104 results on '"Fang, Cui"'
Search Results
2. Built-in electric field boosted ionic transport kinetics in the heterostructured ZnCo2O4/ZnO nanobelts for high-performance supercapacitor
- Author
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Qinghai Ma, Fang Cui, Jiajia Zhang, and Tieyu Cui
- Subjects
Biomaterials ,Colloid and Surface Chemistry ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials - Published
- 2023
3. Proactive and reactive cognitive control for emotional conflict in individuals with high schizotypy: An ERP study
- Author
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Lu-xia Jia, Jun-yan Ye, Ji-fang Cui, Hai-song Shi, Tian-xiao Yang, and Ya Wang
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Neurology ,Physiology (medical) ,Neurology (clinical) ,Sensory Systems - Abstract
The present study aimed to examine how individuals with high schizotypy, a high risk group of schizophrenia patients, resolve emotional conflict in proactive and reactive control and the underlying neural mechanisms.Thirty-two individuals with high schizotypy and 30 matched individuals with low schizotypy completed an emotional face-word Stroop task with electroencephalographic data recorded. The proportion of incongruent trials was manipulated in the task to induce proactive control (mostly incongruent trials context, MI context) or reactive control (mostly congruent trials context, MC context). Two event-related potential (ERP) components (N170 and N2) were examined, which represent face processing and cognitive control processes, respectively.In the MC context, significantly decreased N2 and N170 amplitudes were found in high schizotypy individuals compared with low schizotypy individuals, suggesting abnormal neural activity of reactive control in high schizotypy individuals. No significant differences were found between the two groups in the MI context.These results provide initial evidence for dissociation of neural activity of proactive and reactive control on emotional conflict in individuals with high schizotypy.The current findings provide important insight into the emotional conflict resolution in the schizophrenia spectrum.
- Published
- 2023
4. Chronic Intermittent Hypobaric Hypoxia Improves Iron Metabolism Disorders Via the IL-6/JAK2/STAT3 and Epo/STAT5/ERFE Signaling Pathways in Metabolic Syndrome Rats
- Author
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Fang Cui, Jie Sun, Haichao Mi, Bo Li, Longmei Tang, Ruotong Wang, Yutao Du, and Min Shi
- Published
- 2023
5. Investigation Tribological Behavior of Plasma Sprayed Ni-Based Coating Prepared on Aluminum Alloy Under Different Temperatures
- Author
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Bing-yuan Han, Xiang-han Gao, Shu-ying Chen, Meng-qi Cong, Fang-fang Cui, Wei-xing Hang, Hai-dong Wu, and Jia-jie Chu
- Abstract
Ni-based alloy is a typical high-temperature alloy material possessing high hardness, good thermal stability, and wear resistance. It is widely used as the surface strengthening and repair materials for aviation, vehicle engines, and industrial parts. In this study, Ni60 alloy coating was prepared on the surface of ZL109 aluminum alloy by plasma spraying technology, and its tribological properties at different temperatures (T = 25 ℃, 100 ℃ and 350 ℃) were evaluated. X-ray diffraction (XRD) and Scanning Electron Microscopy (SEM) with Energy Dispersive X-ray Spectroscopy (EDS) were used to characterize the phase analysis, micromorphology of Ni60 alloy coating fabricated with different spraying distance(D = 100 mm, 110 mm and 120 mm). The result shows that with the increase of spraying distance, the defects such as pores and microcracks decrease gradually. The porosity decreased from 2.2–0.76% and the fractal dimension decreased from 1.83 to 1.57. The element composition (Ni, Fe, Cr, Si, C, B) and phase composition (Ni3Fe, Cr23C6 and Cr7C3) of powder and coating were basically the same. The microhardness of the coating after spraying was about 5 times higher than that of the substrate. When D = 120 mm, the microhardness and bonding strength of the coating were the highest, which were 804 HV0.1 and 26 ± 0.05 MPa, respectively. The friction coefficient of the coating in the stable stage decreased with the increase of temperature, and all change in the range of 0.1 ~ 0.2. With the increase of temperature, the width, depth and volume wear rate of the coating increase gradually.
- Published
- 2023
6. Response of carbohydrate metabolism-mediated sink strength to auxin in shoot tips of apple plants
- Author
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Jing SU, Wei-fang CUI, Ling-cheng ZHU, Bai-yun LI, Feng-wang MA, and Ming-jun LI
- Subjects
Ecology ,sink strength ,Agriculture (General) ,fungi ,food and beverages ,apple ,shoot tips ,Plant Science ,Biochemistry ,S1-972 ,exogenous IAA ,Food Animals ,carbohydrate metabolism ,Animal Science and Zoology ,Agronomy and Crop Science ,Food Science - Abstract
Auxin (indole-3-acetic acid, IAA) has a considerable impact on the regulation of plant carbohydrate levels and growth, but the mechanism by which it regulates sugar levels in plants has received little attention. In this study, we found that exogenous IAA altered fructose (Fru), glucose (Glc), and sucrose (Suc) concentrations in shoot tips mainly by regulating MdSUSY1, MdFRK2, MdHxK1 and MdSDH2 transcript levels. Additionally, we used 5-year-old ‘Royal Gala’ apple trees to further verify that these genes play primary roles in regulating sink strength. The results showed that MdSUSY1, MdFRK2, MdHxK1/3 and MdSDH2 might be major contributors to sink strength regulation. Taken together, these results provide new insight into the regulation of the carbohydrate metabolism mechanism, which will be helpful for regulating sink strength and yield.
- Published
- 2022
7. Neural correlates of mental time travel in individuals with high level of schizotypy
- Author
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Jun-yan Ye, Xiao-jing Qin, Ji-Fang Cui, Hai-song Shi, Jia-Li Liu, Jia Huang, Yi Wang, Tian-Xiao Yang, Simon S.Y. Lui, Ya Wang, and Raymond C.K. Chan
- Subjects
Pharmacology ,Biological Psychiatry - Published
- 2023
8. Emerging optically active tetraphenylenes: Advances and challenges in synthesis and applications in asymmetric catalysis and chiral functional materials
- Author
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Hao-Ran Ma, Xiao-Shui Peng, Jian-Fang Cui, and Henry Nai Ching Wong
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Organic Chemistry ,Drug Discovery ,Biochemistry - Published
- 2023
9. Fresh look at experimental evidence for odderon exchange
- Author
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Zhu-Fang Cui, Daniele Binosi, Craig D. Roberts, Sebastian M. Schmidt, and D.N. Triantafyllopoulos
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Nuclear Theory (nucl-th) ,High Energy Physics - Phenomenology ,High Energy Physics - Experiment (hep-ex) ,Nuclear and High Energy Physics ,High Energy Physics - Lattice ,High Energy Physics - Phenomenology (hep-ph) ,Nuclear Theory ,High Energy Physics - Lattice (hep-lat) ,FOS: Physical sciences ,Nuclear Experiment (nucl-ex) ,Nuclear Experiment ,High Energy Physics - Experiment - Abstract
Theory suggests that in high-energy elastic hadron+hadron scattering, $t$-channel exchange of a family of colourless crossing-odd states -- the odderon -- may generate differences between $p\bar p$ and $pp$ cross-sections in the neighbourhood of the diffractive minimum. Using a mathematical approach based on interpolation via continued fractions enhanced by statistical sampling, we develop robust comparisons between $p\bar p$ elastic differential cross-sections measured at $\surd s=1.96\,$TeV by the D0 Collaboration at the Tevatron and function-form-unbiased extrapolations to this energy of kindred $pp$ measurements at $\surd s /{\rm TeV} = 2.76, 7, 8, 13$ by the TOTEM Collaboration at the LHC and a combination of these data with earlier cross-section measurements at $\surd s/{\rm GeV} = 23.5, 30.7, 44.7, 52.8, 62.5$ made at the internal storage rings. Focusing on a domain that straddles the diffractive minimum in the $p\bar p$ and $pp$ cross-sections, we find that these two cross-sections differ at the $(2.2-2.6)\sigma$ level; hence, supply evidence with this level of significance for the existence of the odderon. If combined with evidence obtained through different experiment-theory comparisons, whose significance is reported to lie in the range $(3.4-4.6)\sigma$, one arrives at a $(4.0 - 5.2)\sigma$ signal for the odderon., Comment: 8 pages, 5 figures
- Published
- 2023
10. Neural correlates of schizotypal traits: Findings from connectome-based predictive modelling
- Author
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Tao Chen, Jia Huang, Ji-fang Cui, Zhi Li, Muireann Irish, Ya Wang, and Raymond C.K. Chan
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Psychiatry and Mental health ,General Medicine ,General Psychology - Abstract
Schizotypal traits can be conceptualized as a phenotype for schizophrenia spectrum disorders. As such, a better understanding of schizotypal traits could potentially improve early identification and treatment of schizophrenia. We used connectome-based predictive modelling (CPM) based on whole-brain resting-state functional connectivity to predict schizotypal traits in 82 healthy participants. Results showed that only the negative network could reliably predict an individual's schizotypal traits (r = 0.29). The 10 nodes with the highest edges in the negative network were those known to play a key role in sensation and perception, cognitive control as well as motor control. Our findings suggest that CPM might be a promising approach to improve early identification and prevention of schizophrenia from a spectrum perspective.
