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Your search keyword '"De Massis, Patrizia"' showing total 5 results
Start Over Author "De Massis, Patrizia" Publisher elsevier bv
5 results on '"De Massis, Patrizia"'

1. Identifying and predicting amyotrophic lateral sclerosis clinical subgroups: a population-based machine-learning study

Author

Faghri, Faraz, primary, Brunn, Fabian, additional, Dadu, Anant, additional, Zucchi, Elisabetta, additional, Martinelli, Ilaria, additional, Mazzini, Letizia, additional, Vasta, Rosario, additional, Canosa, Antonio, additional, Moglia, Cristina, additional, Calvo, Andrea, additional, Nalls, Michael A, additional, Campbell, Roy H, additional, Mandrioli, Jessica, additional, Traynor, Bryan J, additional, Chiò, Adriano, additional, Manera, Umberto, additional, Palumbo, Francesca, additional, Bombaci, Alessandro, additional, Grassano, Maurizio, additional, Brunetti, Maura, additional, Casale, Federico, additional, Fuda, Giuseppe, additional, Salamone, Paolina, additional, Iazzolino, Barbara, additional, Peotta, Laura, additional, Cugnasco, Paolo, additional, De Marco, Giovanni, additional, Torrieri, Maria Claudia, additional, Gallone, Salvatore, additional, Barberis, Marco, additional, Sbaiz, Luca, additional, Gentile, Salvatore, additional, Mauro, Alessandro, additional, De Marchi, Fabiola, additional, Corrado, Lucia, additional, D'Alfonso, Sandra, additional, Bertolotto, Antonio, additional, Imperiale, Daniele, additional, De Mattei, Marco, additional, Amarù, Salvatore, additional, Comi, Cristoforo, additional, Labate, Carmelo, additional, Poglio, Fabio, additional, Ruiz, Luigi, additional, Testa, Lucia, additional, Rota, Eugenia, additional, Ghiglione, Paolo, additional, Launaro, Nicola, additional, Di Sapio, Alessia, additional, Fini, Nicola, additional, Gianferrari, Giulia, additional, Simonini, Cecilia, additional, Meletti, Stefano, additional, Liguori, Rocco, additional, Vacchiano, Veria, additional, Salvi, Fabrizio, additional, Bartolomei, Ilaria, additional, Michelucci, Roberto, additional, Cortelli, Pietro, additional, Rinaldi, Rita, additional, Borghi, Anna Maria, additional, Zini, Andrea, additional, Sette, Elisabetta, additional, Tugnoli, Valeria, additional, Pugliatti, Maura, additional, Canali, Elena, additional, Codeluppi, Luca, additional, Valzania, Franco, additional, Zinno, Lucia, additional, Pavesi, Giovanni, additional, Medici, Doriana, additional, Pilurzi, Giovanna, additional, Terlizzi, Emilio, additional, Guidetti, Donata, additional, De Pasqua, Silvia, additional, Santangelo, Mario, additional, De Massis, Patrizia, additional, Bracaglia, Martina, additional, Casmiro, Mario, additional, Querzani, Pietro, additional, Morresi, Simonetta, additional, Longoni, Marco, additional, Patuelli, Alberto, additional, Malagù, Susanna, additional, Currò Dossi, Marco, additional, Vidale, Simone, additional, and Ferro, Salvatore, additional

Published
2022
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2. A geroscience approach for Parkinson’s disease: Conceptual framework and design of PROPAG-AGEING project

Author

Pirazzini, Chiara, primary, Azevedo, Tiago, additional, Baldelli, Luca, additional, Bartoletti-Stella, Anna, additional, Calandra-Buonaura, Giovanna, additional, Dal Molin, Alessandra, additional, Dimitri, Giovanna Maria, additional, Doykov, Ivan, additional, Gómez-Garre, Pilar, additional, Hägg, Sara, additional, Hällqvist, Jenny, additional, Halsband, Claire, additional, Heywood, Wendy, additional, Jesús, Silvia, additional, Jylhävä, Juulia, additional, Kwiatkowska, Katarzyna Malgorzata, additional, Labrador-Espinosa, Miguel A., additional, Licari, Cristina, additional, Maturo, Maria Giovanna, additional, Mengozzi, Giacomo, additional, Meoni, Gaia, additional, Milazzo, Maddalena, additional, Periñán-Tocino, Maria Teresa, additional, Ravaioli, Francesco, additional, Sala, Claudia, additional, Sambati, Luisa, additional, Schade, Sebastian, additional, Schreglmann, Sebastian, additional, Spasov, Simeon, additional, Tenori, Leonardo, additional, Williams, Dylan, additional, Xumerle, Luciano, additional, Zago, Elisa, additional, Bhatia, Kailash P., additional, Capellari, Sabina, additional, Cortelli, Pietro, additional, Garagnani, Paolo, additional, Houlden, Henry, additional, Liò, Pietro, additional, Luchinat, Claudio, additional, Delledonne, Massimo, additional, Mills, Kevin, additional, Mir, Pablo, additional, Mollenhauer, Brit, additional, Nardini, Christine, additional, Pedersen, Nancy L., additional, Provini, Federica, additional, Strom, Stephen, additional, Trenkwalder, Claudia, additional, Turano, Paola, additional, Bacalini, Maria Giulia, additional, Franceschi, Claudio, additional, Adarmes-Gómez, Astrid, additional, Bonilla-Toribio, Marta, additional, Boninsegna, Claudia, additional, Broli, Marcella, additional, Buiza-Rueda, Dolores, additional, Carrión-Claro, Mario, additional, Cilea, Rosalia, additional, Clayton, Robert, additional, Molin, Alessandra Dal, additional, De Luca, Silvia, additional, De Massis, Patrizia, additional, Escuela-Martin, Rocio, additional, Fabbri, Giovanni, additional, Gabellini, Anna, additional, Giuliani, Cristina, additional, Guaraldi, Pietro, additional, Huertas, Ismae, additional, Macias, Daniel, additional, Macrì, Stefania, additional, Magrinelli, Francesca, additional, Rodríguez, Juan Francisco Martín, additional, Mignani, Francesco, additional, Nassetti, Stefania Alessandra, additional, Pirazzini, Chiara, additional, Scaglione, Cesa Lorella Maria, additional, Tejera-Parrado, Cristina, additional, Valzania, Franco, additional, and Ortega, Rosario Vigo, additional

