862 results on '"Coffee"'
Search Results
2. Anti-smudge and self-cleaning characteristics of waterborne polyurethane coating and its construction
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Haihang Luo, Huan Wei, Li Wang, Qiang Gao, Yi Chen, Jun Xiang, and Haojun Fan
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Biomaterials ,Colloid and Surface Chemistry ,Polyurethanes ,Water ,Dimethylpolysiloxanes ,Coffee ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials - Abstract
A novel anti-smudge coating, based on waterborne polyurethane (WPU), Polydimethylsiloxane (PDMS) and Hexamethoxymethylmelamine (HMMM) was constructed. Specifically, hydroxyl capped WPU emulsions grafted with PDMS (WPU-g-PDMS
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- 2022
3. Foods, nutrients and hip fracture risk: A prospective study of middle-aged women
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James Webster, Darren C. Greenwood, and Janet E. Cade
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Adult ,Nutrition and Dietetics ,Tea ,Hip Fractures ,Nutrients ,Middle Aged ,Critical Care and Intensive Care Medicine ,Coffee ,Cohort Studies ,Thinness ,Humans ,Female ,Prospective Studies ,Dietary Proteins ,Aged - Abstract
Hip fracture affects 1.6 million people globally each year, and increases morbidity and mortality. There is potential for risk reduction through diet modification, but prospective evidence for associations between intake of several foods and nutrients and hip fracture risk is limited. This study aimed to investigate associations between food and nutrient intakes and hip fracture risk in the UK Women's Cohort Study, and to determine the role of body mass index (BMI) as a potential effect modifier.Dietary, lifestyle, anthropometric, and socio-economic information of UK women, ages 35-69 years, were collected in a survey at recruitment (1995-1998), and included a validated 217-item food frequency questionnaire. Hip fracture cases were identified by linking participant data at recruitment with their Hospital Episode Statistics (HES) up to March 2019. Cox regression models were used to estimate associations between standard portions of food and nutrient intakes and hip fracture risk over a median follow-up time of 22.3 years.Among 26,318 women linked to HES data (556,331 person-years), 822 hip fracture cases were identified. After adjustment for confounders, every additional cup of tea or coffee per day was associated with a 4% lower risk of hip fracture (HR (95% CI): 0.96 (0.92, 1.00)). A 25 g/day increment of dietary protein intake was also associated with a 14% lower risk of hip fracture (0.86 (0.73, 1.00)). In subgroup analyses, BMI modified linear associations between dietary intakes of protein, calcium, total dairy, milk, and tea and hip fracture risk (pThis is the first prospective cohort study internationally of multiple food and nutrient intakes in relation to hip fracture risk by BMI using linkage to hospital records. Results suggest that the potential roles of some foods and nutrients in hip fracture prevention, particularly protein, tea and coffee in underweight women, merit confirmation.Clinicaltrials.gov NCT05081466.
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- 2022
4. Dietary exposure to acrylamide and breast cancer risk: results from the NutriNet-Santé cohort
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Alice Bellicha, Gaëlle Wendeu-Foyet, Xavier Coumoul, Meriem Koual, Fabrice Pierre, Françoise Guéraud, Laurent Zelek, Charlotte Debras, Bernard Srour, Laury Sellem, Emmanuelle Kesse-Guyot, Chantal Julia, Pilar Galan, Serge Hercberg, Mélanie Deschasaux-Tanguy, and Mathilde Touvier
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Acrylamide ,Nutrition and Dietetics ,Medicine (miscellaneous) ,Breast Neoplasms ,Coffee ,Hormones ,Diet ,Cohort Studies ,Dietary Exposure ,Receptors, Estrogen ,Risk Factors ,Carcinogens ,Humans ,Female ,Prospective Studies - Abstract
Acrylamide is classified as a probable human carcinogen by the International Agency for Research on Cancer but epidemiologic evidence on the carcinogenicity of acrylamide from dietary sources is limited.This study aimed to investigate the associations between dietary acrylamide and breast cancer risk in the NutriNet-Santé cohort, accounting for menopausal and hormone receptor status.This prospective cohort study included 80,597 French females (mean ± SD age at baseline: 40.8 ± 14 y) during a mean ± SD follow-up of 8.8 ± 2.3 y. Acrylamide intake was evaluated using repeated 24-h dietary records (n ± SD = 5.5 ± 3.0), linked to a comprehensive food composition database. Associations between acrylamide intake and breast cancer risk (overall, premenopausal, and postmenopausal) were assessed by Cox hazard models adjusted for known risk factors (sociodemographic, anthropometric, lifestyle, medical history, and nutritional factors).The mean ± SD dietary acrylamide intake was 30.1 ± 21.9 µg/d (main contributors: coffee, potato fries and chips, pastries, cakes, bread). During follow-up, 1016 first incident breast cancer cases were diagnosed (431 premenopausal, 585 postmenopausal). A borderline significant positive association was observed between dietary acrylamide exposure and breast cancer risk overall (HR for quartile 4 compared with 1: 1.21; 95% CI: 1.00, 1.47) and a positive association was observed with premenopausal cancer (HRQ4vs.Q1: 1.40; 95% CI: 1.04, 1.88). Restricted cubic spline analyses suggested evidence for nonlinearity of these associations, with higher HRs for intermediate (quartile 2) and high (quartile 4) exposures. Receptor-specific analyses revealed positive associations with estrogen receptor-positive breast cancer (total and premenopausal). Acrylamide intake was not associated with postmenopausal breast cancer.Results from this large prospective cohort study suggest a positive association between dietary acrylamide and breast cancer risk, especially in premenopausal females, and provide new insights that support continued mitigation strategies to reduce the content of acrylamide in food.This trial was registered at clinicaltrials.gov as NCT03335644.
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- 2022
5. Coffee and tea on cardiovascular disease (CVD) prevention
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David Chieng and Peter M. Kistler
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Adult ,Tea ,Cvd prevention ,business.industry ,Disease ,medicine.disease ,Coffee ,Lipids ,Coronary heart disease ,chemistry.chemical_compound ,chemistry ,Cardiovascular Diseases ,Risk Factors ,Caffeine ,Diabetes mellitus ,Heart failure ,Environmental health ,medicine ,Humans ,Metabolic syndrome ,Cardiology and Cardiovascular Medicine ,business ,Stroke - Abstract
Coffee and tea are amongst the most consumed beverages worldwide, and are the main source of caffeine in adults. In this review we present findings on the effects of habitual coffee and tea consumption on cardiovascular disease (CVD) prevention. Mild-moderate coffee/ caffeine consumption, at 2-3 cups/day, is associated with beneficial effects on metabolic syndrome, including hypertension and diabetes mellitus, although may elevate lipid levels. Furthermore, coffee consumption reduces the risk of coronary heart disease, heart failure, arrhythmia, stroke, CVD and all cause mortality. Higher tea consumption, in particular green tea, confers similar cardiovascular benefits to coffee with 3 cups/day associated with improved survival in population based studies.
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- 2022
6. Coffee consumption has no effect on circulating markers of liver function but increases adiponectin concentrations: A systematic review and meta-analysis of randomized controlled trials
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Enrique Linden-Torres, Graciela Zambrano-Galván, Amirhossein Sahebkar, Mayela Ríos-Mier, and Luis E. Simental-Mendía
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Alanine ,Nutrition and Dietetics ,Endocrinology, Diabetes and Metabolism ,Alanine Transaminase ,gamma-Glutamyltransferase ,Alkaline Phosphatase ,Coffee ,Endocrinology ,Liver ,Humans ,Adiponectin ,Aspartate Aminotransferases ,Lactate Dehydrogenases ,Biomarkers ,Randomized Controlled Trials as Topic - Abstract
Nonalcoholic fatty liver disease has become the most common liver disorder worldwide, reaching a prevalence of 60% and 24% in patients with chronic liver disease and the general population, respectively. Liver function is often assessed using standard liver tests such as alanine aminotransferase, aspartate aminotransferase, gamma-glutamyl transferase, and alkaline phosphatase. Randomized controlled trials (RCTs) investigating the potential beneficial effects of coffee consumption on liver function are scarce and their results are inconclusive. Some clinical trials have shown a significant increase in adiponectin concentrations following coffee consumption; however, there are few studies in this field. Hence, the hypothesis of this meta-analysis of RCTs is that coffee consumption decreases blood markers of liver function and increases adiponectin concentrations. A systematic search was conducted in PubMed-MEDLINE, Scopus, Web of Science, ClinicalTrials.gov, and Google Scholar databases. Meta-analysis was performed using a random-effects model followed by sensitivity analysis. Meta-analysis of 14 RCTs, including a total of 897 subjects, showed that coffee consumption has no significant effect on alanine aminotransferase (weighted mean difference [WMD], -0.89 mg/mL; 95% CI, -2.90 to 1.12; P = .39), aspartate aminotransferase (WMD, -0.29 mg/mL; 95% CI, -1.25 to 0.66; P = .55), gamma-glutamyl transferase (WMD, .10 mg/mL; 95% CI, -3.94 to 4.15; P = .96), alkaline phosphatase (WMD, -4.60 mg/mL; 95% CI, -9.26 to 0.07; P = .05), and lactate dehydrogenase (WMD, -0.65 mg/mL; 95% CI, -10.80 to 9.49; P = .90). However, coffee administration significantly increased adiponectin concentrations (WMD, 1.19 mg/mL; 95% CI, 0.08-2.31; P = .04). The results of this meta-analysis of RCTs suggest that coffee consumption may improve liver dysfunction through the elevation of adiponectin levels; however, further clinical trials are needed to corroborate our findings.
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- 2022
7. The rationality involved in the popular use of coffee (Coffea sp) and sunflower seed (Helianthus annuus) for the treatment of vitiligo: a case report
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Rachel Oliveira Castilho, Paula Mendonça Leite, and Stephanie D.O. Alves
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Adult ,Linoleic acid ,Vitiligo ,Coffea ,030204 cardiovascular system & hematology ,Coffee ,030207 dermatology & venereal diseases ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Chlorogenic acid ,Helianthus annuus ,medicine ,Humans ,skin and connective tissue diseases ,General Nursing ,integumentary system ,biology ,Traditional medicine ,business.industry ,medicine.disease ,biology.organism_classification ,Brosimum ,Sonchus oleraceus ,Complementary and alternative medicine ,chemistry ,Seeds ,Helianthus ,Sunflower seed ,Chiropractics ,business ,Analysis - Abstract
Introduction: Vitiligo is a dermatological disease that affects about 0.38% to 2.9% of the world population. Currently, the main treatments used for vitiligo involve the use of topical drugs such as corticosteroids and calcineurin inhibitors, phototherapy, systemic treatment with steroids and even surgical grafts and, in acute cases, depigmenting treatments. Natural products are an alternative for the treatment of vitiligo: mamacadela (Brosimum gaudichaudii), a plant rich in furanocoumarins, and sowthistle (Sonchus oleraceus), rich in phenolic substances, are already used to treat vitiligo. There are also popular reports of the use of a preparation containing coffee (Coffea sp) and sunflower seed (Helianthus annuus) to treat vitiligo. Case report: A female patient, 28 years old, diagnosed with vitiligo, reported having obtained a positive result in the repigmentation of the pale white patches after the daily use of a preparation containing coffee and sunflower seed for about one year. Discussion: Data from the scientific literature demonstrated that chemical constituents of these plants, such as chlorogenic acid and its isomers, which have antioxidant and anti-inflammatory action, and substances such as linoleic acid and vitamins E and B, which help in the process of melanin formation on the skin, may be responsible for the observed repigmentation of the patches. Further research on this case report is important for scientific validation and the development of new therapeutic options, especially with less adverse effects, in the treatment of vitiligo.
