1. Recurrent laryngeal papillomatosis with oesophageal involvement in a 2 year old boy: Successful treatment with the quadrivalent human papillomatosis vaccine
- Author
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Gábor Katona, Anikó Nagy, Zsófia Mészner, Imre Gerlinger, and István Jankovics
- Subjects
Male ,medicine.medical_specialty ,Recurrent laryngeal papillomatosis ,Papillomatosis ,Childhood immunization ,medicine ,Humans ,Papillomavirus Vaccines ,Surgical treatment ,Laryngeal Neoplasms ,Human papilloma virus ,Papilloma ,Human papillomavirus 11 ,business.industry ,Papillomavirus Infections ,General Medicine ,Human papillomavirus 6 ,Dermatology ,Surgery ,Vaccination ,Otorhinolaryngology ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Neoplasm Recurrence, Local ,medicine.symptom ,Recurrent Respiratory Papillomatosis ,business - Abstract
Authors present a case report of a 2-year-old boy with recurrent laryngeal papillomatosis with oesophageal involvement due to human papilloma virus types 6 and 11, who needed surgical treatment every 4-6 weeks, altogether 11 times. After detailed immunological evaluation of basic immunological parameters, and in vitro detection of good responses to routine childhood immunization, a therapeutic vaccination has been decided with a 4-valent HPV vaccine. Following the third vaccine dose both laryngeal and oesophageal lesions disappeared completely, and for 2 years follow-up no papillomas could be detected. Vaccination could be a promising method in the treatment of RRP in children.
- Published
- 2015
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