51 results on '"Isacson, O"'
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2. Gene therapy by proteasome activator, PA28γ, improves motor coordination and proteasome function in Huntington’s disease YAC128 mice
3. In vivo modeling of neuronal function, axonal impairment and connectivity in neurodegenerative and neuropsychiatric disorders using induced pluripotent stem cells
4. 1.2.2 USING STEM CELLS AND IPS CELLS TO DISCOVER NEW TREATMENTS FOR PARKINSON'S DISEASE
5. O.106 Post-mortem analyses of fetal transplants of dopamine neurons in Parkinson's disease patients reveal no or minimal pathology
6. Enhanced binding of metabotropic glutamate receptor type 5 (mGluR5) PET tracers in the brain of parkinsonian primates
7. Influence of cell preparation and target location on the behavioral recovery after striatal transplantation of fetal dopaminergic neurons in a primate model of Parkinson’s disease
8. A tyrosine hydroxylase–yellow fluorescent protein knock-in reporter system labeling dopaminergic neurons reveals potential regulatory role for the first intron of the rodent tyrosine hydroxylase gene
9. Insights into Parkinson's disease models and neurotoxicity using non-invasive imaging
10. S.16.01 Designing stem cells as therapeutic agents inneurological disease
11. Functional Imaging of the Dopamine System: In Vivo Evaluation of Dopamine Deficiency and Restoration
12. Alzheimer's disease and Down's syndrome: roles of APP, trophic factors and ACh
13. Parkinsonian Motor Deficits Are Reflected by Proportional A9/A10 Dopamine Neuron Degeneration in the Rat
14. Cell implantation therapies for Parkinson's disease using neural stem, transgenic or xenogeneic donor cells
15. Enhanced axonal growth from fetal human bcl-2 transgenic mouse dopamine neurons transplanted to the adult rat striatum
16. Neuroimmunophilin ligand enhances neurite outgrowth and effect of fetal dopamine transplants
17. Dopamine imaging markers and predictive mathematical models for progressive degeneration in Parkinson's disease
18. A Novel Immunophilin Ligand: Distinct Branching Effects on Dopaminergic Neurons in Culture and Neurotrophic Actions after Oral Administration in an Animal Model of Parkinson's Disease
19. Neural transplantation studies reveal the brain's capacity for continuous reconstruction
20. Specific axon guidance factors persist in the adult brain as demonstrated by pig neuroblasts transplanted to the rat
21. The neurobiological and clinical potential of neural cell transplantation: Special issue based on the meeting of the american society for neural transplantation, 1995
22. A novel mode of immunoprotection of neural xenotransplants: Masking of donor major histocompatibility complex class I enhances transplant survival in the central nervous system
23. Selective putaminal excitotoxic lesions in non-human primates model the movement disorder of Huntington disease
24. The lateral ganglionic eminence is the origin of cells committed to striatal phenotypes: neural transplantation and developmental evidence
25. Cytoarchitectonic Development, Axon-Glia Relationships, and Long Distance Axon Growth of Porcine Striatal Xenografts in Rats
26. Neural xenotransplantation: Reconstruction of neuronal circuitry across species barriers
27. Elevation of neuronal MAO-B activity in a transgenic mouse model does not increase sensitivity to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
28. Implanted NGF-Producing Fibroblasts Induce Catalase and Modify ATP Levels but Do Not Affect Glutamate Receptor Binding or NMDA Receptor Expression in the Rat Striatum
29. On neuronal health
30. Glutamate Receptor Binding Sites in MPTP-Treated Mice
31. Magnetic resonance imaging to monitor pathology of caudate-putamen after excitotoxin-induced neuronal loss in the nonhuman primate brain
32. Neuronal loss or replacement in the injured adult cerebral neocortex induces extensive remodeling of intrinsic and afferent neural systems
33. 6-[18F]fluoro-l-dopa uptake and [76Br]bromolisuride binding in the excitotoxically lesioned caudate-putamen of nonhuman primates studied using positron emission tomography
34. Excitotoxic lesions of the rat entorhinal cortex. Effects of selective neuronal damage on acquisition and retention of a non-spatial reference memory task
35. Intracerebral implantation of nerve growth factor-producing fibroblasts protects striatum against neurotoxic levels of excitatory amino acids
36. A primate model of Huntington's disease: Behavioral and anatomical studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon
37. Loss of true blue labelling from the medial septum following transection of the fimbria-fornix: evidence for the death of cholinergic and non-cholinergic neurons
38. Cortical grafts prevent atrophy of cholinergic basal nucleus neurons induced by excitotoxic cortical damage
39. In vivo measurement of spontaneous release and metabolism of dopamine from intrastriatal nigral grafts using intracerebral dialysis
40. Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum—I. Subcortical afferents
41. Astroglial response in the excitotoxically lesioned neostriatum and its projection areas in the rat
42. Effects of dopamine-rich grafts on conditioned rotation in rats with unilateral 6-hydroxydopamine lesions
43. Neural grafting in a rat model of huntington's disease: Progressive neurochemical changes after neostriatal ibotenate lesions and striatal tissue grafting
44. Striatal grafts in rats with unilateral neostriatal lesions—I. Ultrastructural evidence of afferent synaptic inputs from the host nigrostriatal pathway
45. Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum—III. Efferent projecting graft neurons and their relation to host afferents within the grafts
46. Nerve growth factor receptor immunoreactivity in the rat suprachiasmatic nucleus
47. Presence of Schwann cells in neurodegenerative lesions of the central nervous system
48. Striatal grafts in rats with unilateral neostriatal lesions—III. Recovery from dopamine-dependent motor asymmetry and deficits in skilled paw reaching
49. Loss of transmitter-associated enzyme staining following axotomy does not indicate death of brainstem cholinergic neurons
50. Striatal grafts in rats with unilateral neostriatal lesions—II. In vivo monitoring of gaba release in globus pallidus and substantia nigra
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