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Start Over Author "Klein, Katrin" Publisher elsevier bv
8 results on '"Klein, Katrin"'

1. Heterozygous UCHL1 loss-of-function variants cause a neurodegenerative disorder with spasticity, ataxia, neuropathy, and optic atrophy

Author

Park, Joohyun, primary, Tucci, Arianna, additional, Cipriani, Valentina, additional, Demidov, German, additional, Rocca, Clarissa, additional, Senderek, Jan, additional, Butryn, Michaela, additional, Velic, Ana, additional, Lam, Tanya, additional, Galanaki, Evangelia, additional, Cali, Elisa, additional, Vestito, Letizia, additional, Maroofian, Reza, additional, Deininger, Natalie, additional, Rautenberg, Maren, additional, Admard, Jakob, additional, Hahn, Gesa-Astrid, additional, Bartels, Claudius, additional, van Os, Nienke J.H., additional, Horvath, Rita, additional, Chinnery, Patrick F., additional, Tiet, May Yung, additional, Hewamadduma, Channa, additional, Hadjivassiliou, Marios, additional, Downes, Susan M., additional, Németh, Andrea H., additional, Tofaris, George K., additional, Wood, Nicholas W., additional, Hayer, Stefanie N., additional, Bender, Friedemann, additional, Menden, Benita, additional, Cordts, Isabell, additional, Klein, Katrin, additional, Nguyen, Huu Phuc, additional, Krauss, Joachim K., additional, Blahak, Christian, additional, Strom, Tim M., additional, Sturm, Marc, additional, van de Warrenburg, Bart, additional, Lerche, Holger, additional, Maček, Boris, additional, Synofzik, Matthis, additional, Ossowski, Stephan, additional, Timmann, Dagmar, additional, Wolf, Marc E., additional, Smedley, Damian, additional, Riess, Olaf, additional, Schöls, Ludger, additional, Houlden, Henry, additional, Haack, Tobias B., additional, and Hengel, Holger, additional

Published
2023
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2. Heterozygous UCHL1 loss-of-function variants cause a neurodegenerative disorder with spasticity, ataxia, neuropathy, and optic atrophy

Author

Park, Joohyun, primary, Tucci, Arianna, additional, Cipriani, Valentina, additional, Demidov, German, additional, Rocca, Clarissa, additional, Senderek, Jan, additional, Butryn, Michaela, additional, Velic, Ana, additional, Lam, Tanya, additional, Galanaki, Evangelia, additional, Cali, Elisa, additional, Vestito, Letizia, additional, Maroofian, Reza, additional, Deininger, Natalie, additional, Rautenberg, Maren, additional, Admard, Jakob, additional, Hahn, Gesa-Astrid, additional, Bartels, Claudius, additional, van Os, Nienke J.H., additional, Horvath, Rita, additional, Chinnery, Patrick F., additional, Tiet, May Yung, additional, Hewamadduma, Channa, additional, Hadjivassiliou, Marios, additional, Tofaris, George K., additional, Wood, Nicholas W., additional, Hayer, Stefanie N., additional, Bender, Friedemann, additional, Menden, Benita, additional, Cordts, Isabell, additional, Klein, Katrin, additional, Nguyen, Huu Phuc, additional, Krauss, Joachim K., additional, Blahak, Christian, additional, Strom, Tim M., additional, Sturm, Marc, additional, van de Warrenburg, Bart, additional, Lerche, Holger, additional, Maček, Boris, additional, Synofzik, Matthis, additional, Ossowski, Stephan, additional, Timmann, Dagmar, additional, Wolf, Marc E., additional, Smedley, Damian, additional, Riess, Olaf, additional, Schöls, Ludger, additional, Houlden, Henry, additional, Haack, Tobias B., additional, Hengel, Holger, additional, Ambrose, J.C., additional, Arumugam, P., additional, Baple, E.L., additional, Bleda, M., additional, Boardman-Pretty, F., additional, Boissiere, J.M., additional, Boustred, C.R., additional, Brittain, H., additional, Caulfield, M.J., additional, Chan, G.C., additional, Craig, C.E.H., additional, Daugherty, L.C., additional, de Burca, A., additional, Devereau, A., additional, Elgar, G., additional, Foulger, R.E., additional, Fowler, T., additional, Furió-Tarí, P., additional, Hackett, J.M., additional, Halai, D., additional, Hamblin, A., additional, Henderson, S., additional, Holman, J.E., additional, Hubbard, T.J.P., additional, Ibáñez, K., additional, Jackson, R., additional, Jones, L.J., additional, Kasperaviciute, D., additional, Kayikci, M., additional, Lahnstein, L., additional, Lawson, K., additional, Leigh, S.E.A., additional, Leong, I.U.S., additional, Lopez, F.J., additional, Maleady-Crowe, F., additional, Mason, J., additional, McDonagh, E.M., additional, Moutsianas, L., additional, Mueller, M., additional, Murugaesu, N., additional, Need, A.C., additional, Odhams, C.A., additional, Patch, C., additional, Perez-Gil, D., additional, Polychronopoulos, D., additional, Pullinger, J., additional, Rahim, T., additional, Rendon, A., additional, Riesgo-Ferreiro, P., additional, Rogers, T., additional, Ryten, M., additional, Savage, K., additional, Sawant, K., additional, Scott, R.H., additional, Siddiq, A., additional, Sieghart, A., additional, Smedley, D., additional, Smith, K.R., additional, Sosinsky, A., additional, Spooner, W., additional, Stevens, H.E., additional, Stuckey, A., additional, Sultana, R., additional, Thomas, E.R.A., additional, Thompson, S.R., additional, Tregidgo, C., additional, Tucci, A., additional, Walsh, E., additional, Watters, S.A., additional, Welland, M.J., additional, Williams, E., additional, Witkowska, K., additional, Wood, S.M., additional, and Zarowiecki, M., additional