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- 2022
8. Prediagnostic plasma polyphenol concentrations and colon cancer risk: The JPHC nested case–control study
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Nagisa Mori, Neil Murphy, Norie Sawada, David Achaintre, Taiki Yamaji, Augustin Scalbert, Motoki Iwasaki, Manami Inoue, Marc J. Gunter, and Shoichiro Tsugane
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Male ,Nutrition and Dietetics ,Risk Factors ,Case-Control Studies ,Colonic Neoplasms ,Humans ,Polyphenols ,Female ,Prospective Studies ,Critical Care and Intensive Care Medicine ,Coffee - Abstract
Epidemiological studies that assessed the associations between dietary polyphenol intakes and colon cancer risk have reported largely null results, possibly due to measurement error associated with dietary assessment. We adopted an objective approach by measuring prediagnostic plasma concentrations of 35 polyphenols and assessing associations with colon cancer risk.We conducted a nested-case control study within the Japan Public Health Center-based prospective study (JPHC Study) utilizing plasma samples collected at the time of a five-year follow-up survey between 1995 and 1999. We identified colon cancer cases who developed cancer during the follow-up from the time of blood collection. Controls were matched by age, sex, area code, population size of the area, season of blood collection, year of blood collection, and duration of fasting time before the blood collection. Prediagnostic concentrations of 35 polyphenols from 375 incident colon cancer cases (followed until 2012) and 710 matched controls were measured by tandem mass spectrometry coupled with ultra-high-pressure liquid chromatography. We used multivariable conditional logistic regression models adjusted for established colon cancer risk factors to estimate odds ratios (ORs) and 95% confidence intervals (CIs).In sexes combined log2-transformed multivariable models, circulating levels of 3,4-dihydroxyphenylpropionic acid (P = 0.02), ferulic acid (P = 0.02), and caffeic acid (P = 0.03) were inversely, and 3-hydroxybenzoic acid (P = 0.03) was positively, associated with colon cancer risk. For men only, circulating levels of 3,4-dihydroxyphenylpropionic acid was inversely, and 3,5-dihydroxyphenylpropionic acid, gallic acid, (+)-epigallocatechin, 3-hydroxybenzoic acid, and epicatechin were positively, associated with colon cancer risk. In women, plasma caffeic acid and ferulic acid concentration were inversely associated with colon cancer risk. However, all these associations were nonsignificant after adjustment for multiple comparisons. The remaining polyphenols were not associated with colon cancer risk.Coffee-derived 3,4-dihydroxyphenylpropionic acid, ferulic acid, and caffeic acid concentrations were inversely associated with colon cancer risk although the association were nonsignificant after adjustment for multiple comparisons. These results support a possible role of coffee polyphenols in preventing colorectal cancer.
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- 2022
9. Ultrasounds application for nut and coffee wastes valorisation via biomolecules solubilisation and methane production
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A, Oliva, S, Papirio, G, Esposito, P N L, Lens, Oliva, Armando, Papirio, Stefano, Esposito, Giovanni, and Lens Piet, N. L.
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Polyphenol ,Biofuels ,Ultrasound ,Nuts ,Lignocellulosic material ,Anaerobiosis ,Sugars ,Coffee ,Methane ,Waste Management and Disposal - Abstract
Lignocellulosic materials (LMs) are abundant feedstocks with excellent potential for biofuels and biocommodities production. In particular, nut and coffee wastes are rich in biomolecules, e.g. sugars and polyphenols, the valorisation of which still has to be fully disclosed. This study investigated the effectiveness of ultrasounds coupled with hydrothermal (i.e. ambient temperature vs 80 °C) and methanol (MeOH)-based pretreatments for polyphenols and sugar solubilisation from hazelnut skin (HS), almond shell (AS), and spent coffee grounds (SCG). The liquid fraction obtained from the pretreated HS was the most promising in terms of biomolecules solubilisation. The highest polyphenols, i.e. 123.9 (±2.3) mg/g TS, and sugar, i.e. 146.0 (±3.4) mg/g TS, solubilisation was obtained using the MeOH-based medium. However, the MeOH-based media were not suitable for direct anaerobic digestion (AD) due to the MeOH inhibition during AD. The water-based liquors obtained from pretreated AS and SCG exhibited a higher methane potential, i.e. 434.2 (±25.1) and 685.5 (±39.5) mL CH4/g glucosein, respectively, than the HS liquors despite having a lower sugar concentration. The solid residues recovered after ultrasounds pretreatment were used as substrates for AD as well. Regardless the pretreatment condition, the methane potential of the ultrasounds pretreated HS, AS, and SCG was not improved, achieving maximally 255.4 (±7.4), 42.8 (±3.3), and 366.2 (±4.2) mL CH4/g VS, respectively. Hence, the solid and liquid fractions obtained from HS, AS, and SCG showed great potential either as substrates for AD or, in perspective, for biomolecules recovery in a biorefinery context.
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- 2022
10. The effect of reactor scale on biochars and pyrolysis liquids from slow pyrolysis of coffee silverskin, grape pomace and olive mill waste, in auger reactors
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Cristina del Pozo, Filipe Rego, Neus Puy, Jordi Bartrolí, Esteve Fàbregas, Yang Yang, and Anthony V. Bridgwater
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Charcoal ,Olea ,Vitis ,Coffee ,Waste Management and Disposal ,Pyrolysis - Abstract
Several studies have addressed the potential biorefinery, through small-scale pyrolysis, of coffee silverskin (CSS), grape pomace (GP) and olive mill waste (OMW), which are respectively the main solid residues from coffee roasting, wine making and olive oil production processes. However, increasing the scale of reactor to bring these studies to an industrial level may affect the properties, and hence applications, of the resulting products. The aim of this study is therefore to perform pilot scale experiments to compare and verify the results of analytical study (TGA) and bench scale reactor runs, in order to understand the fundamental differences and create correlations between pyrolysis runs at different scales. To this end, pyrolysis liquids and biochars from the slow pyrolysis of CSS, GP and OMW, performed using different scale auger reactors (15 kg/h and 0.3 kg/h), have been analysed (TGA, pH, density, proximate and ultimate analyses, HHV, FTIR, GCMS) and compared. The results showed no major differences in biochars when the temperature and the solid residence time were fixed. However, regarding pyrolysis liquids, compounds from the lab reactor were more degraded than pilot plant ones, due to, in this case, the vapour residence time was longer. Regarding the properties of the pyrolysis products, GP 400 °C biochars showed the best properties for combustion; CSS biochars were especially rich in nitrogen, and 400 °C GP and OMW pyrolysis liquids showed the highest number of phenolics. Hence, this study is considered a first step towards industrial scale CSS, GP and OMW pyrolysis-based biorefinery.
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- 2022
11. Coffee consumption, clinic, 24-hour and home blood pressure. Findings from the pamela study
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Fosca Quarti-Trevano, Raffaella Dell’Oro, Jennifer Vanoli, Michele Bombelli, Rita Facchetti, Giuseppe Mancia, Guido Grassi, Quarti-Trevano, F, Dell'Oro, R, Vanoli, J, Bombelli, M, Facchetti, R, Mancia, G, and Grassi, G
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Blood pressure variability ,Nutrition and Dietetics ,Endocrinology, Diabetes and Metabolism ,Heart rate ,Home blood pressure ,Clinic blood pressure ,Medicine (miscellaneous) ,Ambulatory blood pressure ,Cardiology and Cardiovascular Medicine ,Coffee - Abstract
Background and aims: Chronic coffee consuption has been reported to be associated with a modest but significant increase in blood pressure (BP), although some recent studies have shown the opposite. These data, however, largely refer to clinic BP and virtually no study evaluated cross-sectionally the association between chronic coffee consuption, out-of-office BP and BP variability. Methods and results: In 2045 subjects belonging to the population of the Pressioni Arteriose Monitorate E Loro Associazioni (PAMELA) study, we analyzed cross-sectionally the association between clinic, 24-hour, home BP and BP variability and level of chronic coffee consumption. Results show that when adjusted for confounders (age, gender, body mass index, cigarette smoking, physical activity and alcohol drinking) chronic coffee consumption does not appear to have any major lowering effect on BP values, particulary when they are assessed via 24-hour ambulatory (0 Cup/day: 118.5±0.7/72.8±0.4mmHg vs 3 cups/day: 120.2±0.4/74.8±0.3mmHg, PNS) or home BP monitoring (0 cup/day: 124.1±1.2/75.4±0.7mmHg vs 3 cups/day: 123.3±0.6/76.4±0.36mmHg, PNS). However, daytime BP was significantly higher in coffee consumers (about 2mmHg), suggesting some pressor effects of coffee which vanish during nighttime. Both BP and HR 24-hour HR variability were unaffected. Conclusion: Thus chronic coffee consumption does not appear to have any major lowering effect either on absolute BP values, particulary when they are assessed via 24-hour ambulatory or home BP monitoring, or on 24-hour BP variability.
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- 2023
12. Coffee consumption is not associated with the risk of gastric cancer: An updated systematic review and meta-analysis of prospective cohort studies
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Haizhao Song, Xinchun Shen, Qiang Chu, and Xiaodong Zheng
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Cohort Studies ,Risk ,Nutrition and Dietetics ,Endocrinology ,Risk Factors ,Stomach Neoplasms ,Endocrinology, Diabetes and Metabolism ,Humans ,Prospective Studies ,Coffee - Abstract
The results from epidemiological studies on the relationship between coffee consumption and gastric cancer risk are inconsistent and inconclusive. Based on the previous studies, we hypothesized that coffee consumption was not associated with the risk of gastric cancer. We aimed to test this hypothesis by conducting a meta-analysis to systematically review and quantify the relationship between coffee consumption and the risk of gastric cancer. Relevant prospective cohort studies were identified by a search of PubMed and Embase up to March 2021. A total of 18 independent prospective cohorts from 15 studies involving 1,608,760 participants and 3898 gastric cancer cases were included in this meta-analysis. A nonsignificant association with a pooled relative risk (RR) of 1.11 (95% confidence interval [CI], 0.99-1.25) was shown between coffee intake and the risk of gastric cancer. The dose-response analysis also suggested no significant effect on the risk of gastric cancer per 1 cup/d increment in coffee consumption (RR = 1.00; 95% CI, 0.99-1.01). No nonlinear association of gastric cancer risk with coffee consumption was found (P for nonlinearity = .17). In the subgroup analyses, significantly increased risk of gastric cancer was detected in the studies conducted in the United States (RR = 1.28; 95% CI, 1.03-1.58). In conclusion, coffee consumption had no effect on the risk of gastric cancer. However, the effect of coffee intake on persons in the United States must be further evaluated by additional high-quality and large-scale cohort studies.
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- 2022
13. Superhydrophilic three-dimensional porous spent coffee ground reduced palladium nanoparticles for efficient catalytic reduction
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Shaokai Zhang, Guangxue Chen, Minghui He, Zhaohui Yu, Junfei Tian, Huifang Chan, Xiao-Fang Wan, Congcan Shi, Zhangxiong Wu, and Shenghong Sun
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Materials science ,Water transport ,Metal Nanoparticles ,Selective catalytic reduction ,Hydrogen Peroxide ,Coffee ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Catalysis ,Nanocellulose ,Biomaterials ,Colloid and Surface Chemistry ,Chemical engineering ,Superhydrophilicity ,Water treatment ,Chemical stability ,Porosity ,Palladium - Abstract
The use of functional biodegradable wastes to treat environmental problems would create minimal extra burden to our environment. In this paper, we propose a sustainable and practical strategy to turn spent coffee ground (SCG) into a multifunctional palladium-loaded catalyst for water treatment instead of going into landfill as solid waste. Bleached delignified coffee ground (D-SCG) has a porous structure and a good capability to reduce Pd (II) to Pd (0). A large amount of nanocellulose is formed on the surface of SCG after bleaching by H2O2, which anchors and disperses the palladium nanoparticles (Pd NPs). The D-SCG loaded with Pd NPs (Pd-D-SCG) is superhydrophilic, which facilitates water transport and thus promotes efficient removal of organic pollutants dissolved in water. Pd-D-SCG exhibits excellent room temperature catalytic activity for the removal of 4-nitrophenol (4-NP) and methylene blue (MB) in water and shows good chemical stability and recyclability in water, with no obvious decrease even after five repeated cycles.
