59 results on '"Helin, Kristian"'
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2. 3151 – THE ALTERNATIVE NUCLEOSOME REMODELING FACTOR COMPLEX SUSTAINS ACUTE MYELOID LEUKEMIA BY REGULATING THE ACCESSIBILITY OF INSULATOR REGIONS
3. Chromatin modifier HUSH co-operates with RNA decay factor NEXT to restrict transposable element expression
4. CpG island reconfiguration for the establishment and synchronization of polycomb functions upon exit from naive pluripotency
5. SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
6. Generation of locus-specific degradable tag knock-ins in mouse and human cell lines
7. Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis
8. Quantification of Differential Transcription Factor Activity and Multiomics-Based Classification into Activators and Repressors: diffTF
9. A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2
10. Non-core Subunits of the PRC2 Complex Are Collectively Required for Its Target-Site Specificity
11. Molecular Mechanisms Directing PRC2 Recruitment and H3K27 Methylation
12. Quantification of Differential Transcription Factor Activity and Multiomics-Based Classification into Activators and Repressors: DiffTF
13. The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery
14. The PRC2 component JARID2 is dispensable for hematopoietic stem cells, but critical for maintenance of leukemic stem cells
15. Systems Level Analysis of Histone H3 Post-translational Modifications (PTMs) Reveals Features of PTM Crosstalk in Chromatin Regulation
16. A Dual Program for Translation Regulation in Cellular Proliferation and Differentiation
17. Gene Silencing Triggers Polycomb Repressive Complex 2 Recruitment to CpG Islands Genome Wide
18. Chromatin Repressive Complexes in Stem Cells, Development, and Cancer
19. Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome
20. Cell cycle, differentiation and disease
21. Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas
22. CHD5 Is Required for Neurogenesis and Has a Dual Role in Facilitating Gene Expression and Polycomb Gene Repression
23. The Histone Demethylase PHF8 Governs Retinoic Acid Response in Acute Promyelocytic Leukemia
24. Fbxl10/Kdm2b Recruits Polycomb Repressive Complex 1 to CpG Islands and Regulates H2A Ubiquitylation
25. Tet Proteins Connect the O-Linked N-acetylglucosamine Transferase Ogt to Chromatin in Embryonic Stem Cells
26. Tet2 Facilitates the Derepression of Myeloid Target Genes during CEBPα-Induced Transdifferentiation of Pre-B Cells
27. Hypermethylated in Cancer 1 (HIC1) Recruits Polycomb Repressive Complex 2 (PRC2) to a Subset of Its Target Genes through Interaction with Human Polycomb-like (hPCL) Proteins
28. A New Role for the Polycomb Group Protein Ezh1 in Promoting Transcription
29. Inhibitors of histone demethylases
30. Histone demethylases in development and disease
31. Polycomb Group Protein Displacement and Gene Activation through MSK-Dependent H3K27me3S28 Phosphorylation
32. Polycomb group protein-mediated repression of transcription
33. Quantitative Mass Spectrometry of Histones H3.2 and H3.3 in Suz12-deficient Mouse Embryonic Stem Cells Reveals Distinct, Dynamic Post-translational Modifications at Lys-27 and Lys-36
34. Histone methyltransferases in cancer
35. A Functional Link between the Histone Demethylase PHF8 and the Transcription Factor ZNF711 in X-Linked Mental Retardation
36. Human CDT1 Associates with CDC7 and Recruits CDC45 to Chromatin during S Phase
37. The emerging functions of histone demethylases
38. Role of the Polycomb Repressive Complex 2 in Acute Promyelocytic Leukemia
39. RBP2 Belongs to a Family of Demethylases, Specific for Tri-and Dimethylated Lysine 4 on Histone 3
40. Human TFDP3, a Novel DP Protein, Inhibits DNA Binding and Transactivation by E2F
41. HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity
42. The Ubiquitin Ligase HectH9 Regulates Transcriptional Activation by Myc and Is Essential for Tumor Cell Proliferation
43. A Novel Repressive E2F6 Complex Containing the Polycomb Group Protein, EPC1, That Interacts with EZH2 in a Proliferation-specific Manner
44. E2F target genes: unraveling the biology
45. Naturally death-resistant precursor cells revealed as the origin of retinoblastoma
46. Loss of MYC Confers Resistance to Doxorubicin-induced Apoptosis by Preventing the Activation of Multiple Serine Protease- and Caspase-mediated Pathways
47. Identification of Target Genes of the p16INK4A-pRB-E2F Pathway
48. Profiling cancer
49. DcE2F, a Functional Plant E2F-like Transcriptional Activator from Daucus carota
50. E2F Family Members Are Differentially Regulated by Reversible Acetylation
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