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6 results on '"Cocozza, Sara"'

1. The combination of UCP3–55CT and PPARγ2Pro12Ala polymorphisms affects BMI and substrate oxidation in two diabetic populations

Author

LAPICE, EMANUELA, COCOZZA, SARA, PINELLI, MICHELE, GIACCO, ANGELA, RIVELLESE, ANGELA ALBAROSA, RICCARDI, GABRIELE, VACCARO, OLGA, Monticelli, A., Massimino, E., Cocozza, S., Riccardi, G., Vaccaro, O., Lapice, Emanuela, Monticelli, A., Cocozza, Sara, Pinelli, Michele, Massimino, E., Giacco, Angela, Rivellese, ANGELA ALBAROSA, Riccardi, Gabriele, Vaccaro, Olga, Cocozza, S., Riccardi, G., and Vaccaro, O.

Subjects
Male, 0301 basic medicine, Cross-sectional study, Endocrinology, Diabetes and Metabolism, Medicine (miscellaneous), Type 2 diabetes, Weight Gain, Type 2 diabete, Body Mass Index, 0302 clinical medicine, Gene Frequency, Genotype, Nutrition and Dietetic, Uncoupling Protein 3, Aged, 80 and over, Genetics, education.field_of_study, Nutrition and Dietetics, Homozygote, Middle Aged, Phenotype, Female, medicine.symptom, Cardiology and Cardiovascular Medicine, Oxidation-Reduction, Adult, Heterozygote, medicine.medical_specialty, Population, 030209 endocrinology & metabolism, Biology, BMI, 03 medical and health sciences, Internal medicine, Dietary Carbohydrates, medicine, Humans, Genetic Predisposition to Disease, Obesity, Polymorphism, education, Allele frequency, Genetic Association Studies, Aged, Polymorphism, Genetic, medicine.disease, Dietary Fats, PPAR gamma, Cross-Sectional Studies, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, Energy Metabolism, Body mass index, Weight gain
Abstract

BACKGROUND AND AIM: To evaluate the combined contribution of UCP3-55CT and PPAR?2 Pro12Ala polymorphisms as correlates of BMI, energy expenditure (REE) and substrate oxidation in people with type 2 diabetes. METHODS AND RESULTS: Two independent population with type 2 diabetes were studied: population A, n = 272; population B, n = 269. Based on both UCP3 and PPAR?2 genotypes three groups were created. Carriers of the PPAR?2 Pro12Ala in combination with the CC genotype of UCP3 (ProAla/CC, group 1); carriers of only one of these genotypes (either CC/ProPro or CT-TT/ProAla, group 2); people with neither variants (CT-TT/ProPro, group 3). In both populations BMI (kg/m(2)) was highest in group 1, intermediate in group 2 and lowest in group 3, independent of energy intake (i.e 35.3 ± 6.7 vs 33.4 ± 5.4 vs 31.8 ± 3, p < 0.02, population A; 32.4 ± 4.2 vs 31.7 ± 3.8 vs 30.1 ± 2.7; p < 0.03, population B). People with the ProAla/CC genotype (group 1) showed similar REE, but lower lipid oxidation (10.9 vs 13.9 g/kg fat free mass/day; p = 0.04) and higher carbohydrate oxidation (23.6 vs 15.6 g/kg fat free mass/day; p = 0.02) than carriers of other genotypes. CONCLUSIONS: The combination of UCP3-55 CC and PPAR?2 Pro12Ala genotypes is associated with significantly higher BMI than other PPAR?2-UCP3 genotype combinations, partly due to a reduced ability in lipids oxidation. The relative importance of these mechanism(s) may be different in non diabetic people. Copyright © 2016 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

Published
2016
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2. Practical Impact of New Diastolic Recommendations on Noninvasive Estimation of Left Ventricular Diastolic Function and Filling Pressures

Author

Sorrentino, Regina, primary, Esposito, Roberta, additional, Santoro, Ciro, additional, Vaccaro, Andrea, additional, Cocozza, Sara, additional, Scalamogna, Maria, additional, Lembo, Maria, additional, Luciano, Federica, additional, Santoro, Alessandro, additional, Trimarco, Bruno, additional, and Galderisi, Maurizio, additional

Published
2020
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3. Polyphenol intake and cardiovascular risk factors in a population with type 2 diabetes: The TOSCA.IT study