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- 2022
14. From coffee stains to uniform deposits: Significance of the contact-line mobility
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Jaka Močivnik, Barbara Malič, Aleksander Matavž, Matjaž Humar, Urša Uršič, Dmitry Richter, Simon Čopar, and Vid Bobnar
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Chemical Physics (physics.chem-ph) ,Materials science ,Drop (liquid) ,Fluid Dynamics (physics.flu-dyn) ,FOS: Physical sciences ,Physics - Fluid Dynamics ,Substrate (electronics) ,Radius ,Coffee ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Solutions ,Biomaterials ,Solvent ,Contact angle ,Colloid and Surface Chemistry ,Physics - Chemical Physics ,Phenomenological model ,Wettability ,Deposition (phase transition) ,Colloids ,Wetting ,Composite material ,Coloring Agents - Abstract
Hypothesis Contact-line motion upon drying of a sessile droplet strongly affects the solute transport and solvent evaporation profile. Hence, it should have a strong impact on the deposit formation and might be responsible for volcano-like, dome-like and flat deposit morphologies. Experiments A method based on a thin-film interference was used to track the drop height profile and contact line motion during the drying. A diverse set of drying scenarios was obtained by using inks with different solvent compositions and by adjusting the substrate wetting properties. The experimental data was compared to the predictions of a phenomenological model. Findings We highlight the essential role of contact-line mobility on the deposit morphology of solution-based inks. A pinned contact line produces exclusively ring-like deposits under normal conditions. On the contrary, drops with a mobile contact line can produce ring-, flat- or dome-like morphology. The developed phenomenological model shows that the deposit morphology depends on solvent evaporation profile, evolution of the drop radius relative to its contact angle, and the ratio between initial and maximal (gelling) solute concentration. These parameters can be adjusted by the ink solvent composition and substrate wetting behaviour, which provides a way for deposition of uniform and flat deposits via inkjet printing.
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- 2022
15. The impact of lifetime coffee and tea loads on Multiple Sclerosis severity
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Andrei Ivashynka, Maurizio A. Leone, Nadia Barizzone, Aliona Cucovici, Roberto Cantello, Domizia Vecchio, Miriam Zuccalà, Alessandro Pizzino, Massimiliano Copetti, Sandra D'Alfonso, and Andrea Fontana
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Male ,Cross-Sectional Studies ,Multiple Sclerosis ,Nutrition and Dietetics ,Tea ,Risk Factors ,Endocrinology, Diabetes and Metabolism ,Humans ,Female ,Coffee - Abstract
The association between lifestyle factors and Multiple Sclerosis (MS) disease severity and progression has been investigated to a lesser extent compared with susceptibility to the disease. We aimed to assess the impact of lifetime coffee and tea consumption on MS severity.Design: cross-sectional study. Two hundred and eight patients (139 females and 69 males) consecutively recruited at the Department of Neurology in Novara, Italy were asked about their lifetime consumption of coffee and tea. The lifetime intensity of consumption (cups/day) was estimated as the weighted sum of the mean number of standard cups drunk per day at different ages. A measure of cumulative lifetime load of the exposure was expressed in terms of cup-years. Disease severity was estimated by the Multiple Sclerosis Severity Score (MSSS). HLA-DRB1∗15 and HLA-A∗02 genotyping was performed in 167 patients.The MSSS was not associated with the status of coffee or tea consumer, or the amount of cups/day or cup-years. The Odds Ratios (OR) for falling in the upper tertile of the MSSS distribution was 1.30 (95% Confidence Interval (CI): 0.47-3.58) for coffee consumers of 1-3 cups/day and 1.14 (95%CI: 0.33-3.95) for 4-8 cups/day vs. non-consumers. The OR was 0.69 (95%CI: 0.35-1.34) for tea consumers vs. non-consumers. However, heavy consumers of coffee (4-8 cups/day) more frequently had a progressive form than small consumers (1-3 cups/day) and non-consumers (19% vs. 14% vs. 0%), and had a significantly higher age at MS onset (36.6 ± 10.3; 31.5 ± 9.5; 28.6 ± 8.1 years, p = 0.001). Although not reaching statistical significance, coffee consumers positive for HLA-A∗02 had a six-fold risk of being in the worst tertile compared to never consumers, whereas the risk was only 1.3 for coffee consumers negative for the same allele.Coffee or tea intake is not associated with different severity of MS. However, we cannot exclude a possible effect of higher doses of coffee for the subgroup of progressive patients.
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- 2022
16. Influences of spent coffee grounds on skin mucosal and serum immunities, disease resistance, and growth rate of Nile tilapia (Oreochromis niloticus) reared under biofloc system
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Sanchai Jaturasitha, Hien Van Doan, Chompunut Lumsangkul, Hung Quang Tran, Yaowaluk Chanbang, Seyed Hossein Hoseinifar, Vlastimil Stejskal, and Einar Ringø
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food.ingredient ,Aquaculture ,Aquatic Science ,Plant disease resistance ,medicine.disease_cause ,Coffee ,Fish Diseases ,Nile tilapia ,Animal science ,food ,Streptococcal Infections ,medicine ,Animals ,Environmental Chemistry ,Completely randomized design ,Disease Resistance ,biology ,business.industry ,Tilapia ,Cichlids ,General Medicine ,biology.organism_classification ,Animal Feed ,Mucus ,Diet ,Oreochromis ,Streptococcus agalactiae ,Dietary Supplements ,business - Abstract
The study was executed to find out the potential effects spent coffee ground (SCG) on Nile tilapia's skin mucosal and serum immunities, disease prevention, and growth rate reared in a biofloc system. Nile tilapia fingerlings (average weight 15.25 ± 0.07 g) were disseminated into 15 aquaria (150 L tank−1) at a density of 20 fish per aquarium and treated five diets: SCG1 (control), SCG2 (10 g kg−1), SCG3 (20 g kg−1), SCG4 (40 g kg−1), and SCG5 (80 g kg−1) for eight weeks. A Completely Randomized Design (CRD) with three replications was applied. Growth rate, skin mucus, and serum immunities were quantified every 4 weeks; whereas the challenge study was conducted at the termination of the feeding trial. The outputs indicated that dietary incorporation of SCG give rise to the enhancement of SGR and FCR in comparison with the control, with best levels noted in fish fed SCG2 diet. Similarly, significant enhancements in skin mucosal and serum immunities were revealed in fish treated SCG2 over the control and other SCG diets. Likewise, higher survival rates against Streptococcus agalactiae were displayed in fish fed SCG, with the maximum level displayed in the fish treated SCG2. In conclusion, dietary supplementation of SCG2 (10 g kg−1) can be potential used as immunostimulants in tilapia aquaculture.
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- 2022
17. An investigation of cross-sectional associations of a priori–selected dietary components with circulating bile acids
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Joshua N. Sampson, Demetrius Albanes, Rashmi Sinha, Neal D. Freedman, Erikka Loftfield, Stephanie J. Weinstein, and Doratha A. Byrd
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Dietary Fiber ,Male ,Trans fat ,Alcohol Drinking ,medicine.drug_class ,medicine.medical_treatment ,education ,Medicine (miscellaneous) ,Physiology ,Coffee ,Bile Acids and Salts ,Polyunsaturated fat ,beta-Carotene ,Linear regression ,Humans ,Medicine ,Aged ,Nutrition and Dietetics ,Cancer prevention ,Bile acid ,business.industry ,Vitamin E ,Middle Aged ,Dietary Fats ,Diet ,Original Research Communications ,Cross-Sectional Studies ,Quartile ,business - Abstract
BACKGROUND: A growing body of literature suggests chronically higher bile acid (BA) concentrations may be associated with multiple health conditions. Diet may affect BA metabolism and signaling; however, evidence from human populations is lacking. OBJECTIVES: We systematically investigated cross-sectional associations of a priori–selected dietary components (fiber, alcohol, coffee, fat) with circulating BA concentrations. METHODS: We used targeted, quantitative LC-MS/MS panels to measure 15 circulating BAs in a subset of the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study (ATBC; n = 2224) and Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO; n = 986) comprising Finnish male smokers and United States men and women, respectively. We used multivariable linear regression to estimate associations of each dietary component with log-transformed BAs; exponentiated coefficients estimate proportional differences. We included the median of the dietary component quartile in linear regression models to test for trend. RESULTS: In ATBC, fiber was inversely associated with multiple circulating BAs. The proportional difference was –10.09% (95% CI: −19.29 to 0.16; P-trend = 0.04) when comparing total BAs among those in the highest relative to the lowest fiber quartile. Alcohol, trans fat, and polyunsaturated fat were positively associated with BAs in ATBC. The proportional difference comparing total BAs among those in the highest relative to the lowest alcohol quartile was 8.76% (95% CI: –3.10 to 22.06; P-trend = 0.03). Coffee and monounsaturated fat were inversely associated with BAs. The proportional difference comparing total BAs among those in the highest relative to the lowest coffee quartile was –24.03% (95% CI: –31.57 to –15.66; P-trend
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- 2021
18. Effects of Caffeinated and Decaffeinated Coffee on Hemodialysis-Related Headache (CoffeeHD): A Randomized Multicenter Clinical Trial
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Mabel Aoun, Joseph Hajal, Najla Hilal, Dania Chelala, Celine Boueri, Ghassan Sleilaty, and Chadia Beaini
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0301 basic medicine ,medicine.medical_specialty ,medicine.medical_treatment ,030232 urology & nephrology ,Medicine (miscellaneous) ,Subgroup analysis ,Placebo ,Coffee ,Group B ,03 medical and health sciences ,0302 clinical medicine ,Double-Blind Method ,Renal Dialysis ,Caffeine ,Internal medicine ,medicine ,Humans ,Dialysis ,030109 nutrition & dietetics ,Nutrition and Dietetics ,business.industry ,Incidence (epidemiology) ,Headache ,Atrial fibrillation ,medicine.disease ,Clinical trial ,Nephrology ,Hemodialysis ,business - Abstract
Objectives Historically, headache was reported in up to 76% of hemodialysis patients. Some authors suggested that headache resulted from caffeine withdrawal. This study aims to compare the incidence of headache and hypotension between patients drinking regular or decaffeinated coffee during dialysis. Methods One-hundred fifty-six patients were enrolled in this randomized, double-blind, placebo-controlled, multicenter study. Patients with atrial fibrillation were excluded. Group A was given 80 mL of regular coffee and group B 80 mL of decaffeinated coffee (placebo) in the middle of the session for 12 consecutive sessions. Ultrafiltration rate was fixed to a maximum of 13 mL/kg/hour. The primary outcome was the incidence of headache during dialysis. Results A total of 139 patients completed the trial (6.4% vs. 15.4% of withdrawal in Groups A and B, respectively). The number of sessions with headache was not significantly different between Group A and B (33.3% vs. 37.1% respectively, P = .522), nor the number of sessions with hypotension (27% vs. 26% respectively, P = .539). In a subgroup analysis, headache tended to be more frequent in Group B (P = .06) in 2 categories of patients: those with the highest potassium dialysate (K = 2) and the non-hypertensive patients. Conclusions Headache occurred in 35% of patients during their chronic hemodialysis sessions. Caffeine intake did not prevent headache occurrence in these patients.
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- 2021
19. Habitual consumption of instant coffee is favorably associated with arterial stiffness but not with atheromatosis
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Antonios Argyris, Petros P. Sfikakis, Christiana Tsirimiagkou, Dalila Said Ouamer, Eirini D. Basdeki, Athanase D. Protogerou, Christina Chairistanidou, Kalliopi Karatzi, and Anastasia Areti Kyriazopoulou Korovesi
- Subjects
Adult ,Male ,medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,Pulse Wave Analysis ,Carotid Intima-Media Thickness ,Coffee ,Atheromatosis ,Vascular Stiffness ,Internal medicine ,medicine ,Humans ,cardiovascular diseases ,Pulse wave velocity ,Subclinical infection ,Nutrition and Dietetics ,business.industry ,Vascular disease ,Confounding ,medicine.disease ,Compliance (physiology) ,Cross-Sectional Studies ,Blood pressure ,Arterial stiffness ,Cardiology ,Female ,business - Abstract
Summary Objective Epidemiological data suggest that moderate habitual coffee consumption associates with lower cardiovascular disease (CVD) risk; however scarce data exist regarding the association of coffee with subclinical vascular disease (SVD). We aimed at investigating the above association with habitual instant coffee consumption - a widely consumed coffee in Greece–in high CVD risk but free of established CVD adults. Research methods & procedures In a cross-sectional design study we measured: (i) two 24 h dietary recalls to assess coffee consumption, (ii) arterial stiffness, by carotid to femoral pulse wave velocity - (PWV) and carotid compliance, arterial remodeling by carotid intima-media thickness (IMT), pressure wave reflection by augmentation index (AIx) and atheromatosis by carotid plaques. Results In 1041 participants (55.6% females, 53.6 ± 14.0 years), 30% habitually consumed instant coffee (0.53 ± 1.15 cups/day). Consumption of instant coffee was inversely associated with systolic blood pressure (β = −1.19, p = 0.007), AIx (β = −0.71, p = 0.043), PWV (β = −0.22, p = 0.000) and IMT (β = −0.01, p = 0.025), but these associations lost their significance after multiple adjustments for confounders. Instant coffee consumption was positively associated with carotid compliance independent from all possible confounders (β = 0.005, p = 0.003). Conclusion Habitual moderate instant coffee consumption is inversely associated with arterial stiffening and potential with arterial remodeling. These favorable vascular associations offer a potential pathophysiological link between habitual coffee consumption and lower incidence of CVD. Future studies are needed to examine the long-term effects of habitual instant coffee consumption on vascular structure and function.
