341 results on '"Kremen A"'
Search Results
2. “We followed their lead”: Exploring relational change and support among caregivers of transgender and gender diverse youth
- Author
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Tarantino, Mari R., primary, Tham, Regina L., additional, Quint, Meg R., additional, Kremen, Jessica, additional, Kane, Kaiden, additional, Rangel-Gomez, Mauricio, additional, Boskey, Elizabeth, additional, Xu, Rena, additional, and Reisner, Sari L., additional
- Published
- 2024
- Full Text
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3. Atypical brain aging and its association with working memory performance in major depressive disorder
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Ho, Natalie C.W., primary, Bethlehem, Richard AI., additional, Seidlitz, Jakob, additional, Nogovitsyn, Nikita, additional, Metzak, Paul, additional, Ballester, Pedro L., additional, Hassel, Stefanie, additional, Rotzinger, Susan, additional, Poppenk, Jordan, additional, Lam, Raymond W., additional, Taylor, Valerie H., additional, Milev, Roumen, additional, Adamson, Chris, additional, Adler, Sophie, additional, Alexander-Bloch, Aaron F., additional, Anagnostou, Evdokia, additional, Anderson, Kevin M., additional, Areces-Gonzalez, Ariosky, additional, Astle, Duncan E., additional, Auyeung, Bonnie, additional, Ayub, Muhammad, additional, Bae, Jong Bin, additional, Ball, Gareth, additional, Baron-Cohen, Simon, additional, Beare, Richard, additional, Bedford, Saashi A., additional, Benegal, Vivek, additional, Bethlehem, Richard A.I., additional, Beyer, Frauke, additional, Blangero, John, additional, Blesa Cábez, Manuel, additional, Boardman, James P., additional, Borzage, Matthew, additional, Bosch-Bayard, Jorge F., additional, Bourke, Niall, additional, Bullmore, Edward T., additional, Calhoun, Vince D., additional, Chakravarty, Mallar M., additional, Chen, Christina, additional, Chertavian, Casey, additional, Chetelat, Gaël, additional, Chong, Yap S., additional, Corvin, Aiden, additional, Costantino, Manuela, additional, Courchesne, Eric, additional, Crivello, Fabrice, additional, Cropley, Vanessa L., additional, Crosbie, Jennifer, additional, Crossley, Nicolas, additional, Delarue, Marion, additional, Delorme, Richard, additional, Desrivieres, Sylvane, additional, Devenyi, Gabriel, additional, Di Biase, Maria A., additional, Dolan, Ray, additional, Donald, Kirsten A., additional, Donohoe, Gary, additional, Dorfschmidt, Lena, additional, Dunlop, Katharine, additional, Edwards, Anthony D., additional, Elison, Jed T., additional, Ellis, Cameron T., additional, Elman, Jeremy A., additional, Eyler, Lisa, additional, Fair, Damien A., additional, Fletcher, Paul C., additional, Fonagy, Peter, additional, Franz, Carol E., additional, Galan-Garcia, Lidice, additional, Gholipour, Ali, additional, Giedd, Jay, additional, Gilmore, John H., additional, Glahn, David C., additional, Goodyer, Ian M., additional, Grant, P.E., additional, Groenewold, Nynke A., additional, Gudapati, Shreya, additional, Gunning, Faith M., additional, Gur, Raquel E., additional, Gur, Ruben C., additional, Hammill, Christopher F., additional, Hansson, Oskar, additional, Hedden, Trey, additional, Heinz, Andreas, additional, Henson, Richard N., additional, Heuer, Katja, additional, Hoare, Jacqueline, additional, Holla, Bharath, additional, Holmes, Avram J., additional, Huang, Hao, additional, Ipser, Jonathan, additional, Jack, Clifford R., additional, Jackowski, Andrea P., additional, Jia, Tianye, additional, Jones, David T., additional, Jones, Peter B., additional, Kahn, Rene S., additional, Karlsson, Hasse, additional, Karlsson, Linnea, additional, Kawashima, Ryuta, additional, Kelley, Elizabeth A., additional, Kern, Silke, additional, Kim, Ki-Woong, additional, Kitzbichler, Manfred G., additional, Kremen, William S., additional, Lalonde, François, additional, Landeau, Brigitte, additional, Lerch, Jason, additional, Lewis, John D., additional, Li, Jiao, additional, Liao, Wei, additional, Liston, Conor, additional, Lombardo, Michael V., additional, Lv, Jinglei, additional, Mallard, Travis T., additional, Marcelis, Machteld, additional, Mathias, Samuel R., additional, Mazoyer, Bernard, additional, McGuire, Philip, additional, Meaney, Michael J., additional, Mechelli, Andrea, additional, Misic, Bratislav, additional, Morgan, Sarah E., additional, Mothersill, David, additional, Ortinau, Cynthia, additional, Ossenkoppele, Rik, additional, Ouyang, Minhui, additional, Palaniyappan, Lena, additional, Paly, Leo, additional, Pan, Pedro M., additional, Pantelis, Christos, additional, Park, Min Tae M., additional, Paus, Tomas, additional, Pausova, Zdenka, additional, Paz-Linares, Deirel, additional, Pichet Binette, Alexa, additional, Pierce, Karen, additional, Qian, Xing, additional, Qiu, Anqi, additional, Raznahan, Armin, additional, Rittman, Timothy, additional, Rodrigue, Amanda, additional, Rollins, Caitlin K., additional, Romero-Garcia, Rafael, additional, Ronan, Lisa, additional, Rosenberg, Monica D., additional, Rowitch, David H., additional, Salum, Giovanni A., additional, Satterthwaite, Theodore D., additional, Schaare, H. Lina, additional, Schabdach, Jenna, additional, Schachar, Russell J., additional, Schöll, Michael, additional, Schultz, Aaron P., additional, Sharp, David, additional, Shinohara, Russell T., additional, Skoog, Ingmar, additional, Smyser, Christopher D., additional, Sperling, Reisa A., additional, Stein, Dan J., additional, Stolicyn, Aleks, additional, Suckling, John, additional, Sullivan, Gemma, additional, Thyreau, Benjamin, additional, Toro, Roberto, additional, Traut, Nicolas, additional, Tsvetanov, Kamen A., additional, Turk-Browne, Nicholas B., additional, Tuulari, Jetro J., additional, Tzourio, Christophe, additional, Vachon-Presseau, Étienne, additional, Valdes-Sosa, Mitchell J., additional, Valdes-Sosa, Pedro A., additional, Valk, Sofie L., additional, van Amelsvoort, Therese, additional, Vandekar, Simon N., additional, Vasung, Lana, additional, Vértes, Petra E., additional, Victoria, Lindsay W., additional, Villeneuve, Sylvia, additional, Villringer, Arno, additional, Vogel, Jacob W., additional, Wagstyl, Konrad, additional, Wang, Yin-Shan S., additional, Warfield, Simon K., additional, Warrier, Varun, additional, Westman, Eric, additional, Westwater, Margaret L., additional, Whalley, Heather C., additional, White, Simon R., additional, Witte, A. Veronica, additional, Yang, Ning, additional, Yeo, B.T. Thomas, additional, Yun, Hyuk Jin, additional, Zalesky, Andrew, additional, Zar, Heather J., additional, Zettergren, Anna, additional, Zhou, Juan H., additional, Ziauddeen, Hisham, additional, Zimmerman, Dabriel, additional, Zugman, Andre, additional, Zuo, Xi-Nian N., additional, Frey, Benicio N., additional, Harkness, Kate L., additional, Addington, Jean, additional, and Kennedy, Sidney H., additional
- Published
- 2024
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4. Multisite Chronic Pain Accelerates Cognitive Decline Particularly in Apolipoprotein E E4 Allele Carriers
- Author
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Bell, Tyler R., primary, Franz, Carol E., additional, Lerman, Imanuel, additional, Fennema-Notestine, Christine, additional, Williams, McKenna E., additional, Panizzon, Matthew S., additional, Elman, Jeremy A., additional, Reynolds, Chandra A., additional, and Kremen, William S., additional
- Published
- 2024
- Full Text
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5. Reverse Total Shoulder Arthroplasty with Proximal Bone Loss: A Biomechanical Comparison of Partially versus Fully Cemented Humeral Stems
- Author
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Maturana, Carlos, primary, Peterson, Brandon, additional, Shi, Brendan, additional, Mooney, Bailey, additional, Clites, Tyler, additional, and Kremen, Thomas J., additional
- Published
- 2024
- Full Text
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6. Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data
- Author
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Jo, Taeho, primary, Kim, Junpyo, additional, Bice, Paula, additional, Huynh, Kevin, additional, Wang, Tingting, additional, Arnold, Matthias, additional, Meikle, Peter J., additional, Giles, Corey, additional, Kaddurah-Daouk, Rima, additional, Saykin, Andrew J., additional, Nho, Kwangsik, additional, Kueider-Paisley, Alexandra, additional, Doraiswamy, P. Murali, additional, Blach, Colette, additional, Moseley, Arthur, additional, Thompson, Will, additional, St John-Williams, Lisa, additional, Mahmoudiandehkhordi, Siamak, additional, Tenenbaum, Jessica, additional, Welsh-Balmer, Kathleen, additional, Plassman, Brenda, additional, Risacher, Shannon L., additional, Kastenmüller, Gabi, additional, Han, Xianlin, additional, Baillie, Rebecca, additional, Knight, Rob, additional, Dorrestein, Pieter, additional, Brewer, James, additional, Mayer, Emeran, additional, Labus, Jennifer, additional, Baldi, Pierre, additional, Gupta, Arpana, additional, Fiehn, Oliver, additional, Barupal, Dinesh, additional, Meikle, Peter, additional, Mazmanian, Sarkis, additional, Rader, Dan, additional, Kling, Mitchel, additional, Shaw, Leslie, additional, Trojanowski, John, additional, van Duijin, Cornelia, additional, Nevado-Holgado, Alejo, additional, Bennett, David, additional, Krishnan, Ranga, additional, Keshavarzian, Ali, additional, Vogt, Robin, additional, Ikram, Arfan, additional, Hankemeier, Thomas, additional, Thiele, Ines, additional, Price, Nathan, additional, Funk, Cory, additional, Baloni, Priyanka, additional, Jia, Wei, additional, Wishart, David, additional, Brinton, Roberta, additional, Chang, Rui, additional, Farrer, Lindsay, additional, Au, Rhoda, additional, Qiu, Wendy, additional, Würtz, Peter, additional, Koal, Therese, additional, Mangravite, Lara, additional, Krumsiek, Jan, additional, Suhre, Karsten, additional, Newman, John, additional, Moreno, Herman, additional, Foroud, Tatania, additional, Sacks, Frank, additional, Jansson, Janet, additional, Weiner, Michael W., additional, Aisen, Paul, additional, Petersen, Ronald, additional, Jack, Clifford