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19 results on '"Hofmeijer J"'

3. MRI factors associated with cognitive functioning after acute onset brain injury: Systematic review and meta-analysis

Author

Verhulst, M.M.L.H., Glimmerveen, A.B., Heugten, C.M. van, Helmich, R.C.G., and Hofmeijer, J.

Subjects
240 Systems Neurology, All institutes and research themes of the Radboud University Medical Center, Neurology, Cognitive Neuroscience, Radiology, Nuclear Medicine and imaging, Neurology (clinical), Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3]
Abstract

Contains fulltext : 294200.pdf (Publisher’s version ) (Open Access) Impairments of memory, attention, and executive functioning are frequently reported after acute onset brain injury. MRI markers hold potential to contribute to identification of patients at risk for cognitive impairments and clarification of mechanisms. The aim of this systematic review was to summarize and value the evidence on MRI markers of memory, attention, and executive functioning after acute onset brain injury. We included ninety-eight studies, on six classes of MRI factors (location and severity of damage (n = 15), volume/atrophy (n = 36), signs of small vessel disease (n = 15), diffusion-weighted imaging measures (n = 36), resting-state functional MRI measures (n = 13), and arterial spin labeling measures (n = 1)). Three measures showed consistent results regarding their association with cognition. Smaller hippocampal volume was associated with worse memory in fourteen studies (pooled correlation 0.58 [95% CI: 0.46-0.68] for whole, 0.11 [95% CI: 0.04-0.19] for left, and 0.34 [95% CI: 0.17-0.49] for right hippocampus). Lower fractional anisotropy in cingulum and fornix was associated with worse memory in six and five studies (pooled correlation 0.20 [95% CI: 0.08-0.32] and 0.29 [95% CI: 0.20-0.37], respectively). Lower functional connectivity within the default-mode network was associated with worse cognition in four studies. In conclusion, hippocampal volume, fractional anisotropy in cingulum and fornix, and functional connectivity within the default-mode network showed consistent associations with cognitive performance in all types of acute onset brain injury. External validation and cut off values for predicting cognitive impairments are needed for clinical implementation.

Published
2023

7. Risk factors for atherosclerotic and medial arterial calcification of the intracranial internal carotid artery

Author

Vos, Annelotte, primary, Kockelkoren, Remko, additional, de Vis, Jill B., additional, van der Schouw, Yvonne T., additional, van der Schaaf, Irene C., additional, Velthuis, Birgitta K., additional, Mali, Willem P.T.M., additional, de Jong, Pim A., additional, Majoie, C.B., additional, Roos, Y.B., additional, Duijm, L.E., additional, Keizer, K., additional, van der Lugt, A., additional, Dippel, D.W., additional, Droogh-de Greve, K.E., additional, Bienfait, H.P., additional, van Walderveen, M.A., additional, Wermer, M.J.H., additional, Lycklama à Nijeholt, G.J., additional, Boiten, J., additional, Duyndam, D., additional, Kwa, V.I., additional, Meijer, F.J., additional, van Dijk, E.J., additional, Kesselring, F.O., additional, Hofmeijer, J., additional, Vos, J.A., additional, Schonewille, W.J., additional, van Rooij, W.J., additional, de Kort, P.L., additional, Pleiter, C.C., additional, Bakker, S.L., additional, Bot, J., additional, Visser, M.C., additional, Velthuis, B.K., additional, van der Schaaf, I.C., additional, Dankbaar, J.W., additional, Mali, W.P., additional, van Seeters, T., additional, Horsch, A.D., additional, Niesten, J.M., additional, Biessels, G.J., additional, Kappelle, L.J., additional, Luitse, M.J., additional, and van der Graaf, Y., additional

Published
2018
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