55 results on '"Hobbs, Helen H."'
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2. Hepatic TM6SF2 Is Required for Lipidation of VLDL in a Pre-Golgi Compartment in Mice and Rats
3. Missense variant in insulin receptor (Y1355H) segregates in family with fatty liver disease
4. Angiopoietin-like protein 3 governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance
5. Patatin-like phospholipase domain–containing protein 3 promotes transfers of essential fatty acids from triglycerides to phospholipids in hepatic lipid droplets
6. Patatin-like phospholipase domain–containing protein 3 promotes transfers of essential fatty acids from triglycerides to phospholipids in hepatic lipid droplets
7. ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance
8. Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins
9. Adult-onset liver disease and hepatocellular carcinoma in S-adenosylhomocysteine hydrolase deficiency
10. Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion
11. ANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys
12. Relative roles of ABCG5/ABCG8 in liver and intestine
13. ANGPTL8/Betatrophin Does Not Control Pancreatic Beta Cell Expansion
14. APOC3, Coronary Disease, and Complexities of Mendelian Randomization
15. Molecular characterization of proprotein convertase subtilisin/kexin type 9-mediated degradation of the LDLR
16. Expression and Characterization of a PNPLA3 Protein Isoform (I148M) Associated with Nonalcoholic Fatty Liver Disease
17. Sequences in the Nonconsensus Nucleotide-binding Domain of ABCG5/ABCG8 Required for Sterol Transport
18. A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis
19. Genetic Variation in ANGPTL4 Provides Insights into Protein Processing and Function
20. PCSK9: a convertase that coordinates LDL catabolism
21. Binding of Proprotein Convertase Subtilisin/Kexin Type 9 to Epidermal Growth Factor-like Repeat A of Low Density Lipoprotein Receptor Decreases Receptor Recycling and Increases Degradation
22. Sterol Intermediates from Cholesterol Biosynthetic Pathway as Liver X Receptor Ligands
23. Molecular Characterization of Loss-of-Function Mutations in PCSK9 and Identification of a Compound Heterozygote
24. Sterol Transfer by ABCG5 and ABCG8
25. A Spectrum of PCSK9 Alleles Contributes to Plasma Levels of Low-Density Lipoprotein Cholesterol
26. Functional Asymmetry of Nucleotide-binding Domains in ABCG5 and ABCG8
27. The Modular Adaptor Protein Autosomal Recessive Hypercholesterolemia (ARH) Promotes Low Density Lipoprotein Receptor Clustering into Clathrin-coated Pits
28. A phylogenetic survey of biliary lipids in vertebrates ,
29. Ezetimibe normalizes metabolic defects in mice lacking ABCG5 and ABCG8
30. ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bile
31. Expression of ABCG5 and ABCG8 Is Required for Regulation of Biliary Cholesterol Secretion
32. African Americans and Caucasians have a similar prevalence of coronary calcium in the Dallas Heart Study
33. High-level expression of ABCG5 and ABCG8 attenuates diet-induced hypercholesterolemia and atherosclerosis in Ldlr−− mice
34. The Modular Adaptor Protein ARH Is Required for Low Density Lipoprotein (LDL) Binding and Internalization but Not for LDL Receptor Clustering in Coated Pits
35. Missense Mutations in ABCG5 and ABCG8 Disrupt Heterodimerization and Trafficking
36. The Dallas Heart Study: a population-based probability sample for the multidisciplinary study of ethnic differences in cardiovascular health
37. Selective sterol accumulation in ABCG5/ABCG8-deficient mice
38. ABCG5 and ABCG8 Are Obligate Heterodimers for Protein Trafficking and Biliary Cholesterol Excretion
39. Normal Sorting but Defective Endocytosis of the Low Density Lipoprotein Receptor in Mice with Autosomal Recessive Hypercholesterolemia
40. Stimulation of Cholesterol Excretion by the Liver X Receptor Agonist Requires ATP-binding Cassette Transporters G5 and G8
41. ARH Is a Modular Adaptor Protein That Interacts with the LDL Receptor, Clathrin, and AP-2
42. ARH mutations and hypercholesterolaemia in Sardinia
43. Autosomal recessive hypercholesterolaemia in Sardinia, Italy, and mutations in ARH: a clinical and molecular genetic analysis
44. Heritability of plasma noncholesterol sterols and relationship to DNA sequence polymorphism in ABCG5 and ABCG8
45. Determinants of human apolipoprotein [a] secretion from mouse hepatocyte cultures
46. Transport of Lipids from High and Low Density Lipoproteins via Scavenger Receptor-BI
47. Polyunsaturated fatty acids up-regulate hepatic scavenger receptor B1 (SR-BI) expression and HDL cholesteryl ester uptake in the hamster
48. Transgenic mice expressing a human apolipoprotein[a] allele
49. Scavenger Receptor, Class B, Type I-dependent Stimulation of Cholesterol Esterification by High Density Lipoproteins, Low Density Lipoproteins, and Nonlipoprotein Cholesterol
50. Kinetic characteristics and regulation of HDL cholesteryl ester and apolipoprotein transport in the apoA-I-/- mouse
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