R., additional, Jagust, William, additional, Trojanowki, John Q., additional, Toga, Arthur W., additional, Beckett, Laurel, additional, Green, Robert C., additional, Morris, John C., additional, Perrin, Richard J., additional, Shaw, Leslie M., additional, Khachaturian, Zaven, additional, Carrillo, Maria, additional, Potter, William, additional, Barnes, Lisa, additional, Bernard, Marie, additional, Gonzalez, Hector, additional, Ho, Carole, additional, Hsiao, John K., additional, Jackson, Jonathan, additional, Masliah, Eliezer, additional, Masterman, Donna, additional, Okonkwo, Ozioma, additional, Perrin, Richard, additional, Ryan, Laurie, additional, Silverberg, Nina, additional, Fleisher, Adam, additional, Sacrey, Diana Truran, additional, Fockler, Juliet, additional, Conti, Cat, additional, Veitch, Dallas, additional, Neuhaus, John, additional, Jin, Chengshi, additional, Nosheny, Rachel, additional, Ashford, Miriam, additional, Flenniken, Derek, additional, Kormos, Adrienne, additional, Montine, Tom, additional, Rafii, Michael, additional, Raman, Rema, additional, Jimenez, Gustavo, additional, Donohue, Michael, additional, Gessert, Devon, additional, Salazar, Jennifer, additional, Zimmerman, Caileigh, additional, Cabrera, Yuliana, additional, Walter, Sarah, additional, Miller, Garrett, additional, Coker, Godfrey, additional, Clanton, Taylor, additional, Hergesheimer, Lindsey, additional, Smith, Stephanie, additional, Adegoke, Olusegun, additional, Mahboubi, Payam, additional, Moore, Shelley, additional, Pizzola, Jeremy, additional, Shaffer, Elizabeth, additional, Sloan, Brittany, additional, Harvey, Danielle, additional, Forghanian-Arani, Arvin, additional, Borowski, Bret, additional, Ward, Chad, additional, Schwarz, Christopher, additional, Jones, David, additional, Gunter, Jeff, additional, Kantarci, Kejal, additional, Senjem, Matthew, additional, Vemuri, Prashanthi, additional, Reid, Robert, additional, Fox, Nick C., additional, Malone, Ian, additional, Thompson, Paul, additional, Thomopoulos, Sophia I., additional, Nir, Talia M., additional, Jahanshad, Neda, additional, DeCarli, Charles, additional, Knaack, Alexander, additional, Fletcher, Evan, additional, Tosun-Turgut, Duygu, additional, Chen, Stephanie Rossi, additional, Choe, Mark, additional, Crawford, Karen, additional, Yushkevich, Paul A., additional, Das, Sandhitsu, additional, Koeppe, Robert A., additional, Reiman, Eric M., additional, Chen, Kewei, additional, Mathis, Chet, additional, Landau, Susan, additional, Cairns, Nigel J., additional, Householder, Erin, additional, Franklin, Erin, additional, Bernhardt, Haley, additional, Taylor-Reinwald, Lisa, additional, Korecka, Magdalena, additional, Figurski, Michal, additional, Neu, Scott, additional, Apostolova, Liana G., additional, Shen, Li, additional, Foroud, Tatiana M., additional, Nudelman, Kelly, additional, Faber, Kelley, additional, Wilmes, Kristi, additional, Thal, Leon, additional, Silbert, Lisa C., additional, Lind, Betty, additional, Crissey, Rachel, additional, Kaye, Jeffrey A., additional, Carter, Raina, additional, Dolen, Sara, additional, Quinn, Joseph, additional, Schneider, Lon S., additional, Pawluczyk, Sonia, additional, Becerra, Mauricio, additional, Teodoro, Liberty, additional, Dagerman, Karen, additional, Spann, Bryan M., additional, Vanderswag, Helen, additional, Ziolkowski, Jaimie, additional, Heidebrink, Judith L., additional, Zbizek-Nulph, Lisa, additional, Lord, Joanne L., additional, Mason, Sara S., additional, Albers, Colleen S., additional, Knopman, David, additional, Johnson, Kris, additional, Villanueva-Meyer, Javier, additional, Pavlik, Valory, additional, Pacini, Nathaniel, additional, Lamb, Ashley, additional, Kass, Joseph S., additional, Doody, Rachelle S., additional, Shibley, Victoria, additional, Chowdhury, Munir, additional, Rountree, Susan, additional, Dang, Mimi, additional, Stern, Yaakov, additional, Honig, Lawrence S., additional, Mintz, Akiva, additional, Ances, Beau, additional, Winkfield, David, additional, Carroll, Maria, additional, Stobbs-Cucchi, Georgia, additional, Oliver, Angela, additional, Creech, Mary L., additional, Mintun, Mark A., additional, Schneider, Stacy, additional, Geldmacher, David, additional, Love, Marissa Natelson, additional, Griffith, Randall, additional, Clark, David, additional, Brockington, John, additional, Marson, Daniel, additional, Grossman, Hillel, additional, Goldstein, Martin A., additional, Greenberg, Jonathan, additional, Mitsis, Effie, additional, Shah, Raj C., additional, Lamar, Melissa, additional, Samuels, Patricia, additional, Duara, Ranjan, additional, Greig-Custo, Maria T., additional, Rodriguez, Rosemarie, additional, Albert, Marilyn, additional, Onyike, Chiadi, additional, Farrington, Leonie, additional, Rudow, Scott, additional, Brichko, Rottislav, additional, Kielb, Stephanie, additional, Smith, Amanda, additional, Raj, Balebail Ashok, additional, Fargher, Kristin, additional, Sadowski, Martin, additional, Wisniewski, Thomas, additional, Shulman, Melanie, additional, Faustin, Arline, additional, Rao, Julia, additional, Castro, Karen M., additional, Ulysse, Anaztasia, additional, Chen, Shannon, additional, Sheikh, Mohammed O., additional, Singleton-Garvin, Jamika, additional, Petrella, JeffreyR., additional, James, Olga, additional, Wong, Terence Z., additional, Borges-Neto, Salvador, additional, Karlawish, Jason H., additional, Wolk, David A., additional, Vaishnavi, Sanjeev, additional, Clark, Christopher M., additional, Arnold, Steven E., additional, Smith, Charles D., additional, Jicha, Gregory A., additional, Raslau, Flavius D., additional, Lopez, Oscar L., additional, Oakley, MaryAnn, additional, Simpson, Donna M., additional, Porsteinsson, Anton P., additional, Martin, Kim, additional, Kowalski, Nancy, additional, Keltz, Melanie, additional, Goldstein, Bonnie S., additional, Makino, Kelly M., additional, Ismail, M. Saleem, additional, Brand, Connie, additional, Thai, Gaby, additional, Pierce, Aimee, additional, Yanez, Beatriz, additional, Sosa, Elizabeth, additional, Witbracht, Megan, additional, Kelley, Brendan, additional, Nguyen, Trung, additional, Womack, Kyle, additional, Mathews, Dana, additional, Quiceno, Mary, additional, Levey, Allan I., additional, Lah, James J., additional, Hajjar, Ihab, additional, Cellar, Janet S., additional, Burns, Jeffrey M., additional, Swerdlow, Russell H., additional, Brooks, William M., additional, Silverman, Daniel H.S., additional, Kremen, Sarah, additional, Apostolova, Liana, additional, Tingus, Kathleen, additional, Lu, Po H., additional, Bartzokis, George, additional, Woo, Ellen, additional, Teng, Edmond, additional, Graff-Radford, Neill R., additional, Parfitt, Francine, additional, Poki-Walker, Kim, additional, Farlow, Martin R., additional, Hake, Ann Marie, additional, Matthews, Brandy R., additional, Brosch, Jared R., additional, Herring, Scott, additional, van, Christopher H., additional, Mecca, Adam P., additional, Good, Susan P., additional, MacAvoy, Martha G., additional, Carson, Richard E., additional, Varma, Pradeep, additional, Chertkow, Howard, additional, Vaitekunis, Susan, additional, Hosein, Chris, additional, Black, Sandra, additional, Stefanovic, Bojana, additional, Heyn, Chris (Chinthaka), additional, Robin Hsiung, Ging-Yuek, additional, Kim, Ellen, additional, Mudge, Benita, additional, Sossi, Vesna, additional, Feldman, Howard, additional, Assaly, Michele, additional, Finger, Elizabeth, additional, Pasternak, Stephen, additional, Rachinsky, Irina, additional, Kertesz, Andrew, additional, Drost, Dick, additional, Rogers, John, additional, Grant, Ian, additional, Muse, Brittanie, additional, Rogalski, Emily, additional, Robson, Jordan, additional, Mesulam, M.-Marsel, additional, Kerwin, Diana, additional, Wu, Chuang-Kuo, additional, Johnson, Nancy, additional, Lipowski, Kristine, additional, Weintraub, Sandra, additional, Bonakdarpour, Borna, additional, Pomara, Nunzio, additional, Hernando, Raymundo, additional, Sarrael, Antero, additional, Rosen, Howard J., additional, Miller, Bruce L., additional, Perry, David, additional, Turner, Raymond Scott, additional, Johnson, Kathleen, additional, Reynolds, Brigid, additional, MCCann, Kelly, additional, Poe, Jessica, additional, Sperling, Reisa A., additional, Johnson, Keith A., additional, Marshall, Gad A., additional, Yesavage, Jerome, additional, Taylor, Joy L., additional, Chao, Steven, additional, Coleman, Jaila, additional, White, Jessica D., additional, Lane, Barton, additional, Rosen, Allyson, additional, Tinklenberg, Jared, additional, Belden, Christine M., additional, Atri, Alireza, additional, Clark, Kelly A., additional, Zamrini, Edward, additional, Sabbagh, Marwan, additional, Killiany, Ronald, additional, Stern, Robert, additional, Mez, Jesse, additional, Kowall, Neil, additional, Budson, Andrew E., additional, Obisesan, Thomas O., additional, Ntekim, Oyonumo E., additional, Wolday, Saba, additional, Khan, Javed I., additional, Nwulia, Evaristus, additional, Nadarajah, Sheeba, additional, Lerner, Alan, additional, Ogrocki, Paula, additional, Tatsuoka, Curtis, additional, Fatica, Parianne, additional, Maillard, Pauline, additional, Olichney, John, additional, Carmichael, Owen, additional, Bates, Vernice, additional, Capote, Horacio, additional, Rainka, Michelle, additional, Borrie, Michael, additional, Lee, T.