Search

The clinicopathologic features of an appendiceal adenocarcinoid that metastasized to the ovary and peritoneum after a 5-year disease-free interval are presented. A review of the literature reveals that appendiceal adenocarcinoid in women has a high frequency (32%) of ovarian metastasis. Among 18 cases with ovarian metastasis, the ovarian metastasis was diagnosed at initial presentation in 13 cases. In the remaining 5 cases the ovarian metastasis developed after disease-free intervals ranging from 6 months to 8 years. In most cases, the ovarian metastasis was the main clinical presentation of the patients. In 5 cases the ovary was the only site of metastasis clinically when metastasis was first diagnosed. There is no known effective treatment for disseminated adenocarcinoid. It is advisable that oophorectomy be included routinely in the initial surgical treatment of appendiceal adenocarcinoid, with the possible exception of the rare pure tubular variant.

An angiomyolipoma arising in the vaginal apex and presenting as a pelvic mass is reported and compared with other reported cases of extrarenal angiomyolipoma. This case appears to be the second case of angiomyolipoma arising in the vaginal wall.

A 54 year old white male died three months after hospitalization for hematemesis and melena due to a duodenal ulcer and two months after the subsequent onset of progressive ascites and edema. At necropsy, lesions characteristic of "lymphomatoid granulomatosis" as delineated by Liebow et al. were found in the liver, retroperitoneal lymph nodes, and mesenteric and retroperitoneal adipose tissue. This case appears to be the first case of "lymphomatoid granulomatosis" confined to the abdomen. This report further broadens the clinical spectrum of the newly delineated "lymphomatoid granulomatosis" and adds another situation to the differential diagnosis of space occupying lesions of the liver.

A case of extragenital malignant mixed müllerian tumor that appeared to represent a second primary tumor in a patient previously treated for disseminated ovarian serous papillary carcinoma is reported and compared with other reported cases of extragenital malignant mixed müllerian tumor.

A 59-year-old woman had carcinosarcoma of the salivary gland. Salivary gland tumors of this type are aggressive and rare. Most patients die of the tumor, but surgical cure has been reported in one case.

The clinicopathologic features of a rare case of hepatic "inflammatory pseudotumor" are described and compared with those of three similar cases reported in the literature. In all four cases symptoms were systemic. The marked reduction in tumor size and the changing cellular composition, from a predominance of fibroblasts to a predominance of histiocytes, confirmed the reactive nature of the lesion in the present case. The etiology is obscure, and the significance of the associated occlusive phlebitis remains to be determined.

The clinicopathologic features of a case of fibroxanthosarcoma of the kidney are reported. This case represents the third reported case in the literature. The nine-year disease-free survival following nephrectomy in this case suggests that this tumor may have a prognosis different from that of the renal cell adenocarcinoma and that reporting of additional cases should be encouraged.

A case of classic (large vessel) polyarteritis nodosa in which the disease was apparently confined in the kidneys is described. The findings in this case support the concept of renal-limited polyarteritis nodosa.