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- 2021
20. Influence of dietary total antioxidant capacity on the association between smoking and hypertension in Brazilian graduates (CUME project)
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Raquel de Deus Mendonça, Josefina Bressan, Fernando Luiz Pereira de Oliveira, Aline Silva de Aguiar, Thaís da Silva Sabião, Helen Hermana Miranda Hermsdorff, Adriano Marçal Pimenta, and Júlia Cristina Cardoso Carraro
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Adult ,Male ,Endocrinology, Diabetes and Metabolism ,Population ,Medicine (miscellaneous) ,Blood Pressure ,Disease ,Logistic regression ,Coffee ,Risk Assessment ,Antioxidants ,Risk Factors ,Environmental health ,Prevalence ,Humans ,Medicine ,cardiovascular diseases ,education ,education.field_of_study ,Smokers ,Nutrition and Dietetics ,business.industry ,Smoking ,Non-Smokers ,Odds ratio ,Protective Factors ,Former Smoker ,Confidence interval ,Diet ,Cross-Sectional Studies ,Blood pressure ,Hypertension ,Cohort ,Female ,Smoking Cessation ,Ex-Smokers ,Cardiology and Cardiovascular Medicine ,business ,Nutritive Value ,Brazil - Abstract
Background and aims Hypertension (HTN) is a chronic non-communicable disease influenced by non-modifiable risk factors, such as sex and age, as well as modifiable risk factors such as lifestyle, including diet and smoking. Moreover, diet quality among smokers is worse than that of non-smokers, mainly in terms of antioxidant content. Thus, the current study aimed to investigate whether dietary total antioxidant capacity (dTAC) influences the association between smoking and HTN. Methods and results This cross-sectional study included 4303 graduates (69.35% women) from the Cohort of Minas Gerais Universities (CUME) project. An online food frequency questionnaire was administered to participants, and dTAC was estimated using the ferric reducing antioxidant power method. In the questionnaires, individuals reported smoking status, systolic and diastolic blood pressure values, previous HTN diagnosis, and use of antihypertensive drugs. Logistic regression models were used to estimate the odds ratio and 95% confidence interval between smoking and HTN, stratified by the median dTAC. Current and former smokers had higher dTAC values despite their lower fruit intake. Moreover, coffee was the main contributor to dTAC among them. Smoking was associated with a higher likelihood of HTN, mainly among individuals with a higher dTAC. However, after exclusion of coffee antioxidant capacity, there was an association between only smoking and HTN in individuals with lower dTAC. Conclusions The controversial association between higher dTAC and HTN can result from high coffee intake. Higher dTAC without coffee intake may mitigate the association between smoking and HTN in this population.
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- 2021
21. Cardiovascular symptoms affect the patterns of habitual coffee consumption
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Elina Hyppönen, Ang Zhou, Hyppönen, Elina, and Zhou, Ang
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Adult ,Male ,Tachycardia ,medicine.medical_specialty ,coffee ,Medicine (miscellaneous) ,030204 cardiovascular system & hematology ,Essential hypertension ,Coffee ,Angina ,03 medical and health sciences ,0302 clinical medicine ,Heart arrhythmia ,Risk Factors ,Internal medicine ,Heart rate ,Mendelian randomization ,heart rate ,medicine ,Palpitations ,Humans ,030212 general & internal medicine ,Aged ,Biological Specimen Banks ,decaffeinated coffee ,Nutrition and Dietetics ,business.industry ,blood pressure ,Middle Aged ,medicine.disease ,United Kingdom ,habitual coffee intake ,Blood pressure ,Cardiovascular Diseases ,Cardiology ,Female ,medicine.symptom ,business ,cardiovascular symptoms - Abstract
Background: Excessive coffee consumption can lead to unpleasant sensations such as tachycardia and heart palpitations. Objectives: Our aim was to investigate if cardiovascular symptoms can lead to alterations in habitual patterns of coffee consumption. Methods: We used information from up to 390,435 European ancestry participants in the UK Biobank, aged 39–73 y. Habitual coffee consumption was self-reported, and systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate were measured at baseline. Cardiovascular symptoms at baseline were based on hospital diagnoses, primary care records, and/or self-report. Mendelian randomization (MR) was used to examine genetic evidence for a causal association between SBP, DBP, and heart rate with habitual coffee consumption. Results: Participants with essential hypertension, angina, or heart arrhythmia were all more likely to drink less caffeinated coffee and to be non-habitual or decaffeinated coffee drinkers compared with those who did not report related symptoms (P ≤ 3.5 × 10−8 for all comparisons). Higher SBP and DBP were associated with lower caffeinated coffee consumption at baseline, with consistent genetic evidence to support a causal explanation across all methods [MR-Egger regression (MREggr) β: −0.21 cups/d (95% CI: −0.34, −0.07) per 10 mm Hg higher SBP and −0.33 (−0.61, −0.07) per 10 mm Hg higher DBP)]. In genetic analyses, higher resting heart rate was associated with a greater odds of being a decaffeinated coffee drinker (MREggr OR: 1.71; 95% CI: 1.31, 2.21) per 10 beats/min). Conclusions: We provide causal genetic evidence for cardiovascular system–driven influences on habitual coffee intakes, suggesting that people tend to naturally regulate their coffee consumption based on blood pressure levels and heart rate. These findings suggest that observational studies of habitual coffee intakes are prone to influences by reverse causation, and caution is required when inferred health benefits result from comparisons with coffee abstainers or decaffeinated coffee drinkers. Refereed/Peer-reviewed
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- 2021
22. The psychology of object attachment: Our bond with teddy bears, coffee mugs, and wedding rings
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Melissa M. Norberg and Derek D. Rucker
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Bond ,Humans ,Psychology, Child ,Psychology ,Coffee ,Object Attachment ,Crime Victims ,General Psychology ,Linguistics - Published
- 2021
23. Policy integration as a means to address policy fragmentation: Assessing the role of Vietnam’s national REDD+ action plan in the central highlands
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Maria Brockhaus, Simon R. Bush, Gabrielle Kissinger, International Forest Policy, and Department of Forest Sciences
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010504 meteorology & atmospheric sciences ,Process (engineering) ,media_common.quotation_subject ,REDD plus ,Geography, Planning and Development ,Commodity ,WASS ,010501 environmental sciences ,Management, Monitoring, Policy and Law ,Coffee ,01 natural sciences ,Policy integration ,Environmental planning ,NRAP ,0105 earth and related environmental sciences ,media_common ,4112 Forestry ,Milieubeleid ,5203 Global Development Studies ,WIMEK ,Land use ,Policy fragmentation ,15. Life on land ,Environmental Policy ,Negotiation ,Vietnam ,13. Climate action ,Scale (social sciences) ,Action plan ,Mandate ,Rubber ,Business ,5172 Global Politics ,REDD+ ,Central highlands - Abstract
The Vietnamese National REDD + Action Plan (NRAP) seeks to reduce emissions from forest clearing and land use, especially from the main drivers of coffee and rubber commodity expansion. Achieving the NRAP goals, however, means negotiating a complex and fragmented forest policy arena, with conflicting sector goals, disconnects between global and local ambition and action, and imbalanced power dynamics between actors. We map the fragmentation of this policy arena and explore the extent to which the NRAP is able to integrate policy responses to drivers to achieve emissions reductions. We examine what the NRAP sought to integrate, what was not taken into account, what is integrated at which scale, and which actors are part of integration (or not) across the policy process components. We conclude that if policy integration does not affect a ?whole of government? shift in priorities or change in mandate among driver sectors, fragmented policy arenas will persist and forest based climate mitigation objectives will not be achieved.
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- 2021
24. Coffee consumption and risk of hearing impairment in men and women
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Marcos D Machado-Fragua, Humberto Yévenes-Briones, Francisco Félix Caballero, Fernando Rodríguez-Artalejo, Ellen A Struijk, and Esther Lopez-Garcia
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Male ,0301 basic medicine ,Longitudinal study ,medicine.medical_specialty ,Hearing loss ,030209 endocrinology & metabolism ,Coffee consumption ,Audiology ,Critical Care and Intensive Care Medicine ,Lower risk ,Coffee ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,otorhinolaryngologic diseases ,medicine ,Humans ,Longitudinal Studies ,Speech reception threshold ,Hearing Loss ,030109 nutrition & dietetics ,Nutrition and Dietetics ,Proportional hazards model ,business.industry ,Middle Aged ,Diet ,Cohort ,Female ,Physical exam ,medicine.symptom ,business - Abstract
Hearing loss is the fifth leading cause of disability in the world. Coffee consumption might have a beneficial effect on hearing function because of the antioxidant and anti-inflammatory properties of some of its compounds. However, no previous longitudinal study has assessed the association between coffee consumption and the risk of hearing impairment.To assess the prospective association between coffee consumption and risk of disabling hearing impairment in middle and older men and women from the UK Biobank study.Analytical cohort with 36,923 participants (16,142 men and 20,781 women) [mean (SD): 56.6 (7.8) years, 1.6 (1.4) cups/d, and -7.6 (1.3) dB for age, total coffee consumption and speech reception threshold in noise at baseline, respectively]. At baseline, coffee consumption was measured with 3-5 multiple-pass 24-h food records. Hearing function was measured with a digit triplet test, and disabling hearing impairment was defined as a speech reception threshold in noise -3.5 dB in any physical exam during the follow-up. Analyses were stratified by sex and Cox regression models were used to assess the prospective association proposed.Over 10 years of follow-up, 343 men and 345 women developed disabling hearing impairment. Among men, compared with those who consumed1 cup/d of coffee, those who consumed 1, and ≥2 cups/d had a lower risk of hearing impairment (hazard ratio [95% confidence interval]: 0.72 [0.54-0.97] and 0.72 [0.56-0.92], respectively; P-trend: 0.01). This association was similar for caffeinated and decaffeinated coffee, and for filtered and non-filtered coffee, and was stronger in those with obesity (hazard ratio [95% confidence interval] for consumption of ≥2 vs.1 cups/d: 0.39 [0.21-0.74]). No association was found between coffee and hearing function among women.Coffee consumption was associated with lower risk of disabling hearing impairment in men but not in women. The association appeared to be independent of the coffee type and the preparation method.
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- 2021
25. Public health impact of daily life triggers of sudden cardiac death: A systematic review and comparative risk assessment
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Riccardo Proietti, Ahmed AlTurki, and Viktor Čulić
- Subjects
medicine.medical_specialty ,Physical Exertion ,Population ,030204 cardiovascular system & hematology ,Emergency Nursing ,Coffee ,Risk Assessment ,Sudden cardiac death ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,medicine ,Humans ,Exertion ,education ,education.field_of_study ,biology ,business.industry ,Public health ,030208 emergency & critical care medicine ,medicine.disease ,biology.organism_classification ,Confidence interval ,Death, Sudden, Cardiac ,Relative risk ,Emergency Medicine ,Public Health ,Cannabis ,Cardiology and Cardiovascular Medicine ,business ,Risk assessment ,Alcohol Cocaine Coffee Psycho-emotional stress Physical exertion Sudden cardiac death Trigger ,Demography - Abstract
Background Sudden cardiac death (SCD) may be triggered by daily circumstances and activities such as stressful psycho-emotional events, physical exertion or substance misuse. We calculated population attributable fractions (PAFs) to estimate the public health relevance of daily life triggers of SCD and to compare their population impacts. Methods We searched PubMed, Scopus and the Web of Science citation databases to retrieve studies of triggers of SCD and cardiac arrest that would enable a computation of PAFs. When more studies investigated the same trigger, a meta-analytical pooled risk random-effect estimate was used. Results Of the retrieved studies, eight provided data enabling computation of PAFs. The prevalence of exposure within population for SCD triggers in the control periods ranged from 1.06% for influenza infection to 8.73% for recent use of cannabis. Triggers ordered from the highest to the lowest risk increase were: physical exertion, recent cocaine use, episodic alcohol consumption, recent amphetamine use, episodic coffee consumption, psycho-emotional stress within the previous month, influenza infection, and recent cannabis use. The relative risk increase ranged from 1.10 to 4.98. By accounting for both the magnitude of the risk increase and the prevalence in the population, the present estimates of PAF assign 14.5% (95% confidence interval [CI] 4.9–28.5) of all SCDs to episodic alcohol consumption, 9.4% (95% CI 1.2–29.3) to physical exertion, 6.9% (95% CI 0.3–25.0) to cocaine, 6% (95% CI 1.2–14.6) to episodic coffee consumption, 3% (95% CI 0.4–6.8) to psycho-emotional stress in the previous month, 1.7% (95% CI −0.9 to 12.9) to amphetamines, 0.9% (95% CI −4.9 to 12.5) to cannabis, and 0.3% (95% CI 0.2–0.4) to influenza infections. Conclusions In addition to episodic alcohol consumption, a trigger with the greatest public health importance for SCD, episodic physical exertion, cocaine use and coffee consumption also show a considerable population impact.