- Published
- 2023
11. Balanced time perspective and its relationship with clinical and cognitive symptoms in schizophrenia
- Author
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Tao Chen, Xiao-jing Qin, Ji-fang Cui, Ming-yuan Gan, Shu-ping Tan, Ya Wang, and Muireann Irish
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General Psychology - Published
- 2023
12. Proactive and reactive response inhibition of individuals with high schizotypy viewing different facial expressions: An ERP study using an emotional stop-signal task
- Author
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Lu-Xia, Jia, Qi, Zheng, Ji-Fang, Cui, Hai-Song, Shi, Jun-Yan, Ye, Tian-Xiao, Yang, Ya, Wang, and Raymond C K, Chan
- Subjects
General Neuroscience ,Neurology (clinical) ,Molecular Biology ,Developmental Biology - Abstract
The present study aimed to examine whether impairments in reactive (outright stopping) and proactive (preparation for stopping) response inhibition are affected by negative emotions in individuals with high schizotypy, a subclinical group at risk for schizophrenia, as well as the neural mechanisms underlying these processes. Twenty-seven participants with high schizotypy and 28 matched low-schizotypy individuals completed an emotional stop-signal task in which they responded to facial emotions (neutral or angry) or inhibited their responses (when the frame of the picture turned red). Electroencephalogram (EEG) data were also recorded during the task. At the neural level, analysis of go trials revealed that viewing angry faces impaired proactive inhibition. In addition, the high-schizotypy group exhibited a greater P3 amplitude in go trials in the neutral condition than the low-schizotypy group; however, no group difference was found in the angry condition. For stop trials (reactive inhibition), a smaller P3 amplitude was found in the angry condition than in the neutral condition. Moreover, high-schizotypy individuals showed smaller P3 amplitudes than low-schizotypy individuals. The current findings suggest that, at the neural level, viewing negative emotions impaired both proactive and reactive response inhibition. Individuals with high schizotypy exhibited impairments in proactive response inhibition in the neutral condition but not in the angry condition; they exhibited impaired reactive response inhibition in both emotion conditions. The present findings deepen our understanding of emotional response inhibition in individuals on the schizophrenia spectrum.
- Published
- 2023
13. Construction of magnetic NiO/C nanosheets derived from coordination polymers for extraordinary adsorption of dyes
- Author
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Jiajia Zhang, Fang Cui, Qinghai Ma, Yiwen Gao, Yang Liu, Tieyu Cui, and Linxu Xu
- Subjects
chemistry.chemical_classification ,Materials science ,Graphene ,Non-blocking I/O ,chemistry.chemical_element ,02 engineering and technology ,Polymer ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,law.invention ,Biomaterials ,Colloid and Surface Chemistry ,Adsorption ,chemistry ,Chemical engineering ,law ,Specific surface area ,Self-assembly ,0210 nano-technology ,Carbon ,Nanosheet - Abstract
Herein, a facial stratagem for the large-scale synthesis of NiO/C nanosheets used as magnetic adsorbents is proposed by using nanoscale coordination polymers (nanoCPs) as precursors. The NiO nanoparticles (NPs) scattered on the NiO/C nanosheets have an untrasmall size (~3 nm) as well as uniform dispersion, since the Ni2+ ions are preassembled into the nanoCPs precursors by coordination bonds and transformed to NiO NPs in situ under the restriction of carbon layers. Thanks to the small size and spatially uniform distribution of NiO NPs, fully exposed carbon matrix containing part of graphene structures, and the high specific surface area of the special nanosheet structure, the magnetic NiO/C nanosheets have an a great breakthrough in the adsorption performance toward Congo Red (CR) among many reported NiO-based materials. The maximum adsorption capacity for CR is up to 2000 mg/g, and the adsorption kinetics and thermodynamics are also systematically studied. Moreover, the NiO/C nanosheets can be separated from water and reused simply by an external magnetic field. The NiO/C nanosheets with low cost and extraordinary adsorption ability have great potential in water pollution treatment area.
- Published
- 2020
14. The effect of implementation intentions on prospective memory performance in patients with schizophrenia: A multinomial modeling approach
- Author
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Ying Li, Lu-lu Liu, Tian-xiao Yang, David Shum, Raymond C.K. Chan, Ji-fang Cui, David L. Neumann, Ya Wang, and Tao Chen
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Adult ,Male ,medicine.medical_specialty ,Memory, Episodic ,Intention ,Audiology ,03 medical and health sciences ,0302 clinical medicine ,Prospective memory ,Humans ,Medicine ,Cognitive Dysfunction ,In patient ,Biological Psychiatry ,Memory Disorders ,Models, Statistical ,business.industry ,Middle Aged ,medicine.disease ,030227 psychiatry ,Psychiatry and Mental health ,Schizophrenia ,Mental Recall ,Female ,business ,Goals ,Psychomotor Performance ,030217 neurology & neurosurgery - Abstract
Patients with schizophrenia (SCZ) consistently show prospective memory (PM) impairments, and the technique of implementation intentions has been shown to improve PM performance in these patients. PM is considered to have prospective and retrospective components. However, it remains unclear which component of PM is impaired in patients with SCZ and which component(s) is facilitated by implementation intentions (II). The present study aimed to examine these two issues. Forty-two patients with SCZ and 42 matched healthy controls were randomly assigned to an II group or a typical instruction group. All participants were administered a color-matching PM task. Results showed that, using a multinomial-modeling approach, patients with SCZ exhibited impairment in the retrospective component of PM. In addition, while II improved the prospective PM component in healthy controls, both prospective and retrospective PM components in patients with SCZ were improved. Together, our results shed light on the mechanism of PM impairment in SCZ patients and the mechanism of II in improving PM performance.
- Published
- 2020
15. Molecular cloning, expression and biological activity of rhesus macaque interleukin-17A and interleukin-17F
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Gui-Bo Yang, Yan-Fang Cui, Xiu-Li Shen, Feng-Jie Wang, and Lei Yu
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THP-1 Cells ,Immunology ,Inflammation ,Molecular cloning ,Cell Line ,Proinflammatory cytokine ,Exon ,medicine ,Animals ,Humans ,Cloning, Molecular ,Molecular Biology ,Gene ,Peptide sequence ,biology ,Tumor Necrosis Factor-alpha ,Interleukin-17 ,NF-kappa B ,biology.organism_classification ,Macaca mulatta ,Molecular biology ,Rhesus macaque ,Cytokines ,Interleukin 17 ,Caco-2 Cells ,medicine.symptom - Abstract
Interleukin-17A (IL-17A) and interleukin-17F (IL-17F) as two potent proinflammatory cytokines and the signature cytokines of Th17 cells play important roles in human autoimmune diseases, inflammation and host defenses. In this study, rhesus macaque IL-17A (rhIL-17A) and IL-17F (rhIL-17F) were cloned and expressed, and their biological activities and in vivo distribution were examined. The resulting data showed that both the rhIL-17A and rhIL-17F genes were consisted of three exons and two introns. RhIL-17A and rhIL-17F shared 96.8% and 93.9% amino acid sequence identity with human IL-17A (huIL-17A) and IL-17F (huIL-17F) respectively and the sequences also shared one N-glycosylation site and six conserved cysteine residues with huIL-17A and huIL-17F. IL-17A and IL-17F transcripts were highly expressed in lymphoid tissues and the intestinal tract of rhesus macaques. Functionally, recombinant rhIL-17A and rhIL-17F showed similar effect on Act1 levels and NF-κB phosphorylation compared with that of commercial human IL-17A and IL-17F. Moreover, the antibacterial proteins (such as β-defensin 2, S100A8, S100A9, RegIIIα and Muc1) and the tight junction associated genes (including CLDN1, CLDN4, OCLN, and ZO1) expressed by Caco-2 cells were largely enhanced after treatment with rhIL-17A and rhIL-17F. Meanwhile, purified rhIL-17A and rhIL-17F could also induce the expression of IL-6 and TNF-α by THP-1 cells. These data indicated that rhesus macaque IL-17A and IL-17F are highly similar to that of humans in both structure and function. Studies on rhIL-17A/rhIL-17F are promising approach to contribute to the understanding of human IL-17A and IL-17F-related intestinal diseases.