-Y., additional, Bartha, Dr Rob, additional, Johnson, Sterling, additional, Asthana, Sanjay, additional, Carlsson, Cynthia M., additional, Perrin, Allison, additional, Burke, Anna, additional, Scharre, Douglas W., additional, Kataki, Maria, additional, Tarawneh, Rawan, additional, Hart, David, additional, Zimmerman, Earl A., additional, Celmins, Dzintra, additional, Miller, Delwyn D., additional, BolesPonto, Laura L., additional, Smith, Karen Ekstam, additional, Koleva, Hristina, additional, Shim, Hyungsub, additional, Nam, Ki Won, additional, Schultz, Susan K., additional, Williamson, Jeff D., additional, Craft, Suzanne, additional, Cleveland, Jo, additional, Yang, Mia, additional, Sink, Kaycee M., additional, Ott, Brian R., additional, Drake, Jonathan, additional, Tremont, Geoffrey, additional, Daiello, Lori A., additional, Drake, Jonathan D., additional, Ritter, Aaron, additional, Bernick, Charles, additional, Munic, Donna, additional, O'Connelll, Abigail, additional, Mintzer, Jacobo, additional, Wiliams, Arthur, additional, Masdeu, Joseph, additional, Shi, Jiong, additional, Garcia, Angelica, additional, Newhouse, Paul, additional, Potkin, Steven, additional, Salloway, Stephen, additional, Malloy, Paul, additional, Correia, Stephen, additional, Kittur, Smita, additional, Pearlson, Godfrey D., additional, Blank, Karen, additional, Anderson, Karen, additional, Flashman, Laura A., additional, Seltzer, Marc, additional, Hynes, Mary L., additional, Santulli, Robert B., additional, Relkin, Norman, additional, Chiang, Gloria, additional, Lee, Athena, additional, Lin, Michael, additional, Ravdin, Lisa, additional, Petersen, Ron, additional, Neylan, Thomas, additional, Grafman, Jordan, additional, Danowski, Sarah, additional, Nguyen-Barrera, Catherine, additional, Hayes, Jacqueline, additional, Finley, Shannon, additional, Bernstein, Matthew, additional, Senjem, Matt, additional, Foster, Norm, additional, Kim, Sungeun, additional, Sood, Ajay, additional, Blanchard, Kimberly S., additional, Fleischman, Debra, additional, Arfanakis, Konstantinos, additional, Varon, Daniel, additional, Greig, Maria T., additional, Petrella, Jeffrey R., additional, Goldstein, Bonnie, additional, Martin, Kimberly S., additional, Reist, Christopher, additional, Sadowsky, Carl, additional, Martinez, Walter, additional, Villena, Teresa, additional, Rosen, Howard, additional, Marshall, Gad, additional, Peskind, Elaine R., additional, Petrie, Eric C., additional, Li, Gail, additional, Mackin, Scott, additional, Jimenez-Maggiora, Gustavo, additional, Drake, Erin, additional, Donohue, Mike, additional, Nelson, Craig, additional, Bickford, David, additional, Butters, Meryl, additional, Zmuda, Michelle, additional, Reyes, Denise, additional, Faber, Kelley M., additional, Nudelman, Kelly N., additional, Au, Yiu Ho, additional, Scherer, Kelly, additional, Catalinotto, Daniel, additional, Stark, Samuel, additional, Ong, Elise, additional, and Fernandez, Dariella, additional
- Published
- 2023
- Full Text
- View/download PDF
7. Against the odds: Network and institutional pathways enabling agricultural diversification
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Jennifer Blesh, Zia Mehrabi, Hannah Wittman, Rachel Bezner Kerr, Dana James, Sidney Madsen, Olivia M. Smith, Sieglinde Snapp, Anne Elise Stratton, Mohamed Bakarr, Abram J. Bicksler, Ryan Galt, Lucas A. Garibaldi, Barbara Gemmill-Herren, Ingo Grass, Marney E. Isaac, Innocensia John, Sarah K. Jones, Christina M. Kennedy, Susanna Klassen, Christian Levers, Laura Vang Rasmussen, and Claire Kremen
- Subjects
social-ecological systems ,Earth and Planetary Sciences (miscellaneous) ,conceptual framework ,food security ,diversified farming system ,SDG 2 - Zero Hunger ,transitions ,biodiversity ,policy ,General Environmental Science - Abstract
Farming systems that support locally diverse agricultural production and high levels of biodiversity are in rapid decline, despite evidence of their benefits for climate, environmental health, and food security. Yet, agricultural policies, financial incentives, and market concentration increasingly constrain the viability of diversified farming systems. Here, we present a conceptual framework to identify novel processes that promote the emergence and sustainability of diversified farming systems, using three real-world examples where farming communities have found pathways to diversification despite major structural constraints. By applying our framework to analyze these bright spots in the United States, Brazil, and Malawi, we identify two distinct pathways—network and institutional—to diversification. These pathways emerge through alignment of factors related to social and ecological structure (policies, institutions, and environmental conditions) and agency (values, collective action, and management decisions). We find that, when network and institutional pathways operate in tandem, the potential to scale up diversification across farms and landscapes increases substantially.
- Published
- 2023
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8. Exploring scenarios for the food system–zoonotic risk interface
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Alon Shepon, Tong Wu, Claire Kremen, Tamar Dayan, Ivette Perfecto, Jessica Fanzo, Gidon Eshel, and Christopher D Golden
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Health (social science) ,Health Policy ,Public Health, Environmental and Occupational Health ,Medicine (miscellaneous) - Published
- 2023
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9. P-449 Role of education and empowerment in multiple myeloma patients
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Ahlstrom, Jennifer, primary, Flores, Marilú Nájera, additional, Campbell, Scott, additional, Roy, Tara, additional, Pérez, Patricia Alejandra Flores, additional, Martínez, Jorge Arturo Hurtado, additional, Sweeney, Nathan, additional, Kremen, Rachel, additional, and Hydren, Jay, additional
- Published
- 2023
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10. Combined Assessments of Patellar Tendon and Hamstring Tendon Parameters on Preoperative Magnetic Resonance Imaging Can Improve Predictability of Hamstring Tendon Autograft Diameter in the Setting of Anterior Cruciate Ligament Reconstruction
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Thomas J. Kremen, Michael T. Arnold, Myra Trivellas, Brendan Y. Shi, Kristofer J. Jones, and Ignacio Garcia-Mansilla
- Subjects
Rehabilitation ,Public Health, Environmental and Occupational Health ,Physical Therapy, Sports Therapy and Rehabilitation ,Orthopedics and Sports Medicine - Abstract
To evaluate whether preoperative magnetic resonance imaging (MRI) measurements of multiple tendon autograft sources could be used to improve estimates of intraoperative hamstring tendon autograft (HTA) diameter.Patients who underwent anterior cruciate ligament reconstruction with HTA at our institution were identified through electronic health records. Preoperative MRI tendon measurements of the patellar tendon (PT) length, PT width, PT thickness, quadriceps tendon thickness, semitendinosus tendon (ST) cross-sectional area (CSA), and gracilis tendon (GT) CSA were conducted by 2 independent evaluators using digital imaging measurement tools.A total of 53 patients met the inclusion criteria, with a mean HTA diameter of 7.98 ± 0.7 mm. Height greater than 1.63 m, weight greater than 63.4 kg, PT length greater than 4.2 cm, PT thickness greater than 0.33 cm, ST CSA greater than 10.8 mmBy combining PT length and PT thickness measurements with GT CSA measurements in a logit function model, we were able to show improved overall specificity, sensitivity, and accuracy of estimated HTA diameters in our data set when compared with assessments of anthropometric, ST CSA, GT CSA, or combined ST-GT CSA measurements in isolation.Preoperative MRI measurements may be used to screen whether a patient is likely to have an 8-mm graft in the setting of anterior cruciate ligament reconstruction with HTA and thus may help guide graft choice.
- Published
- 2022
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11. Exploring Factors Associated with Decisions about Feminizing Genitoplasty in Differences of Sex Development
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Jessica, Kremen, Rebecca M, Harris, Christopher E, Aston, Meghan, Perez, Paul F, Austin, Laurence, Baskin, Earl Y, Cheng, Allyson, Fried, Thomas, Kolon, Bradley, Kropp, Yegappan, Lakshmanan, Natalie J, Nokoff, Blake, Palmer, Alethea, Paradis, Dix, Poppas, Kristy J Scott, Reyes, Cortney, Wolfe-Christensen, David A, Diamond, Amy C, Tishelman, Larry L, Mullins, Amy B, Wisniewski, and Yee-Ming, Chan
- Subjects
Parents ,Adrenal Hyperplasia, Congenital ,Sexual Development ,Infant ,Obstetrics and Gynecology ,General Medicine ,Plastic Surgery Procedures ,Virilism ,Gynecologic Surgical Procedures ,Pediatrics, Perinatology and Child Health ,Humans ,Female ,Longitudinal Studies ,Child - Abstract
Infants with genital development considered atypical for assigned female sex may undergo feminizing genitoplasty (clitoroplasty and/or vaginoplasty) in early life. We sought to identify factors associated with parent/caregiver decisions regarding genitoplasty for their children with genital virilization.Longitudinal, observational study SETTING: Twelve pediatric centers in the United States with multidisciplinary differences/disorders of sex development clinics, 2015-2020 PARTICIPANTS: Children under 2 years old with genital appearance atypical for female sex of rearing and their parents/caregivers INTERVENTIONS/OUTCOME MEASURES: Data on the child's diagnosis and anatomic characteristics before surgery were extracted from the medical record. Parents/caregivers completed questionnaires on psychosocial distress, experience of uncertainty, cosmetic appearance of their child's genitalia, and demographic characteristics. Urologists rated cosmetic appearance. For 58 patients from the study cohort with genital virilization being raised as girls or gender-neutral, we compared these data across 3 groups based on the child's subsequent surgical intervention: (i) no surgery (n = 5), (ii) vaginoplasty without clitoroplasty (V-only) (n = 15), and (iii) vaginoplasty and clitoroplasty (V+C) (n = 38).Fathers' and urologists' ratings of genital appearance were more favorable in the no-surgery group than in the V-only and V+C groups. Clitorophallic length was greater in the V+C group compared with the V-only group, with substantial overlap between groups. Mothers' depressive and anxious symptoms were lower in the no-surgery group compared with the V-only and V+C groups.Surgical decisions were associated with fathers' and urologists' ratings of genital appearance, the child's anatomic characteristics, and mothers' depressive and anxious symptoms. Further research on surgical decision-making is needed to inform counseling practices.