Author

Vitale, Marilena, primary, Vaccaro, Olga, additional, Masulli, Maria, additional, Bonora, Enzo, additional, Del Prato, Stefano, additional, Giorda, Carlo B., additional, Nicolucci, Antonio, additional, Squatrito, Sebastiano, additional, Auciello, Stefania, additional, Babini, Anna C., additional, Bani, Laura, additional, Buzzetti, Raffaella, additional, Cannarsa, Emanuela, additional, Cignarelli, Mauro, additional, Cigolini, Massimo, additional, Clemente, Gennaro, additional, Cocozza, Sara, additional, Corsi, Laura, additional, D'Angelo, Federica, additional, Dall'Aglio, Elisabetta, additional, Di Cianni, Graziano, additional, Fontana, Lucia, additional, Gregori, Giovanna, additional, Grioni, Sara, additional, Giordano, Carla, additional, Iannarelli, Rossella, additional, Iovine, Ciro, additional, Lapolla, Annunziata, additional, Lauro, Davide, additional, Laviola, Luigi, additional, Mazzucchelli, Chiara, additional, Signorini, Stefano, additional, Tonutti, Laura, additional, Trevisan, Roberto, additional, Zamboni, Chiara, additional, Riccardi, Gabriele, additional, and Rivellese, Angela A., additional

Published
2017
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4. Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial

