1. Quantitative foetal fibronectin as a predictor of successful induction of labour in post-date pregnancies
- Author
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Dale Ojutiku, Griff Jones, and Susan Bewley
- Subjects
Adult ,medicine.medical_specialty ,Adolescent ,Vasodilator Agents ,Latent phase ,Bishop score ,Fetus ,Obstetrics and gynaecology ,Predictive Value of Tests ,Pregnancy ,medicine ,Humans ,Pregnancy, Prolonged ,Labor, Induced ,Alprostadil ,Gynecology ,Post Term Pregnancy ,biology ,Induced labour ,Obstetrics ,business.industry ,Obstetrics and Gynecology ,Fibronectins ,Fibronectin ,Reproductive Medicine ,biology.protein ,Female ,business ,Foetal fibronectin - Abstract
Objective : To study the relationship between induced labour, quantitative levels of fibronectin and the Bishop score. Study design : Vaginal fibronectin/Bishop score were estimated in 33 nulliparous women undergoing induction of labour for post-dates at the Department of Obstetrics and Gynaecology, Guy’s and St. Thomas’ Hospital London. Results : There was no significant relationship between either the fibronectin level or Bishop score and the duration of the latent phase ( R 2 =0.001; P =0.86 and R 2 =0.12; P =0.08, respectively). There was no relationship between the total prostaglandin dose and fibronectin level ( R 2 =0.03; P =0.39) nor any significant correlation between either the Bishop score or fibronectin level and the induction to delivery time ( R 2 =0.13; P =0.11 and R 2 =0.0006; P =0.97, respectively). Significant relationships were observed inversely between the total prostin dose and Bishop score ( R 2 =0.33; P =0.002), between the total prostin dose and latent phase ( R 2 =0.54; P =0.000009) and between Bishop score and the fibronectin levels ( R 2 =0.19; P Conclusions : Quantitative foetal fibronectin is not a useful test for inducibility at term.
- Published
- 2002
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