- Published
- 2019
16. Synergized Ni/NiOx heterojunction encapsulated by N-doped graphitized carbon core@shell electrocatalyst for efficient hydrogen production
- Author
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Mengxue Liu, Jiajia Zhang, Fang Cui, Yuqi Yan, and Tieyu Cui
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Mechanics of Materials ,Mechanical Engineering ,General Materials Science ,Condensed Matter Physics - Published
- 2022
17. Microstructure and tribological behavior of plasma spray Ni60 alloy coating deposited on ZL109 aluminum alloy substrate
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Bing-yuan Han, Xiang-han Gao, Shu-ying Chen, Meng-qi Cong, Ren-xing Li, Xiao Liu, Wei-xing Hang, and Fang-fang Cui
- Subjects
Mechanics of Materials ,Mechanical Engineering ,Surfaces and Interfaces ,Surfaces, Coatings and Films - Published
- 2022
18. Facile construction of hexagonal Co3O4 as the electrode for high-performance supercapacitor
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Fangze Wu, Fang Cui, Qinghai Ma, Jiajia Zhang, Xin Qi, and Tieyu Cui
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Mechanics of Materials ,Mechanical Engineering ,General Materials Science ,Condensed Matter Physics - Published
- 2022
19. The different relationship pattern between mind wandering and daily prospective memory failure in individuals with high and low schizotypal traits
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Tao, Chen, Jing, Liu, Ji-Fang, Cui, Chun-Liu, Yang, Xiao-Jing, Qin, Hua, Xu, Ya, Wang, and Muireann, Irish
- Subjects
Psychiatry and Mental health ,Memory, Short-Term ,Memory, Episodic ,Humans ,Attention ,General Medicine ,General Psychology - Published
- 2022
20. Carbon onions coated Ni/NiO nanoparticles as catalysts for alkaline hydrogen evolution reaction
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Yuqi Yan, Qinghai Ma, Fang Cui, Jiajia Zhang, and Tieyu Cui
- Subjects
General Chemical Engineering ,Electrochemistry - Published
- 2022
21. Distinct aggregate stratification of antibiotic resistome in farmland soil with long-term manure application
- Author
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Jian-Hua, Cheng, Xiang-Yu, Tang, and Jun-Fang, Cui
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Manure ,Soil ,Farms ,Environmental Engineering ,Genes, Bacterial ,Humans ,Environmental Chemistry ,Pollution ,Waste Management and Disposal ,Soil Microbiology ,Anti-Bacterial Agents - Abstract
Agricultural soils, which are closely linked to human health via food supply, have been recognized as an important reservoir for antibiotic resistance genes (ARGs). However, there is still a lack of knowledge regarding the role of soil aggregates in shaping ARG profile. In this study, we collected soils from long-term experimental farmland plots receiving inorganic and/or organic fertilizers and examined the patterns of antibiotic resistome distribution among differently sized soil aggregates using high-throughput quantitative polymerase chain reaction (HT-qPCR). Our results showed that the distribution of soil ARGs could be affected by manure application and aggregate size individually but not interactively. More diverse and abundant ARGs were found in the manured soils, compared to the non-manured soils. The aggregate size fraction of53 μm exhibited the highest diversity and abundance of ARGs. Variation partitioning analysis revealed that soil traits, mobile genetic elements, and bacterial community collectively contributed to the variation of soil antibiotic resistance. The knowledge about aggregation stratification of soil ARGs obtained in this study is fundamental and essential to understanding the fate of soil ARGs at the microscale.
- Published
- 2022
22. The Role of MRI in Diagnosing and Managing Tracheal Diverticulum
- Author
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Zhang, Yuan, primary, Tan, Yiqing, additional, Chen, Jing, additional, and Fang, Cui, additional
- Published
- 2021
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23. The stereotype of professional roles influences neural responses to moral transgressions: ERP evidence
- Author
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Juanzhi Lu, Fang Cui, Xiaozhe Peng, and Chong Liao
- Subjects
Adult ,Male ,Subjective rating ,media_common.quotation_subject ,education ,Stereotype ,Morals ,050105 experimental psychology ,Judgment ,Young Adult ,03 medical and health sciences ,Professional Role ,0302 clinical medicine ,Humans ,0501 psychology and cognitive sciences ,Evoked Potentials ,health care economics and organizations ,media_common ,Stereotyping ,General Neuroscience ,05 social sciences ,humanities ,Neuropsychology and Physiological Psychology ,Female ,Psychology ,Social psychology ,030217 neurology & neurosurgery - Abstract
The person-centered account of moral judgments is important since immoral behaviors are diagnostic of an individual’s character. The present study explored how the professional stereotypes associated with the agents shaped the way people perceiving moral/immoral behaviors. The behavioral ratings and neural responses (i.e., P200, N2, LPC event-related potentials (ERPs)) to moral/immoral behaviors done by agents with respectable or ordinary professional roles were recorded and compared. Behaviorally, we found that participants rated the agent with a respectable professional role behaving immorally as more dislikable comparing to the agent with an ordinary professional role. For ERPs, we found that: 1) the agents with respectable professional roles elicited larger P200 than agents with ordinary professional roles did; 2) immoral behavior elicited larger LPC than moral behaviors did; 3) for agents with respectable professional roles, the immoral behaviors elicited significantly more positive N2 than the moral behaviors did whereas this difference was not significant for the agents with ordinary professional roles. The immoral behaviors done by agents with respectable professional roles elicited more positive N2 than the immoral behavior done by agents with ordinary professional roles. Moreover, this effect was correlated with the participants’ subjective rating of the professional roles’ respectable level. These results suggest that 1) the more the agents with respectable professional roles are respected, the more dislikable they became when behaving immorally; 2) the moral stereotype associated with professional roles can influence the early processing stage reflected in N2 but not the later evaluative process reflected in LPC.
- Published
- 2019
24. Investigation of the photoionization process of helium ion in bichromatic circularly XUV fields with different time delays
- Author
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Jie Shao, Jun-Lin Ma, Cai-Ping Zhang, Xiangyang Miao, Jing-Chao Jia, and Hui-Fang Cui
- Subjects
Physics ,Photon ,General Physics and Astronomy ,chemistry.chemical_element ,02 engineering and technology ,Photoionization ,Electron ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Laser ,01 natural sciences ,0104 chemical sciences ,Ion ,law.invention ,Momentum ,chemistry ,law ,Extreme ultraviolet ,Physics::Atomic and Molecular Clusters ,Physics::Atomic Physics ,Physical and Theoretical Chemistry ,Atomic physics ,0210 nano-technology ,Computer Science::Databases ,Helium - Abstract
The photoionization of helium ion in bichromatic circularly polarized XUV laser pulses is investigated by solving the time-dependent Schrӧdinger equation. It shows that the electron can reach the continuum at the same momentum by absorbing one high-energetic photon or two low-energetic photons sequentially, and these two pathways can interfere with each other. Moreover, the interference can induce the asymmetrical round and the spiral-loop photoelectron momentum distributions in bichromatic circularly laser fields without and with the time delay.
- Published
- 2019
25. Microstructure and tribocorrosion performance of nanocrystalline TiN graded coating on biomedical titanium alloy
- Author
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Gaowu Qin, Wen-fang Cui, Feng-juan Niu, and Yun-ling Tan
- Subjects
010302 applied physics ,Materials science ,Tribocorrosion ,Metals and Alloys ,Titanium alloy ,chemistry.chemical_element ,02 engineering and technology ,engineering.material ,021001 nanoscience & nanotechnology ,Geotechnical Engineering and Engineering Geology ,Condensed Matter Physics ,Microstructure ,01 natural sciences ,Nanocrystalline material ,Corrosion ,Coating ,chemistry ,Sputtering ,0103 physical sciences ,Materials Chemistry ,engineering ,Composite material ,0210 nano-technology ,Tin - Abstract
A nanocrystalline TiN graded coating was prepared on Ti6Al4V alloy by DC reactive magnetron sputtering method. The microstructure and mechanic properties of the coating were investigated. The electrochemical corrosion and tribocorrosion of the coated specimens in physiological environment were compared with those of Ti6Al4V substrate. The results show that the gradient distribution of nanocrystalline TiN is favorable for releasing the inner stress in the coating, which increases adhesion strength to 90 N. The compact structure and refined-grains of the coating result in the surface nanohardness of 28.5 GPa. The corrosion protection efficiency of the nanocrystalline TiN coating reaches 96.6%. The tribocorrosion resistance of the coating increases by 100 times in comparison with that of Ti6Al4V substrate. The high chemical stability and H3/E2 ratio (where H is hardness, and E is elastic modulus) of the nanocrystalline TiN coating are responsible for good corrosion and wear resistances.
