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Your search keyword '"Coche, J. C."' showing total 5 results
Start Over Author "Coche, J. C." Publisher elsevier bv
5 results on '"Coche, J. C."'

1. 397P R-IMMUNE interim analysis: A phase Ib/II study to evaluate safety and efficacy of atezolizumab combined with radio-chemotherapy in a preoperative setting for patients with localized rectal cancer

Author

Carrasco, J., primary, Schröder, D., additional, Sinapi, I., additional, De Cuyper, A., additional, Beniuga, G., additional, Delmarcelle, S., additional, Laethem, J-L. van, additional, Huyghe, N., additional, Bar, I., additional, Hendlisz, A., additional, Haustermans, K.M., additional, Delaunoit, T., additional, Coche, J-C., additional, Van Ooteghem, G., additional, Boulanger, A-S., additional, Baldin, P., additional, and Van den Eynde, M., additional

Published
2021
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2. Profile of pediatric Crohn's disease in Belgium

Author

UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - SSS/IREC/PEDI - Pôle de Pédiatrie, UCL - (SLuc) Service de gastro-entérologie, UCL - (MGD) Service de gastro-entérologie, UCL - (SLuc) Service de gastro-entérologie et hépatologie pédiatrique, De Greef, E, Mahachie John, J M, Hoffman, I, Smets, Françoise, Van Biervliet, S, Scaillon, M, Hauser, B, Paquot, I, Alliet, P, Arts, W, Dewit, Olivier, Peeters, H, Baert, F, D'Haens, G, Rahier, Jean-François, Etienne, I, Bauraind, O, Van Gossum, A, Vermeire, S, Fontaine, F, Muls, V, Louis, E, Van de Mierop, F, Coche, J C, Van Steen, K, Veereman, G, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - SSS/IREC/PEDI - Pôle de Pédiatrie, UCL - (SLuc) Service de gastro-entérologie, UCL - (MGD) Service de gastro-entérologie, UCL - (SLuc) Service de gastro-entérologie et hépatologie pédiatrique, De Greef, E, Mahachie John, J M, Hoffman, I, Smets, Françoise, Van Biervliet, S, Scaillon, M, Hauser, B, Paquot, I, Alliet, P, Arts, W, Dewit, Olivier, Peeters, H, Baert, F, D'Haens, G, Rahier, Jean-François, Etienne, I, Bauraind, O, Van Gossum, A, Vermeire, S, Fontaine, F, Muls, V, Louis, E, Van de Mierop, F, Coche, J C, Van Steen, K, and Veereman, G

Abstract

AIM: A Belgian registry for pediatric Crohn's disease, BELCRO, was created. This first report aims at describing disease presentation and phenotype and determining associations between variables at diagnosis and registration in the database. METHODS: Through a collaborative network, children with previously established Crohn's disease and newly diagnosed children and adolescents (under 18 y of age) were recruited over a 2 year period. Data were collected by 23 centers and entered in a database. Statistical association tests analyzed relationships between variables of interest at diagnosis. RESULTS: Two hundred fifty-five patients were included. Median age at diagnosis was 12.5 y (range: 1.6-18 y); median duration of symptoms prior to diagnosis was 3 m (range: 1-12 m). Neonatal history and previous medical history did not influence disease onset nor disease behavior. Fifty three % of these patients presented with a BMI z-score < -1. CRP was an independent predictor of disease severity. Steroids were widely used as initial treatment in moderate to severe and extensive disease. Over time, immunomodulators and biological were prescribed more frequently, reflecting a lower prescription rate for steroids and 5-ASA. A positive family history was the sole significant determinant for earlier use of immunosuppression. CONCLUSION: In Belgium, the median age of children presenting with Crohn's disease is 12.5 y. Faltering growth, extensive disease and upper GI involvement are frequent. CRP is an independent predictive factor of disease activity. A positive family history appears to be the main determinant for initial treatment choice.

Published
2013

3. Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer

Author

Machiels, J-P., primary, Sempoux, C., additional, Scalliet, P., additional, Coche, J-C., additional, Humblet, Y., additional, Van Cutsem, E., additional, Kerger, J., additional, Canon, J-L., additional, Peeters, M., additional, Aydin, S., additional, Laurent, S., additional, Kartheuser, A., additional, Coster, B., additional, Roels, S., additional, Daisne, J-F., additional, Honhon, B., additional, Duck, L., additional, Kirkove, C., additional, Bonny, M-A., additional, and Haustermans, K., additional

Published
2007
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4. Phase II study of preoperative oxaliplatin, capecitabine and external beam radiotherapy in patients with rectal cancer: the RadiOxCape study

Author

Machiels, J.-P., primary, Duck, L., additional, Honhon, B., additional, Coster, B., additional, Coche, J.-C., additional, Scalliet, P., additional, Humblet, Y., additional, Aydin, S., additional, Kerger, J., additional, Remouchamps, V., additional, Canon, J.-L., additional, Van Maele, P., additional, Gilbeau, L., additional, Laurent, S., additional, Kirkove, C., additional, Octave-Prignot, M., additional, Baurain, J.-F., additional, Kartheuser, A., additional, and Sempoux, C., additional

Published
2005
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