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- 2022
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12. Remember this: Age moderation of genetic and environmental contributions to verbal episodic memory from midlife through late adulthood
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Luczak, Susan E., primary, Beam, Christopher R., additional, Pahlen, Shandell, additional, Lynch, Morgan, additional, Pilgrim, Matthew, additional, Reynolds, Chandra A., additional, Panizzon, Matthew S., additional, Catts, Vibeke S., additional, Christensen, Kaare, additional, Finkel, Deborah, additional, Franz, Carol E., additional, Kremen, William S., additional, Lee, Teresa, additional, McGue, Matt, additional, Nygaard, Marianne, additional, Plassman, Brenda L., additional, Whitfield, Keith E., additional, Pedersen, Nancy L., additional, and Gatz, Margaret, additional
- Published
- 2023
- Full Text
- View/download PDF
13. Corrigendum to “Hyperabundant black-tailed deer impact endangered Garry oak ecosystem floral and bumblebee communities” [Volume 38 (2022) e02237]
- Author
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Beckett, Kephra, primary, Elle, Elizabeth, additional, Kremen, Claire, additional, Sherwood, Abbie, additional, McComb, Sofie, additional, and Martin, Tara G., additional
- Published
- 2023
- Full Text
- View/download PDF
14. Semi-natural habitats on organic strawberry farms and in surrounding landscapes promote bird biodiversity and pest control potential
- Author
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Garcia, Karina, primary, Olimpi, Elissa M., additional, M’Gonigle, Leithen, additional, Karp, Daniel S., additional, Wilson-Rankin, Erin E., additional, Kremen, Claire, additional, and Gonthier, David J., additional
- Published
- 2023
- Full Text
- View/download PDF
15. Childhood Trauma Exposure and PTSD Diagnosis Interact With Polygenic Determinants of Hippocampal and Amygdala Volume
- Author
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Logue, Mark, primary, Zheng, Yuanchao, additional, Garrett, Melanie, additional, Maihofer, Adam, additional, Clarke, Emily, additional, Haswell, Courtney, additional, Sun, Delin, additional, Peverill, Matthew, additional, McLaughlin, Katie, additional, Sambrook, Kelly, additional, Davenport, Nicholas, additional, Disner, Seth, additional, Korgaonkar, Mayuresh, additional, Bryant, Richard, additional, Varkevisser, Tim, additional, Geuze, Elbert, additional, Beckham, Jean, additional, Kimbrel, Nathan, additional, Coleman, Jonathan, additional, Sullivan, Danielle, additional, Wolf, Erika, additional, Hayes, Jasmeet, additional, Verfaellie, Mieke, additional, Salat, David, additional, Spielberg, Jeffrey M., additional, McGlinchey, Regina, additional, Milberg, William, additional, Medland, Sarah E., additional, Nievergelt, Caroline, additional, Jahanshad, Neda, additional, Thompson, Paul M., additional, Kremen, William S., additional, and Morey, Rajendra, additional
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- 2023
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- View/download PDF
16. Against the odds: Network and institutional pathways enabling agricultural diversification
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Blesh, Jennifer, primary, Mehrabi, Zia, additional, Wittman, Hannah, additional, Kerr, Rachel Bezner, additional, James, Dana, additional, Madsen, Sidney, additional, Smith, Olivia M., additional, Snapp, Sieglinde, additional, Stratton, Anne Elise, additional, Bakarr, Mohamed, additional, Bicksler, Abram J., additional, Galt, Ryan, additional, Garibaldi, Lucas A., additional, Gemmill-Herren, Barbara, additional, Grass, Ingo, additional, Isaac, Marney E., additional, John, Innocensia, additional, Jones, Sarah K., additional, Kennedy, Christina M., additional, Klassen, Susanna, additional, Levers, Christian, additional, Rasmussen, Laura Vang, additional, and Kremen, Claire, additional
- Published
- 2023
- Full Text
- View/download PDF
17. Higher cortical thickness/volume in Alzheimer’s-related regions: Protective factor or risk factor?
- Author
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Williams, McKenna E., primary, Elman, Jeremy A., additional, Bell, Tyler R., additional, Dale, Anders M., additional, Eyler, Lisa T., additional, Fennema-Notestine, Christine, additional, Franz, Carol E., additional, Gillespie, Nathan A., additional, Hagler, Donald J., additional, Lyons, Michael J., additional, Mcevoy, Linda K., additional, Neale, Michael C., additional, Panizzon, Matthew S., additional, Reynolds, Chandra A., additional, Sanderson-Cimino, Mark, additional, and Kremen, William S., additional
- Published
- 2023
- Full Text
- View/download PDF
18. Higher cortical thickness/volume in Alzheimer’s-related regions: Protective factor or risk factor?
- Author
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McKenna E. Williams, Jeremy A. Elman, Tyler R. Bell, Anders M. Dale, Lisa T. Eyler, Christine Fennema-Notestine, Carol E. Franz, Nathan A. Gillespie, Donald J. Hagler, Michael J. Lyons, Linda K. Mcevoy, Michael C. Neale, Matthew S. Panizzon, Chandra A. Reynolds, Mark Sanderson-Cimino, and William S. Kremen
- Subjects
Aging ,General Neuroscience ,Neurology (clinical) ,Geriatrics and Gerontology ,Developmental Biology - Published
- 2023
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- View/download PDF
19. A Body-Neutral and Gender-Neutral Modified Ferriman–Gallwey Diagram
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Quentin Moyer, Frances Grimstad, Coleen R. Williams, and Jessica Kremen
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Gender dysphoria ,business.industry ,Diagram ,Hyperandrogenism ,Obstetrics and Gynecology ,Irregular menses ,General Medicine ,medicine.disease ,Dysphoria ,Pediatrics, Perinatology and Child Health ,Transgender ,Medicine ,Anxiety ,medicine.symptom ,business ,hirsutism ,Clinical psychology - Abstract
Background The modified Ferriman-Gallwey (mFG) diagram for scoring hirsutism uses images with traditionally Eurocentric feminine features. No reports have documented its utility in patients with other gender identities. Case A 16-year-old non-binary masculine patient, sex assigned female at birth, was seen for hyperandrogenism and irregular menses. They declined an exam citing body dysphoria, and declined self-documenting on the mFG diagram, expressing anxiety with gendered images. We subsequently developed a novel, gender-inclusive mFG diagram, which the patient was then comfortable using to document their hair pattern. Summary and Conclusion This case documents how the binary gendered characteristics of the mFG diagram can impact the care of patients. As gender expression is highly individual, we created the first gender-inclusive version of the mFG diagram to enhance care for all patients.