- Published
- 2019
26. Implementation intention training for prospective memory in schizophrenia: A 3-month follow-up study
- Author
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Ying Li, Ya Wang, David L. Neumann, Raymond C.K. Chan, Eric F.C. Cheung, Shu-li Tao, Ji-fang Cui, Xiao-jing Qin, David Shum, Lu-lu Liu, and Tao Chen
- Subjects
Adult ,Male ,medicine.medical_specialty ,Memory, Episodic ,Psychological intervention ,Intention ,Neuropsychological Tests ,03 medical and health sciences ,0302 clinical medicine ,Intervention (counseling) ,Prospective memory ,Humans ,Medicine ,Social Behavior ,Biological Psychiatry ,Social functioning ,Memory Disorders ,business.industry ,Implementation intention ,Telephone call ,Middle Aged ,medicine.disease ,030227 psychiatry ,Psychiatry and Mental health ,Treatment Outcome ,Schizophrenia ,Psychotherapy, Group ,Physical therapy ,Female ,Schizophrenic Psychology ,business ,030217 neurology & neurosurgery ,Follow-Up Studies ,Month follow up - Abstract
The beneficial effect of implementation intentions (II) on prospective memory (PM) deficits in patients with schizophrenia has been reported. However, these studies were limited to brief interventions such that the transfer and long-term effects of II training remains unclear. This study examined whether a 10-session II programme could improve PM performance, social functioning and functional capacity in patients with schizophrenia immediately after training and at 3-month follow-up. Patients with schizophrenia (n = 42) recruited from the community were randomly assigned to II training (n = 21) or treatment as usual (TAU) (n = 21). Participants in the II group learned the verbal and imagery component of II and were encouraged to apply these strategies in their daily lives. We found that the II group performed better than the TAU group on computer-based PM tasks and a daily life PM task (telephone call at specified date and time) at post-treatment and at 3-month follow-up. The II group also exhibited better working ability than the TAU group at post-treatment. Our results suggest that the II intervention programme may have lasting beneficial effects in PM performance and significant transfer effects to functional capacity in schizophrenia patients.
- Published
- 2019
27. Multiple-Fingerprint and Spectrum-Effect Relationship of Bioactivity from Codonopsis Pilosula Polysaccharide
- Author
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Jingmin Fan, Fang Cui, Ruibin Bai, Yingrui Gao, Qiaohong Xu, Wenbo Shi, Wen Li, and Fangdi Hu
- Subjects
History ,Polymers and Plastics ,Business and International Management ,Industrial and Manufacturing Engineering - Published
- 2021
28. Surface engineering of Co3O4 nanoribbons forming abundant oxygen-vacancy for advanced supercapacitor
- Author
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Xin Qi, Fang Cui, Jiajia Zhang, Tieyu Cui, and Qinghai Ma
- Subjects
Supercapacitor ,Materials science ,Oxide ,General Physics and Astronomy ,Surfaces and Interfaces ,General Chemistry ,Conductivity ,Surface engineering ,Condensed Matter Physics ,Electrochemistry ,Capacitance ,Redox ,Surfaces, Coatings and Films ,chemistry.chemical_compound ,Electrical resistance and conductance ,chemistry ,Chemical engineering - Abstract
The development of high-efficiency metal oxide electrode materials with high reaction kinetics and excellent conductivity are a cutting-edge strategy to obtain high-performance energy storge devices. Forming oxygen vacancy on the surface of the metal oxide tune electronic structure is a feasible approach to boost the electroactive of metal oxides for supercapacitor. Herein, an effective solution reduction method is reported for tuning the electronic structure of Co3O4 nanoribbons reacting with NaBH4 to enhance the faradaic redox reaction for high electrochemical performance. The vacancy-rich defects can endow more electroactive sites and reduce the electrical resistance for the enhanced supercapacitor performance. Therefore, compared to pristine Co3O4 (347.4 F g-1), the reduced Co3O4 (R-Co3O4) shows a high specific capacitance (Cs, 464.9 F g-1) and a reduced charge transfer resistance. The asymmetric supercapacitor (ASC, R-Co3O4// active carbon) exhibits an energy density of 18.6 Wh kg-1 at the power density of 400 W kg-1 and excellent cycling stability. Such a feasible approach realizes the electronic tuning by creating oxygen vacancy that provides sufficient active sites and activates the fast faradaic redox reaction with enhanced energy storge ability of redox-active electrode materials.
- Published
- 2022
29. Boosted artificial intelligence model using improved alpha-guided grey wolf optimizer for groundwater level prediction: Comparative study and insight for federated learning technology
- Author
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Fang Cui, Zainab Abdulelah Al-Sudani, Geehan Sabah Hassan, Haitham Abdulmohsin Afan, Sumaiya Jarin Ahammed, and Zaher Mundher Yaseen
- Subjects
Water Science and Technology - Published
- 2022
30. Self-templating synthesis of hierarchical porous carbon with multi-heteroatom co-doping from tea waste for high-performance supercapacitor
- Author
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Haitao Xi, Peng Chen, Jiajia Zhang, Qinghai Ma, Fang Cui, and Tieyu Cui
- Subjects
Supercapacitor ,Materials science ,Renewable Energy, Sustainability and the Environment ,Carbonization ,Doping ,Heteroatom ,Energy Engineering and Power Technology ,chemistry.chemical_element ,Electrolyte ,Electrochemistry ,Chemical engineering ,chemistry ,Electrical and Electronic Engineering ,Pyrolysis ,Carbon - Abstract
Exploring porous carbon (PC)-based materials from low-cost, renewable precursors has always been a challenging objective, since they meet the demands of next-generation supercapacitors and electrochemical devices. Herein, hierarchical multi-heteroatoms co-doped PC (MHPC) materials are successfully achieved by the carbonization and activation of tea waste that used as the self-template. The natural structure of the tea leaves combined with the activation strategy favor the formation of special hierarchical MHPC materials, which are constructed by ultrathin MHPC nanosheets. In addition, the heteroatomic doped carbon derived from organic compounds in tea leaves can act as an ideal precursor to fabricate the resultant heteroatomic functionalized carbon nanosheets. Such heteroatoms content of carbon nanosheets are adjustable by altering pyrolysis condition to effectively enhance the electrochemical performance of PC. After activation by KOH, the as-prepared MHPC, especially MHPC-3 (weight ratio of KOH/pre-carbonized tea waste is 3:1) has a superior supercapacitance of up to 170 and 132 F g−1 at current density of 0.5 and 10 A g−1 in KOH electrolyte, and an excellent capacitance retention of ∼94.8% over 14,000 cycles at 3 A g−1. The result reported here provides valuable guidelines of high-performance energy storge devices from natural sources at the industrial scale.