Published
2022
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3. Neutralizing antibody response against the B.1.617.2 (delta) and the B.1.1.529 (omicron) variants after a third mRNA SARS-CoV-2 vaccine dose in kidney transplant recipients

Author

Benning, Louise, primary, Morath, Christian, additional, Bartenschlager, Marie, additional, Kim, Heeyoung, additional, Reineke, Marvin, additional, Beimler, Jörg, additional, Buylaert, Mirabel, additional, Nusshag, Christian, additional, Kälble, Florian, additional, Reichel, Paula, additional, Töllner, Maximilian, additional, Schaier, Matthias, additional, Klein, Katrin, additional, Benes, Vladimir, additional, Rausch, Tobias, additional, Rieger, Susanne, additional, Stich, Maximilian, additional, Tönshoff, Burkhard, additional, Weidner, Niklas, additional, Schnitzler, Paul, additional, Zeier, Martin, additional, Süsal, Caner, additional, Hien Tran, Thuong, additional, Bartenschlager, Ralf, additional, and Speer, Claudius, additional

Published
2022
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4. Neutralizing antibody activity against the B.1.617.2 (delta) variant 8 months after two-dose vaccination with BNT162b2 in health care workers

Author

Benning, Louise, primary, Morath, Christian, additional, Bartenschlager, Marie, additional, Reineke, Marvin, additional, Töllner, Maximilian, additional, Nusshag, Christian, additional, Kälble, Florian, additional, Reichel, Paula, additional, Schaier, Matthias, additional, Klein, Katrin, additional, Schnitzler, Paul, additional, Zeier, Martin, additional, Süsal, Caner, additional, Bartenschlager, Ralf, additional, and Speer, Claudius, additional

Published
2022
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5. Effectiveness of different immunoadsorption columns for anti-A/B antibody depletion

Author

Speer, Claudius, primary, Kälble, Florian, additional, Pego da Silva, Luiza, additional, Nusshag, Christian, additional, Schaier, Matthias, additional, Becker, Luis E., additional, Klein, Katrin, additional, Beimler, Jörg, additional, Sommerer, Claudia, additional, Leo, Albrecht, additional, Süsal, Caner, additional, Mehrabi, Arianeb, additional, Zeier, Martin, additional, and Morath, Christian, additional

Published
2019
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6. Living donor kidney transplantation in patients with donor-specific HLA antibodies enabled by anti-CD20 therapy and peritransplant apheresis

Author

Klein, Katrin, primary, Süsal, Caner, additional, Schäfer, Sebastian M., additional, Becker, Luis Eduardo, additional, Beimler, Jörg, additional, Schwenger, Vedat, additional, Zeier, Martin, additional, Schemmer, Peter, additional, Macher-Goeppinger, Stephan, additional, Scherer, Sabine, additional, Opelz, Gerhard, additional, and Morath, Christian, additional