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- 2022
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20. Exploring scenarios for the food system–zoonotic risk interface
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Shepon, Alon, primary, Wu, Tong, additional, Kremen, Claire, additional, Dayan, Tamar, additional, Perfecto, Ivette, additional, Fanzo, Jessica, additional, Eshel, Gidon, additional, and Golden, Christopher D, additional
- Published
- 2023
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21. The Relationship of Attention-Deficit/Hyperactivity Disorder With Posttraumatic Stress Disorder: A Two-Sample Mendelian Randomization and Population-Based Sibling Comparison Study
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Wendt, Frank R., primary, Garcia-Argibay, Miguel, additional, Cabrera-Mendoza, Brenda, additional, Valdimarsdóttir, Unnur A., additional, Gelernter, Joel, additional, Stein, Murray B., additional, Nivard, Michel G., additional, Maihofer, Adam X., additional, Nievergelt, Caroline M., additional, Larsson, Henrik, additional, Mattheisen, Manuel, additional, Polimanti, Renato, additional, Meier, Sandra M., additional, Choi, Karmel W., additional, Coleman, Jonathan R.I., additional, Daskalakis, Nikolaos P., additional, Denckla, Christy A., additional, Ketema, Elizabeth, additional, Morey, Rajendra A., additional, Ratanatharathorn, Andrew, additional, Torres, Katy, additional, Wingo, Aliza P., additional, Zai, Clement C., additional, Aiello, Allison E., additional, Almli, Lynn M., additional, Amstadter, Ananda B., additional, Andersen, Soren B., additional, Andreassen, Ole A., additional, Arbisi, Paul A., additional, Ashley-Koch, Allison E., additional, Austin, S. Bryn, additional, Avdibegovic, Esmina, additional, Borglum, Anders D., additional, Babic, Dragan, additional, Bækvad-Hansen, Marie, additional, Baker, Dewleen G., additional, Beckham, Jean C., additional, Bierut, Laura J., additional, Bisson, Jonathan I., additional, Boks, Marco P., additional, Bolger, Elizabeth A., additional, Bradley, Bekh, additional, Brashear, Meghan, additional, Breen, Gerome, additional, Bryant, Richard A., additional, Bustamante, Angela C., additional, Bybjerg-Grauholm, Jonas, additional, Calabrese, Joseph R., additional, Caldas-de-Almeida, Jose Miguel, additional, Chen, Chia-Yen, additional, Dale, Anders M., additional, Dalvie, Shareefa, additional, Deckert, Jürgen, additional, Delahanty, Douglas L., additional, Dennis, Michelle F., additional, Disner, Seth G., additional, Domschke, Katharina, additional, Duncan, Laramie E., additional, Kulenovic, Alma Dzubur, additional, Erbes, Christopher R., additional, Evans, Alexandra, additional, Farrer, Lindsay A., additional, Feeny, Norah C., additional, Flory, Janine D., additional, Forbes, David, additional, Franz, Carol E., additional, Galea, Sandro, additional, Garrett, Melanie E., additional, Gautam, Aarti, additional, Gelaye, Bizu, additional, Geuze, Elbert, additional, Gillespie, Charles F., additional, Uka, Aferdita Goci, additional, Gordon, Scott D., additional, Guffanti, Guia, additional, Hammamieh, Rasha, additional, Hauser, Michael A., additional, Heath, Andrew C., additional, Hemmings, Sian M.J., additional, Hougaard, David Michael, additional, Jakovljevic, Miro, additional, Jett, Marti, additional, Johnson, Eric Otto, additional, Jones, Ian, additional, Jovanovic, Tanja, additional, Qin, Xue-Jun, additional, Karstoft, Karen-Inge, additional, Kaufman, Milissa L., additional, Kessler, Ronald C., additional, Khan, Alaptagin, additional, Kimbrel, Nathan A., additional, King, Anthony P., additional, Koen, Nastassja, additional, Kranzler, Henry R., additional, Kremen, William S., additional, Lawford, Bruce R., additional, Lebois, Lauren A.M., additional, Lewis, Catrin, additional, Liberzon, Israel, additional, Linnstaedt, Sarah D., additional, Logue, Mark W., additional, Lori, Adriana, additional, Lugonja, Bozo, additional, Luykx, Jurjen J., additional, Lyons, Michael J., additional, Maples-Keller, Jessica L., additional, Marmar, Charles, additional, Martin, Nicholas G., additional, Maurer, Douglas, additional, Mavissakalian, Matig R., additional, McFarlane, Alexander, additional, McGlinchey, Regina E., additional, McLaughlin, Katie A., additional, McLean, Samuel A., additional, Mehta, Divya, additional, Mellor, Rebecca, additional, Michopoulos, Vasiliki, additional, Milberg, William, additional, Miller, Mark W., additional, Morris, Charles Phillip, additional, Mors, Ole, additional, Mortensen, Preben Bo, additional, Nelson, Elliot C., additional, Nordentoft, Merete, additional, Norman, Sonya B., additional, O’Donnell, Meaghan, additional, Orcutt, Holly K., additional, Panizzon, Matthew S., additional, Peters, Edward S., additional, Peterson, Alan L., additional, Peverill, Matthew, additional, Pietrzak, Robert H., additional, Polusny, Melissa A., additional, Rice, John P., additional, Risbrough, Victoria B., additional, Roberts, Andrea L., additional, Rothbaum, Alex O., additional, Rothbaum, Barbara O., additional, Roy-Byrne, Peter, additional, Ruggiero, Kenneth J., additional, Rung, Ariane, additional, Rutten, Bart P.F., additional, Saccone, Nancy L., additional, Sanchez, Sixto E., additional, Schijven, Dick, additional, Seedat, Soraya, additional, Seligowski, Antonia V., additional, Seng, Julia S., additional, Sheerin, Christina M., additional, Silove, Derrick, additional, Smith, Alicia K., additional, Smoller, Jordan W., additional, Sponheim, Scott R., additional, Stein, Dan J., additional, Stevens, Jennifer S., additional, Teicher, Martin H., additional, Thompson, Wesley K., additional, Trapido, Edward, additional, Uddin, Monica, additional, Ursano, Robert J., additional, Luella van den Heuvel, Leigh, additional, Van Hooff, Miranda, additional, Vermetten, Eric, additional, Vinkers, Christiaan, additional, Voisey, Joanne, additional, Wang, Yunpeng, additional, Wang, Zhewu, additional, Werge, Thomas, additional, Williams, Michelle A., additional, Williamson, Douglas E., additional, Winternitz, Sherry, additional, Wolf, Christiane, additional, Wolf, Erika J., additional, Yehuda, Rachel, additional, Young, Keith A., additional, Young, Ross McD., additional, Zhao, Hongyu, additional, Zoellner, Lori A., additional, Haas, Magali, additional, Lasseter, Heather, additional, Provost, Allison C., additional, Salem, Rany M., additional, Sebat, Jonathan, additional, Shaffer, Richard, additional, Wu, Tianying, additional, Ripke, Stephan, additional, Daly, Mark J., additional, Ressler, Kerry J., additional, and Koenen, Karestan C., additional
- Published
- 2023
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22. TEMPORARY REMOVAL: Fertility Preservation in Transfeminine Adolescents – Case Series of Combined Testicular Sperm Extraction and Histrelin Acetate Subcutaneous Implant Placement
- Author
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Bortnick, Eric M., primary, Barrera, Ellis, additional, Locks, Rachel, additional, Kremen, Jessica, additional, and Yu, Richard, additional
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- 2023
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- View/download PDF
23. TEMPORARY REMOVAL: Fertility Preservation in Transfeminine Adolescents – Case Series of Combined Testicular Sperm Extraction and Histrelin Acetate Subcutaneous Implant Placement
- Author
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Eric M. Bortnick, Ellis Barrera, Rachel Locks, Jessica Kremen, and Richard Yu
- Subjects
Urology ,Pediatrics, Perinatology and Child Health - Published
- 2023
- Full Text
- View/download PDF
24. Childhood Trauma Exposure and PTSD Diagnosis Interact With Polygenic Determinants of Hippocampal and Amygdala Volume
- Author
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Mark Logue, Yuanchao Zheng, Melanie Garrett, Adam Maihofer, Emily Clarke, Courtney Haswell, Delin Sun, Matthew Peverill, Katie McLaughlin, Kelly Sambrook, Nicholas Davenport, Seth Disner, Mayuresh Korgaonkar, Richard Bryant, Tim Varkevisser, Elbert Geuze, Jean Beckham, Nathan Kimbrel, Jonathan Coleman, Danielle Sullivan, Erika Wolf, Jasmeet Hayes, Mieke Verfaellie, David Salat, Jeffrey M. Spielberg, Regina McGlinchey, William Milberg, Sarah E. Medland, Caroline Nievergelt, Neda Jahanshad, Paul M. Thompson, William S. Kremen, and Rajendra Morey
- Subjects
Biological Psychiatry - Published
- 2023
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25. Paradoxical cognitive trajectories in men from earlier to later adulthood
- Author
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Graham M L Eglit, Jeremy A. Elman, Linda K. McEvoy, Michael C. Neale, Daniel E. Gustavson, Mark Sanderson-Cimino, McKenna E. Williams, Sean N. Hatton, Mark W. Logue, Chandra A. Reynolds, William S. Kremen, Richard L. Hauger, Carol E. Franz, Lisa T. Eyler, Christine Fennema-Notestine, Amy J. Jak, Hong Xian, Anders M. Dale, Xin M. Tu, Nathan A. Gillespie, Nathan Whitsel, M. Panizzon, Olivia K. Puckett, Michael J. Lyons, Donald J. Hagler, Ruth E. McKenzie, and Rosemary Toomey
- Subjects
Male ,Cognitive aging ,Aging ,Twins ,Neuropsychological Tests ,Executive Function ,Cognition ,immune system diseases ,Medicine ,Longitudinal Studies ,Young adult ,skin and connective tissue diseases ,General Neuroscience ,Neuropsychology ,Brain ,Middle Aged ,Memory, Short-Term ,cardiovascular system ,Twin Studies as Topic ,Life course approach ,Mental health ,Adult ,Clinical Sciences ,General cognitive ability ,Article ,Young Adult ,Apolipoproteins E ,Memory ,Behavioral and Social Science ,Acquired Cognitive Impairment ,Humans ,Dementia ,cardiovascular diseases ,Aged ,Neurology & Neurosurgery ,business.industry ,Working memory ,Neurosciences ,medicine.disease ,Twin study ,Brain Disorders ,Short-Term ,Neurology (clinical) ,Geriatrics and Gerontology ,business ,Developmental Biology ,Demography - Abstract
Because longitudinal studies of aging typically lack cognitive data from earlier ages, it is unclear how general cognitive ability (GCA) changes throughout the life course. In 1173 Vietnam Era Twin Study of Aging (VETSA) participants, we assessed young adult GCA at average age 20 and current GCA at 3 VETSA assessments beginning at average age 56. The same GCA index was used throughout. Higher young adult GCA and better GCA maintenance were associated with stronger specific cognitive abilities from age 51 to 73. Given equivalent GCA at age 56, individuals who had higher age 20 GCA outperformed those whose GCA remained stable in terms of memory, executive function, and working memory abilities from age 51 to 73. Thus, paradoxically, despite poorer maintenance of GCA, high young adult GCA still conferred benefits. Advanced predicted brain age and the combination of elevated vascular burden and APOE-ε4 status were associated with poorer maintenance of GCA. These findings highlight the importance of distinguishing between peak and current GCA for greater understanding of cognitive aging.