- Published
- 2022
31. Innovative health risk assessment of heavy metals in Chinese herbal medicines based on extensive data
- Author
-
Zuo, Tian-Tian, primary, Jin, Hong-Yu, additional, Zhang, Lei, additional, Liu, Yong-Li, additional, Nie, Jing, additional, Chen, Bi-lian, additional, Fang, Cui-fen, additional, Xue, Jian, additional, Bi, Xue-yan, additional, Zhou, Li, additional, Shen, Ming-rui, additional, Shi, Shang-mei, additional, and Ma, Shuang-Cheng, additional
- Published
- 2021
- Full Text
- View/download PDF
32. Energy evolution mechanism in process of Sandstone failure and energy strength criterion
- Author
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Yunfei Wang and Fang Cui
- Subjects
Range (particle radiation) ,Materials science ,Elastic energy ,02 engineering and technology ,Mechanics ,Dissipation ,010502 geochemistry & geophysics ,Overburden pressure ,01 natural sciences ,Surface energy ,Energy storage ,Physics::Geophysics ,020501 mining & metallurgy ,Condensed Matter::Materials Science ,Geophysics ,0205 materials engineering ,Deformation (engineering) ,Ductility (Earth science) ,0105 earth and related environmental sciences - Abstract
To reveal the inherent relation between energy change and confining pressure during the process of sandstone damage, and its characteristics of energy storage and energy dissipation in different deformation stage. Obtaining the mechanical parameters by testing the Sandstone of two1 coal seam roof under uniaxial compression in Zhaogu coalmine, using Particle Flow Code (PFC) and fish program to get the meso-mechanical parameters, studying Sandstone energy evolution mechanism under different confining pressures, and deducing energy strength criterion based on energy principle of rock failure, some main researching results are reached as follows: with the increasing of confining pressure, the Sandstone yield stage and ductility increases, but brittleness decreases; Under higher confining pressure, the elastic strain energy of Sandstone before peak approximately keeps constant in a certain strain range, and rock absorbs all the energy which converts into surface energy required for internal damage development; Under lower confining pressure, Sandstone no longer absorbs energy with increasing strain after peak under lower confining pressure, while it sequentially absorbs energy under higher confining pressure; Under lower confining pressure, the energy Sandstone before peak absorbed mainly converts into elastic strain energy, while under higher confining pressure, dissipation energy significantly increases before peak, which indicates that the degree rock strength loss is higher under higher confining pressure; with the increasing of confining pressure, the limit of elastic strain energy increases and there exists a favourable linear variation relationship; At the peak point, the ratio of elastic strain energy to total energy of Sandstone nonlinearly decreases, while the ratio of dissipation energy to total energy nonlinearly increases with the increasing of confining pressure; According to energy evolution mechanism of rock failure, an energy strength criterion is derived. The criterion equation includes lithology constants and three principal stresses, and its physical meaning is clear. This criterion has an evident advantage than Hoek-Brown and Drucker-Prager criterion in calculation accuracy and can commendably describe rock failure characteristics.
- Published
- 2018
33. Instability characteristics of the cracked roof rock beam under shallow mining conditions
- Author
-
Linlin Ge, Fang Cui, Shuren Wang, Zhengsheng Zou, and Yanhai Zhao
- Subjects
lcsh:TN1-997 ,Numerical analysis ,0211 other engineering and technologies ,Rotation around a fixed axis ,Energy Engineering and Power Technology ,Vertical load ,Thrust ,02 engineering and technology ,Geotechnical Engineering and Engineering Geology ,Instability ,020401 chemical engineering ,Geochemistry and Petrology ,Deflection (engineering) ,Geotechnical engineering ,Vertical displacement ,0204 chemical engineering ,Roof ,lcsh:Mining engineering. Metallurgy ,Geology ,021101 geological & geomatics engineering - Abstract
To establish the movement relationship for the roof breaking under shallow mining conditions, the mechanical model of the roof rock beam was built, then the structure instability process of the roof rock beam was analyzed. The changing criterion of the vertical displacement was established and the relationship between the deflection and the rotary motion of roof block was determined. Regarding a mining face in Shangwan Mine, the responsing laws of the deflection and horizontal thrust of the roof rock beam were obtained through FLAC3D numerical analysis. The results show that the structure instability of the cracked roof rock beam depends on the interaction between the vertical load and the horizontal thrust. For the roof rock beam, when the vertical load keeps constant, the horizontal thrust fluctuating rises with increasing deflection. The horizontal thrust increases constantly with the deeper buried depth and the smaller span. Keywords: Shallow mining, Working face, Roof rock beam, Structure stability, Horizontal thrust
- Published
- 2018
34. A label-free and lectin-based sandwich aptasensor for detection of carcinoembryonic antigen
- Author
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Li-Li Chen, Meng-Meng Li, Shuangfei Fan, Qiong-Lin Wang, Xiaojie Song, Hui-Fang Cui, and Zong-Yi Li
- Subjects
Aptamer ,02 engineering and technology ,01 natural sciences ,Carcinoembryonic antigen ,Materials Chemistry ,Electrical and Electronic Engineering ,Instrumentation ,Tumor marker ,Detection limit ,biology ,Chemistry ,010401 analytical chemistry ,Metals and Alloys ,Lectin ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Molecular biology ,digestive system diseases ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Linear range ,Concanavalin A ,biology.protein ,0210 nano-technology ,Biosensor - Abstract
Carcinoembryonic antigen (CEA), a glycoprotein, is a wide-spectrum tumor marker for cancer diagnosis. Developing simple, stable, and low-cost methods for CEA detection is of great importance. In this work, a novel, label-free, and antibody-free electrochemical sandwich CEA biosensor was developed based on concanavalin A (ConA) and a DNA aptamer against CEA. Horse radish peroxidase (HRP) was labeled on the sandwich structure for signal production and amplification. Both the CEA and the HRP bind to ConA through sugar-lectin interactions. Under optimum conditions, the detection linear range was from 5 to 40 ng mL−1 CEA, with a detection limit of 3.4 ng mL−1, lower than the threshold level in human serum for cancer patients (∼10 ng mL−1). The biosensor is reproducible, accurate, specific, and stable, with RSD value of 3% for inter-biosensors, and relative error of
- Published
- 2018
35. Dynamics of an SAITS alcoholism model on unweighted and weighted networks
- Author
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Hai-Feng Huo, Hong Xiang, and Fang-Fang Cui
- Subjects
010101 applied mathematics ,Statistics and Probability ,0103 physical sciences ,Applied mathematics ,0101 mathematics ,Condensed Matter Physics ,Compartment (pharmacokinetics) ,01 natural sciences ,Basic reproduction number ,010305 fluids & plasmas ,Mathematics - Abstract
A novel SAITS alcoholism model on networks is introduced, in which alcoholics are divided into light problem alcoholics and heavy problem alcoholics. Susceptible individuals can enter into the compartment of heavy problem alcoholics directly by contacting with light problem alcoholics or heavy problem alcoholics and the heavy problem alcoholics who receive treatment can relapse into the compartment of heavy problem alcoholics are also considered. First, the dynamics of our model on unweighted networks, including the basic reproduction number, existence and stability of equilibria are studied. Second, the models with fixed weighted and adaptive weighted networks are introduced and investigated. At last, some simulations are presented to illustrate and extend our results. Our results show that it is very important to treat alcoholics to quit the drinking.
- Published
- 2018
36. Plastic-deformation-driven SiC nanoparticle implantation in an Al surface by laser shock wave: Mechanical properties, microstructure characteristics, and synergistic strengthening mechanisms
- Author
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Kaiyu Luo, Cui Xigui, Fang Cui, Yongfeng Lu, Raif Farkouh, Jianzhong Zhou, Xu-Dong Ren, C.Y. Cui, Li Xiaodong, and Jinzhong Lu
- Subjects
010302 applied physics ,Materials science ,Mechanical Engineering ,02 engineering and technology ,021001 nanoscience & nanotechnology ,Microstructure ,01 natural sciences ,Focused ion beam ,Shock (mechanics) ,chemistry.chemical_compound ,chemistry ,Mechanics of Materials ,Residual stress ,0103 physical sciences ,Silicon carbide ,General Materials Science ,Composite material ,Dislocation ,0210 nano-technology ,Elastic modulus ,Strengthening mechanisms of materials - Abstract
Laser shock-wave-driven nanoparticle implantation (LSWNI) in alloys is a novel surface strengthening technique based on plastic deformation induced by laser shock processing and the excellent properties of hard-phase nanoparticles. In the present work, 50–100 nm silicon carbide (SiC) nanoparticles were successfully implanted into commercially pure aluminum (Al) substrates under the effect of a laser shock wave. After the implantation, stable nanoparticle-reinforced layers were fabricated, and their microstructural response and grain refinement were characterized by X-ray diffraction (XRD), focused ion beam (FIB), and transmission electron microscopy (TEM). In addition, the mechanical properties, including residual stress, nanohardness, elastic modulus, and wear resistance, were investigated. Experimental results showed that Al samples subjected to LSWNI exhibited superior mechanical properties because of the good combination between the gradient microstructure induced by plastic deformation and the gradient distribution of the implanted SiC nanoparticles along the depth direction. Therefore, the overall strengthening effect generated by the LSWNI process can be described as two different modes: (i) the gradient microstructure induced by plastic deformation contributed mainly to the enhancement of residual stress and nanohardness, and (ii) the gradient distribution of the implanted SiC nanoparticles was dedicated primarily to the improvement of the wear resistance. As indicated by the strengthening effect during the LSWNI process, three competing strengthening mechanisms, namely, SiC nanoparticle strengthening, refined grain strengthening, and dislocation strengthening, existed in the gradient-reinforced layers. The detailed contribution of each mechanism to the overall properties of the reinforced layer was determined using the modified Clyne computational model and was described herein. Finally, the wear mechanism of the reinforced layer fabricated by the LSWNI process is revealed.
