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Start Over Author "Jingjue Mao" Publisher elsevier bv
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1. Rapid Fatal Pulmonary Complications in a Chinese Patient After Bortezomib Treatment for ALK-Negative Anaplastic Large-Cell Lymphoma

Author

Xin Zhou, Jingjue Mao, Chao Sun, Jing Wang, and Hongfeng Guo

Subjects
Male, Cancer Research, Bortezomib, Fatal Outcome, Asian People, Ubiquitin, immune system diseases, hemic and lymphatic diseases, medicine, Humans, ALK-Negative Anaplastic Large Cell Lymphoma, cardiovascular diseases, Enzyme Inhibitors, Adverse effect, Lung, neoplasms, Aged, biology, business.industry, Hematology, medicine.disease, Boronic Acids, Lymphoma, Oncology, Proteasome, Hematologic Neoplasms, Pyrazines, biology.protein, Proteasome inhibitor, Cancer research, Lymphoma, Large-Cell, Anaplastic, Lymphoma, Large B-Cell, Diffuse, business, medicine.drug
Abstract

Bortezomib, a reversible proteasome inhibitor, is used for the treatment of hematologic malignancies. Common adverse events with bortezomib include gastrointestinal symptoms, thrombocytopenia, and neuropathy, whereas severe pulmonary complications have been rarely described. Herein, we present a case of rapid fatal pulmonary complications in a patient with ALK-negative anaplastic large-cell lymphoma after receiving a treatment with bortezomib.

Published
2010

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