1. Diagnostic utility of new immunoassays for the cardiac markers cTnI, myoglobin and CK-MB mass
- Author
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Matthias Rau, Dragic Bankovic, Katharina Madlener, Christian W. Hamm, Michael Weber, Veselin Mitrovic, and Albrecht Elsaesser
- Subjects
medicine.medical_specialty ,Concordance ,Clinical Biochemistry ,Coronary Disease ,chemistry.chemical_compound ,Troponin T ,Troponin complex ,Internal medicine ,Troponin I ,medicine ,Creatine Kinase, MB Form ,Humans ,Ck mb mass ,Coronary Artery Bypass ,Immunoassay ,biology ,Myoglobin ,business.industry ,General Medicine ,medicine.disease ,Troponin ,chemistry ,Heart failure ,Acute Disease ,Cardiology ,biology.protein ,Reagent Kits, Diagnostic ,business ,Biomarkers - Abstract
Objectives: We investigated the diagnostic value of a new system, the Innotrac Aio!™ immunoassays for troponin, myoglobin and CK-MB, in 270 samples from patients with ACS, after bypass surgery (CABG) or with stable heart failure in comparison to the respective Roche assays. Results: The values of the cardiac markers assessed by the respective assays correlated (cTnT/cTnI Rho = 0.94, myoglobin Rho = 0.87, CK-MB Rho = 0.84). If values were dichotomised, we found a high concordance of test positive and negative classified patients by troponins with the respective assays. Conclusion: There is strong evidence that the Innotrac Aio!™ system for cTnI measurement can be used reliably.
- Published
- 2005
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