Published
2013
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8. Neutralizing antibody response against the B.1.617.2 (delta) and the B.1.1.529 (omicron) variants after a third mRNA SARS-CoV-2 vaccine dose in kidney transplant recipients

Author

Louise Benning, Christian Morath, Marie Bartenschlager, Heeyoung Kim, Marvin Reineke, Jörg Beimler, Mirabel Buylaert, Christian Nusshag, Florian Kälble, Paula Reichel, Maximilian Töllner, Matthias Schaier, Katrin Klein, Vladimir Benes, Tobias Rausch, Susanne Rieger, Maximilian Stich, Burkhard Tönshoff, Niklas Weidner, Paul Schnitzler, Martin Zeier, Caner Süsal, Thuong Hien Tran, Ralf Bartenschlager, Claudius Speer, Süsal, Caner (ORCID 0000-0003-2521-8201 & YÖK ID 351800), Benning, Louise, Morath, Christian, Bartenschlager, Marie, Kim, Heeyoung, Reineke, Marvin, Beimler, Jorg, Buylaert, Mirabel, Nusshag, Christian, Kaelble, Florian, Reichel, Paula, Toellner, Maximilian, Schaier, Matthias, Klein, Katrin, Benes, Vladimir, Rausch, Tobias, Rieger, Susanne, Stich, Maximilian, Toenshoff, Burkhard, Weidner, Niklas, Schnitzler, Paul, Zeier, Martin, Tran, Thuong Hien, Bartenschlager, Ralf, Speer, Claudius, Koç University Hospital, and School of Medicine

Subjects
Vaccines, Synthetic, Transplantation, COVID-19 Vaccines, SARS-CoV-2, Clinical decision-making, Clinical research, Immune modulation, Immunosuppression, Kidney transplantation, Nephrology, Practice, Solid organ transplantation, Vaccine, COVID-19, Antibodies, Viral, Antibodies, Neutralizing, Kidney Transplantation, Surgery, Transplant Recipients, Viral Envelope Proteins, Immunoglobulin G, Humans, Immunology and Allergy, Pharmacology (medical), RNA, Messenger, mRNA Vaccines
Abstract

Seroconversion after COVID-19 vaccination is impaired in kidney transplant recipients. Emerging variants of concern such as the B.1.617.2 (delta) and the B.1.1.529 (omicron) variants pose an increasing threat to these patients. In this observational cohort study, we measured anti-S1 IgG, surrogate neutralizing, and anti-receptor-binding domain antibodies three weeks after a third mRNA vaccine dose in 49 kidney transplant recipients and compared results to 25 age-matched healthy controls. In addition, vaccine-induced neutralization of SARS-CoV-2 wild-type, the B.1.617.2 (delta), and the B.1.1.529 (omicron) variants was assessed using a live-virus assay. After a third vaccine dose, anti-S1 IgG, surrogate neutralizing, and anti-receptor-binding domain antibodies were significantly lower in kidney transplant recipients compared to healthy controls. Only 29/49 (59%) sera of kidney transplant recipients contained neutralizing antibodies against the SARS-CoV-2 wild-type or the B.1.617.2 (delta) variant and neutralization titers were significantly reduced compared to healthy controls (p < 0.001). Vaccine-induced cross-neutralization of the B.1.1.529 (omicron) variants was detectable in 15/35 (43%) kidney transplant recipients with seropositivity for anti-S1 IgG, surrogate neutralizing, and/or anti-RBD antibodies. Neutralization of the B.1.1.529 (omicron) variants was significantly reduced compared to neutralization of SARS-CoV-2 wild-type or the B.1.617.2 (delta) variant for both, kidney transplant recipients and healthy controls (p < .001 for all)., Dietmar Hopp Stiftung; Heidelberg Faculty of Medicine Rahel Goitein-Straus Program; Heidelberg Faculty of Medicine Physician Scientist Program; German Federal Research Network Applied Surveillance and Testing (BFAST); Network University Medicine; Helmholtz Association Initiative and Networking Fund Project Virological and Immunological Determinants of COVID-19 Pathogenesis

Published
2022

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