1. The association between physical activity time and neuropathy in longstanding type 1 diabetes: A cross-sectional analysis of the Canadian study of longevity in type 1 diabetes
- Author
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Evan J H, Lewis, Leif E, Lovblom, Sebastien, Lanctot, Daniel, Scarr, Nancy, Cardinez, Genevieve, Boulet, Alanna, Weisman, Julie A, Lovshin, Yuliya, Lytvyn, Hillary A, Keenan, Michael H, Brent, Narinder, Paul, David Z I, Cherney, Vera, Bril, and Bruce A, Perkins
- Subjects
Canada ,Cross-Sectional Studies ,Diabetes Mellitus, Type 1 ,Endocrinology ,Diabetic Neuropathies ,Endocrinology, Diabetes and Metabolism ,Longevity ,Internal Medicine ,Humans ,Middle Aged ,Exercise ,Aged - Abstract
Physical activity (PA) is recommended to improve glycemic control in T1D; however, the effect of PA on distal symmetric polyneuropathy (DSPN) and cardiac autonomic function in longstanding T1D is unknown.Data from 75 participants were collected as part of the Canadian Study of Longevity in T1D. Participants completed a physical exam, medical history, extensive complications phenotyping and reported their daily PA from the preceding 12-months. Pearson and Spearman correlations were used to assess PA time and complications variables. Linear regression was used to test associations between PA time, neurological and electrophysiological measures. Univariable regression was used to indicate the change in the given independent variables associated with a 30-min increase in PA per week.Participants were 66 ± 8 years old with diabetes duration of 54 [52,58] years, HbAIn longstanding T1D, PA time is associated with superior large nerve fibre function in the lower limbs and some better measures of small nerve fibre function.
- Published
- 2022