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Your search keyword '"Hu, Mengyun"' showing total 14 results
Start Over Author "Hu, Mengyun" Publisher elsevier bv
14 results on '"Hu, Mengyun"'

5. Multi-omics analysis of mucosal and systemic immunity to SARS-CoV-2 after birth

Author

Wimmers, Florian, primary, Burrell, Allison R., additional, Feng, Yupeng, additional, Zheng, Hong, additional, Arunachalam, Prabhu S., additional, Hu, Mengyun, additional, Spranger, Sara, additional, Nyhoff, Lindsay E., additional, Joshi, Devyani, additional, Trisal, Meera, additional, Awasthi, Mayanka, additional, Bellusci, Lorenza, additional, Ashraf, Usama, additional, Kowli, Sangeeta, additional, Konvinse, Katherine C., additional, Yang, Emily, additional, Blanco, Michael, additional, Pellegrini, Kathryn, additional, Tharp, Gregory, additional, Hagan, Thomas, additional, Chinthrajah, R. Sharon, additional, Nguyen, Tran T., additional, Grifoni, Alba, additional, Sette, Alessandro, additional, Nadeau, Kari C., additional, Haslam, David B., additional, Bosinger, Steven E., additional, Wrammert, Jens, additional, Maecker, Holden T., additional, Utz, Paul J., additional, Wang, Taia T., additional, Khurana, Surender, additional, Khatri, Purvesh, additional, Staat, Mary A., additional, and Pulendran, Bali, additional

Published
2023
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8. Durability of immune responses to the BNT162b2 mRNA vaccine

Author

Suthar, Mehul S., primary, Arunachalam, Prabhu S., additional, Hu, Mengyun, additional, Reis, Noah, additional, Trisal, Meera, additional, Raeber, Olivia, additional, Chinthrajah, Sharon, additional, Davis-Gardner, Meredith E., additional, Manning, Kelly, additional, Mudvari, Prakriti, additional, Boritz, Eli, additional, Godbole, Sucheta, additional, Henry, Amy R., additional, Douek, Daniel C., additional, Halfmann, Peter, additional, Kawaoka, Yoshihiro, additional, Boyd, Scott D., additional, Davis, Mark M., additional, Zarnitsyna, Veronika I., additional, Nadeau, Kari, additional, and Pulendran, Bali, additional

Published
2022
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10. Efficient and selective oxidation of secondary benzylic C H bonds to ketones with O2 catalyzed by metalloporphyrins under solvent-free and additive-free conditions

Author

Hu Mengyun, Ye Hongliang, Bei Qi, Yuan-Bin She, Lei Liu, and Hai-Min Shen

Subjects
Solvent free, 010405 organic chemistry, Chemistry, Process Chemistry and Technology, Substrate (chemistry), chemistry.chemical_element, 010402 general chemistry, 01 natural sciences, Combinatorial chemistry, Oxygen, Catalysis, 0104 chemical sciences, Metal, Electron transfer, visual_art, visual_art.visual_art_medium, Surface modification, Physical and Theoretical Chemistry, Selectivity
Abstract

Non-solvent and non-additive oxidation of secondary benzylic C–H bonds to aromatic ketones utilizing simple metalloporphyrins as catalysts and O2 was investigated systematically. Based on systematical studies on reaction parameters, such as the structures of porphyrins, the types of central metals, the amount of catalyst, the pressure of oxygen, and the temperature, most aromatics with secondary benzylic C–H had been converted efficiently and selectively to their corresponding aromatic ketones catalyzed by the optimized metalloporphyrin catalyst T(2,3,6-triCl)PPCo. And the selectivity towards aromatic ketones reached up to 80 %–95 % with acceptable conversions in lower catalyst-loading (2.4 × 10−3%, mol/mol). The highest selectivity was achieved for substrate 1,2,3,4-tetrahydronaphthalene with the selectivity of 95.0 % in the conversion of 46.3 %. The superior catalytic performance of T(2,3,6-triCl)PPCo could be mainly ascribed to its excellent plane structure, superior ability for electron transfer and low positive charge around the central metal. All of above properties promoted the formation of catalytic active species high-valence cobalt-oxo complexes, and facilitated the approach of substrates to the catalytic active centers. This work presented an optimized balance among higher selectivity, milder conditions, lower catalyst-loading, and simpler catalysts compared with current documents, which was not only an efficient, practical and significant strategy to functionalize the widely available aromatics possessing secondary benzylic C H with high efficiency and selectivity under milder conditions, but also an important instance in the effective functionalization and utilization of other C H bonds employing optimized catalytic systems based on metalloporphyrins.

Published
2020

11. Efficient and selective oxidation of tertiary benzylic C H bonds with O2 catalyzed by metalloporphyrins under mild and solvent-free conditions

Author

Bei Qi, Ye Hongliang, Yuan-Bin She, Lei Liu, Hai-Min Shen, and Hu Mengyun

Subjects
Cumene, Autoxidation, 010405 organic chemistry, Chemistry, Process Chemistry and Technology, Substituent, Alcohol, 010402 general chemistry, 01 natural sciences, Porphyrin, Medicinal chemistry, Catalysis, 0104 chemical sciences, Metal, chemistry.chemical_compound, visual_art, visual_art.visual_art_medium, Selectivity
Abstract

The direct and efficient oxidation of tertiary benzylic C H bonds to alcohols with O2 was accomplished in the presence of metalloporphyrins as catalysts under solvent-free and additive-free conditions. Based on effective inhibition on the unselective autoxidation and deep oxidation, systematical investigation on the effects of porphyrin ligands and metal centers, and apparent kinetics study, the oxidation system employing porphyrin manganese(II) (T(2,3,6-triCl)PPMn) with bulkier substituents as catalyst, was regarded as the most promising and efficient one. For the typical substrate, the conversion of cumene could reach up to 57.6% with the selectivity of 70.5% toward alcohol, both of them being higher than the current documents under similar conditions. The superiority of T(2,3,6-triCl)PPMn was mainly attributed to its bulkier substituent groups preventing metalloporphyrins from oxidative degradation, its planar structure favoring the interaction between central metal with reactants, and the high efficiency of Mn(II) in the catalytic transformation of hydroperoxides to alcohols.

Published
2020

13. Bronchial epithelial cell extracellular vesicles ameliorate epithelial–mesenchymal transition in COPD pathogenesis by alleviating M2 macrophage polarization

Author

He, Shengyang, primary, Chen, Duanni, additional, Hu, Mengyun, additional, Zhang, Li, additional, Liu, Caihong, additional, Traini, Daniela, additional, Grau, Georges E., additional, Zeng, Zhengpeng, additional, Lu, Junjuan, additional, Zhou, Guanzhi, additional, Xie, Lihua, additional, and Sun, Shenghua, additional

Published
2019
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