66 results on '"Kulkarni, Rohit N."'
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2. Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
3. Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD
4. ROCK1 regulates insulin secretion from β-cells
5. E2F1 transcription factor mediates a link between fat and islets to promote β cell proliferation in response to acute insulin resistance
6. In vivo drug discovery for increasing incretin-expressing cells identifies DYRK inhibitors that reinforce the enteroendocrine system
7. Uncoupling protein 2 and aldolase B impact insulin release by modulating mitochondrial function and Ca2+ release from the ER
8. IL18 signaling causes islet β cell development and insulin secretion via different receptors on acinar and β cells
9. Insulin regulates arginine-stimulated insulin secretion in humans
10. Essential roles of insulin and IGF-1 receptors during embryonic lineage development
11. Insulin receptor substrate 1, but not IRS2, plays a dominant role in regulating pancreatic alpha cell function in mice
12. Defective insulin receptor signaling in hPSCs skews pluripotency and negatively perturbs neural differentiation
13. Epigenetics in β-cell adaptation and type 2 diabetes
14. RNA-Binding Protein HuD Controls Insulin Translation
15. Leptin Receptor Signaling Regulates Protein Synthesis Pathways and Neuronal Differentiation in Pluripotent Stem Cells
16. Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention
17. “Omics” and “epi-omics” underlying the β-cell adaptation to insulin resistance
18. HNF4A Haploinsufficiency in MODY1 Abrogates Liver and Pancreas Differentiation from Patient-Derived Induced Pluripotent Stem Cells
19. Forkhead box protein O1 (FoxO1) regulates hepatic serine protease inhibitor B1 (serpinB1) expression in a non-cell-autonomous fashion
20. Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation
21. Sex differences underlying pancreatic islet biology and its dysfunction
22. Signaling between pancreatic β cells and macrophages via S100 calcium-binding protein A8 exacerbates β-cell apoptosis and islet inflammation
23. The role of the carboxyl ester lipase (CEL) gene in pancreatic disease
24. Nuclear import of glucokinase in pancreatic beta-cells is mediated by a nuclear localization signal and modulated by SUMOylation
25. Isoform-selective inhibitor of histone deacetylase 3 (HDAC3) limits pancreatic islet infiltration and protects female nonobese diabetic mice from diabetes
26. Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation
27. Adipocyte Dynamics and Reversible Metabolic Syndrome in Mice with an Inducible Adipocyte-Specific Deletion of the Insulin Receptor
28. Nuclear Export of FoxO1 Is Associated with ERK Signaling in β-Cells Lacking Insulin Receptors
29. ERRγ—A New Player in β Cell Maturation
30. Proinflammatory Cytokines Induce Endocrine Differentiation in Pancreatic Ductal Cells via STAT3-Dependent NGN3 Activation
31. Early Developmental Perturbations in a Human Stem Cell Model of MODY5/HNF1B Pancreatic Hypoplasia
32. Increased Glucose-induced Secretion of Glucagon-like Peptide-1 in Mice Lacking the Carcinoembryonic Antigen-related Cell Adhesion Molecule 2 (CEACAM2)
33. SerpinB1 Promotes Pancreatic β Cell Proliferation
34. Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools
35. Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes
36. High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice
37. Epigenetic modifiers of islet function and mass
38. The Polycomb protein, Bmi1, regulates insulin sensitivity
39. Comparable Generation of Activin-Induced Definitive Endoderm via Additive Wnt or BMP Signaling in Absence of Serum
40. GCK-MODY diabetes as a protein misfolding disease: The mutation R275C promotes protein misfolding, self-association and cellular degradation
41. New Opportunities: Harnessing Induced Pluripotency for Discovery in Diabetes and Metabolism
42. Quantitative site-specific reactivity profiling of S-nitrosylation in mouse skeletal muscle using cysteinyl peptide enrichment coupled with mass spectrometry
43. Liver-Derived Systemic Factors Drive β Cell Hyperplasia in Insulin-Resistant States
44. SUMOylation of Pancreatic Glucokinase Regulates Its Cellular Stability and Activity*
45. Derivation of Human Induced Pluripotent Stem Cells from Patients with Maturity Onset Diabetes of the Young*
46. GCK-MODY diabetes associated with protein misfolding, cellular self-association and degradation
47. RNA-Binding Protein HuD Controls Insulin Translation
48. Loss of Glucagon-Like Peptide-2–Induced Proliferation Following Intestinal Epithelial Insulin-Like Growth Factor-1–Receptor Deletion
49. Class IA Phosphatidylinositol 3-Kinase in Pancreatic β Cells Controls Insulin Secretion by Multiple Mechanisms
50. Pancreatic Function in Carboxyl-Ester Lipase Knockout Mice
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