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- 2021
26. Acute effect of coffee consumption on blood pressure, QTc interval, and heart rate variability in people with type 2 diabetes
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Ourania Zacharopoulou, Georgia Samakidou, Ioanna Eleftheriadou, Anastasios Tentolouris, Nikolaos Chatzieleftheriou, Ourania Kosta, and Nikolaos Tentolouris
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Electrocardiography ,Diabetes Mellitus, Type 2 ,Heart Rate ,Humans ,Blood Pressure ,Cardiology and Cardiovascular Medicine ,Coffee - Published
- 2022
27. An Uncommon Cause of Coffee Ground Emesis in a Young Woman With Remote Roux-en-Y Gastric Bypass
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Catherine Mezzacappa, Michelle L. Hughes, and Kenneth W. Hung
- Subjects
Hepatology ,Vomiting ,Gastric Bypass ,Gastroenterology ,Humans ,Anastomosis, Roux-en-Y ,Female ,Laparoscopy ,Coffee ,Intussusception ,Obesity, Morbid - Published
- 2022
28. Editorial commentary: Coffee, tea, and the cardiac diet
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Joshua Schulman-Marcus and Jacob P. Kolenda
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Text mining ,Tea ,business.industry ,Humans ,Medicine ,Cardiology and Cardiovascular Medicine ,business ,Coffee ,Diet ,Biotechnology - Published
- 2022
29. Tuning structure of spent coffee ground lignin by temperature fractionation to improve lignin-based carbon nanofibers mechanical performance
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Ling-Ping Xiao, Jiliang Ma, Jinghui Zhou, Xiaohong Chen, Run-Cang Sun, Hongwei Zhu, Xing Wang, and Boyu Du
- Subjects
Dispersity ,Acrylic Resins ,Nanofibers ,Mixing (process engineering) ,Industrial Waste ,02 engineering and technology ,Fractionation ,Chemical Fractionation ,Raw material ,Coffee ,Lignin ,Biochemistry ,03 medical and health sciences ,chemistry.chemical_compound ,Structural Biology ,Molecular Biology ,030304 developmental biology ,0303 health sciences ,Carbon nanofiber ,Temperature ,Polyacrylonitrile ,Substrate (chemistry) ,General Medicine ,021001 nanoscience & nanotechnology ,Carbon ,chemistry ,Chemical engineering ,0210 nano-technology - Abstract
Fabricating lignin-based carbon nanofibers (LCNFs) with the lignin in spent coffee grounds (SCG) as raw material which are disposed as waste amounting to millions tons annual is benefit to promote economy and environmental protection. However, due to the heterogeneity and complex three-dimensional structure, the mechanic property is very poor. In this study, we propose a fractionating pretreatment method to overcome the above problems by regulating the structure of SCG lignin in which high-performance LCNFs were fabricated. On one hand, the linear structure of SCG lignin was optimized to fit the raw material of LCNFs by tuning the content of β-O-4 and C5-substituted condensed phenolic compounds. On the other hand, the carboxyl as the hydrophilic groups was removed so as to promote the mixing of lignin and polyacrylonitrile (PAN, blending agent) in organic solvents. Additionally, the heterogeneity was reduced by screening large molecular weight SCG lignin with low polydispersity index (PDI). Fortunately, with 1:1 mass ratio of the above fractionated lignin and PAN as substrate, the LCNFs could reach to comparable mechanic properties with those of pure PAN CNFs. This work can provide a new way to not only promote the utilization of SCG lignin but also accelerate the development of LCNFs.
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- 2021
30. Utilization of coffee pulp waste for rapid recovery of pectin and polyphenols for sustainable material recycle
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K. A. Anu Appaiah, Aparna Padmanabhan, and Vallamkondu Manasa
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food.ingredient ,Pectin ,DPPH ,020209 energy ,02 engineering and technology ,010501 environmental sciences ,engineering.material ,Coffee ,01 natural sciences ,Antioxidants ,Ferulic acid ,chemistry.chemical_compound ,food ,0202 electrical engineering, electronic engineering, information engineering ,Food science ,Waste Management and Disposal ,Chromatography, High Pressure Liquid ,0105 earth and related environmental sciences ,ABTS ,Vanillin ,Pulp (paper) ,Polyphenols ,food and beverages ,Catechin ,chemistry ,Polyphenol ,engineering ,Pectins - Abstract
Coffee pulp is one of the major underutilized byproduct of coffee processing in farm level. Disposal of this agro-industrial waste has become one of the most challenging tasks for coffee planters. However, most of the efforts are towards the management of coffee pulp as an effluent, and not-on re-use. The problem is compounded due to the large volumes produced in diluted forms, which makes it expensive to reuse. The preliminary proximate analysis of coffee pulp indicated it to be rich in pectin and polyphenols. The efficacy of various chemicals like ethanol, sulfuric acid, hydrochloric acid, nitric acid, ammonium oxalate and metal salts for effective precipitation of pectin from coffee pulp was evaluated. HPLC characterization of the extracted and concentrated polyphenols fractions was analyzed. The maximum extraction of pectin was achieved by using metal salts and ethanol with 6.0% and 6.7% on wet weight basis respectively. The equivalent weight of extracted pectin (1180.5 mg/g) was found to be higher than that of commercial pectin (724.8 mg/g). The methoxyl content of the commercial pectin and crude pectin were 9.3 and 5.6% respectively. Gallic, vanillin, catechin, ethyl catechol, coumaric, Caffeic, and ferulic acid were the major polyphenols as quantified by the HPLC. The polyphenol fraction showed a good antioxidant activity with phosphomolybdate, FRAP, DPPH, and ABTS radicals respectively. The sustainable utilization of coffee pulp as a source of pectin and polyphenols with good antioxidant activities could help to solve the problem of waste generated in coffee processing in farm level.
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- 2021
31. Coffee consumption and risk of hypertension: A prospective analysis in the cohort study
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Paulo A. Lotufo, Dirce Maria Lobo Marchioni, Isabela M. Benseñor, Alessandra C. Goulart, and Andreia Machado Miranda
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Adult ,Male ,0301 basic medicine ,Longitudinal study ,Drinking ,030209 endocrinology & metabolism ,Critical Care and Intensive Care Medicine ,Coffee ,Diet Surveys ,03 medical and health sciences ,symbols.namesake ,0302 clinical medicine ,Humans ,Medicine ,Longitudinal Studies ,Prospective Studies ,Poisson regression ,Prospective cohort study ,Aged ,030109 nutrition & dietetics ,Nutrition and Dietetics ,business.industry ,Incidence ,Incidence (epidemiology) ,Smoking ,Feeding Behavior ,Middle Aged ,Diet ,Blood pressure ,Heart Disease Risk Factors ,Relative risk ,Hypertension ,Cohort ,symbols ,Female ,business ,Brazil ,Demography ,Cohort study - Abstract
Summary Background Coffee is one of the most widely consumed beverages around the world. Dietary habits, specifically, coffee consumption has long been a suspected cause of hypertension. However, previous findings on coffee consumption and its association with the incidence of hypertension are not homogeneous and still inconsistent. Purpose To examine the association of habitual coffee consumption with the risk of developing hypertension in a middle-aged Brazilian cohort. Methods Data were from the multicenter prospective cohort “Brazilian Longitudinal Study for Adult Health - ELSA-Brasil”. The cohort comprises 15,105 civil servants, aged 35–74 years at baseline, who were sampled from universities located in six Brazilian cities. For the present study, we analyzed data from 8780 participants initially free of hypertension during a mean follow-up of 3.9 years. The consumption of coffee was obtained at baseline using a previously validated semi-quantitative food frequency questionnaire (FFQ). Subsequently coffee intake was categorized into four categories (cups/day): never/almost never, ≤1, 1–3, and >3. Hypertension status was defined as a systolic blood pressure ≥140 mmHg or a diastolic blood pressure ≥90 mmHg, use of antihypertensive drug treatment, or both. Poisson regression model with a robust variance was performed to estimate relative risk (RR) and confidence interval (95% CI) for hypertension according to baseline coffee consumption. The effect of interaction between coffee consumption and smoking status was assessed. Results Most participants (90%) drank coffee, and the median total coffee intake was 150 mL/day. A total of 1285 participants developed hypertension. Compared to participants who never or almost never drink coffee, the risk of hypertension was lower for individuals consuming 1–3 cups/day (RR 0.82, 95% CI: 0.68-0.97) (P for interaction=0.018). After stratification by smoking status the analysis revealed a decreased risk of hypertension in never smokers drinking 1–3 cups of coffee per day (RR 0.79, 95% CI: 0.64-0.98), whereas the hypertension risk among former and current smokers was not associated with coffee consumption significantly. Moreover, upper category of coffee drinking (>3 cups/day) the association was not significant for risk of hypertension. Conclusion The association between coffee consumption and incidence of hypertension was related to smoking status. The beneficial effect of moderate coffee intake (1–3 cups/day) on risk of hypertension was observed only in never smokers.
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- 2021
32. Potential applications of by-products from the coffee industry in polymer technology – Current state and perspectives
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Aleksander Hejna
- Subjects
Antifungal ,Technology ,Polymers ,medicine.drug_class ,020209 energy ,02 engineering and technology ,010501 environmental sciences ,Coffee ,01 natural sciences ,Beverages ,Research based ,0202 electrical engineering, electronic engineering, information engineering ,Polymer composites ,medicine ,Business ,Biochemical engineering ,Coffee bean ,Waste Management and Disposal ,Oxidation resistance ,0105 earth and related environmental sciences - Abstract
Coffee is one of the most popular beverages in the world, and its popularity is continuously growing, which can be expressed by almost doubling production over the last three decades. Cultivation, processing, roasting, and brewing coffee are known for many years. These processes generate significant amounts of by-products since coffee bean stands for around 50% of the coffee cherry. Therefore, considering the current pro-ecological trends, it is essential to develop the utilization methods for the other 50% of the coffee cherry. Among the possibilities, much attention is drawn to polymer chemistry and technology. This industry branch may efficiently consume different types of lignocellulosic materials to use them as fillers for polymer composites or as intermediate sources of particular chemical compounds. Moreover, due to their chemical composition, coffee industry by-products may be used as additives modifying the oxidation resistance, antimicrobial, or antifungal properties of polymeric materials. These issues should be considered especially important in the case of biodegradable polymers, whose popularity is growing over the last years. This paper summarizes the literature reports related to the generation and composition of the coffee industry by-products, as well as the attempts of their incorporation into polymer technology. Moreover, potential directions of research based on the possibilities offered by the coffee industry by-products are presented.
