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1. Onchocerca volvulus: identification of cDNAs encoding a putative phosphatidyl-ethanolamine-binding protein and a putative partially processed mRNA precursor

Author

Klaus D. Erttmann and Gallin My

Subjects
DNA, Complementary, Transcription, Genetic, Odorant binding, Molecular Sequence Data, Sequence alignment, Open Reading Frames, Transcription (biology), Complementary DNA, parasitic diseases, Genetics, Animals, Amino Acid Sequence, RNA, Messenger, Cloning, Molecular, skin and connective tissue diseases, Peptide sequence, Gene, Genes, Helminth, Base Sequence, integumentary system, biology, Phosphatidylethanolamines, Chromosome Mapping, Helminth Proteins, General Medicine, biology.organism_classification, Onchocerca volvulus, Molecular biology, Carrier Proteins, Precursor mRNA, Sequence Alignment
Abstract

We have identified and sequenced cDNAs of the parasitic nematode Onchocerca volvulus which encode a homologue of phosphatidylethanolamine-binding proteins from mammals. These clones are also closely related to the O. volvulus Ov16 cDNA (Lobos et al., 1990). One identified cDNA clone appears to represent a partially processed precursor. These results suggest that these cDNAs are derived from a complex genomic locus, raising the possibility of polycistronic transcription in this nematode.

Published
1996

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