Author

Vaccaro, Olga, primary, Masulli, Maria, additional, Nicolucci, Antonio, additional, Bonora, Enzo, additional, Del Prato, Stefano, additional, Maggioni, Aldo P, additional, Rivellese, Angela A, additional, Squatrito, Sebastiano, additional, Giorda, Carlo B, additional, Sesti, Giorgio, additional, Mocarelli, Paolo, additional, Lucisano, Giuseppe, additional, Sacco, Michele, additional, Signorini, Stefano, additional, Cappellini, Fabrizio, additional, Perriello, Gabriele, additional, Babini, Anna Carla, additional, Lapolla, Annunziata, additional, Gregori, Giovanna, additional, Giordano, Carla, additional, Corsi, Laura, additional, Buzzetti, Raffaella, additional, Clemente, Gennaro, additional, Di Cianni, Graziano, additional, Iannarelli, Rossella, additional, Cordera, Renzo, additional, La Macchia, Olga, additional, Zamboni, Chiara, additional, Scaranna, Cristiana, additional, Boemi, Massimo, additional, Iovine, Ciro, additional, Lauro, Davide, additional, Leotta, Sergio, additional, Dall'Aglio, Elisabetta, additional, Cannarsa, Emanuela, additional, Tonutti, Laura, additional, Pugliese, Giuseppe, additional, Bossi, Antonio C, additional, Anichini, Roberto, additional, Dotta, Francesco, additional, Di Benedetto, Antonino, additional, Citro, Giuseppe, additional, Antenucci, Daniela, additional, Ricci, Lucia, additional, Giorgino, Francesco, additional, Santini, Costanza, additional, Gnasso, Agostino, additional, De Cosmo, Salvatore, additional, Zavaroni, Donatella, additional, Vedovato, Monica, additional, Consoli, Agostino, additional, Calabrese, Maria, additional, di Bartolo, Paolo, additional, Fornengo, Paolo, additional, Riccardi, Gabriele, additional, Vaccaro, Olga, additional, Maggioni, Aldo Pietro, additional, D'Angelo, Federica, additional, Giansanti, Roberto, additional, Tanase, Laura, additional, Lanari, Luigi, additional, Testa, Ivano, additional, Pancani, Francesca, additional, Ranchelli, Anna, additional, Vagheggi, Paolo, additional, Scatona, Alessia, additional, Fontana, Lucia, additional, Laviola, Luigi, additional, Tarantino, Lucia, additional, Ippolito, Claudia, additional, Gigantelli, Vittoria, additional, Manicone, Mariangela, additional, Conte, Eleonora, additional, Trevisan, Roberto, additional, Rota, Rossella, additional, Corsi, Anna, additional, Dodesini, Alessandro R., additional, Reggiani, Giulio Marchesini, additional, Montesi, Luca, additional, Mazzella, Natalia, additional, Forlani, Gabriele, additional, Caselli, Chiara, additional, Di Luzio, Raffaella, additional, Mazzotti, Arianna, additional, Aiello, Antimo, additional, Barrea, Angelina, additional, Musto, Antonio, additional, D'Amico, Fiorentina, additional, Sinagra, Tiziana, additional, Longhitano, Sara, additional, Trowpea, Vanessa, additional, Sparti, Maria, additional, Italia, Salvatore, additional, Lisi, Enrico, additional, Grasso, Giuseppe, additional, Pezzino, Vincenzo, additional, Insalaco, Federica, additional, Carallo, Claudio, additional, Scicchitano, Caterina, additional, De Franceschi, Maria Serena, additional, Calbucci, Giovanni, additional, Ripani, Raffaella, additional, Cuneo, Giacomo, additional, Corsi, Simona, additional, Giorda, Carlo B., additional, Romeo, Francesco, additional, Lesina, Annalisa, additional, Comoglio, Marco, additional, Bonetto, Caterina, additional, Robusto, Anna, additional, Nada, Elisa, additional, Asprino, Vincenzo, additional, Cetraro, Rosa, additional, Impieri, Michelina, additional, Lucchese, Giuseppe, additional, Donnarumma, Giovanna, additional, Tizio, Biagio, additional, Lenza, Lazzaro, additional, Paraggio, Pia, additional, Tomasi, Franco, additional, Dozio, Nicoletta, additional, Scalambra, Egle, additional, Mannucci, Edoardo, additional, Lamanna, Caterina, additional, Cignarelli, Mauro, additional, Macchia, Olga La, additional, Fariello, Stefania, additional, Sorrentino, Maria Rosaria, additional, Franzetti, Ivano, additional, Radin, Raffaella, additional, Annunziata, Francesca, additional, Bonabello, Laura Affinito, additional, Durante, Arianna, additional, Dolcino, Mara, additional, Gallo, Fiorenza, additional, Mazzucchelli, Chiara, additional, Aleo, Anna, additional, Melga, Pierluigi, additional, Briatore, Lucia, additional, Maggi, Davide, additional, Storace, Daniela, additional, Cecoli, Francesca, additional, D'Ugo, Ercole, additional, Pupillo, Mario, additional, Baldassarre, Maria Pompea Antonia, additional, Salvati, Filippo, additional, Minnucci, Anita, additional, De Luca, Angelo, additional, Zugaro, Antonella, additional, Santarelli, Livia, additional, Bosco, Angela, additional, Petrella, Vittorio, additional, La Verghetta, Grazia Giovanna, additional, De Gregorio, Antonella, additional, D'Andrea, Settimio, additional, Giuliani, Anna Elisa, additional, Polidoro, w Lorella, additional, Sperandio, Alessandra, additional, Sciarretta, Filomena, additional, Pezzella, Alfonso, additional, Carlone, Angela, additional, Potenziani, Stella, additional, Venditti, Chiara, additional, Foffi, Chiara, additional, Carbone, Salvatore, additional, Cipolloni, Laura, additional, Moretti, Chiara, additional, Leto, Gaetano, additional, Serra, Rosalia, additional, Petrachi, Francesca, additional, Romano, Isabella, additional, Lacaria, Emilia, additional, Russo, Laura, additional, Goretti, Chiara, additional, Sannino, Claudia, additional, Dolci, Maria, additional, Bruselli, Laura, additional, Mori, Mary L., additional, Baccetti, Fabio, additional, Del Freo, Maria, additional, Cucinotta, Domenico, additional, Giunta, Loretta, additional, Ruffo, Maria Concetta, additional, Cannizzaro, Desiree, additional, Pintaudi, Basilio, additional, Perrone, Giovanni, additional, Pata, Pietro, additional, Ragonese, Francesco, additional, Lettina, Gabriele, additional, Mancuso, Teresa, additional, Coppolino, Aldo, additional, Piatti, Pier