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- 2021
33. Acute dose-response effect of coffee-derived chlorogenic acids on the human vasculature in healthy volunteers: a randomized controlled trial
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Nicola Galaffu, Rachid Bel Rhlid, Lucas Actis-Goretta, Antonio De Castro, Antoine Lévèques, Diane Zimmermann, Carmine D'Urzo, Daniel J. Green, Marjorie Guitard-Uldry, Louise H. Naylor, Erno Van Schaick, Laure Poquet, and Bjorn Eriksen
- Subjects
Male ,0301 basic medicine ,Endothelium ,coffee ,Medicine (miscellaneous) ,Coffea ,030204 cardiovascular system & hematology ,Pharmacology ,Placebo ,Lower risk ,AcademicSubjects/MED00160 ,AcademicSubjects/MED00060 ,03 medical and health sciences ,0302 clinical medicine ,endothelial function ,Double-Blind Method ,medicine.artery ,Hydroxybenzoates ,medicine ,Humans ,Ingestion ,flow-mediated dilation ,human ,Brachial artery ,030109 nutrition & dietetics ,Nutrition and Dietetics ,Dose-Response Relationship, Drug ,business.industry ,Middle Aged ,Crossover study ,Vasodilation ,Original Research Communications ,medicine.anatomical_structure ,Blood pressure ,Green coffee extract ,Female ,Chlorogenic Acid ,phenolic acids ,business - Abstract
Background Epidemiological studies have reported lower risk of cardiovascular disease with moderate coffee consumption. In addition, emerging evidence indicates that consumption of coffee beverages enriched in chlorogenic acids (CGAs) may influence blood pressure and endothelial function, suggesting that the beneficial cardiovascular effect of coffee may relate to its CGA content. Objectives We conducted a double-blind randomized crossover trial to test the effect of acute consumption of a decaffeinated green coffee extract (DGCE), rich in CGAs, on endothelial function in healthy subjects. Methods We compared 3 different doses of DGCE (302, 604, and 906 mg, respectively) with a placebo. Endothelial function was defined as the percentage change in the internal diameter of the brachial artery in response to flow-mediated dilation (%FMD). In addition, we followed the plasma concentration-time profiles of 25 systemic CGA metabolites over 24 h after DGCE consumption and we explored the relation between systemic concentrations of CGAs and the effect on %FMD. Results The DGCE formulations containing different amounts of CGAs resulted in dose-proportional increases in overall total polyphenol concentrations. The systemic appearance of total CGAs was biphasic, in agreement with previous results suggesting 2 sites of absorption in the gastrointestinal tract. Compared with the placebo group, a significant FMD increase (>1%) was observed 8.5, 10, and 24 h after consumption of 302 mg DGCE (∼156.4 mg CGAs). The differences with placebo observed in the other 2 groups were not statistically significant. Evaluation of the relation between phenolic exposure and %FMD showed a positive tendency toward a larger effect at higher concentrations and different behavior of CGA metabolites depending on the conjugated chemical position. Conclusions We demonstrated an acute improvement in %FMD over time after ingestion of a DGCE, explained at least partly by the presence in the blood circulation of CGAs and their metabolites. This trial was registered at clinicaltrials.gov as NCT03520452.
- Published
- 2021
34. Coffee consumption and mortality in Japan with 18 years of follow-up: the Jichi Medical School Cohort Study
- Author
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N. Nakaya, Toyohiro Hamaguchi, Kazunori Kayaba, Kazuhiko Kotani, Shizukiyo Ishikawa, T. Sakamaki, and M. Namekawa
- Subjects
Adult ,Male ,Coronary Disease ,Coffee consumption ,Coffee ,Cohort Studies ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Japan ,Cause of Death ,Neoplasms ,Surveys and Questionnaires ,medicine ,Humans ,Prospective Studies ,030212 general & internal medicine ,Prospective cohort study ,Stroke ,Schools, Medical ,Aged ,Proportional Hazards Models ,Aged, 80 and over ,Proportional hazards model ,business.industry ,030503 health policy & services ,Hazard ratio ,Public Health, Environmental and Occupational Health ,Cancer ,General Medicine ,Middle Aged ,medicine.disease ,Confidence interval ,Female ,0305 other medical science ,business ,Demography ,Cohort study - Abstract
Objective Coffee consumption can be expected to reduce mortality due to cardiovascular diseases and cancer. This study tested the hypothesis of an inverse association between coffee intake and all-cause mortality and mortality due to cancer, coronary heart disease, or stroke. Study design Prospective cohort study. Methods We analyzed data from the Jichi Medical School Cohort Study, Japan, enrolling 9946 subjects (men/women: 3870/6,076, age: 19–93 years) from 12 communities. A food frequency questionnaire assessing the subjects’ daily coffee consumption was used. Results During an average follow-up of 18.4 years, the total number of deaths was 2024, including 677 for cancer, 238 for coronary heart disease, and 244 for stroke. Cox proportional hazards models were used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) of all-cause mortality and cause-specific mortality due to cancer, coronary heart disease, and stroke. Overall, no significant association was shown between coffee consumption and all-cause mortality. In the cause-specific mortality analyses, stroke mortality was significantly lower in those who consumed 1–2 cups of coffee daily (HR [95% CI]: 0.63 [0.42–0.95]) than in those who do not consume coffee, and this association occurred only in men. Conclusion This study showed no significant association between coffee consumption and all-cause mortality. A U-shaped association between coffee consumption and stroke mortality with a 37% lower stroke mortality, only significant in men who consume 1–2 cups of coffee daily was observed. It is necessary to examine the possibility of intervention studies to reduce stroke mortality through coffee consumption
- Published
- 2021
35. Anabolism of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) by Cupriavidus necator DSM 545 from spent coffee grounds oil
- Author
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Haydn Rhys Ingram and James Winterburn
- Subjects
0106 biological sciences ,food.ingredient ,Anabolism ,Polyesters ,Cupriavidus necator ,Biomass ,Bioengineering ,Coffee ,01 natural sciences ,03 medical and health sciences ,chemistry.chemical_compound ,food ,010608 biotechnology ,Bioreactor ,Succinyl-CoA ,Food science ,Molecular Biology ,030304 developmental biology ,chemistry.chemical_classification ,0303 health sciences ,Molecular Structure ,biology ,Sunflower oil ,General Medicine ,Tricarboxylic acid ,biology.organism_classification ,Metabolic pathway ,chemistry ,Oils ,Biotechnology - Abstract
Oil extracted from spent coffee grounds (SCG) [yield 16.8 % (w/w)] was discovered to be a highly suitable carbon substrate for the biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) [P(3HB-co-3 HV)] copolymers by Cupriavidus necator DSM 545 in the absence of any traditional 3 HV precursors. Cells cultivated in a 3 L bioreactor (batch) reached a total biomass concentration of 8.9 g L−1 with a P(3HB-co-3 HV) (6.8 mol% 3 HV) content of 89.6 % (w/w). In contrast, cells grown on sunflower oil reached a total biomass concentration of 9.4 gL−1 with a P(3HB-co-3 HV) (0.2 mol% 3 HV) content of 88.1 % (w/w). It is proposed that the organism could synthesize 3 HV monomers from succinyl CoA, an intermediate of the tricarboxylic acid (TCA) cycle, via the succinate-propionate metabolic pathway.
- Published
- 2021
36. Estrogenic activity of capsule coffee using the VM7Luc4E2 assay
- Author
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Melissa M. Melough, Junichi R Sakaki, Christopher Perkins, Anthony A. Provatas, Cathy Z. Yang, and Ock K. Chun
- Subjects
DBP, dibutyl phthalate ,Bisphenol A ,EEF, estradiol equivalent factor ,Dibutyl phthalate ,medicine.drug_class ,bisphenol A ,Health, Toxicology and Mutagenesis ,Estrogen receptor ,Estrogenic activity ,Plastic ,Toxicology ,Tandem mass spectrometry ,Coffee ,Applied Microbiology and Biotechnology ,Article ,chemistry.chemical_compound ,EEQ, estradiol equivalent concentration ,4-NP, 4-nonylphenol ,RA1190-1270 ,medicine ,BPS, bisphenol S ,Food science ,Capsule ,ComputingMethodologies_COMPUTERGRAPHICS ,RLU, relative luminescence units ,RME2, relative maximum amplitude response of E2 ,UPLC-MS/MS, ultra-performance liquid chromatography with tandem mass spectrometry ,Estrogen ,Orders of magnitude (mass) ,In vitro ,BP, benzophenone ,BPA, bisphenol A ,chemistry ,HPLC, high-performance liquid chromatography ,Toxicology. Poisons ,E2, 17β-estradiol ,hormones, hormone substitutes, and hormone antagonists ,BPF, bisphenol F - Abstract
Graphical abstract, Highlights • Capsule coffee samples were positive for estrogenic activity in VM7Luc4E2 assay. • Estrogenic potential of coffee was 107 times weaker than that of 17β-estradiol. • Estrogenic chemical contamination is likely driver of estrogenic potential., Coffee brewed from capsule machines may contain estrogenic chemicals migrated from plastic, but the estrogenic activity of capsule coffee has not been evaluated. This study evaluated the estrogenic activity of capsule coffee using the VM7Luc4E2 estrogen receptor transcriptional activation assay. Estrogenic potentials of six capsule coffee samples were calculated using relative maximum amplitude response of E2 (>15%RME2 indicative of estrogenic activity) and estradiol equivalent factor (EEF). Estrogenic chemical content was determined using ultra-performance liquid chromatography with tandem mass spectrometry. All capsule coffee samples possessed estrogenic activity (48–56%RME2). EEFs were 6–7 orders of magnitude lower than that of E2, (1.2 × 10−7−1.7 × 10−6), indicating substantially weaker estrogenic potencies. Bisphenol A, bisphenol F, benzophenone, 4-nonylphenol, dibutyl phthalate, and dimethyl terephthalate were detected in capsule coffee. Capsule coffee exhibited estrogenic activity in vitro, and its estrogenic chemical content is likely driving its estrogenicity, warranting further investigations to fully understand the degree to which they are related and to predict the estrogenic potential based on the concentration of estrogenic chemicals.
- Published
- 2021
37. Indoleamine 2,3 dioxygenase 1 immobilization on magnetic nanoparticles for screening inhibitors from coffee
- Author
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Liu, Zhuoting, Ping, Yunfang, Zhang, Lumei, Zhang, Jingran, Van Schepdael, Ann, and Wang, Xu
- Subjects
Neochlorogenic acid (PubChem CID 5280633) ,Ferulic acid (PubChem CID 445858) ,Ligand fishing ,Cryptochlorogenic acid (PubChem CID 9798666) ,Coffee ,Analytical Chemistry ,Chlorogenic acid (PubChem CID 1794427) ,5-O-feruloylquinic acid (PubChem CID 73210496) ,Caffeine (PubChem CID 2519) ,Immobilized IDO1 ,Isochlorogenic acid B (PubChem CID 5281780) ,Magnetic nanoparticles ,Molecular docking ,3-O-feruloylquinic acid (PubChem CID 9799386) ,Isochlorogenic acid A (PubChem CID 6474310) ,Isochlorogenic acid C (PubChem CID 6474309) ,Food Science - Abstract
In this study, a ligand fishing method was developed to screen potential indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors from coffee extracts by immobilization of IDO1 enzyme on amino-modified magnetic nanoparticles combined with UHPLC-Q-TOF-MS/MS analysis. Parameters including enzyme concentration, immobilization time, the pH of glutaraldehyde and the amount of magnetic nanoparticles were optimized. The results indicated that immobilized IDO1 could be reused 5 times and was stable during storage for 7 days. Several IDO1 ligands were captured by incubating immobilized IDO1 with coffee extract, of which 10 showed an obvious difference comparing to non-conjugated bare nanoparticles. In vitro inhibitory activity was further performed by CE analysis, in which ferulic acid and chlorogenic acid had better IDO1 inhibitory activity, with IC50 value of 113.7 μM and 307.5 μM. These results demonstrate that this method provides an effective platform for identifying and screening IDO1 inhibitors from natural products. ispartof: FOOD CHEMISTRY-X vol:17 ispartof: location:Netherlands status: published
- Published
- 2023
38. Metabolites of dietary atractyligenin glucoside in coffee drinkers' urine
- Author
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Roman Lang, Anja Beusch, and Sebastian Dirndorfer
- Subjects
Glucuronides ,Glucosides ,Humans ,Coffea ,General Medicine ,Atractyloside ,Coffee ,Food Science ,Analytical Chemistry - Abstract
Arabica roast coffee contains a substantial amount of water soluble atractyligenin-2-O-β-d-glucoside, which is ingested by consumption of coffee brew. Metabolomics data suggest this coffee compound is excreted as glucuronides, but the structures of conjugates have not been elucidated so far. We collected coffee drinkers' urine and isolated four metabolites by MS-guided liquid chromatographic fractionation. The structures were investigated by nuclear magnetic resonance (NMR) and time-of-flight mass spectrometry (ToF-MS) and identified as atractyligenin-19-O-β-d-glucuronide (M1), 2β-hydroxy-15-oxoatractylan-4α-carboxy-19-O-β-d-glucuronide (M2), and 2β-hydroxy-15-oxoatractylan-4α-carboxylic acid-2-O-β-d-glucuronide (M3). An unconjugated metabolite (M4) was confirmed as atractyligenin. We analyzed spot urines from n = 6 coffee drinking individuals and detected the metabolites M1, M2 and M4 in every sample, and M3 in four out of six samples, suggesting interindividual differences in metabolism.
