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60 results on '"Eccles, Diana"'

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1. Risks of second primary cancers among 584,965 female and male breast cancer survivors in England: a 25-year retrospective cohort study

3. Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants

4. Reclassification of clinically-detected sequence variants: Framework for genetic clinicians and clinical scientists by CanVIG-UK (Cancer Variant Interpretation Group UK)

5. Incorporating progesterone receptor expression into the PREDICT breast prognostic model

6. Incorporating progesterone receptor expression into the PREDICT breast prognostic model

7. Quantifying prediction of pathogenicity for within-codon concordance (PM5) using 7541 functional classifications of BRCA1 and MSH2 missense variants

8. Quantifying evidence toward pathogenicity for rare phenotypes: The case of succinate dehydrogenase genes, SDHB and SDHD

9. A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study

10. The predictive ability of the 313 variant–based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant

11. Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element

12. Harnessing national pan-laboratory data for accurate quantitation of PS4 in cancer susceptibility genes: Cancer Variant Interpretation Group UK (CanVIG-UK)

13. Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk

14. Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial

15. Interim Results from the IMPACT Study: Evidence for Prostate-specific Antigen Screening in BRCA2 Mutation Carriers

16. Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study

18. The Manchester International Consensus Group recommendations for the management of gynecological cancers in Lynch syndrome

20. Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

21. Risks of breast or ovarian cancer in BRCA1 or BRCA2 predictive test negatives: findings from the EMBRACE study

22. A Dominantly Inherited 5′ UTR Variant Causing Methylation-Associated Silencing of BRCA1 as a Cause of Breast and Ovarian Cancer

23. Circulating resistin in early-onset breast cancer patients with normal body mass index correlate with disease-free survival and lymph node involvement

24. Systematic review of the empirical investigation of resources to support decision-making regarding BRCA1 and BRCA2 genetic testing in women with breast cancer

26. No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer

27. A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies

30. Evidence of a genetic link between endometriosis and ovarian cancer

31. Effect of BRCA Mutations on Metastatic Relapse and Cause-specific Survival After Radical Treatment for Localised Prostate Cancer

32. Crowdsourcing the General Public for Large Scale Molecular Pathology Studies in Cancer

34. Evaluating the ovarian cancer gonadotropin hypothesis: A candidate gene study

35. Involvement of the SWI/SNF Complex in Familial Meningiomatosis

36. Targeted Prostate Cancer Screening in BRCA1 and BRCA2 Mutation Carriers: Results from the Initial Screening Round of the IMPACT Study

38. Long-term effect of resistant starch on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial

40. Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study

42. Increased Colorectal Cancer Incidence in Obligate Carriers of Heterozygous Mutations in MUTYH

43. Common Breast Cancer-Predisposition Alleles Are Associated with Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

48. Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH

50. MYH polyposis: A new autosomal recessive form of familial adenomatous polyposis due to defective base excision repair-reappraisal of genetic risk and family management

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