Marco, additional, Monti, Lucilla, additional, Stuccillo, Michela, additional, Lucotti, Pietro, additional, Setola, Manuela, additional, Crippa, Giulia Valentina, additional, Loi, Cinzia, additional, Oldani, Matteo, additional, Bottalico, Maria Luisa, additional, Pellegata, Beatrice, additional, Bonomo, Matteo, additional, Menicatti, Laura Silvia Maria, additional, Resi, Veronica, additional, Bertuzzi, Federico, additional, Disoteo, Eugenia Olga, additional, Pizzi, Gianluigi, additional, Rivellese, Angela Albarosa, additional, Annuzzi, Giovanni, additional, Capaldo, Brunella, additional, Nappo, Rossella, additional, Auciello, Stefania Michela, additional, Turco, Anna Amelia, additional, Costagliola, Lucia, additional, Corte, Giuseppina Della, additional, Vallefuoco, Pasquale, additional, Nappi, Francesca, additional, Vitale, Marilena, additional, Cocozza, Sara, additional, Ciano, Ornella, additional, Massimino, Elena, additional, Garofalo, Nadia, additional, Avogaro, Angelo, additional, Guarneri, Gabriella, additional, Fedele, Domenico, additional, Sartore, Giovanni, additional, Chilelli, Nino Cristiano, additional, Burlina, Silvia, additional, Bonsembiante, Barbara, additional, Galluzzo, Aldo, additional, Torregrossa, Vittoria, additional, Mancastroppa, Giovanni, additional, Arsenio, Leone, additional, Cioni, Federico, additional, Caronna, Silvana, additional, Papi, Matteo, additional, Babini, Massimiliano, additional, Santeusanio, Fausto, additional, Calagreti, Gioia, additional, Timi, Alessia, additional, Tantucci, Alice, additional, Marino, Cecilia, additional, Ginestra, Federica, additional, Di Biagio, Rosamaria, additional, Taraborelli, Merilda, additional, Miccoli, Roberto, additional, Bianchi, Cristina, additional, Garofolo, Monia, additional, Politi, Konstantina Savina, additional, Penno, Giuseppe, additional, Livraga, Stefania, additional, Calzoni, Fabio, additional, Mancastroppa, Giovanni Luigi Francesco, additional, Corsini, Elisa, additional, Tedeschi, Anna, additional, Gaglianò, Maria Sole, additional, Ippolito, Giulio, additional, Salutini, Elisabetta, additional, Cervellino, Francesco, additional, Natale, Maria, additional, Salvatore, Vita, additional, Zampino, Armando, additional, Sinisi, Rosa, additional, Arcangeli, Adolfo, additional, Zogheri, Alessia, additional, Guizzotti, Sandra, additional, Longo, Rossella, additional, Di Bartolo, Paolo, additional, Pellicano, Francesca, additional, Scolozzi, Patrizia, additional, Termine, Simona, additional, Luberto, Alessandra, additional, Ballardini, Giorgio, additional, Trojani, Cristina, additional, Mazzuca, Paolo, additional, Bruglia, Matteo, additional, Ciamei, Monica, additional, Genghini, Silvia, additional, Zannoni, Chiara, additional, Vitale, Martina, additional, Rangel, Graziela, additional, Salvi, Laura, additional, Zappaterreno, Alessandra, additional, Cordone, Samantha, additional, Simonelli, Paola, additional, Meggiorini, Marilla, additional, Frasheri, Aurora, additional, Di Pippo, Clelia, additional, Maglio, Cristina, additional, Mazzitelli, Giulia, additional, Rinaldi, Maria Elena, additional, Galli, Angelica, additional, Romano, Maria, additional, D'Angelo, Paola, additional, Suraci, Concetta, additional, Bacci, Simonetta, additional, Palena, Antonio Pio, additional, Genovese, Stefano, additional, Mancino, Monica, additional, Rondinelli, Maurizio, additional, Capone, Filippo, additional, Calabretto, Elisabetta, additional, Bulgheroni, Monica, additional, Bucciarelli, Loredana, additional, Ceccarelli, Elena, additional, Fondelli, Cecilia, additional, Santacroce, Clorinda, additional, Guarino, Elisa, additional, Nigi, Laura, additional, Lalli, Carlo, additional, Di Vizia, Giovanni, additional, Scarponi, Maura, additional, Montani, Valeria, additional, Di Bernardino, Paolo, additional, Romagni, Paola, additional, Dolcetti, Katia, additional, Forte, Elisa, additional, Tamburo, Lucilla, additional, Perin, Paolo Cavallo, additional, Prinzis, Tania, additional, Gruden, Gabriella, additional, Bruno, Graziella, additional, Zucco, Chiara, additional, Perotta, Massimo, additional, Marena, Saverio, additional, Monsignore, Simona, additional, Panero, Francesco, additional, Ponzi, Fulvia, additional, Bossi, Antonio Carlo, additional, Carpinteri, Rita, additional, Casagrande, Maria Linda, additional, Coletti, Maria Francesca, additional, Balini, Annalisa, additional, Filopanti, Marcello, additional, Madaschi, Sara, additional, Pulcina, Anna, additional, Grimaldi, Franco, additional, Venturini, Giorgio, additional, Agus, Sandra, additional, Pagnutti, Stefania, additional, Guidotti, Francesca, additional, Cavarape, Alessandro, additional, Cigolini, Massimo, additional, Pichiri, Isabella, additional, Brangani, Corinna, additional, Fainelli, Giulia, additional, Tomasetto, Elena, additional, Zoppini, Giacomo, additional, Galletti, Anna, additional, Perrone, Dominica, additional, Capra, Claudio, additional, Bianchini, Francesca, additional, Ceseri, Martina, additional, Di Nardo, Barbara, additional, Sasso, Elisa, additional, Bartolomei, Barbara, additional, Suliman, Irina, additional, Fabbri, Gianna, additional, Romano, Geremia, additional, Maturo, Nicola, additional, Nunziata, Giuseppe, additional, Capobianco, Giuseppe, additional, De Simone, Giuseppina, additional, Villa, Valeria, additional, Rota, Giuseppe, additional, Pentangelo, Carmine, additional, Carbonara, Ornella, additional, Caiazzo, Gennaro, additional, Cutolo, Michele, additional, Sorrentino, Tommasina, additional, Mastrilli, Valeria, additional, Amelia, Umberto, additional, Masi, Stefano, additional, Corigliano, Gerardo, additional, Gaeta, Iole, additional, Armentano, Vincenzo, additional, Calatola, Pasqualino, additional, Capuano, Gelsomina, additional, Angiulli, Bruno, additional, Auletta, Pasquale, additional, Petraroli, Ettore, additional, Iodice, Cinzia E., additional, and Agrusta, Mariano, additional

