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2. Enzymatic ester hydrolysis and synthesis - two approaches to cycloalkane derivatives of high enantiomeric purity

Author

Ulrich Ader, K. Laumen, Peter Klein, Detlef Breitgoff, and Manfred P. Schneider

Subjects
chemistry.chemical_classification, biology, Chemistry, Stereochemistry, Organic Chemistry, Pseudomonas, Ester hydrolysis, biology.organism_classification, Biochemistry, Cycloalkane, chemistry.chemical_compound, Enzyme, Enzymatic hydrolysis, Drug Discovery, biology.protein, Organic chemistry, Porcine pancreas, Lipase, Enantiomer
Abstract

(1 R ,2 S )- and (1 S ,2 R )-Acetoxycycloalkanedimethanols 1-6 of high enantiomeric purities were prepared by enzymatic hydrolysis and esterification respectively in presence of lipase from porcine pancreas (PPL) and Pseudomonas sp . (SAM-II).

Published
1989

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