30 results on '"Damiano, Bruce"'
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2. Combining Video Microscopy Motion Analysis and Detection of Cardiac Injury Biomarkers to Evaluate Chronic Cardiotoxicity in hiPS Cardiomyocytes
3. Can late sodium current inhibition attenuate QT prolonging effects caused by hERG blockers in in silico models
4. A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm
5. The source of hERG IC50 values (manual vs. automated patch clamp) may influence in silico modeling
6. A comparison of in silico cardiac action potential simulations with electrophysiological effects in the isolated rabbit wedge preparation for compounds with different ion channel blocking profiles
7. Characterization of an anesthetized dog model of transient cardiac ischemia and rapid pacing: A pilot study for preclinical assessment of the potential for proarrhythmic risk of novel drug candidates
8. Characterization of an anesthetized dog model of simulated angina for detection of drug-induced conduction slowing and ventricular proarrhythmia
9. A novel fluorogenic substrate for the measurement of endothelial lipase activity
10. Pharmacological characterization of RWJ-676070, a dual vasopressin V1A/V2 receptor antagonist
11. Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motif
12. Phenylpiperidine-benzoxazinones as urotensin-II receptor antagonists: Synthesis, SAR, and in vivo assessment
13. Next-generation spirobenzazepines: Identification of RWJ-676070 as a balanced vasopressin V1a/V2 receptor antagonist for human clinical studies
14. Novel bis(indolyl)maleimide pyridinophanes that are potent, selective inhibitors of glycogen synthase kinase-3
15. Selection of a 2-azabicyclo[2.2.2]octane-based α4β1 integrin antagonist as an inhaled anti-asthmatic agent
16. Aza-bicyclic amino acid carboxamides as α4β1/α4β7 integrin receptor antagonists
17. A Novel, Potent Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase
18. Characterization of functional urotensin II receptors in human skeletal muscle myoblasts: comparison with angiotensin II receptors
19. 1,2,3,4-Tetrahydroquinoline-containing αVβ3 integrin antagonists with enhanced oral bioavailability
20. Piperidine-containing β-arylpropionic acids as potent antagonists of αvβ3/αvβ5 integrins
21. 3-(7-Azaindolyl)-4-arylmaleimides as potent, selective inhibitors of glycogen synthase kinase-3
22. Corrigendum to “Aza-bicyclic amino acid sulfonamides as α4β1/α4β7 integrin antagonists”
23. Aza-bicyclic amino acid sulfonamides as α4β1/α4β7 integrin antagonists
24. Antiplatelet and Antithrombotic Activity of RWJ-53308, A Novel Orally Active Glycoprotein IIb/IIIa Antagonist
25. 1,2,4-Triazolo[3,4-a]pyridine as a novel, constrained template for fibrinogen receptor (GPIIb/IIIa) antagonists
26. Solid-phase parallel synthesis applied to lead optimization: Discovery of potent analogues of the GPIIb/IIIa antagonist RWJ-50042
27. Pharmacology of bepridil
28. Sustained electrical stimulation of the perforant path duplicates kainate-induced electrophysiological effects and hippocampal damage in rats
29. Electrophysiologic effects of AHR 10718 on isolated cardiac tissues
30. Hippocampal mediation of shaking behavior induced by electrical stimulation of the perforant path in the rat
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