74 results on '"Leggio, Lorenzo"'
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2. Pharmacological GHSR (ghrelin receptor) blockade reduces alcohol binge-like drinking in male and female mice
3. Role of aldosterone and mineralocorticoid receptor (MR) in addiction: a scoping review
4. T102. IDENTIFYING NEW TREATMENT TARGETS FOR ALCOHOL USE DISORDER THROUGH GENETIC AND ELECTRONIC HEALTH RECORDS DATA APPROACHES
5. Converging Evidence from Rodent and Human Studies on the Role of Spironolactone as a Potential Pharmacotherapy for Alcohol Use Disorder
6. 66. Pre-Clinical Insights: Ghrelin Receptor Blockade Reduces Binge-Like Alcohol Drinking in Male and Female Mice
7. A human laboratory study on the link between alcohol administration and circulating fibroblast growth factor 21 (FGF21) in individuals with alcohol use disorder
8. Changes in plasma ghrelin levels following surgical and non-surgical weight-loss in female rats predict alcohol use
9. Echocardiographic markers of early alcoholic cardiomyopathy: Six-month longitudinal study in heavy drinking patients
10. The Amygdala Noradrenergic System Is Compromised With Alcohol Use Disorder
11. FGF21 regulates alcohol intake: New hopes on the rise for alcohol use disorder treatment?
12. Barriers to the management of alcohol use disorder and alcohol-associated liver disease: strategies to implement integrated care models
13. Alcohol-medication interactions: A systematic review and meta-analysis of placebo-controlled trials
14. Synthesis of PF-6870961, a major hydroxy metabolite of the novel ghrelin receptor inverse agonist PF-5190457
15. A population-based investigation of the association between alcohol intake and serum total ghrelin concentrations among cigarette-smoking, non-alcohol-dependent male individuals
16. Effect of oral alcohol administration on plasma cytokine concentrations in heavy drinking individuals
17. The influence of anxiety symptoms on clinical outcomes during baclofen treatment of alcohol use disorder: A systematic review and meta-analysis
18. Sensory cue reactivity: Sensitization in alcohol use disorder and obesity
19. A neuroimaging investigation into the role of peripheral metabolic biomarkers in the anticipation of reward in alcohol use
20. Interventions and Manipulations of Interoception
21. Investigating the link between serum concentrations of brain-derived neurotrophic factor and behavioral measures in anxious alcohol-dependent individuals
22. Leveraging genetic data to investigate molecular targets and drug repurposing candidates for treating alcohol use disorder and hepatotoxicity
23. Effects of exogenous ghrelin administration and ghrelin receptor blockade, in combination with alcohol, on peripheral inflammatory markers in heavy-drinking individuals: Results from two human laboratory studies
24. Endocrine effects of the novel ghrelin receptor inverse agonist PF-5190457: Results from a placebo-controlled human laboratory alcohol co-administration study in heavy drinkers
25. Peripheral proinflammatory markers are upregulated in abstinent alcohol-dependent patients but are not affected by cognitive bias modification: Preliminary findings
26. Development and validation of an assay for a novel ghrelin receptor inverse agonist PF-5190457 and its major hydroxy metabolite (PF-6870961) by LC-MS/MS in human plasma
27. Intravenous administration of ghrelin increases serum cortisol and aldosterone concentrations in heavy-drinking alcohol-dependent individuals: Results from a double-blind, placebo-controlled human laboratory study
28. Sex differences in the response to opioids for pain relief: A systematic review and meta-analysis
29. HIV and alcohol use disorder: we cannot ignore the elephant in the room
30. Using Machine Learning to Classify Individuals With Alcohol Use Disorder Based on Treatment Seeking Status
31. Ghrelin: From a gut hormone to a potential therapeutic target for alcohol use disorder
32. Reduced plasma ghrelin concentrations are associated with decreased brain reactivity to food cues after laparoscopic sleeve gastrectomy
33. Using Machine Learning to Classify Individuals with Alcohol Use Disorder Based on Treatment Seeking Status
34. Long-Term Outcome of Repetitive Transcranial Magnetic Stimulation in a Large Cohort of Patients with Cocaine-Use Disorder: An Observational Study
35. Baclofen and alcohol in France – Authors' reply
36. Baclofen for the treatment of alcohol use disorder: the Cagliari Statement
37. Repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex may improve symptoms of anhedonia in individuals with cocaine use disorder: A pilot study
38. Pharmacological manipulation of the ghrelin system and alcohol hangover symptoms in heavy drinking individuals: Is there a link?
39. Neuroendocrine response to GABA-B receptor agonism in alcohol-dependent individuals: Results from a combined outpatient and human laboratory experiment
40. Dataset for Phase I randomized clinical trial for safety and tolerability of GET 73 in single and repeated ascending doses including preliminary pharmacokinetic parameters
41. Relationship between craving and plasma leptin concentrations in patients with cocaine addiction
42. Effect of alcohol use disorder on oxytocin peptide and receptor mRNA expression in human brain: A post-mortem case-control study
43. A Phase I randomized clinical trial testing the safety, tolerability and preliminary pharmacokinetics of the mGluR5 negative allosteric modulator GET 73 following single and repeated doses in healthy volunteers
44. Acute effects of intravenous cocaine administration on serum concentrations of ghrelin, amylin, glucagon-like peptide-1, insulin, leptin and peptide YY and relationships with cardiorespiratory and subjective responses
45. Higher pretreatment blood pressure is associated with greater alcohol drinking reduction in alcohol-dependent individuals treated with doxazosin
46. A chimeric approach to evaluate the role of corticotropin releasing factor in alcohol use disorder
47. Ghrelin as potential new pathway toward medication development for alcohol use disorder: Recent clinical data
48. GABBR2 gene variants affect cigarette smoking pattern in alcohol-dependent individuals: A genetic association study
49. Treatment of Alcohol Use Disorder in Patients with Alcoholic Liver Disease
50. Modulating Morphine Context-Induced Drug Memory With Deep Brain Stimulation: More Research Questions by Lowering Stimulation Frequencies?
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