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Your search keyword '"Jaafar Hasnan"' showing total 11 results
Start Over Author "Jaafar Hasnan" Publisher elsevier bv
11 results on '"Jaafar Hasnan"'

2. Differential expression of entorhinal cortex and hippocampal subfields α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and N-methyl-D-aspartate (NMDA) receptors enhanced learning and memory of rats following administration of Centella asiatica

Author

Wong, Jia Hui, primary, Muthuraju, Sangu, additional, Reza, Faruque, additional, Senik, Mohd Harizal, additional, Zhang, Jingli, additional, Mohd Yusuf Yeo, Nor Aqilah Binti, additional, Chuang, Huei Gau, additional, Jaafar, Hasnan, additional, Yusof, Siti Rafidah, additional, Mohamad, Habsah, additional, Tengku Muhammad, Tengku Sifzizul, additional, Ismail, Nor Hadiani, additional, Husin, Siti Sarwana, additional, and Abdullah, Jafri Malin, additional

Published
2019
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3. Human tuberculosis brain promotes neuronal apoptosis but not in astrocytes with high expression of vascular endothelial growth factor

Author

Othman, Fatihah N., primary, Muthuraju, Sangu, additional, Noor, Siti Suraiya M., additional, Abdullah, Sarimah, additional, Mohd Yusoff, Abdul Aziz, additional, Tharakan, John, additional, Bhaskar, Shalini, additional, Mahmood, Mohd Shah, additional, Kassim, Fauziah, additional, Rafia, Hanip, additional, Mohd Haspani, Mohd Saffari, additional, Alias, Azmi, additional, Pando, Rogelio H., additional, Abdullah, Jafri M., additional, and Jaafar, Hasnan, additional

Published
2018
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4. Histopathological studies of cardiac lesions after long term administration of Methamphetamine in high dosage – Part II

Author

Khan Jesmine, Arthur Kong Sn Molh, Jaafar Hasnan, and Mohammed Nasimul Islam

Subjects
Male, Placebo, Euphoriant, Drug Administration Schedule, Methamphetamine, Pathology and Forensic Medicine, Muscle hypertrophy, Forensic Toxicology, Atrophy, Fibrosis, Edema, medicine, Animals, Rats, Wistar, Forensic Pathology, Microscopy, Dose-Response Relationship, Drug, business.industry, Myocardium, Granulation tissue, Heart, Hypertrophy, medicine.disease, Rats, Eosinophils, Issues, ethics and legal aspects, medicine.anatomical_structure, Anesthesia, Vacuoles, Granulation Tissue, Central Nervous System Stimulants, medicine.symptom, business, Injections, Intraperitoneal, medicine.drug
Abstract

A small amount of Methamphetamine (MA) can produce behavioural changes such as euphoria, increased alertness, paranoia, decreased appetite and increased physical activity. In cardiovascular system, it can produce chest pain and hypertension which can result in cardiovascular collapse. In addition, MA causes accelerated heartbeat, elevated blood pressure. It can also cause irreversible damage to blood vessels in the brain. A number of sympathomimetic amines are capable of causing myocardial damage, but the cardio-toxic action of MA has been of particular interest since standardized dosage consistently produces myocardial lesions. As this drug is a choice of many teenagers and young adults, the damage to their health, as well as their future aspects could be greatly affected, therefore more evidence must be sought to convince them the negative root and show them the optimism of recovery and salvation. To clarify the effect of Methamphetamine (MA) on myocardium, 56 male Wister rats aged four weeks were divided equally into MA, Methamphetamine withdrawal (MW), Placebo (P) and Control (C) group were examined following daily intra-peritoneal administration of MA at a dose of 5 mg/kg body weight for 2, 4, 8 and 12 weeks. Normal saline was similarly injected in P group. Light microscopic changes was seen in the myocardium of MA treated group including eosinophilic degeneration, atrophy, hypertrophy, disarray, edema, cellular infiltration, myolysis, granulation tissue, fibrosis and vacuolization. On the other hand, the withdrawal group showed evidence of gradual recovery of those myocardial changes. Optimism is therefore generated about possibility of returning towards normal by withdrawing of this drug by the addicts.

Published
2009
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5. Mouse model of intracerebellar haemorrhage

Author

Tijjani Salihu, Abubakar, primary, Muthuraju, Sangu, additional, Aziz Mohamed Yusoff, Abdul, additional, Ahmad, Farizan, additional, Zulkifli Mustafa, Mohd, additional, Jaafar, Hasnan, additional, Idris, Zamzuri, additional, Rahman Izaini Ghani, Abdul, additional, and Malin Abdullah, Jafri, additional

Published
2016
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