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Your search keyword '"Guillemot, F"' showing total 26 results
Start Over Author "Guillemot, F" Publisher elsevier bv
26 results on '"Guillemot, F"'

2. Gastrite lymphocytaire et maladie de Ménétrier : une ou deux maladies ?

Author

J.-F. Colombel, Guillemot F, Emmanuelle Leteurtre, David Buob, Samira Hafraoui, Agnès Wacrenier, Christophe Mariette, and Vincent Maunoury

Subjects
medicine.medical_specialty, business.industry, Gastroenterology, MEDLINE, Medicine, General Medicine, Gastritis, medicine.symptom, business, Dermatology
Published
2009

3. O69 ALBUMIN INFUSION FOR BACTERIAL INFECTIONS OTHER THAN SPONTANEOUS BACTERIAL PERITONITIS IN CIRRHOTIC PATIENTS: A MULTICENTER RANDOMIZED CONTROLLED STUDY (ALB-CIRINF STUDY)

Author

Thévenot, T., primary, Bureau, C., additional, Oberti, F., additional, Anty, R., additional, Louvet, A., additional, Plessier, A., additional, Rudler, M., additional, Heurgué-Berlot, A., additional, Rosa, I., additional, Talbodec, N., additional, Dao, T., additional, Ozenne, V., additional, Carbonell, N., additional, Causse, X., additional, Goria, O., additional, Minello, A., additional, De Ledinghen, V., additional, Amathieu, R., additional, Barraud, H., additional, Nguyen-Khac, E., additional, Becker, C., additional, Paupard, T., additional, Botta-Fridlung, D., additional, Abdelli, N., additional, Guillemot, F., additional, Monnet, E., additional, and Di Martino, V., additional

Published
2014
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26. Mapping the Global Chromatin Connectivity Network for Sox2 Function in Neural Stem Cell Maintenance

Author

Menno P. Creyghton, Silvia K. Nicolis, Federico Zambelli, Yanfen Zhu, Paul Robson, Rebecca Favaro, Jessica Bertolini, Ben Martynoga, Paola Bovolenta, Marcos J. Cardozo, Chee Hong Wong, Noemi Tabanera, Sergio Ottolenghi, Cristiana Barone, Giulio Pavesi, Chew Yee Ngan, Chia-Lin Wei, Marit W. Vermunt, Harianto Tjong, Sara Mercurio, Miriam Pagin, Jessica Mariani, François Guillemot, Bertolini, J, Favaro, R, Zhu, Y, Pagin, M, Ngan, C, Wong, C, Tjong, H, Vermunt, M, Martynoga, B, Barone, C, Mariani, J, Cardozo, M, Tabanera, N, Zambelli, F, Mercurio, S, Ottolenghi, S, Robson, P, Creyghton, M, Bovolenta, P, Pavesi, G, Guillemot, F, Nicolis, S, Wei, C, and Hubrecht Institute for Developmental Biology and Stem Cell Research

Subjects
Model organisms, SOX2, Gene Expression, Biology, Article, neural stem cell, 03 medical and health sciences, 0302 clinical medicine, Genetic, Genetics, chromatin connectivity, Epigenetics, Enhancer, Transcription factor, transcription factor, ChIA-PET, 030304 developmental biology, 0303 health sciences, FOS: Clinical medicine, Stem Cells, Neurosciences, Promoter, Cell Biology, Chromatin, Cell biology, embryonic structures, Molecular Medicine, biological phenomena, cell phenomena, and immunity, Genetics & Genomics, Chromatin immunoprecipitation, 030217 neurology & neurosurgery, Developmental Biology
Abstract

We recently investigated the prognostic impact of a Chronic Care Model (CCM)-based healthcare program applied in primary care in Tuscany Region mainly run by multidisciplinary teams composed of general practitioners (GPs) and nurses. The project included proactively planned follow-up visits for each patient, individualized counselling to optimize lifestyle modifications and adherence to appropriate diagnostic and therapeutic pathways. 1761 patients with Chronic heart failure (CHF) directly enrolled by the GPs were matched with 3522 CHF controls not involved in the project. Over a 4-year follow-up in the CCM group a higher CHF hospitalization rate was found (12.1 vs 10.3 events/100 patient-years; incidence rate ratio [IRR] 1.15, p=0.0030), whereas mortality was lower (10.8 vs 12.6 events/100 patient-years; IRR 0.82, p0.0001). The CCM status was independently associated with a 34% increase in the risk of CHF hospitalization and a 18% reduction in the risk of death (p0.0001 for both). The CCM status was associated with a 50% increase in the rate of planned Heart failure (HF) hospitalizations whereas the rate of 1-month CHF readmissions showed no differences. Such a divergent trend could be explained by the direct involvement of GPs in the CCM program, leading them to a better awareness of patients' clinical status, and then to a more frequent use of clinical pathways and facilities, including hospitalization. It is reasonable to argue that not all hospitalizations must necessarily be considered as a poor outcome, as they often provide additional opportunities to improve therapies, optimize patient education, or define follow-up strategies. The evidence of a divergent trend between mortality and hospitalization in our population might support the clinical importance of a multidisciplinary approach for the management of patients with HF.

Published
2019

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