90 results on '"Gallagher, J.A."'
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2. Temporal adaptations in the phenylalanine/tyrosine pathway and related factors during nitisinone-induced tyrosinaemia in alkaptonuria
3. Characterization of changes in the tyrosine pathway by 24-h profiling during nitisinone treatment in alkaptonuria
4. Treatment of osteoporotic fractures in alkaptonuria by teriparatide stimulates bone formation and decreases fracture rate – A report of two cases
5. What Rare Diseases Can Tell Us About OA
6. A comparison between high density mineralised protrusions identified in the knees of cadavers and in patients of the osteoarthritis initiative
7. Interference of hydroxyphenylpyruvic acid, hydroxyphenyllactic acid and tyrosine on routine serum and urine clinical chemistry assays; implications for biochemical monitoring of patients with alkaptonuria treated with nitisinone
8. Raman Spectroscopy identifies differences in ochronotic and non-ochronotic cartilage; a potential novel technique for monitoring ochronosis
9. Extracellular chemical profiling by LC-QTOF-MS identifies novel bone resorption markers for monitoring progression of osteoarthropathy in the rare disease alkaptonuria
10. Osteoarthritic subchondral bone marrow histology. Lessons from changes in alkaptonuria
11. Data on items of AKUSSI in Alkaptonuria collected over three years from the United Kingdom National Alkaptonuria Centre and the impact of nitisinone
12. Nitisinone arrests ochronosis and decreases rate of progression of Alkaptonuria: Evaluation of the effect of nitisinone in the United Kingdom National Alkaptonuria Centre
13. Clinical and biochemical assessment of depressive symptoms in patients with Alkaptonuria before and after two years of treatment with nitisinone
14. Inflammatory and oxidative stress biomarkers in alkaptonuria: data from the DevelopAKUre project
15. Raman spectroscopy can non-invasively distinguish between ochronotic and non-ochronotic cartilage
16. Disruption of collagen triple helix hydrogen bonding in ochronotic human cartilage in alkaptonuria observed by dynamic nuclear polarisation-enhanced solid-state nuclear magnetic resonance spectroscopy
17. Combined LC-QTOF-MS urine metabolomics and 18F-NaF PET imaging indicates novel compounds associated with spine osteoarthropathy in the rare disease alkaptonuria
18. Generation and phenotyping of a targeted mouse model of alkaptonuria
19. Laser ablation machined sections permit correlative studies of hdmps by X-ray microtomography, optical and scanning electron microscopy
20. Longitudinal survey for high density mineralised protrusions identified by 3D dess MRI in patients of the osteoarthritis initiative
21. An Investigation of High Density Mineralised Protrusions in Human Cadaveric Knees by MRI and Microtomography
22. Anatomical distribution of 18F PET signal in patients with osteoarthropathy of alkaptonuria
23. Identification of high density mineralised protrusions in human knees ex-vivo and in-situ by clinical scanning techniques
24. High density mineralised protrusions from the tidemark into hyaline cartilage in human joints
25. Analysis of cartilage biomarkers of aging and turnover in the osteoarthropathy of alkaptonuria
26. Urine homogentisic acid and tyrosine: Simultaneous analysis by liquid chromatography tandem mass spectrometry
27. Identification of concentric lamellae in the articular calcified cartilage of osteoarthritic mice
28. Rare syndromes: what they teach us about osteoarthritis disease mechanisms
29. Initiation and progression of ochronotic osteoarthropathy in alkaptonuric mice
30. Identification of subchondral protrusions by magnetic resonance imaging: a novel biomarker of joint degeneration
31. ATP-Stimulated ATP release and metabolic acid production:-regulating life and death decisions in articular chondrocytes
32. Ochronosis in a murine model of alkaptonuria is synonymous to that in the human condition
33. Seasonal variation in Laminaria digitata and its impact on biochemical conversion routes to biofuels
34. 159 ANALYSIS OF CARTILAGE BIOMARKERS OF TURNOVER AND AGING IN THE OSTEOARTHROPATHY OF ALKAPTONURIA
35. Advanced ochronosis of articular cartilage in aku provides an extreme model of focal unloading of bone due to stress shielding
36. Adiponectin receptors in multinucleated osteoclast-like cells
37. Seasonal variation in the chemical composition of the bioenergy feedstock Laminaria digitata for thermochemical conversion
38. 257 ELUCIDATING THE MECHANISM OF OSTEOARTHROPATHY IN ALKAPTONURIA: LESSONS FOR OSTEOARTHRITIS
39. 106 IDENTIFICATION OF JOINT OCHRONOSIS IN A MOUSE MODEL OF ALKAPTONURIA
40. Lipopolysaccharide (LPS) alters expression of incretin receptors in monocytic and hepatocytic cell lines
41. Type VI collagen plays a major role in adhesion of osteoblastic cells
42. Time course and mechanisms of the synergistic activation of osteoblastic cells by extracelluar ATP and PTH
43. Deposition of ochronotic pigment in articular cartilage in alkaptonuria is initiated near the tidemark and progresses to the articular surface
44. 457 ULTRASTRUCTURAL ANALYSIS OF COLLAGEN IN THE ARTHROPATHY OF ALKAPTONURIA IN VIVO AND IN VITRO
45. Effects of adiponectin on the osteoblastic-like cell line Saos-2
46. Collagen VI is present in bone and its expression is inversely correlated with maturity
47. Enhanced growth and matrix production by human osteoblastic cells cultured on biomaterials with negative zeta potential
48. Potassium channel activator bl-1249 inhibits the c-fos response to parathyroid hormone in osteoblastic cells in a dose-dependent manner
49. Extracellular ATP, signalling through P2 receptors, synergises with glucose-dependent insulinotropic polypeptide to induce c-fos in osteoblastic cells
50. Gut hormones receptors and their effects on osteoblastic-like cell lines
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