- Published
- 2023
39. Inoculation of yeast and bacterium in wet-processed Coffea canephora
- Author
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Danielle Gonçalves Bravim, Taynara Mota de Oliveira, Denes Kaic Alves do Rosário, Nádia Nara Batista, Rosane Freitas Schwan, Jussara Moreira Coelho, and Patricia Campos Bernardes
- Subjects
Glucose ,Bacteria ,Lactobacillales ,Yeasts ,Coffea ,Fructose ,General Medicine ,Coffee ,Heptanol ,Food Science ,Analytical Chemistry - Abstract
This study evaluated the inoculation of Meyerozyma guilliermondii and Bacillus licheniformis, separately or in co-culture, in wet-processed conilon coffee. Wet fermentation was conducted for 48 h. Mesophilic bacteria, lactic acid bacteria, yeasts, and filamentous fungi were counted during fermentation. The inoculation of B. licheniformis and M. guilliermondii stimulated the multiplication of lactic acid bacteria. Acetic, citric, lactic, oxalic, malic, succinic, tartaric acids, glucose, and fructose were identified in all treatments at different concentrations. Methyl salicylate, 2-heptanol, 2-nonanol, and heptanone were found during fermentation. Methylpyrazine, 2,6-dimethylpyrazine, 2,5-dimethylpyrazine, and 3-ethyl-2,5-dimethylpyrazine identified after roasting assigned notes of "almond" and "chocolate" to the beverages. All treatments were classified as "premium," with the B. licheniformis treatment receiving the highest score. Bacillus licheniformis obtained better performance in fermentation, increasing coffee score and producing volatile compounds that provided positive sensory notes to the beverage.
- Published
- 2023
40. Reducing the effect of beauvericin on neuroblastoma SH-SY5Y cell line by natural products
- Author
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Gaia de Simone, Cristina Juan, Gianni Sagratini, Ana Juan-García, Jordi Mañes, and Giovanni Caprioli
- Subjects
0106 biological sciences ,SH-SY5Y ,Toxicology ,Coffee ,01 natural sciences ,Antioxidants ,Neuroblastoma ,03 medical and health sciences ,chemistry.chemical_compound ,Chlorogenic acid ,Cell Line, Tumor ,Depsipeptides ,Humans ,MTT assay ,Food science ,Mycotoxin ,Biological Products ,0303 health sciences ,Plant Extracts ,Chemistry ,business.industry ,010604 marine biology & hydrobiology ,030302 biochemistry & molecular biology ,food and beverages ,Mycotoxins ,Beauvericin ,Cell culture ,Polyphenol ,Brewing ,business - Abstract
In the present work, different natural compounds from coffee by-product extracts (coffee silverskin and spent coffee) rich in polyphenols, was investigated against beauvericin (BEA) induced-cytotoxicity on SH-SY5Y cells. Spent coffee arise as waste products through the production of instant coffee and coffee brewing; while the silverskin is a tegument which is removed and eliminated with toasting coffee grains. First of all, polyphenol extraction methods, measurement of total polyphenols content and its identification were carried out. Afterwards evaluating in vitro effects with MTT assay on SH-SY5Y cells of coffee by-product extracts and mycotoxins at different concentrations and exposure times was performed. TPC in silverskin coffee by-product extracts was >10 times higher than in spent coffee by-product extracts. Chlorogenic acid was the majority polyphenol detected. Viability for BEA reached IC50 values at 72h (2.5 μM); boiling water silverskin coffee extract reached the highest viability also in pre-treatment BEA exposure and compared with MeOH and MeOH:H2O (v/v, 50:50) extracts. These results in SH-SY5Y cells highlight the use of such residues as supplements or bioactive compounds in the future.
- Published
- 2020
41. Ochratoxin A and citrinin in green coffee and dietary supplements with green coffee extract
- Author
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Iwona Ałtyn, Robert Kosicki, Jan Grajewski, Magdalena Twarużek, and Justyna Kwiatkowska-Giżyńska
- Subjects
0106 biological sciences ,Ochratoxin A ,Dietary supplement ,Food Contamination ,Toxicology ,Coffee ,01 natural sciences ,03 medical and health sciences ,chemistry.chemical_compound ,Food science ,Green coffee ,Mycotoxin ,0303 health sciences ,biology ,Plant Extracts ,Maximum level ,010604 marine biology & hydrobiology ,030302 biochemistry & molecular biology ,biology.organism_classification ,Ochratoxins ,Citrinin ,chemistry ,Green coffee extract ,Dietary Supplements ,Penicillium - Abstract
The aim of this study was to determine the degree of mold contamination and mycotoxin levels in commercially available green coffee products and dietary supplements with green coffee extract. The study included 34 samples from green coffee products: raw beans (n = 16), ground coffee (n = 15) and instant coffee (n = 3), as well as 22 samples from dietary supplements in form of capsules (n = 19), tablets (n = 2) and sachets (n = 1). Total mold count was determined with spread-plate method. Anamorphic mold were identified based on their microscopic morphology and the type of sporulation. Concentrations of mycotoxins, ochratoxin A and citrinin, were quantified by means of HPLC-fluorescence detection. Molds, typically Aspergillus spp. and Penicillium spp., were found in 94% of green coffee beans, 100% of ground and instant coffee samples, and 55% of dietary supplement samples. None of the samples contained detectable levels of citrinin. Ochratoxin A (0.4 ng/g) was detected in only one sample of raw green coffee beans, but in up to 40% and 67% of ground and instant coffee samples, respectively. Mean concentrations of ochratoxin A in ground and instant coffee samples were 3.28 ng/g and 4.09 ng/g, respectively, and maximum concentrations amounted to 6.65 ng/g and 7.44 ng/g, respectively. Ochratoxin A (mean concentration 9.60 ng/g, maximum level 31.4 ng/g) was also detected in up to 58% of the supplement capsules, but in none of tablets and sachets.
- Published
- 2020
42. Green solid-phase microextraction fiber coating based on the metal-organic framework CIM-80(Al): Analytical performance evaluation in direct immersion and headspace using gas chromatography and mass spectrometry for the analysis of water, urine and brewed coffee
- Author
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Idaira Pacheco-Fernández, Juan H. Ayala, Jorge Pasán, Verónica Pino, and Manuel Rentero
- Subjects
Sorbent ,02 engineering and technology ,Urine ,engineering.material ,Solid-phase microextraction ,Mass spectrometry ,Coffee ,01 natural sciences ,Biochemistry ,Gas Chromatography-Mass Spectrometry ,Analytical Chemistry ,chemistry.chemical_compound ,Coating ,Immersion ,Environmental Chemistry ,Fiber ,Polycyclic Aromatic Hydrocarbons ,Metal-Organic Frameworks ,Solid Phase Microextraction ,Spectroscopy ,Chromatography ,Polydimethylsiloxane ,Chemistry ,010401 analytical chemistry ,Extraction (chemistry) ,Water ,021001 nanoscience & nanotechnology ,0104 chemical sciences ,engineering ,Gas chromatography ,0210 nano-technology ,Water Pollutants, Chemical - Abstract
A new solid-phase microextraction (SPME) fiber coating was prepared by the immobilization of the metal-organic framework (MOF) CIM-80(Al) on nitinol wires by a green in situ growth approach, using an aqueous synthetic approach, and without the need of any additional material to ensure the attachment of the MOF to the nitinol support. The coating was used for the development of headspace (HS) and direct immersion (DI) SPME methods in combination with gas chromatography and mass spectrometry (GC-MS) for the determination of polycyclic aromatic hydrocarbons (PAHs) as model compounds. Both methods were optimized and validated using the MOF-based fiber together with the commercial polydimethylsiloxane (PDMS) fiber. The MOF extraction phase exhibited superior analytical performance for most of the PAHs in HS-SPME mode (and particularly for less volatiles), while the PDMS fiber presented better results in the DI-SPME method. The analytical performance of the MOF sorbent coating in HS- and DI-SPME methods was also evaluated in urine and brewed coffee samples, without requiring any pretreatment step apart from dilution for DI-SPME experiments, thus showing suitability of the novel coatings for the analysis of complex samples. The proposed CIM-80(Al) fiber was efficient and biocompatible (for using a low cytotoxic sorbent and a biocompatible core support), and it also demonstrated stability and robustness, with inter-fiber (and inter-day) relative standard deviation values lower than 19%, and reusability for more than 80 extraction cycles using 280 °C as desorption temperature.
- Published
- 2020
43. Coffee Consumption and Lower Liver Stiffness: The Risk for Residual Confounders Should be Considered
- Author
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Lei Xu and Jiarong Xie
- Subjects
medicine.medical_specialty ,Hepatology ,business.industry ,Confounding ,Gastroenterology ,Coffee consumption ,Residual ,Coffee ,Liver ,Risk Factors ,Liver stiffness ,Internal medicine ,Humans ,Medicine ,business - Published
- 2022
44. Contesting Legitimacy in Global Environmental Governance - an Exploration of Transboundary Climate Risk Management in the Brazilian-German Coffee Supply Chain
- Author
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Adis Dzebo and Kevin M. Adams
- Subjects
History ,Polymers and Plastics ,Transboundary Climate Risk ,Transnational governance ,Global Governance ,Adaptation ,Business and International Management ,Coffee ,Legitimacy ,Industrial and Manufacturing Engineering - Abstract
Stronger interconnections between people, ecosystems and economies in a globalized world are changing the scope and nature of global environmental governance. One area where this is becoming increasingly evident is climate change, where there is a growing recognition that climate risks can be transboundary in nature, crossing international borders as people, goods, and capital do. This suggests that a multiplicity of actors – state and non-state – have plausible claims to be engaged in or responsible for the governance of transboundary climate risks (TCRs). However, it is presently unclear on what premises a global governance institution to do so might be constructed and the roles various actors may play therein. This absence of established roles and norms creates a space for political contestation with legitimacy at its center. In this paper, we unpack the contested nature of legitimacy by examining the governance of TCRs in agricultural supply-chains. Empirically, we analyze 41 semi-structured interviews across the Brazilian-German coffee supply chain in an effort to characterize the primary modes of governance available to manage TCRs and their perceived institutional sources of legitimacy. We identify five distinct governance pathways, each underpinned by a distinct operationalization of legitimacy. These governance pathways are not necessarily mutually exclusive; it is plausible for several to co-exist, though the relative balance between their importance in a given context may vary widely. We argue that these five pathways and the role of legitimacy in navigating their differences are transferrable to other challenges in global environmental governance. Further, we argue that legitimacy is best understood as an object of political contestation, wherein actors deploy various sources of legitimacy differently in an effort to legitimize their preferred approach to TCR management, delegitimize others, and advance their own vision of just global environmental governance.
- Published
- 2022
45. Adverse Events Reported to the United States Food and Drug Administration Related to Caffeine-Containing Products
- Author
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Andrew R. Jagim, Jacob L. Erickson, Karen M. Fischer, Chad M. Kerksick, and Patrick S. Harty
- Subjects
Adult ,Male ,medicine.medical_specialty ,Adolescent ,Carbonated Beverages ,Coffee ,Odds ,Young Adult ,Adverse Event Reporting System ,Weight loss ,Caffeine ,Adverse Drug Reaction Reporting Systems ,Humans ,Medicine ,Young adult ,Child ,Adverse effect ,Aged ,Aged, 80 and over ,Tea ,United States Food and Drug Administration ,business.industry ,Infant ,Retrospective cohort study ,General Medicine ,Emergency department ,Odds ratio ,Middle Aged ,United States ,Child, Preschool ,Dietary Supplements ,Emergency medicine ,Female ,Anti-Obesity Agents ,medicine.symptom ,business - Abstract
Objective To examine differences in the frequency and severity of federally reported adverse events between caffeine-containing and non–caffeine-containing products while also identifying the category of caffeine-containing products associated with the highest frequency and severity of adverse events. Patients and Methods All adverse event reports that met specified eligibility criteria and were submitted to the Center for Food Safety and Applied Nutrition Adverse Event Reporting System between January 1, 2014, and June 29, 2018, were extracted. In this retrospective observational study, the most severe adverse event experienced, an ordinal variable, was categorized into death, life-threatening, hospitalization/disability, and emergency department visit. A nonproportional odds model was used to compare the odds of caffeine-containing products being associated with more severe adverse events relative to a noncaffeine group. The analysis is of data only from those reporting adverse events and may or may not be representative of the entire population exposed to these products, which is not known from the examined data. Results Energy and preworkout products saw a significant increase in the odds of the adverse event experienced being death rather than the other less severe outcomes relative to the noncaffeinated group. Those products, along with weight loss products, had greater odds of the adverse event being death or life-threatening vs the less severe outcomes relative to the noncaffeinated group. Conclusion Caffeine-containing products have a greater association with severe adverse events compared with non–caffeine-containing products. Exposure to preworkout and weight loss products had greater odds of being associated with a more serious adverse event relative to noncaffeinated products. Health care practitioners should use these outcomes to better inform and educate patients about the many factors related to caffeine intake and adverse outcomes.