- Published
- 2018
37. Hierarchically porous WO3 microstructures with networks for acetylene sensing application
- Author
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Fang Cui, Lingfeng Jin, Weigen Chen, and He Zhang
- Subjects
Imagination ,Nanostructure ,Chemical substance ,Materials science ,Transformer oil ,Mechanical Engineering ,media_common.quotation_subject ,Nanotechnology ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,0104 chemical sciences ,law.invention ,Mechanics of Materials ,law ,General Materials Science ,Nanorod ,0210 nano-technology ,Porosity ,Transformer ,Science, technology and society ,media_common - Abstract
As a typical failure characteristic gas dissolved in transformer oil, C2H2 has a great significance to evaluate the running state of transformer by monitoring its content. Previous reports mainly focus on organizing WO3 nanoscale building blocks into well-defined 3D nanostructures. However, little attention has been paid to different 1D building blocks on the impact of gas sensing properties. In this work, nanorod and nanowire-assembled WO3 porous networks were controllably synthesized, which were applied to C2H2 detection. In comparison, sensor based on the latter exhibited superior performance than the former one, which seems indicate the significance of electronic transport in gas sensing process. It is proposed that the former possesses numerous nanojunctions between nanorods, while the latter has features with larger capping area and less junction density.
- Published
- 2018
38. Bagging classification tree-based robust variable selection for radial basis function network modeling in metabonomics data analysis
- Author
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Haiyan Fu, Yan-Ping Zhou, Meng-Ying Tu, Yan-Fang Cui, Yan-Jiao Fu, Hui Gu, and Lu Xu
- Subjects
0301 basic medicine ,Radial basis function network ,Computer science ,Basis function ,Feature selection ,Machine learning ,computer.software_genre ,01 natural sciences ,Analytical Chemistry ,Chemometrics ,03 medical and health sciences ,Robustness (computer science) ,Spectroscopy ,Reliability (statistics) ,business.industry ,Process Chemistry and Technology ,Decision tree learning ,010401 analytical chemistry ,0104 chemical sciences ,Computer Science Applications ,Variable (computer science) ,030104 developmental biology ,Artificial intelligence ,business ,computer ,Software - Abstract
Complex datasets can be routinely produced from modern analytical platforms in metabonomics surveys, which brings enormous challenges to existing chemometrics tools. In the current study, inspired by the characteristic of classification tree (CT) in automatically selecting the most informative variables and measuring their importance, the potential of bagging in improving the reliability and robustness of a single model, and the promising modeling performance of radial basis function network (RBFN), we designed a new chemometrics tool, i.e., bagging classification tree-radial basis function network (BAGCT-EBFN), for metabonomics data analysis. In BAGCT-RBFN, a series of parallel CT models were firstly established based on the idea of bagging (BAGCT). The informative variables can be successfully spied via inspecting the variable importance values over all CTs in BAGCT. Then, RBFN was utilized to relate the identified informative variables to the class memberships. To demonstrate the practical application of BAGCT-RBFN in metabonomics, an H-1 NMR-based metabonomics dataset associated with lung cancer was applied. The results showed that BAGCT-RBFN can find a shortlist of discriminatory variables with reliability while attain more satisfactory classification accuracy than traditional CT and RBFN.
- Published
- 2018
39. A highly stable acetylcholinesterase biosensor based on chitosan-TiO2-graphene nanocomposites for detection of organophosphate pesticides
- Author
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Hui-Fang Cui, Wen-Wen Wu, Ting-Ting Zhang, Xiaojie Song, Meng-Meng Li, and Yuanxu Lv
- Subjects
Detection limit ,Chromatography ,Graphene ,Biomedical Engineering ,Biophysics ,02 engineering and technology ,General Medicine ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,law.invention ,Matrix (chemical analysis) ,Chitosan ,chemistry.chemical_compound ,Adsorption ,Linear range ,chemistry ,law ,Dichlorvos ,Electrochemistry ,0210 nano-technology ,Biosensor ,Biotechnology ,Nuclear chemistry - Abstract
A highly stable electrochemical acetylcholinesterase (AChE) biosensor for detection of organophosphorus pesticides (OPs) was developed simply by adsorption of AChE on chitosan (CS), TiO2 sol-gel, and reduced graphene oxide (rGO) based multi-layered immobilization matrix (denoted as CS@TiO2-CS/rGO). The biosensor fabrication conditions were optimized, and the fabrication process was probed and confirmed by scanning electron microscopy and electrochemical techniques. The matrix has a mesoporous nanostructure. Incorporation of CS and electrodeposition of a CS layer into/on the TiO2 sol-gel makes the gel become mechanically strong. The catalytic activity of the AChE immobilized CS@TiO2-CS/rGO/glassy carbon electrode to acetylthiocholine is significantly higher than those missing any one of the component in the matrix. The detection linear range of the biosensor to dichlorvos, a model OP compound, is from 0.036μM (7.9 ppb) to 22.6μM, with a limit of detection of 29nM (6.4 ppb) and a total detection time of about 25min. The biosensor is very reproducibly and stable both in detection and in storage, and can accurately detect the dichlorvos levels in cabbage juice samples, providing an efficient platform for immobilization of AChE, and a promisingly applicable OPs biosensor with high reliability, simplicity, and rapidness.
- Published
- 2018
40. Carbon dots-based red fluorescence nanoprobe for caspase-1 activity assay and living cell imaging
- Author
-
Hui-Fang Cui, Xiaojie Song, Qi-Yan Lv, and Gai-Gai Wang
- Subjects
chemistry.chemical_classification ,Detection limit ,Metals and Alloys ,Nanoprobe ,Peptide ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Cleavage (embryo) ,01 natural sciences ,Acceptor ,Fluorescence ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,chemistry ,Covalent bond ,Materials Chemistry ,Biophysics ,Electrical and Electronic Engineering ,0210 nano-technology ,Instrumentation ,Intracellular - Abstract
The development of sensitive and convenient strategies for monitoring intracellular caspase-1 activity is of great significance. Herein, a novel fluorescence nanoprobe for caspase-1 activity determination was constructed based on surface energy transfer (SET) between red-emissive carbon dots (RCDs) as a donor, and Au nanorods (AuNRs) as an acceptor. The donor/acceptor pair were covalently bridged with a peptide containing a caspase-1 cleavage site (YVAD) at middle. The stability and dispersivity of the AuNR-Pep-RCD nanoprobe was realized/enhanced by pretreating the AuNRs with PEG-SH. Active caspase-1 cleaves the YVAD site, releasing RCDs and recovering the fluorescence. Synergic effect of the red-emission, sensitive and selective cleavage, and excellent SET efficiency contribute to the nanoprobe with high sensitivity and selectivity, especially in biological samples. More importantly, the nanoprobe can be uptaken by living cells, capable of in-situ intracellular caspase-1 activity imaging. The fluorescence recovery is linearly correlated with caspase-1 activity in the range of 5‒300 ng·mL−1 (2.5 × 10−5‒1.3 × 10−3 U·mL−1), with a limit of detection of 1.76 ng·mL−1 (8.8 × 10-6 U·mL−1). In particular, the fluorescence nanoprobe can accurately detect caspase-1 activity in cells extract, and sensitively probe the caspase-1 activation treatment and inhibition treatment for the intracellular caspase-1 activity levels.
- Published
- 2021
41. Life review therapy enhances mental time travel in patients with schizophrenia
- Author
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Ya Wang, Bin Bi, Jie-chun Gan, Tao Chen, Lu-lu Liu, Ji-fang Cui, Gui-fang Chen, David Shum, David L. Neumann, Xiao-jing Qin, and Raymond C.K. Chan
- Subjects
Adult ,Male ,medicine.medical_specialty ,Adolescent ,Chronesthesia ,Emotions ,education ,Personal Satisfaction ,Neuropsychological Tests ,050105 experimental psychology ,Young Adult ,03 medical and health sciences ,Cognition ,0302 clinical medicine ,Internal medicine ,medicine ,Humans ,Verbal fluency test ,Semantic memory ,0501 psychology and cognitive sciences ,Emotional expression ,Biological Psychiatry ,Verbal Behavior ,05 social sciences ,Life satisfaction ,Middle Aged ,medicine.disease ,Psychiatry and Mental health ,Schizophrenia ,Female ,Schizophrenic Psychology ,Psychology ,Life review ,030217 neurology & neurosurgery ,Clinical psychology - Abstract
Mental Time Travel (MTT) is the ability of individuals to project themselves to the past or to the future. Studies have shown that schizophrenia (SZ) patients are impaired in MTT. The present study aimed to examine whether MTT in patients with SZ can be improved through Life Review Therapy. Fifty patients with SZ were randomly assigned to the training (SZ-training) or control (SZ-control) group. Whereas the SZ-training group received four-week Life Review Therapy in addition to conventional treatment, the SZ-control group only received conventional treatment. MTT, emotional status, life satisfaction and cognitive functions were assessed before and after the training. We also recruited 25 matched healthy controls to complete all the assessments at baseline. After training, the SZ-training group showed higher specificity and more field perspective than the SZ-control group. No significant difference was found between the SZ-training group post-training assessment and the healthy controls. The SZ-training group also showed significant improvements in emotional expression, semantic memory and verbal fluency, but the SZ-control group did not show such improvements. These results indicated that Life Review Therapy is effective in improving MTT of SZ patients.