- Published
- 2022
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26. Lifestyle and the aging brain: interactive effects of modifiable lifestyle behaviors and cognitive ability in men from midlife to old age
- Author
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Mark Sanderson-Cimino, Ruth McKenzie, Matthew S. Panizzon, Carol E. Franz, Christine Fennema-Notestine, Jeremy A. Elman, McKenna E. Williams, William S. Kremen, Hong Xian, Anders M. Dale, Chandra A. Reynolds, Sean N. Hatton, Xin M. Tu, Michael C. Neale, Rahul C. Pearce, Nathan Whitsel, Michael J. Lyons, Donald J. Hagler, Richard L. Hauger, Lisa T. Eyler, Rosemary Toomey, Teresa Warren, Nathan A. Gillespie, and Olivia K. Puckett
- Subjects
Male ,Gerontology ,Aging ,Disease ,Neurodegenerative ,Alzheimer's disease brain signature ,Alzheimer's Disease ,Cognition ,Cognitive Reserve ,Medicine ,Aging brain ,Young adult ,skin and connective tissue diseases ,Cognitive reserve ,General Neuroscience ,Age Factors ,Modifiable lifestyle behavior ,Middle Aged ,White Matter ,Neurological ,Biomedical Imaging ,Independent Living ,Adult ,White matter abnormalities ,Clinical Sciences ,General cognitive ability ,Affect (psychology) ,Article ,Young Adult ,Alzheimer Disease ,Clinical Research ,Behavioral and Social Science ,Acquired Cognitive Impairment ,Humans ,Dementia ,Healthy Lifestyle ,Life Style ,Aged ,Behavior ,Neurology & Neurosurgery ,business.industry ,Prevention ,Neurosciences ,Mild cognitive impairment ,Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) ,medicine.disease ,Twin study ,Brain Disorders ,Brain aging ,Neurology (clinical) ,Geriatrics and Gerontology ,business ,Developmental Biology - Abstract
We examined the influence of lifestyle on brain aging after nearly 30 years, and tested the hypothesis that young adult general cognitive ability (GCA) would moderate these effects. In the community-dwelling Vietnam Era Twin Study of Aging (VETSA), 431 largely non-Hispanic white men completed a test of GCA at mean age 20. We created a modifiable lifestyle behavior composite from data collected at mean age 40. During VETSA, MRI-based measures at mean age 68 included predicted brain age difference (PBAD), Alzheimer's disease (AD) brain signature, and abnormal white matter scores. There were significant main effects of young adult GCA and lifestyle on PBAD and the AD signature (ps ≤ 0.012), and a GCA-by-lifestyle interaction on both (ps ≤ 0.006). Regardless of GCA level, having more favorable lifestyle behaviors predicted less advanced brain age and less AD-like brain aging. Unfavorable lifestyles predicted advanced brain aging in those with lower age 20 GCA, but did not affect brain aging in those with higher age 20 GCA. Targeting early lifestyle modification may promote dementia risk reduction, especially among lower reserve individuals.
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- 2021
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27. Ambient Air Pollution Exposure is Associated with Lower Mri-Assessed Locus Coeruleus Integrity
- Author
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Puckett, Olivia K., primary, Fennema-Notestine, Christine, additional, Hagler, Donald J., additional, Braskie, Meredith N., additional, Chen, JC, additional, Finch, Caleb E, additional, Kaufman, Joel D., additional, Petkus, Andrew J., additional, Salminen, Lauren E., additional, Thompson, Paul M., additional, Wang, Xinhui, additional, Kremen, William S., additional, Franz, Carol E., additional, and Elman, Jeremy A., additional
- Published
- 2023
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28. Change in Hippocampal Volume is Highly Heritable and Associated with Genetic Risk for Alzheimer's Disease
- Author
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Panizzon, Matthew S., primary, Elman, Jeremy A., additional, Reynolds, Chandra A., additional, Andreassen, Ole A., additional, Dale, Anders M., additional, Eglit, Graham M.L., additional, Eyler, Lisa T., additional, Fennema-Notestine, Christine, additional, Franz, Carol E., additional, Gillespie, Nathan A., additional, Hagler, Donald J., additional, Hatton, Sean N., additional, Hauger, Richard L., additional, Jak, Amy J., additional, Logue, Mark, additional, Lyons, Michael J., additional, McEvoy, Linda, additional, McKenzie, Ruth, additional, Puckett, Olivia K., additional, Neale, Michael C., additional, Sanderson-Cimino, Mark, additional, Toomey, Rosemary, additional, Tu, Xin, additional, Whitsel, Nathan, additional, Williams, McKenna E., additional, Xian, Hong, additional, and Kremen, William S., additional
- Published
- 2023
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29. Associations among executive function Abilities, free Water, and white matter microstructure in early old age
- Author
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Gustavson, Daniel E., primary, Archer, Derek B., additional, Elman, Jeremy A., additional, Puckett, Olivia K., additional, Fennema-Notestine, Christine, additional, Panizzon, Matthew S., additional, Shashikumar, Niranjana, additional, Hohman, Timothy J., additional, Jefferson, Angela L., additional, Eyler, Lisa T., additional, McEvoy, Linda K., additional, Lyons, Michael J., additional, Franz, Carol E., additional, and Kremen, William S., additional
- Published
- 2023
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30. Exploring Factors Associated with Decisions about Feminizing Genitoplasty in Differences of Sex Development
- Author
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Kremen, Jessica, primary, Harris, Rebecca M., additional, Aston, Christopher E., additional, Perez, Meghan, additional, Austin, Paul F., additional, Baskin, Laurence, additional, Cheng, Earl Y., additional, Fried, Allyson, additional, Kolon, Thomas, additional, Kropp, Bradley, additional, Lakshmanan, Yegappan, additional, Nokoff, Natalie J., additional, Palmer, Blake, additional, Paradis, Alethea, additional, Poppas, Dix, additional, Reyes, Kristy J. Scott, additional, Wolfe-Christensen, Cortney, additional, Diamond, David A., additional, Tishelman, Amy C., additional, Mullins, Larry L., additional, Wisniewski, Amy B., additional, and Chan, Yee-Ming, additional
- Published
- 2022
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31. Common pesticides disrupt critical ecological interactions
- Author
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Sargent, Risa D., primary, Carrillo, Juli, additional, and Kremen, Claire, additional
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- 2022
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32. Combined Assessments of Patellar Tendon and Hamstring Tendon Parameters on Preoperative Magnetic Resonance Imaging Can Improve Predictability of Hamstring Tendon Autograft Diameter in the Setting of Anterior Cruciate Ligament Reconstruction
- Author
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Kremen, Thomas J., primary, Arnold, Michael T., additional, Trivellas, Myra, additional, Shi, Brendan Y., additional, Jones, Kristofer J., additional, and Garcia-Mansilla, Ignacio, additional
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- 2022
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33. Breakthrough Bleeding in Transgender and Gender Diverse Adolescents and Young Adults on Long-Term Testosterone
- Author
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Frances Grimstad, Brittany M. Charlton, Jessica Shim, Jessica Kremen, and Elizabeth R. Boskey
- Subjects
Gender dysphoria ,endocrine system ,Pediatrics ,medicine.medical_specialty ,Metrorrhagia ,Adolescent ,Transgender Persons ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Breakthrough bleeding ,medicine ,Humans ,Testosterone ,Vaginal bleeding ,030212 general & internal medicine ,Young adult ,Child ,Retrospective Studies ,030219 obstetrics & reproductive medicine ,business.industry ,Gender Identity ,virus diseases ,Obstetrics and Gynecology ,Testosterone (patch) ,Retrospective cohort study ,General Medicine ,medicine.disease ,Pediatrics, Perinatology and Child Health ,Female ,Amenorrhea ,medicine.symptom ,business ,Body mass index - Abstract
Amenorrhea is a goal of many transgender and gender diverse adolescent and young adult (TGD AYA) patients on testosterone gender-affirming hormone therapy (T-GAHT). Breakthrough bleeding can contribute to worsening gender dysphoria. Our objective was to evaluate breakthrough bleeding in TGD AYA on T-GAHT.Institutional review board-approved retrospective cohort.Tertiary-care children's hospital.TGD AYA on T-GAHT1 year.None; observational.Presence of, and risk factors for, breakthrough bleeding.Of the 232 patients who met inclusion criteria, one-fourth (n = 58) had 1 or more episodes of breakthrough bleeding, defined as bleeding after more than 1 year on T-GAHT. In comparing patients with breakthrough bleeding to those without, there were no significant differences between age of initiation, body mass index (BMI), race/ethnicity, testosterone type used, use of additional menstrual suppression, serum testosterone, or estradiol levels. Patients with breakthrough bleeding patients were on T-GAHT longer (37.3 ± 17.0 vs 28.5 ± 14.6 months, P.001) and were more likely to have endometriosis (P = .049). Breakthrough bleeding began at a mean of 24.3 ± 17.2 months after T-GAHT initiation. Of those with breakthrough bleeding, 46 (79.3%) had no known cause, 10 (17.2%) bled only with missed T-GAHT doses, and 2 (3.4%) bled only when withdrawing from concomitant menstrual suppression. No breakthrough bleeding management method was found to be superior.Breakthrough bleeding is relatively common (25%) on T-GAHT despite early amenorrhea. Most cases do not have an identifiable cause. Our data did not show superiority of any 1 method for managing breakthrough bleeding on T-GAHT.
