55 results on '"Fromenty, Bernard"'
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2. Low concentrations of ethylene bisdithiocarbamate pesticides maneb and mancozeb impair manganese and zinc homeostasis to induce oxidative stress and caspase-dependent apoptosis in human hepatocytes
3. NAFLD et dysfonction mitochondriale
4. Mitochondrial alterations in fatty liver diseases
5. Advanced preclinical models for evaluation of drug-induced liver injury – consensus statement by the European Drug-Induced Liver Injury Network [PRO-EURO-DILI-NET]
6. Advanced preclinical models for evaluation of drug-induced liver injury – consensus statement by the European Drug-Induced Liver Injury Network [PRO-EURO-DILI-NET]
7. Multikinase inhibitor-induced liver injury in patients with cancer: A review for clinicians
8. Cytochrome P450 2E1 should not be neglected for acetaminophen-induced liver injury in metabolic diseases with altered insulin levels or glucose homeostasis
9. Treatments in Covid-19 patients with pre-existing metabolic dysfunction-associated fatty liver disease: A potential threat for drug-induced liver injury?
10. Non-oxidative ethanol metabolism in human hepatic cells in vitro: Involvement of uridine diphospho-glucuronosyltransferase 1A9 in ethylglucuronide production
11. Fatal acetaminophen poisoning with hepatic microvesicular steatosis in a child after repeated administration of therapeutic doses
12. Rôle des acides gras dans l’induction du cytochrome P450 2E1 hépatique : implication dans la stéatohépatite non-alcoolique (NASH) liée à l’obésité
13. Alteration of mitochondrial DNA homeostasis in drug-induced liver injury
14. Inhibition of mitochondrial fatty acid oxidation in drug-induced hepatic steatosis
15. Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol: a possible key role for xenobiotic metabolism and nitric oxide
16. A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: Application to acetaminophen
17. A cellular model to study acetaminophen-induced hepatotoxicity in the context of nonalcoholic fatty liver disease
18. Mitochondrial dysfunctions in liver due to environmental drug contaminants and obesity
19. Aggravation des hépatopathies liées à l’obésité par les xénobiotiques
20. Chronic exposure to low doses of pharmaceuticals disturbs the hepatic expression of circadian genes in lean and obese mice
21. Prediction of drug-induced liver injury in human with a multiparametric assay on the HepaRG® cell line
22. Administration of very low doses of water pharmaceutical contaminants in lean and obese mice disturbs the hepatic expression of genes involved in circadian rhythm
23. Drug-induced liver injury in obesity
24. Low doses of water pharmaceutical contaminants disturb hepatic gene expression in mice
25. Carbon tetrachloride-mediated lipid peroxidation induces early mitochondrial alterations in mouse liver
26. Drug-induced toxicity on mitochondria and lipid metabolism: Mechanistic diversity and deleterious consequences for the liver
27. Mitochondrial CYP2E1 is sufficient to mediate oxidative stress and cytotoxicity induced by ethanol and acetaminophen
28. Overexpression of Bcl-2 in hepatocytes protects against injury but does not attenuate fibrosis in a mouse model of chronic cholestatic liver disease
29. Evaluation of drug toxicity using isolated mouse liver mitochondria
30. Protection against Hepatocyte Mitochondrial Dysfunction Delays Fibrosis Progression in Mice
31. Prolonged ethanol administration depletes mitochondrial DNA in MnSOD-overexpressing transgenic mice, but not in their wild type littermates
32. Mitochondrial dysfunction in nonalcoholic steatohepatitis (NASH): are there drugs able to improve it?
33. High concentrations of stavudine impair fatty acid oxidation without depleting mitochondrial DNA in cultured rat hepatocytes
34. High hepatic glutathione stores alleviate Fas-induced apoptosis in mice
35. Mitochondrial dysfunction in NASH: Causes, consequences and possible means to prevent it
36. NASH: a mitochondrial disease
37. Mitochondria are sensors for HIV drugs
38. Impaired adaptive resynthesis and prolonged depletion of hepatic mitochondrial DNA after repeated alcohol binges in mice
39. Homozygosity for alanine in the mitochondrial targeting sequence of superoxide dismutase and risk for severe alcoholic liver disease
40. An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice
41. Steatohepatitis-inducing drugs cause mitochondrial dysfunction and lipid peroxidation in rat hepatocytes
42. Multiple hepatic mitochondrial DNA deletions suggest premature oxidative aging in alcoholic patients
43. Impaired mitochondrial function in microvesicular steatosis effects of drugs, ethanol, hormones and cytokines
44. Microvesicular steatosis and steatohepatitis: role of mitochondrial dysfunction and lipid peroxidation
45. Assessment of the prevalence of genetic metabolic defects in acute fatty liver of pregnancy
46. Efficient and specific amplification of identified partial duplications of human mitochondrial DNA by long PCR
47. Acute and chronic hepatic steatosis lead to in vivo lipid peroxidation in mice
48. Hepatic mitochondrial DNA deletion in alcoholics: Association with microvesicular steatosis
49. Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity
50. Possible role of HLA in hepatotoxicity
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