- Published
- 2017
42. Corrosion resistance and antibacterial activity of Ti-N-O coatings deposited on dental titanium alloy
- Author
-
Gaowu Qin, Wen-Fang Cui, Weilong Wang, and Yong-Cun Bao
- Subjects
Materials science ,Passivation ,Alloy ,chemistry.chemical_element ,02 engineering and technology ,engineering.material ,010402 general chemistry ,01 natural sciences ,Corrosion ,X-ray photoelectron spectroscopy ,Coating ,Materials Chemistry ,Titanium alloy ,Surfaces and Interfaces ,General Chemistry ,equipment and supplies ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,0104 chemical sciences ,Surfaces, Coatings and Films ,Chemical engineering ,chemistry ,Physical vapor deposition ,engineering ,0210 nano-technology ,Tin - Abstract
The corrosion resistance and antibacterial activity of dental metal materials are important service performances. In this paper, the TiN and Ti-N-O coatings with different chemical compositions were deposited on Ti6Al4V alloy by physical vapor deposition (PVD). The phase structure, surface morphology and elemental distribution of the Ti-N-O coatings were characterized by XRD, XPS, SEM and EPMA. The electrochemical corrosion behavior of the Ti-N-O coatings in acidic and fluoride-containing artificial saliva was investigated. The antibacterial activity of the coated Ti alloy was evaluated by an in vitro antibacterial test. The results show that with increasing O2 flow rate in the reaction atmosphere, the phase compositions of the Ti-N-O coatings gradually change from TiN to TiNxOy, Ti2O3, TiO2 and Ti3O5. The Ti-N-O coatings show good passivation behavior. Particularly, when the ratio of N2 and O2 flow rate is 2:1, the corrosion current density of the Ti-N-O coated specimen in acid (pH = 5.2) solution is only 6.0 × 10−8 A/cm2. In an acidic solution containing 0.1% NaF, the passivation potential of the Ti-N-O coatings exceeds +1.0 V, and the corrosion resistance is exceeds that of a TiN coating. When the ratio of N2 and O2 flow rate is 1:1, the antibacterial rate of the Ti-N-O coating against Staphylococcus aureus approaches 90%.
- Published
- 2021
43. A novel assay strategy based on isothermal amplification and cascade signal amplified electrochemical DNA sensor for sensitive detection of Helicobacter pylori
- Author
-
Yu-Yang Huo, Man-Man Lv, Qi-Yan Lv, Jing Fu, Xiaojie Song, and Hui-Fang Cui
- Subjects
Transfer DNA ,010401 analytical chemistry ,Deoxyribozyme ,Loop-mediated isothermal amplification ,02 engineering and technology ,Amplicon ,021001 nanoscience & nanotechnology ,01 natural sciences ,Molecular biology ,DNA sequencing ,0104 chemical sciences ,Analytical Chemistry ,chemistry.chemical_compound ,genomic DNA ,chemistry ,Primer (molecular biology) ,0210 nano-technology ,Spectroscopy ,DNA - Abstract
A novel and sensitive Helicobacter pylori assay strategy based on linear isothermal amplification reaction (LIAR) and DNAzymes catalyzed DNA sensor was developed. A 17 nt target DNA (tDNA) specific in the H. pylori genome was selected and used as primer in the LIAR. A template DNA was designed to produce an amplicon with Mg2+-dependent and RNA-cleaving DNAzyme (Md-Dz) activity. The amplicon (i.e. Md-Dz) was then detected with the DNA sensor. The DNA sensor was fabricated simply through immobilization of a hairpin DNA that contains both Md-Dz substrate and G-quadruplex DNAzyme (Gq-Dz), on gold electrodes. The Gq-Dz possesses peroxidase activity, catalyzing the electro-redox of the electrochemical signal probe hydroquinon. The LIAR, Md-Dz catalytic reaction, and DNA sensor fabrication and detection processes were characterized and optimized. The LIAR amplification efficiency is as high as ~5 × 105 fold, and the assay strategy is very sensitive, selective and repetitive. The differential pulse voltammetry (DPV) detection signals linearly correlate to the logarithmic tDNA concentration in the range of 0.1–10,000 fM, with a limit of detection (LOD) of 34 aM. The detection linear range for H. pylori genomic DNA is 2.1–67.2 pg, with an LOD of 1.3 pg. Muted DNA sequences and other pathogenic bacteria did not result in interferences. In addition, the DNA sensor is very stable in storage. More importantly, the DNA sensor and the assay strategy could be universally applicable to detect any biological sample and short DNA sequence of interests.
- Published
- 2021
44. Innovative health risk assessment of heavy metals in Chinese herbal medicines based on extensive data
- Author
-
Zuo, Tian-Tian, primary, Jin, Hong-Yu, additional, Zhang, Lei, additional, Liu, Yong-Li, additional, Nie, Jing, additional, Chen, Bi-lian, additional, Fang, Cui-fen, additional, Xue, Jian, additional, Bi, Xue-yan, additional, Zhou, Li, additional, Shen, Ming-rui, additional, Shi, Shang-mei, additional, and Ma, Shuang-Cheng, additional
- Published
- 2020
- Full Text
- View/download PDF
45. A rhodamine B-based turn on fluorescent probe for selective recognition of mercury(II) ions
- Author
-
Chen-Fang Cui, Yang Jiao, Xianchao Jia, Chunying Duan, and Xu Gao
- Subjects
010405 organic chemistry ,Metal ions in aqueous solution ,chemistry.chemical_element ,Carbon-13 NMR ,010402 general chemistry ,Photochemistry ,01 natural sciences ,Fluorescence ,0104 chemical sciences ,Ion ,Mercury (element) ,Inorganic Chemistry ,chemistry.chemical_compound ,chemistry ,Materials Chemistry ,Rhodamine B ,Proton NMR ,Physical and Theoretical Chemistry ,Selectivity - Abstract
The recognition of mercury(II) ions content in the environment and organisms is of great significance for maintaining the health of the organism and preventing diseases induced by mercury(II) ions. Herein a fluorescent probe which includes rhodamine B and acenaphtho[1,2-b]quinoxaline-9-amin has been designed and synthesized for recognizing mercury(II) ions. The structure of RB-AQ was confirmed by 1H NMR, 13C NMR, HR-MS analyses and single X-ray crystallography. The fluorescent probe RB-AQ exhibited an obvious “turn-on” fluorescence enhancement for mercury(II) ions at 586 nm. RB-AQ showed good recognization capability and selectivity toward mercury(II) ions over other interfering metal ions in solution. Further, the probe has mercury(II) ions imaging capability in cells and zebrafish.
- Published
- 2021
46. 18 F-fallypride PET-CT of dopamine D2/D3 receptors in patients with sporadic amyotrophic lateral sclerosis
- Author
-
Gangming Shu, Wenjia Zhu, Yuting Ren, Ying Zhang, Zhe Guo, Jinming Zhang, Xiaojun Zhang, Xiaoling Fu, Fei Yang, Li Ling, Xusheng Huang, Zhaohui Chen, Fang Cui, and Xiaolan Zhang
- Subjects
0301 basic medicine ,Pathology ,medicine.medical_specialty ,Montreal Cognitive Assessment ,Striatum ,Nucleus accumbens ,medicine.disease ,Statistical parametric mapping ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,Neurology ,Superior frontal gyrus ,Dopamine receptor ,Dopamine receptor D2 ,Anesthesia ,medicine ,Neurology (clinical) ,Amyotrophic lateral sclerosis ,Psychology ,030217 neurology & neurosurgery - Abstract
Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disease with unclear pathogenesis. To date, there have been no reports regarding the distribution of dopamine receptors outside the striatum in ALS patients. In this study, 17 ALS patients and 11 healthy controls underwent 18F-fallypride positron emission tomography/computed tomography (PET/CT) and completed cognitive-related tests for assessment of the distribution of dopamine receptors inside and outside the striatum in ALS and evaluation of the relationships between the distribution of dopamine receptors and cognitive function. The results showed that ALS patients showed significantly lower scores only in language and delayed recall of Montreal Cognitive Assessment scale. There were no significant differences between the two groups in the cognitive-related test results. Statistical parametric mapping (SPM) data showed that the binding affinity of 18F-fallypride in ALS patients was decreased in the bilateral nucleus accumbens septi, bilateral frontal lobes, and the superior frontal gyrus, left temporal lobe, and angular gyrus regions. In conclusion, the levels of dopamine receptors were significantly decreased in some areas outside the striatum in patients with ALS, which may contribute to mild cognitive impairment in ALS patients.
