67 results on '"Ghiso, Jorge"'
Search Results
2. Ion channel formation by N-terminally truncated Aβ (4–42): relevance for the pathogenesis of Alzheimer's disease
3. Aβ truncated species: Implications for brain clearance mechanisms and amyloid plaque deposition
4. Proteomic Analysis Shows Constitutive Secretion of MIF and p53-associated Activity of COX-2 −/− Lung Fibroblasts
5. Comparative pathobiology of β-amyloid and the unique susceptibility of humans to Alzheimer's disease
6. The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain
7. Oxidative stress and mitochondria-mediated cell death mechanisms triggered by the familial Danish dementia ADan amyloid
8. Sequential Amyloid-β Degradation by the Matrix Metalloproteases MMP-2 and MMP-9
9. Mitochondrial dysfunction induced by a post-translationally modified amyloid linked to a familial mutation in an alternative model of neurodegeneration
10. Abundant pyroglutamate-modified ABri and ADan peptides in extracellular and vascular amyloid deposits in familial British and Danish dementias
11. Major Carboxyl Terminal Fragments Generated by γ-Secretase Processing of the Alzheimer Amyloid Precursor Are 50 and 51 Amino Acids Long
12. Matrix Metalloproteinase 2 (MMP-2) Degrades Soluble Vasculotropic Amyloid-β E22Q and L34V Mutants, Delaying Their Toxicity for Human Brain Microvascular Endothelial Cells
13. Iowa Variant of Familial Alzheimer’s Disease
14. BRI2 homodimerizes with the involvement of intermolecular disulfide bonds
15. Dutch and arctic mutant peptides of β amyloid1–40 differentially affect the FGF-2 pathway in brain endothelium
16. Human chorionic gonadotropin (a luteinizing hormone homologue) decreases spatial memory and increases brain amyloid-β levels in female rats
17. Preferential association of serum amyloid P component with fibrillar deposits in familial British and Danish dementias: Similarities with Alzheimer's disease
18. Brain neprilysin activity and susceptibility to transgene-induced Alzheimer amyloidosis
19. Familial Danish Dementia
20. BRI2 Interacts with Amyloid Precursor Protein (APP) and Regulates Amyloid β (Aβ) Production
21. The Familial Dementia BRI2 Gene Binds the Alzheimer Gene Amyloid-β Precursor Protein and Inhibits Amyloid-β Production
22. Insulin-degrading enzyme degrades amyloid peptides associated with British and Danish familial dementia
23. Insulin-degrading Enzyme in Brain Microvessels
24. Systemic Catabolism of Alzheimer's Aβ40 and Aβ42
25. Cholesterol in neurologic disorders of the elderly: stroke and Alzheimer’s disease
26. Soluble Aβ homeostasis in AD and DS: impairment of anti-amyloidogenic protection by lipoproteins
27. O2-03-07 Biochemical analysis of Aβ amyloid deposits in the Iowa variant of Alzheimer's disease
28. P3-407 Sirna-mediated BRI2 gene silencing in human neuronal cells
29. P1-262 Familial British and Danish dementias: BRI2 gene and protein expression by human cerebral cells
30. P1-264 The possible origin of the amyloid peptides in the BRI2 gene-related dementias
31. S5-02-02 Molecular pathology of non-Aβ cerebral amyloidosis
32. P1-177 Insulin degrading enzyme from human brain microvessels degrades amyloid β and its flemish, Dutch and Italian vasculotropic variants
33. pH-Dependent Amyloid and Protofibril Formation by the ABri Peptide of Familial British Dementia
34. Differential Degradation of Amyloid β Genetic Variants Associated with Hereditary Dementia or Stroke by Insulin-degrading Enzyme
35. Complement Activation in Chromosome 13 Dementias
36. Amyloidosis and Alzheimer’s disease
37. Circulating amyloid-β peptide crosses the blood–brain barrier in aged monkeys and contributes to Alzheimer's disease lesions
38. Systemic Amyloid Deposits in Familial British Dementia
39. Amyloid and Nonfibrillar Deposits in Mice Transgenic for Wild-Type Human Transthyretin: A Possible Model for Senile Systemic Amyloidosis
40. Sequence, genomic structure and tissue expression of Human BRI 3 , a member of the BRI gene family
41. Regional Distribution of Amyloid-Bri Deposition and Its Association with Neurofibrillary Degeneration in Familial British Dementia
42. Carboxyl-terminal Fragments of Alzheimer β-Amyloid Precursor Protein Accumulate in Restricted and Unpredicted Intracellular Compartments in Presenilin 1-deficient Cells
43. Substitutions at Codon 22 of Alzheimer's Aβ Peptide Induce Diverse Conformational Changes and Apoptotic Effects in Human Cerebral Endothelial Cells
44. N-terminal pyroglutamate enhances the fibrillogenic properties of the ABRI peptide in familial British dementia
45. BRI amyloid precursor protein isoforms. BRI2 is mutated in familial British dementia
46. Cerebral deposition of ABRI amyloid in familial British dementia
47. A decamer duplication in the BRI gene originates a de-novo amyloid peptide that causes dementia in a Danish kindred
48. A new syndrome of dementia
49. Somatic Mutations of the L12a Gene in V-κ1 Light Chain Deposition Disease
50. Potent Neuroprotective Properties against the Alzheimer β-Amyloid by an Endogenous Melatonin-related Indole Structure, Indole-3-propionic Acid
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