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- 2021
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34. Hyperabundant black-tailed deer impact endangered Garry oak ecosystem floral and bumblebee communities
- Author
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Beckett, Kephra, primary, Elle, Elizabeth, additional, Kremen, Claire, additional, Sherwood, Abbie, additional, McComb, Sofie, additional, and Martin, Tara G., additional
- Published
- 2022
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35. Hotspot of human verbal memory encoding in the left anterior prefrontal cortex
- Author
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Topçu, Çağdaş, primary, Marks, Victoria S., additional, Saboo, Krishnakant V., additional, Lech, Michał, additional, Nejedly, Petr, additional, Kremen, Vaclav, additional, Worrell, Gregory A., additional, and Kucewicz, Michal T., additional
- Published
- 2022
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36. Remember this: Age moderation of genetic and environmental contributions to verbal episodic memory from midlife through late adulthood
- Author
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Susan E. Luczak, Christopher R. Beam, Shandell Pahlen, Morgan Lynch, Matthew Pilgrim, Chandra A. Reynolds, Matthew S. Panizzon, Vibeke S. Catts, Kaare Christensen, Deborah Finkel, Carol E. Franz, William S. Kremen, Teresa Lee, Matt McGue, Marianne Nygaard, Brenda L. Plassman, Keith E. Whitfield, Nancy L. Pedersen, and Margaret Gatz
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Arts and Humanities (miscellaneous) ,Developmental and Educational Psychology ,Experimental and Cognitive Psychology - Published
- 2023
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37. Corrigendum to 'Hyperabundant black-tailed deer impact endangered Garry oak ecosystem floral and bumblebee communities' [Volume 38 (2022) e02237]
- Author
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Kephra Beckett, Elizabeth Elle, Claire Kremen, Abbie Sherwood, Sofie McComb, and Tara G. Martin
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Ecology ,Ecology, Evolution, Behavior and Systematics ,Nature and Landscape Conservation - Published
- 2023
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38. Semi-natural habitats on organic strawberry farms and in surrounding landscapes promote bird biodiversity and pest control potential
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Karina Garcia, Elissa M. Olimpi, Leithen M’Gonigle, Daniel S. Karp, Erin E. Wilson-Rankin, Claire Kremen, and David J. Gonthier
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Ecology ,Animal Science and Zoology ,Agronomy and Crop Science - Published
- 2023
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39. Genetic and Environmental Influences on Structural and Diffusion-Based Alzheimer’s Disease Neuroimaging Signatures Across Midlife and Early Old Age
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McKenna E. Williams, Nathan A. Gillespie, Tyler R. Bell, Anders M. Dale, Jeremy A. Elman, Lisa T. Eyler, Christine Fennema-Notestine, Carol E. Franz, Donald J. Hagler, Michael J. Lyons, Linda K. McEvoy, Michael C. Neale, Matthew S. Panizzon, Chandra A. Reynolds, Mark Sanderson-Cimino, and William S. Kremen
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Cognitive Neuroscience ,Radiology, Nuclear Medicine and imaging ,Neurology (clinical) ,Biological Psychiatry - Abstract
Composite scores of MRI-derived metrics in brain regions associated with Alzheimer's disease (AD), commonly termed 'AD signatures,' have been developed to distinguish early AD-related atrophy from normal age-associated changes. Diffusion-based gray matter signatures may be more sensitive to early AD-related changes compared to thickness/volume-based signatures, demonstrating their potential clinical utility. The timing of early (i.e., midlife) changes in AD signatures from different modalities, and whether diffusion- and thickness/volume-based signatures each capture unique, AD-related phenotypic or genetic information, remains unknown.Our validated thickness/volume signature, our novel mean diffusivity (MD) signature, and an MRI-derived measure of brain age were used in biometrical analyses to examine genetic and environmental influences on the measures, as well as phenotypic and genetic relationships between measures over 12 years. Participants were 736 men from three waves of the Vietnam Era Twin Study of Aging (VETSA; baseline age=56.1, SD=2.6, range=51.1-60.2). Subsequent waves were at approximately 5.7-year intervals.MD and thickness/volume signatures were highly heritable (56-72%). Baseline MD signatures predicted thickness/volume signatures over a decade later, but baseline thickness/volume signatures showed a significantly weaker relationship with future MD signatures. AD signatures and brain age were correlated, but each measure captured unique phenotypic and genetic variance.Cortical MD and thickness/volume AD signatures are heritable, and each signature captures unique variance that is also not explained by brain age. Moreover, results are in line with changes in MD emerging before changes in cortical thickness, underscoring the utility of MD as a very early predictor of AD risk.
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- 2022
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40. Pesticide exposure of wild bees and honey bees foraging from field border flowers in intensively managed agriculture areas
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Ward, Laura T., primary, Hladik, Michelle L., additional, Guzman, Aidee, additional, Winsemius, Sara, additional, Bautista, Ariana, additional, Kremen, Claire, additional, and Mills, Nicholas J., additional
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- 2022
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41. Genetic and Environmental Influences on Structural and Diffusion-Based Alzheimer’s Disease Neuroimaging Signatures Across Midlife and Early Old Age
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Williams, McKenna E., primary, Gillespie, Nathan A., additional, Bell, Tyler R., additional, Dale, Anders M., additional, Elman, Jeremy A., additional, Eyler, Lisa T., additional, Fennema-Notestine, Christine, additional, Franz, Carol E., additional, Hagler, Donald J., additional, Lyons, Michael J., additional, McEvoy, Linda K., additional, Neale, Michael C., additional, Panizzon, Matthew S., additional, Reynolds, Chandra A., additional, Sanderson-Cimino, Mark, additional, and Kremen, William S., additional
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- 2022
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42. Can soccer players return to sport after knee realignment osteotomy?
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Chernoff, Daniel J., primary, Kremen, Thomas J., additional, and Jones, Kristofer J., additional
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- 2022
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43. Clustering of Genetic Effects on Cortical Morphology and Links to Psychiatric Disorders
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Makowski, Carolina, primary, van der Meer, Dennis, additional, Dong, Weixiu, additional, Wang, Hao, additional, Wu, Yan, additional, Zou, Jingjing, additional, Liu, Cin, additional, Rosenthal, Sara B., additional, Hagler, Donald J., additional, Fan, Chun Chieh, additional, Kremen, William S., additional, Andreassen, Ole A., additional, Jernigan, Terry L., additional, Dale, Anders M., additional, Zhang, Kun, additional, Visscher, Peter M., additional, Yang, Jian, additional, and Chen, Chi-Hua, additional
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- 2022
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44. Amyloid-β Positivity Predicts Cognitive Decline but Cognition Predicts Progression to Amyloid-β Positivity
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William S. Kremen, Jeremy A. Elman, Mark E Sanderson-Cimino, Daniel E. Gustavson, Michael J. Lyons, Alzheimer’s Disease Neuroimaging Initiative, Carol E. Franz, and Matthew S. Panizzon
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0301 basic medicine ,Oncology ,Apolipoprotein E ,Aging ,Disease ,Neuropsychological Tests ,Neurodegenerative ,Alzheimer's Disease ,Medical and Health Sciences ,Cognition ,0302 clinical medicine ,2.1 Biological and endogenous factors ,Medicine ,Aetiology ,Cognitive decline ,Psychiatry ,β-amyloid ,beta-amyloid ,Biological Sciences ,Biomarker trajectories ,Neurological ,Disease Progression ,Biomarker (medicine) ,Alzheimer’s disease ,medicine.medical_specialty ,tau Proteins ,03 medical and health sciences ,Neuroimaging ,Alzheimer Disease ,Internal medicine ,mental disorders ,Acquired Cognitive Impairment ,Humans ,Cognitive Dysfunction ,Effects of sleep deprivation on cognitive performance ,Pathological ,Biological Psychiatry ,Amyloid beta-Peptides ,business.industry ,Psychology and Cognitive Sciences ,Neurosciences ,Mild cognitive impairment ,Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) ,AD ,Alzheimer’s Disease Neuroimaging Initiative ,MCI ,Brain Disorders ,030104 developmental biology ,Dementia ,business ,Amyloid accumulation ,Biomarkers ,030217 neurology & neurosurgery - Abstract
Background Stage 1 of the National Institute on Aging–Alzheimer’s Association’s proposed Alzheimer’s disease continuum is defined as amyloid-β (Aβ) positive but cognitively normal. Identifying at-risk individuals before Aβ reaches pathological levels could have great benefits for early intervention. Although Aβ levels become abnormal long before severe cognitive impairments appear, increasing evidence suggests that subtle cognitive changes may begin early, potentially before Aβ surpasses the threshold for abnormality. We examined whether baseline cognitive performance would predict progression from normal to abnormal levels of Aβ. Methods We examined the association of baseline cognitive composites (Preclinical Alzheimer Cognitive Composite, Alzheimer’s Disease Neuroimaging Initiative (ADNI) memory factor composite) with progression to Aβ positivity in 292 nondemented, Aβ-negative ADNI participants. Additional analyses included continuous cerebrospinal fluid biomarker levels to examine the effects of subthreshold pathology. Results Forty participants progressed to Aβ positivity during follow-up. Poorer baseline performance on both cognitive measures was significantly associated with increased odds of progression. More abnormal levels of baseline cerebrospinal fluid phosphorylated tau and subthreshold Aβ were associated with increased odds of progression to Aβ positivity. Nevertheless, baseline ADNI memory factor composite performance predicted progression even after controlling for baseline biomarker levels and APOE genotype (Preclinical Alzheimer Cognitive Composite was trend level). Survival analyses were largely consistent: controlling for baseline biomarker levels, baseline Preclinical Alzheimer Cognitive Composite still significantly predicted progression time to Aβ positivity (ADNI memory factor composite was trend level). Conclusions The possibility of intervening before Aβ reaches pathological levels is of obvious benefit. Low-cost, noninvasive cognitive measures can be informative for determining who is likely to progress to Aβ positivity, even after accounting for baseline subthreshold biomarker levels.
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- 2020
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45. Time to Integrate Pollinator Science into Soybean Production
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Lisa A. Schulte, Lucas Alejandro Garibaldi, Dulce Sol Gómez Carella, Claire Kremen, and Diego N. Nabaes Jodar
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Crops, Agricultural ,0106 biological sciences ,Pollination ,Biodiversity ,Biology ,Agricultura (General) ,010603 evolutionary biology ,01 natural sciences ,Pollinator ,Biodiversidad y Conservación ,Wild Pollinators ,Productivity ,Hectare ,Ecosystem ,Ecology, Evolution, Behavior and Systematics ,Honey Bee ,Agroforestry ,business.industry ,Crop yield ,fungi ,food and beverages ,Agriculture ,Ecología ,Bees ,010602 entomology ,Habitat ,Biodiversity Conservation ,Crop Yield ,Soybeans ,Soybean ,business - Abstract
Fil: Garibaldi, Lucas A. Universidad Nacional de Río Negro. Instituto de Investigaciones en Recursos Naturales, Agroecología y Desarrollo Rural. Río Negro, Argentina. Fil: Garibaldi, Lucas A. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Recursos Naturales, Agroecología y Desarrollo Rural. Río Negro, Argentina. Fil: Schulte, Lisa A. Iowa State University. Bioeconomy Institute. Department of Natural Resource Ecology and Management. Estados Unidos. Fil: Nabaes Jodar, Diego N. Universidad Nacional de Río Negro. Instituto de Investigaciones en Recursos Naturales, Agroecología y Desarrollo Rural. Río Negro, Argentina. Fil: Nabaes Jodar, Diego N. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Recursos Naturales, Agroecología y Desarrollo Rural. Río Negro, Argentina. Fil: Gómez Carella, Dulce S. Universidad Nacional de Río Negro. Instituto de Investigaciones en Recursos Naturales, Agroecología y Desarrollo Rural. Río Negro, Argentina. Fil: Gómez Carella, Dulce S. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Recursos Naturales, Agroecología y Desarrollo Rural. Río Negro, Argentina. Fil: Kremen, Claire. University of British Columbia. Institute for Resources, Environment and Sustainability. Canada. Soybeans cover 129 million hectares globally. Soybean productivity can increase with pollinator management, but soybean cultivation practices commonly ignore biotic pollination. If pollinator habitats are created within soybean landscapes and policies to limit agricultural expansion are implemented, millions of hectares could be restored for biodiversity without loss of soybean production. .