- Published
- 2017
47. Working memory load modulates the neural response to other’s pain: Evidence from an ERP study
- Author
-
Fang Cui, Jiaping Cheng, Xiangru Zhu, and Yuejia Luo
- Subjects
Male ,Cognitive evaluation theory ,Working memory ,General Neuroscience ,05 social sciences ,Perspective (graphical) ,Pain ,Electroencephalography ,Cognition ,050105 experimental psychology ,Arousal ,Young Adult ,03 medical and health sciences ,Memory, Short-Term ,0302 clinical medicine ,Time course ,Humans ,Attention ,Female ,0501 psychology and cognitive sciences ,Empathy ,Psychology ,Evoked Potentials ,030217 neurology & neurosurgery ,Cognitive psychology - Abstract
The present study investigated the time course of processing other's pain under different conditions of working memory (WM) load. Event-related potentials (ERPs) were recorded while the participants held two digits (low WM load) or six digits (high WM load) in WM and viewed pictures that showed others who were in painful or non-painful situations. Robust WM-load×Picture interactions were found for the N2 and LPP components. In the high WM-load condition, painful pictures elicited significantly larger amplitudes than non-painful pictures. In the low WM load condition, the difference between the painful and non-painful pictures was not significant. These ERP results indicate that WM load can influence both the early automatic N2 component and late cognitive LPP component. Compared with high WM load, low WM load reduced affective arousal and emotional sharing in response to other's pain and weakened the cognitive evaluation of task irrelevant stimuli. These findings are explained from the load theory perspective.
- Published
- 2017
48. Preliminary study of visual perspective in mental time travel in schizophrenia
- Author
-
Ya Wang, Xiaohong Hong, Yi Wang, Qing Zhao, Ji-fang Cui, and Raymond C.K. Chan
- Subjects
Adult ,Male ,050103 clinical psychology ,medicine.medical_specialty ,Chronesthesia ,behavioral disciplines and activities ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,mental disorders ,medicine ,Humans ,0501 psychology and cognitive sciences ,Psychiatry ,Biological Psychiatry ,Recall ,05 social sciences ,Perspective (graphical) ,Psychiatry and Mental health ,Case-Control Studies ,Mental Recall ,Imagination ,Schizophrenia ,Visual Perception ,Female ,Schizophrenic Psychology ,Cues ,Psychology ,030217 neurology & neurosurgery - Abstract
This study explored specificity and visual perspective of mental time travel in schizophrenia. Fifteen patients with schizophrenia and 18 controls were recruited. Participants were asked to recall or imagine specific events according to cue words. Results showed that schizophrenia patients generated fewer specific events than controls, the recalled events were more specific than imagined events. Schizophrenia adopted less field perspective and more observer perspective than controls. These results suggested that patients with schizophrenia were impaired in mental time travel both in specificity and visual perspective. Further studies are needed to identify the underlying mechanisms.
- Published
- 2017
49. Genipin cross-linked blue Lys-FA nanoparticles for targeted visible glioma cell staining and drug delivery
- Author
-
Xiaojie Song, Hongmin Liu, Hui-Fang Cui, Kangli Lan, and Qi-Yan Lv
- Subjects
Fluorescence-lifetime imaging microscopy ,Chemistry ,technology, industry, and agriculture ,Pharmaceutical Science ,02 engineering and technology ,021001 nanoscience & nanotechnology ,030226 pharmacology & pharmacy ,Fluorescence spectroscopy ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Drug delivery ,Genipin ,Zeta potential ,Biophysics ,Nanomedicine ,Nanocarriers ,0210 nano-technology ,Cytotoxicity - Abstract
Design and fabrication of multifunctional nano-carrier is a promising tool in the field of nanomedicine for glioma theranostics. In this study, blue color nanoparticles with targeted tumor cell staining and drug delivery capabilities were simply fabricated by crosslinking lysine (Lys) and lysine-folic acid (Lys-FA) mixture with genipin as the crosslinking agent through a reversed microemulsion method. Doxorubicin (DOX) as the model drug was loaded through electrostatic interaction. The nanoparticles before (Lys-FA NPs) and after (Lys-FA/DOX NPs) loading of DOX were characterized by ultraviolet–visible (UV–Vis) spectroscopy, Fourier transform infrared spectroscopy (FTIR), dynamic laser light scattering (DLS), transmission electron microscopy (TEM), and fluorescence spectroscopy. Ultimately, the glioma cell staining ability of Lys-FA NPs and cytotoxicity of Lys-FA/DOX NPs were tested in vitro. The results showed that the particle size of Lys-FA NPs can be tuned by adjusting the ratio of Lys to Lys-FA simply. The Lys-FA NPs exhibited dark blue and the blue color is stable under different pH values and temperatures. The feature makes the staining glioma cell pellets visible to naked-eyes. The model drug DOX was loaded on Lys-FA NPs indicated by the increase of size and zeta potential, and change of optical properties. The DOX loaded on the Lys-FA NPs can be sustainedly released, other than burst release. Encouragingly, the Lys-FA NPs can deliver DOX into cells and dramatically reduce cell viability, as proved by U87 cell cytotoxicity analysis and confocal fluorescence imaging. In addition, the Lys-FA NPs (≤2.5 mg mL−1) are nontoxic to CHO cells. In a short, the blue color Lys-FA NPs can visibly stain glioma cell pellets and deliver DOX into glioma cells, which can potentially be applied as a multifunctional nanocarrier for tumor imaging and drug delivery.
- Published
- 2021
50. A multimode aptasensor based on hollow gold nanoparticles and structure switching of aptamer: Fast and sensitive detection of carcinoembryonic antigen
- Author
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Zong-Yi Li, Qiong-Lin Wang, Xiaojie Song, Chun-Ling Li, Hui-Fang Cui, and Qi-Yan Lv
- Subjects
Detection limit ,QA71-90 ,Chromatography ,biology ,Carcinoembryonic antigen detection ,Chemistry ,Aptamer ,DNA aptamer ,Structure switching ,Instruments and machines ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials ,Hollow gold nanoparticles ,Absorbance ,Carcinoembryonic antigen ,Colloidal gold ,Computer Science (miscellaneous) ,biology.protein ,Tumor marker ,Differential pulse voltammetry ,Signal amplification ,Electrical and Electronic Engineering ,Surface plasmon resonance ,Instrumentation ,Biosensor - Abstract
A fast and sensitive carcinoembryonic antigen (CEA) aptasensor with multiple detection modes was developed. It is based on hollow gold nanoparticles (HGNPs) and horse radish peroxidase (HRP) as both labels and signal amplification elements. In fabrication, capture DNA (cpDNA) was modified on magnetic beads, and reporter DNA (rpDNA) and HRP were co-modified on HGNPs. A combination DNA, containing a DNA aptamer (GAC-P) segment, hybridized with cpDNA and rpDNA, forming a satellite-structured biosensor. In response to CEA, the aptamer switches its structure, releasing rpDNA/HGNPs/HRP under magnetic separation. The surface plasmon resonance of HGNPs and the HRP enzyme activity of the supernatant were observed/detected with naked eyes, UV–vis spectroscopy, and electrochemistry techniques. The assay time is as short as ~45 min. CEA levels can be differentiated with naked eyes. The absorbance at 677 nm is linearly proportional to CEA concentration from 10 to 250 ng mL−1, with a limit of detection (LOD) of 8.6 ng mL−1. In contrast, the differential pulse voltammetry (DPV) peak current at -0.057 V is linearly correlated with CEA concentration in the range of 2−250 ng mL−1, with an LOD of 0.78 ng mL−1. The LOD values are lower than cancer patient threshold levels. The aptasensor exhibits negligible responses to interfering proteins. In addition, it displays good reproducibility, stability, accuracy and easiness of usage. The recovery rate for CEA spiked human serum samples are 100±5%. The developed assay strategy should provide a general platform for detecting other interested biomarkers.
- Published
- 2020
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