27 results on '"Kozielski, Frank"'
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2. Comparison of the pH- and thermally-induced fluctuations of a therapeutic antibody Fab fragment by molecular dynamics simulation
3. Corrigendum to “Design and synthesis of novel thiadiazole-thiazolone hybrids as potential inhibitors of the human mitotic kinesin Eg5 [Bioorg Med Chem Lett 28 (17) (2018) 2930–2938]”
4. Design and synthesis of novel thiadiazole-thiazolone hybrids as potential inhibitors of the human mitotic kinesin Eg5
5. Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors
6. New MKLP-2 inhibitors in the paprotrain series: Design, synthesis and biological evaluations
7. STLC-resistant cell lines as tools to classify chemically divergent Eg5 targeting agents according to their mode of action and target specificity
8. “Snapshots” of Ispinesib-induced Conformational Changes in the Mitotic Kinesin Eg5
9. Doing the methylene shuffle – Further insights into the inhibition of mitotic kinesin Eg5 with S-trityl l-cysteine
10. Inhibition of hepatitis C virus NS5B polymerase by S-trityl-l-cysteine derivatives
11. Elucidating the functionality of kinesins: An overview of small molecule inhibitors
12. Mutations in the human kinesin Eg5 that confer resistance to monastrol and S-trityl-l-cysteine in tumor derived cell lines
13. Synthesis and antiproliferative evaluation of pyrazolo[1,5-a]-1,3,5-triazine myoseverin derivatives
14. New chemical tools for investigating human mitotic kinesin Eg5
15. Structure of Human Eg5 in Complex with a New Monastrol-based Inhibitor Bound in the R Configuration
16. Molecular Dissection of the Inhibitor Binding Pocket of Mitotic Kinesin Eg5 Reveals Mutants that Confer Resistance to Antimitotic Agents
17. S-Trityl-L-cysteine Is a Reversible, Tight Binding Inhibitor of the Human Kinesin Eg5 That Specifically Blocks Mitotic Progression
18. Crystal Structure of the Motor Domain of the Human Kinetochore Protein CENP-E
19. S-Trityl-L-cysteine, a potent inhibitor of the human kinesin motor Eg5, specifically blocks mitotic progression
20. S-trityl-L-cysteine Inhibition of the mitotic kinesin Eg5
21. Crystal Structure of the Motor Domain of the Human Kinetochore Protein CENP-E
22. Automated Analysis of Vapor Diffusion Crystallization Drops with an X-Ray Beam
23. Conformation of the Drosophila Motor Protein Non-claret Disjunctional in Solution from X-ray and Neutron Scattering
24. The Overall Conformation of Conventional Kinesins Studied by Small Angle X-ray and Neutron Scattering
25. The crystal structure of the minus-end-directed microtubule motor protein ncd reveals variable dimer conformations
26. A model of the microtubule–kinesin complex based on electron cryomicroscopy and X-ray crystallography
27. Crystallization and Preliminary X-Ray Analysis of the Single-Headed and Double-Headed Motor Protein Kinesin
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