Published
2017
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6. Test meals rich in marine long-chain n-3 polyunsaturated fatty acids increase postprandial chylomicron response

Author

E. Griffo, Gabriele Riccardi, Anna Mangione, Paola Cipriano, S. Cocozza, L. Di Marino, Lutgarda Bozzetto, Lidia Patti, Angela A. Rivellese, G. Della Pepa, Giovanni Annuzzi, Griffo, Ettore, Di Marino, L, Patti, Lidia, Bozzetto, Lutgarda, Annuzzi, Giovanni, Cipriano, Paola, Mangione, Anna, DELLA PEPA, Giuseppe, Cocozza, Sara, Riccardi, Gabriele, and Rivellese, ANGELA ALBAROSA

Subjects
Polyphenol, Adult, Male, medicine.medical_specialty, Very low-density lipoprotein, Endocrinology, Diabetes and Metabolism, Triglyceride, Chylomicron, chemistry.chemical_compound, Endocrinology, Glucagon-Like Peptide 1, Internal medicine, Chylomicrons, Fatty Acids, Omega-3, medicine, Humans, High-risk subject, Meal, Meals, Dietary Fat, Triglycerides, Aged, chemistry.chemical_classification, Nutrition and Dietetics, Chemistry, Cholesterol, Polyphenols, food and beverages, Fatty acid, Middle Aged, Postprandial Period, Dietary Fats, Eicosapentaenoic acid, Long-chain n-3 polyunsaturated fatty acid, Diet, Postprandial, Postprandial lipid response, Female, lipids (amino acids, peptides, and proteins), GLP-1, Apolipoprotein B-48, Human, Polyunsaturated fatty acid
Abstract

Postprandial lipid abnormalities are considered an independent cardiovascular risk factor. Hence, it is important to find nutritional strategies that are able to positively influence these abnormalities. Since the effect of n-3 polyunsaturated fatty acids (PUFA) and polyphenols on postprandial lipids in humans is still under debate, we evaluated the acute response of triglyceride-rich lipoproteins to test meals that are naturally rich in polyphenols and/or marine long-chain (LC) n-3 PUFAs. We hypothesized that LC n-3 PUFA would have a different effect on chylomicron and very low density lipoproteins when compared with polyphenols or their combination. We randomly assigned 78 individuals who were at high cardiometabolic risk to 4 isoenergetic diets. These diets only differed in amount of LC n-3 PUFA and/or polyphenols. Prior to starting the intervention, each subject underwent a test meal similar to the type of diet assigned: low in LC n-3 PUFA and polyphenols (control), rich in LC n-3 PUFA and low in polyphenols, rich in polyphenols and low in LC n-3 PUFA, or rich in both. Blood samples were taken before and up to 6 hours after the test meal in order to evaluate cholesterol and triglycerides (plasma and triglyceride-rich lipoprotein), apolipoprotein B-48 (large very low density lipoprotein), glucagon-like peptide-1, and free fatty acid plasma levels. The levels of chylomicron cholesterol and triglyceride in response to the test meal rich in LC n-3 PUFA were significantly higher than after the control meal (P = .037 and P = .018); there was no difference in the other variables. In conclusion, this study indicates that acute administration of marine LC n-3 PUFA increases postprandial chylomicron response in contrast with their lowering chronic effects. These differences underline the importance of understanding the acute and chronic effects of nutritional, as well as of other types of, interventions.

Published
2014
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