- Published
- 2020
46. Alcohol, tobacco and coffee consumption and liver disease severity among individuals with Chronic Hepatitis B infection in North America
- Author
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Stephen Liu, Anna S. Lok, Marc G. Ghany, Junyao Wang, Mandana Khalili, Mayur Brahmania, Colina Yim, David Wong, Norah A. Terrault, Bettina E. Hansen, Abdus S. Wahed, and Harry L.A. Janssen
- Subjects
Liver Cirrhosis ,Male ,Specialties of internal medicine ,Alcohol abuse ,Alcohol ,Coffee ,Severity of Illness Index ,chemistry.chemical_compound ,Liver disease ,0302 clinical medicine ,Prevalence ,Hepatitis B e Antigens ,Alanine Transaminase ,General Medicine ,Middle Aged ,Hepatitis B ,RC581-951 ,030220 oncology & carcinogenesis ,Cohort ,Female ,030211 gastroenterology & hepatology ,Adult ,Canada ,medicine.medical_specialty ,Asia ,Adolescent ,Alcohol Drinking ,Black People ,Coffee consumption ,Article ,White People ,Young Adult ,03 medical and health sciences ,Hepatitis B Research Network ,Hepatitis B, Chronic ,Asian People ,Chronic hepatitis ,Internal medicine ,Tobacco ,Tobacco Smoking ,medicine ,Humans ,Aged ,Hepatology ,business.industry ,medicine.disease ,United States ,chemistry ,Africa ,DNA, Viral ,Observational study ,Chronic Hepatitis B ,business - Abstract
Introduction and objectives: The prevalence of alcohol, tobacco, and coffee use and association with liver health among North Americans with Chronic Hepatitis B (CHB) infection has not been well described. Materials and methods: The Hepatitis B Research Network includes an observational study of untreated CHB adults enrolled at 21 sites in the United States and Canada. Alcohol use was categorized as none, moderate, and at-risk based on the definition from the National Institute on Alcohol Abuse and Alcoholism; tobacco use as never, current and former; coffee use as none, 1–2 cups/day, and ≥3 cups/day. Linear regression and linear mixed models were used to associate lifestyle behaviors with ALT and FIB-4 values. Results: 1330 participants met eligibility: 53% males, 71% Asian and the median age was 42 years (IQR: 34–52). Median ALT was 33 U/L (IQR: 22–50), 37% had HBV DNA
- Published
- 2020
47. Coffee Consumption is Associated with a Decreased Risk of Incident Chronic Kidney Disease: A Systematic Review and Meta-analysis of Cohort Studies
- Author
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Patompong Ungprasert and Thatsaphan Srithongkul
- Subjects
Risk ,Funnel plot ,medicine.medical_specialty ,030204 cardiovascular system & hematology ,Lower risk ,Coffee ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Internal medicine ,Odds Ratio ,Internal Medicine ,medicine ,Humans ,030212 general & internal medicine ,Renal Insufficiency, Chronic ,business.industry ,Publication bias ,medicine.disease ,Confidence interval ,Meta-analysis ,Relative risk ,business ,Cohort study ,Kidney disease - Abstract
Background Recent studies have suggested a renal protective effect of coffee consumption against development of chronic kidney disease (CKD) although the results remain inconclusive. This systematic review and meta-analysis aimed to comprehensively investigate this association by summarizing all available data. Methods A systematic review was performed using MEDLINE and EMBASE database from inception to November 2019 to identify all cohort studies that compared the risk of developing CKD after index date among coffee-drinkers versus non-drinkers. Pooled risk ratio and 95% confidence interval (CI) were calculated using random-effect, generic inverse-variance method of DerSimonian and Laird. Results A total of 4 cohort studies comprising of 25,849 participants met the inclusion criteria and were analyzed in the meta-analysis. The meta-analysis found a significantly decreased risk of incident CKD among coffee-drinkers compared with non-drinkers with the pooled risk ratio of 0.87 (95% CI, 0.81-0.95; I2 of 57%). The funnel plot of this study was relatively symmetric and was not indicative of publication bias Conclusions A significant association between coffee consumption and a lower risk of incident CKD was demonstrated in this study.
- Published
- 2020
48. Chemical and physical characterization of spent coffee ground biochar treated by a wet oxidation method for the production of a coke substitute
- Author
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Christien A. Strydom, John R. Bunt, Zelma Maree, 20682972 - Strydom, Christiena Adriana, 20164200 - Bunt, John Reginald, and 25068318 - Maree, Zelma
- Subjects
Blast furnace ,Materials science ,020209 energy ,02 engineering and technology ,010501 environmental sciences ,Raw material ,Coffee ,01 natural sciences ,Biochar ,0202 electrical engineering, electronic engineering, information engineering ,Coal ,Spent coffee grounds ,Biomass ,Wet oxidation ,Coke ,Waste Management and Disposal ,0105 earth and related environmental sciences ,business.industry ,Hydrogen Peroxide ,Pulp and paper industry ,Hydrothermal liquefaction ,Charcoal ,Heat of combustion ,business ,Coke production - Abstract
Coke production relies on the availability, cost and quality of coking coal. Depleting coking coal resources and environmental pressure force the metallurgical industry to search for alternative methods to produce coke. Waste spent coffee grounds (biomass) treated via hydrothermal liquefaction (HTL) is an energy-efficient method to produce biochar. In this study the use of HTL biochar as feedstock for the production of a coke substitute was investigated. Wet oxidation treatment of the prepared biochar samples was done with different wet oxidant hydrogen peroxide concentrations (5, 15, 30%). The biochar was treated for different time durations (0.5, 1, 2, 6 and 24 h) and at different temperatures (room temperature and 80 °C). Thereafter, the various samples were characterized and pyrolysed to obtain a coke substitute. Characterization of the various samples before and after thermal treatment was done using Fourier-transform infrared spectroscopy (FTIR), free swelling index, ultimate and proximate analysis, gross calorific value and compressive strength determination. The investigated characteristics of the produced coke substitute obtained from the pyrolysed biochar treated for 24 h with 30 vol% H2O2 at room temperature, showed the most promising results when compared to blast furnace coke.
- Published
- 2020
49. Effects of Polyphenols in a Mediterranean Diet on Symptoms of Depression: A Systematic Literature Review
- Author
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Janet Schloss, Jessica Bayes, and David Sibbritt
- Subjects
Adult ,Male ,Adolescent ,Mediterranean diet ,MEDLINE ,Medicine (miscellaneous) ,Review ,CINAHL ,Diet, Mediterranean ,Coffee ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Environmental health ,Vegetables ,medicine ,Humans ,030212 general & internal medicine ,Depression (differential diagnoses) ,Aged ,Aged, 80 and over ,Nutrition and Dietetics ,Depression ,business.industry ,Polyphenols ,food and beverages ,Middle Aged ,medicine.disease ,Diet ,Mood ,Systematic review ,Major depressive disorder ,Observational study ,business ,030217 neurology & neurosurgery ,Food Science - Abstract
Depression is a mood disorder which currently affects 350 million individuals worldwide. Recently, research has suggested a protective role of diet for depression. The Mediterranean-style dietary pattern has been highlighted in several systematic reviews as a promising candidate for reducing depressive symptoms. It has been speculated that this could be due to the high polyphenol content of foods commonly found in the diet. Therefore, the aim of this review was to assess the effects of polyphenols found in a Mediterranean diet on the symptoms of depression. A systematic literature review was conducted of original research which assessed the role of polyphenols on the symptoms of depression in humans. The following databases were searched: PROQUEST, SCOPUS (Elsevier), MEDLINE (EBSCO), CINAHL, and EMBase, up to 18 February, 2019. The inclusion criteria consisted of both observational and experimental research in adults aged 18-80 y that assessed depression scores in relation to polyphenol intake. A total of 37 studies out of 12,084 met the full inclusion criteria. Of these, 17 were experimental studies and 20 were observational studies. Several different polyphenols were assessed including those from tea, coffee, citrus, nuts, soy, grapes, legumes, and spices. Twenty-nine of the studies found a statistically significant effect of polyphenols for depression. This review has found both an association between polyphenol consumption and depression risk, as well as evidence suggesting polyphenols can effectively alleviate depressive symptoms. The review uncovered gaps in the literature regarding the role of polyphenols for depressive symptoms in both young adults and men. This review was registered at www.crd.york.ac.uk/PROSPERO as CRD42019125747.
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- 2020
50. The effect of coffee consumption on insulin sensitivity and other biological risk factors for type 2 diabetes: a randomized placebo-controlled trial
- Author
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Derrick Johnston Alperet, Bee Choo Tai, Rob M. van Dam, E-Shyong Tai, Chieh Jason Chou, Salome A. Rebello, Zoey Tay, Christian Darimont, Sharna Si-Ying Seah, Shahram Emady-Azar, and Eric Yin Hao Khoo
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Adult ,Male ,0301 basic medicine ,medicine.medical_specialty ,Placebo-controlled study ,Medicine (miscellaneous) ,030209 endocrinology & metabolism ,Type 2 diabetes ,Overweight ,Lower risk ,Placebo ,Coffee ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Insulin resistance ,Risk Factors ,Internal medicine ,medicine ,Humans ,Insulin ,Aged ,Creatinine ,030109 nutrition & dietetics ,Nutrition and Dietetics ,business.industry ,Type 2 Diabetes Mellitus ,Middle Aged ,medicine.disease ,Diabetes Mellitus, Type 2 ,chemistry ,Female ,Insulin Resistance ,medicine.symptom ,business - Abstract
Background In observational studies, coffee consumption has been consistently associated with a lower risk of type 2 diabetes mellitus. Trials examining the effect of coffee consumption on glucose metabolism have been limited by the use of surrogate insulin sensitivity indices, small sample sizes, lack of blinding, and short follow-up duration. Objectives We aimed to overcome limitations of previously conducted coffee trials in a randomized placebo-controlled trial of the effect of coffee consumption on insulin sensitivity. Methods We conducted a 24-wk randomized placebo-controlled trial in 126 overweight, non-insulin sensitive (HOMA-IR ≥1.30), Chinese, Malay, and Asian-Indian males and females aged 35-69 y. Participants were randomly assigned to receive 4 cups of instant regular coffee (n = 62) or 4 cups of a coffee-like placebo beverage (n = 64) per day. The primary outcome was the amount of glucose metabolized per kilogram of body weight per minute (Mbw) assessed during steady-state conditions with a hyperinsulinemic euglycemic clamp. Secondary outcomes included other clamp-based insulin sensitivity measures, biological mediators of insulin sensitivity, and measures of fasting glucose metabolism. Results Coffee consumption did not significantly change insulin sensitivity compared with placebo (percentage mean difference in Mbw = 4.0%; 95% CI: -8.3, 18.0%; P = 0.53). Furthermore, no significant differences in fasting plasma glucose (2.9%; 95% CI: -0.4, 6.3%; P = 0.09) or biological mediators of insulin resistance, such as plasma adiponectin (2.3%; 95% CI: -1.4, 6.2%; P = 0.22), were observed between coffee and placebo groups over 24 wk of intervention. Participants in the coffee arm experienced a loss of fat mass (FM) (-3.7%; 95% CI: -6.3, -1.1%; P = 0.006) and reduction in urinary creatinine concentrations (-21.2%; 95% CI: -31.4, -9.5%; P = 0.001) compared with participants in the placebo arm over 24 wk of intervention. Conclusions Consuming 4 cups/d of caffeinated coffee for 24 wk had no significant effect on insulin sensitivity or biological mediators of insulin resistance but was associated with a modest loss of FM and reduction in urinary creatinine concentrations.This trial was registered at clinicaltrials.gov as NCT01738399. Registered on November 28, 2012. Trial sponsor: Nestle Research, Lausanne, Switzerland. Trial site: National University of Singapore.
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- 2020
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