Published
2021
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3. Clinical pharmacokinetics of pramipexole, ropinirole and rotigotine in patients with Parkinson's disease

Author

Contin, Manuela, primary, Lopane, Giovanna, additional, Mohamed, Susan, additional, Calandra-Buonaura, Giovanna, additional, Capellari, Sabina, additional, De Massis, Patrizia, additional, Nassetti, Stefania, additional, Perrone, Alessandro, additional, Riva, Roberto, additional, Sambati, Luisa, additional, Scaglione, Cesa, additional, and Cortelli, Pietro, additional

Published
2019
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4. Accuracy of MR markers for differentiating Progressive Supranuclear Palsy from Parkinson's disease

Author

Zanigni, Stefano, primary, Calandra-Buonaura, Giovanna, additional, Manners, David Neil, additional, Testa, Claudia, additional, Gibertoni, Dino, additional, Evangelisti, Stefania, additional, Sambati, Luisa, additional, Guarino, Maria, additional, De Massis, Patrizia, additional, Gramegna, Laura Ludovica, additional, Bianchini, Claudio, additional, Rucci, Paola, additional, Cortelli, Pietro, additional, Lodi, Raffaele, additional, and Tonon, Caterina, additional

Published
2016
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5. Clinical pharmacokinetics of pramipexole, ropinirole and rotigotine in patients with Parkinson's disease

Author

Giovanna Calandra-Buonaura, Alessandro Perrone, Manuela Contin, Roberto Riva, Sabina Capellari, Giovanna Lopane, Stefania Nassetti, Susan Mohamed, Luisa Sambati, Cesa Scaglione, Patrizia De Massis, Pietro Cortelli, Contin, Manuela, Lopane, Giovanna, Mohamed, Susan, Calandra-Buonaura, Giovanna, Capellari, Sabina, De Massis, Patrizia, Nassetti, Stefania, Perrone, Alessandro, Riva, Roberto, Sambati, Luisa, Scaglione, Cesa, and Cortelli, Pietro

Subjects
Adult, Male, 0301 basic medicine, medicine.medical_specialty, Indoles, Parkinson's disease, Tetrahydronaphthalenes, Clinical pharmacokinetic, Urology, Thiophenes, Single Center, 03 medical and health sciences, Pramipexole, Sex Factors, 0302 clinical medicine, Pharmacokinetics, medicine, Humans, In patient, Aged, Morning, Dopaminergic agonist, Aged, 80 and over, business.industry, Age Factors, Parkinson Disease, Rotigotine, Middle Aged, medicine.disease, 030104 developmental biology, Ropinirole, Neurology, Delayed-Action Preparations, Dopamine Agonists, Female, Neurology (clinical), Geriatrics and Gerontology, business, 030217 neurology & neurosurgery, medicine.drug
Abstract

Introduction: Pramipexole (PRA), ropinirole (ROP) and rotigotine (ROT) are non-ergoline dopaminergic agonists (DAs) used to treat Parkinson's disease (PD). Clinical pharmacokinetics of DAs is poorly characterized in PD. The main purpose of our study was to investigate the effect of dose, age and sex on steady-state plasma concentrations of DAs in real life PD patients on chronic DAs therapy. Methods: The study was single center, open and prospective. Blood samples for measurement of DAs plasma concentrations were drawn in the morning, at a median 18-h distance from the last DA dose. Results: Ninety-one patients treated with PRA, 50 with ROP and 37 with ROT were enrolled in the study. Plasma concentration of DAs significantly correlated with weight-adjusted daily dose in all subgroups, although at a given dose, matched plasma concentrations highly varied among patients. Median PRA plasma concentration-to-daily dose ratio (C/D) [(ng/mL)/(mg/kg/d)] was 68% higher in patients >65 years than ≤65 years (158 vs 94, p < 0.001), while was not affected by age in ROP and ROT subgroups. No sex-mediated differences in C/D ratios were observed in any group. Conclusion: These are the first observations on DAs pharmacokinetics in PD patients’ everyday clinical practice. Of relevance, patients over 65yrs may require about one third of PRA dose compared to under 65yrs to achieve the same plasma concentration. Due to the high intersubject variability in plasma concentrations at the same dosage, we speculate that monitoring of plasma DAs might be helpful in the individualization of treatment in selected patients.

Published
2019
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