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- 2021
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46. Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information
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Maihofer, Adam X., primary, Choi, Karmel W., additional, Coleman, Jonathan R.I., additional, Daskalakis, Nikolaos P., additional, Denckla, Christy A., additional, Ketema, Elizabeth, additional, Morey, Rajendra A., additional, Polimanti, Renato, additional, Ratanatharathorn, Andrew, additional, Torres, Katy, additional, Wingo, Aliza P., additional, Zai, Clement C., additional, Aiello, Allison E., additional, Almli, Lynn M., additional, Amstadter, Ananda B., additional, Andersen, Soren B., additional, Andreassen, Ole A., additional, Arbisi, Paul A., additional, Ashley-Koch, Allison E., additional, Austin, S. Bryn, additional, Avdibegović, Esmina, additional, Borglum, Anders D., additional, Babić, Dragan, additional, Bækvad-Hansen, Marie, additional, Baker, Dewleen G., additional, Beckham, Jean C., additional, Bierut, Laura J., additional, Bisson, Jonathan I., additional, Boks, Marco P., additional, Bolger, Elizabeth A., additional, Bradley, Bekh, additional, Brashear, Meghan, additional, Breen, Gerome, additional, Bryant, Richard A., additional, Bustamante, Angela C., additional, Bybjerg-Grauholm, Jonas, additional, Calabrese, Joseph R., additional, Caldas-de-Almeida, José M., additional, Chen, Chia-Yen, additional, Dale, Anders M., additional, Dalvie, Shareefa, additional, Deckert, Jürgen, additional, Delahanty, Douglas L., additional, Dennis, Michelle F., additional, Disner, Seth G., additional, Domschke, Katharina, additional, Duncan, Laramie E., additional, Džubur Kulenović, Alma, additional, Erbes, Christopher R., additional, Evans, Alexandra, additional, Farrer, Lindsay A., additional, Feeny, Norah C., additional, Flory, Janine D., additional, Forbes, David, additional, Franz, Carol E., additional, Galea, Sandro, additional, Garrett, Melanie E., additional, Gautam, Aarti, additional, Gelaye, Bizu, additional, Gelernter, Joel, additional, Geuze, Elbert, additional, Gillespie, Charles F., additional, Goçi, Aferdita, additional, Gordon, Scott D., additional, Guffanti, Guia, additional, Hammamieh, Rasha, additional, Hauser, Michael A., additional, Heath, Andrew C., additional, Hemmings, Sian M.J., additional, Hougaard, David Michael, additional, Jakovljević, Miro, additional, Jett, Marti, additional, Johnson, Eric Otto, additional, Jones, Ian, additional, Jovanovic, Tanja, additional, Qin, Xue-Jun, additional, Karstoft, Karen-Inge, additional, Kaufman, Milissa L., additional, Kessler, Ronald C., additional, Khan, Alaptagin, additional, Kimbrel, Nathan A., additional, King, Anthony P., additional, Koen, Nastassja, additional, Kranzler, Henry R., additional, Kremen, William S., additional, Lawford, Bruce R., additional, Lebois, Lauren A.M., additional, Lewis, Catrin, additional, Liberzon, Israel, additional, Linnstaedt, Sarah D., additional, Logue, Mark W., additional, Lori, Adriana, additional, Lugonja, Božo, additional, Luykx, Jurjen J., additional, Lyons, Michael J., additional, Maples-Keller, Jessica L., additional, Marmar, Charles, additional, Martin, Nicholas G., additional, Maurer, Douglas, additional, Mavissakalian, Matig R., additional, McFarlane, Alexander, additional, McGlinchey, Regina E., additional, McLaughlin, Katie A., additional, McLean, Samuel A., additional, Mehta, Divya, additional, Mellor, Rebecca, additional, Michopoulos, Vasiliki, additional, Milberg, William, additional, Miller, Mark W., additional, Morris, Charles Phillip, additional, Mors, Ole, additional, Mortensen, Preben B., additional, Nelson, Elliot C., additional, Nordentoft, Merete, additional, Norman, Sonya B., additional, O’Donnell, Meaghan, additional, Orcutt, Holly K., additional, Panizzon, Matthew S., additional, Peters, Edward S., additional, Peterson, Alan L., additional, Peverill, Matthew, additional, Pietrzak, Robert H., additional, Polusny, Melissa A., additional, Rice, John P., additional, Risbrough, Victoria B., additional, Roberts, Andrea L., additional, Rothbaum, Alex O., additional, Rothbaum, Barbara O., additional, Roy-Byrne, Peter, additional, Ruggiero, Kenneth J., additional, Rung, Ariane, additional, Rutten, Bart P.F., additional, Saccone, Nancy L., additional, Sanchez, Sixto E., additional, Schijven, Dick, additional, Seedat, Soraya, additional, Seligowski, Antonia V., additional, Seng, Julia S., additional, Sheerin, Christina M., additional, Silove, Derrick, additional, Smith, Alicia K., additional, Smoller, Jordan W., additional, Sponheim, Scott R., additional, Stein, Dan J., additional, Stevens, Jennifer S., additional, Teicher, Martin H., additional, Thompson, Wesley K., additional, Trapido, Edward, additional, Uddin, Monica, additional, Ursano, Robert J., additional, van den Heuvel, Leigh Luella, additional, Van Hooff, Miranda, additional, Vermetten, Eric, additional, Vinkers, Christiaan H., additional, Voisey, Joanne, additional, Wang, Yunpeng, additional, Wang, Zhewu, additional, Werge, Thomas, additional, Williams, Michelle A., additional, Williamson, Douglas E., additional, Winternitz, Sherry, additional, Wolf, Christiane, additional, Wolf, Erika J., additional, Yehuda, Rachel, additional, Young, Keith A., additional, Young, Ross McD., additional, Zhao, Hongyu, additional, Zoellner, Lori A., additional, Haas, Magali, additional, Lasseter, Heather, additional, Provost, Allison C., additional, Salem, Rany M., additional, Sebat, Jonathan, additional, Shaffer, Richard A., additional, Wu, Tianying, additional, Ripke, Stephan, additional, Daly, Mark J., additional, Ressler, Kerry J., additional, Koenen, Karestan C., additional, Stein, Murray B., additional, and Nievergelt, Caroline M., additional
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- 2022
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47. Embedding digital chronotherapy into bioelectronic medicines
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Fleming, John E., primary, Kremen, Vaclav, additional, Gilron, Ro'ee, additional, Gregg, Nicholas M., additional, Zamora, Mayela, additional, Dijk, Derk-Jan, additional, Starr, Philip A., additional, Worrell, Gregory A., additional, Little, Simon, additional, and Denison, Timothy J., additional
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- 2022
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48. Social-ecological feedbacks drive tipping points in farming system diversification
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Chapman, Melissa, primary, Wiltshire, Serge, additional, Baur, Patrick, additional, Bowles, Timothy, additional, Carlisle, Liz, additional, Castillo, Federico, additional, Esquivel, Kenzo, additional, Gennet, Sasha, additional, Iles, Alastair, additional, Karp, Daniel, additional, Kremen, Claire, additional, Liebert, Jeffrey, additional, Olimpi, Elissa M., additional, Ory, Joanna, additional, Ryan, Matthew, additional, Sciligo, Amber, additional, Thompson, Jennifer, additional, Waterhouse, Hannah, additional, and Boettiger, Carl, additional
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- 2022
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49. Diversified Farming Systems Reduce Nitrous Oxide Emissions and Buffer Irrigation Responses
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Marc William Los Huertos, Céline Pallud, Amber Sciligo, David Gonthier, and Claire Kremen
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- 2022
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50. Associations among executive function Abilities, free Water, and white matter microstructure in early old age
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Daniel E. Gustavson, Derek B. Archer, Jeremy A. Elman, Olivia K. Puckett, Christine Fennema-Notestine, Matthew S. Panizzon, Niranjana Shashikumar, Timothy J. Hohman, Angela L. Jefferson, Lisa T. Eyler, Linda K. McEvoy, Michael J. Lyons, Carol E. Franz, and William S. Kremen
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Adult ,Male ,Aging ,Cognitive Neuroscience ,Neurodegenerative ,Alzheimer's Disease ,Executive control ,Executive Function ,Memory ,Clinical Research ,Behavioral and Social Science ,Acquired Cognitive Impairment ,Humans ,Radiology, Nuclear Medicine and imaging ,Aged ,Abnormal white matter ,Working memory ,Neurosciences ,Water ,Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) ,White Matter ,Brain Disorders ,Diffusion Magnetic Resonance Imaging ,Short-Term ,Neurology ,Cognitive control ,Dementia ,Mental health ,Neurology (clinical) - Abstract
BackgroundStudies have investigated white matter microstructure in relation to late-life cognitive impairments, with fractional anisotropy (FA) and mean diffusivity (MD) measures thought to capture demyelination and axonal degradation. However, new post-processing methods allow isolation of free water (FW), which captures extracellular fluid contributions such as atrophy and neuroinflammation, from tissue components. FW also appears to be highly relevant to late-life cognitive impairment. Here, we evaluated whether executive functions are associated with FW, and FA and MD corrected for FW (FAFWcorr and MDFWcorr).MethodWe examined 489 non-demented men in the Vietnam Era Twin Study of Aging (VETSA) at mean age 68. Two latent factors capturing 'common executive function' and 'working-memory specific' processes were estimated based on 6 tasks. Analyses focused on 11 cortical white matter tracts across three metrics: FW, FAFWcorr, and MDFWcorr.ResultsBetter 'common executive function' was associated with lower FW across 9 of the 11 tracts. There were no significant associations with intracellular metrics after false discovery rate correction. Effects also appeared driven by individuals with MCI (13.7% of the sample). Working memory-specific tasks showed some associations with FAFWcorr, including the triangularis portion of the inferior frontal gyrus. There was no evidence that cognitive reserve (i.e., general cognitive ability assessed in early adulthood) moderated these associations between executive function and FW or FA.DiscussionExecutive function abilities in early old age are associated primarily with extracellular fluid (FW) as opposed to white matter (FAFWcorr or MDFWcorr). Moderation analyses suggested cognitive reserve does not play a strong role in these associations, at least in this sample of non-demented men.
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- 2023
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