational Health, 04 agricultural and veterinary sciences, General Medicine, General Chemistry, Pollution, Manure, Soil conditioner, Agronomy, Environmental chemistry, Soil water, 040103 agronomy & agriculture, 0401 agriculture, forestry, and fisheries, Environmental science, Adsorption, Soil fertility, Water Pollutants, Chemical
Abstract: In the face of the rising level of manure production from concentrated animal feeding operations (CAFOs), management options are being sought that can provide nutrient recycling for plant growth and improved soil conditions with minimal environmental impacts. Alternatives to direct manure application are composting and thermochemical conversion which can destroy pathogens and improve handling and storage. The effect of four forms of swine manure-based soil amendments (raw, compost, hydrochar, and pyrochar) on soil fertility and leachate water quality characteristics of a sandy soil were investigated in soil incubation experiments. All four amendments significantly increased soil carbon, cation exchange capacity and available nutrient contents of the soil. However, hydrochar amended soil leached lower amounts of N, P, and K compared to the other amendments including the control. On the other hand, pyrochar amended soil leached higher concentrations of P and K. Subsequent tests on the hydrochar for K and N adsorption isotherms and surface analysis via XPS suggested that these nutrients were not sorbed directly to the hydrochar surface. Although it is still not clear how these nutrients were retained in the soil amended with hydrochar, it suggests a great potential for hydrochar as an alternative manure management option as the hydrochar can be soil applied while minimizing potential environmental issues from the leaching of high nutrient concentrations to water bodies.
Published: 2016

48. Variation in sorption of propiconazole with biochars: The effect of temperature, mineral, molecular structure, and nano-porosity

Author: Baoshan Xing, Ye Zhao, Judy A. Libra, Kyoung S. Ro, Mingjie Kang, and Ke Sun
Subjects: Environmental Engineering, Health, Toxicology and Mutagenesis, 010501 environmental sciences, 01 natural sciences, Nanopores, Adsorption, Biochar, Animals, Environmental Chemistry, Organic matter, Porosity, Charcoal, 0105 earth and related environmental sciences, chemistry.chemical_classification, Total organic carbon, Minerals, Temperature, Public Health, Environmental and Occupational Health, Sorption, 04 agricultural and veterinary sciences, General Medicine, General Chemistry, Triazoles, Pollution, chemistry, Environmental chemistry, visual_art, 040103 agronomy & agriculture, visual_art.visual_art_medium, 0401 agriculture, forestry, and fisheries, Environmental Pollutants, Water treatment
Abstract: Sorption behavior of propiconazole (PROPI) by plant-residue derived biochars (PLABs) and animal waste-derived biochars (ANIBs) obtained at three heating treatment temperatures (HTTs) (300, 450 and 600 °C) (e.g., BCs300, BCs450, and BCs600) and their corresponding de-ashed BCs450 was investigated. PLABs belonged to high- or medium-C biochars and ANIBs were low-C biochars. Surface C concentrations of the tested biochars were generally higher than their corresponding bulk C. Surface polar groups were mainly composed of O-containing groups of minerals within biochars. The nonlinearity coefficients (n) of propiconazole (PROPI) sorption isotherms ranged from 0.23 to 0.64, which was significantly and negatively related to organic carbon (OC)-normalized CO2-surface area (CO2-SA/OC) of biochars. This correlation along with the positive relationship between CO2-SA/OC and aromaticity indicates that pore-filling in nanopores within aromatic C dominate nonlinear PROPI sorption. HTTs or C contents do not necessarily regulate PROPI sorption. Removal of minerals from BCs450 elevated PROPI sorption because minerals may exert certain influence on sorption via impacting spatial arrangement of polar groups and/or organic matter (OM)-mineral interactions. This study helps to better understand sorption behavior of PROPI to biochars and evaluate the potential role of biochar in water treatment systems.
Published: 2016

49. Effect of a low glycemic index Mediterranean diet on cardiovascular risk factors in women diagnosed with breast cancer: Preliminary data from DEDiCa study

Author: Calabrese, Ilaria, primary, Porciello, Giuseppe, additional, Montagnese, Concetta, additional, Vitale, Sara, additional, Palumbo, Elvira, additional, Cubisino, Serena, additional, Crispo, Anna, additional, Grimaldi, Maria, additional, Pica, Rosita, additional, Marotta, Vincenzo, additional, Falzone, Luca, additional, Dainotta, Patrizia, additional, De Laurentis, Michele, additional, D'Aiuto, Massimiliano, additional, Rinaldo, Massimo, additional, Thomas, Guglielmo, additional, Catalano, Francesca, additional, Banna, Giuseppe, additional, Ursino, Vera, additional, Ferraù, Francesco, additional, Rossello, Rosalba, additional, Serraino, Diego, additional, Bidoli, Ettore, additional, Massarut, Samuele, additional, Barchiesi, Vittoria, additional, Minopoli, Anita, additional, Cuomo, Marco, additional, Cavalcanti, Ernesta, additional, Cianniello, Daniela, additional, Pacilio, Carmen, additional, Guerra, Gennaro, additional, Farina, Amalia, additional, Messina, Francesco, additional, Pinto, Monica, additional, Poletto, Luigina, additional, Cervo, Silvia, additional, D'Andrea, Monica, additional, Steffan, Agostino, additional, Riccardi, Gabriele, additional, Jenkins, David J A, additional, Gatti, Davide, additional, Libra, Massimo, additional, Montella, Maurizio, additional, and Augustin, Livia S A, additional
Published: 2019
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50. Abilities of berberine and chemically modified berberines to interact with metformin and inhibit proliferation of pancreatic cancer cells

Author: Akula, Shaw M., primary, Candido, Saverio, additional, Libra, Massimo, additional, Abrams, Stephen L., additional, Steelman, Linda S., additional, Lertpiriyapong, Kvin, additional, Ramazzotti, Giulia, additional, Ratti, Stefano, additional, Follo, Matilde Y., additional, Martelli, Alberto M., additional, Murata, Ramiro M., additional, Rosalen, Pedro L., additional, Bueno-Silva, Bruno, additional, Matias de Alencar, Severino, additional, Montalto, Giuseppe, additional, Cervello, Melchiorre, additional, Gizak, Agnieszka, additional, Rakus, Dariusz, additional, Mao, Weifeng, additional, Lin, Heng-Liang, additional, Lombardi, Paolo, additional, and McCubrey, James A., additional
Published: 2019
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