14 results on '"Cai-Yun Wang"'
Search Results
2. Preparation and characterization of solid lipid nanoparticles loaded with salmon calcitonin phospholipid complex
- Author
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Zhang Ying, Gao Yan, Lan Wang, Ke-Rui Zhang, Cai-Yun Wang, and Fu Haijuan
- Subjects
Aqueous solution ,Chromatography ,Chemistry ,Dispersity ,Pharmaceutical Science ,02 engineering and technology ,021001 nanoscience & nanotechnology ,030226 pharmacology & pharmacy ,Dosage form ,Bioavailability ,03 medical and health sciences ,Subcutaneous injection ,0302 clinical medicine ,Solid lipid nanoparticle ,Zeta potential ,Particle size ,0210 nano-technology - Abstract
Salmon calcitonin phospholipid complex loaded-solid lipid nanoparticles (sCT-PC-SLNs) were prepared from Salmon calcitonin phospholipid complex (sCT-PC) by a film dispersion method. The formulation was optimized by the Box-Behnken response surface design using quality properties such as particle size, polydispersity index (PDI), zeta potential value, entrapment efficiency (EE), and drug loading capacity (DL). The relative bioavailability of different dosage forms of salmon calcitonin (sCT) were calculated separately for plasma calcium percentage of SD female rats after subcutaneous injection and colonic administration. The results show that each dosage form offers reduced plasma calcium levels after colonic administration, except for blank loaded-solid lipid nanoparticles (SLN). The relative bioavailability (0.32 ± 0.17%) for sCT-PC-SLN is twice as high as that of aqueous sCT solution (0.16 ± 0.03%), as well as values for Salmon calcitonin loaded-solid lipid nanoparticles (sCT-SLN) (0.15 ± 0.01%); these results are statistically significant. Compared to SLN, uptake of sCT in a rat colon can be greatly improved by phospholipid complex loaded-solid lipid nanoparticles (PC-SLN). The new dosage form developed here overcomes the low EE of the water-soluble drug, enhances the EE of SLN, and reduces the degradation of gastrointestinal enzymes due to its encapsulation in lipids.
- Published
- 2019
3. Incorporating attapulgite nanorods into graphene oxide nanofiltration membranes for efficient dyes wastewater treatment
- Author
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Xiaoliang Zhang, Wen-Juan Zeng, Cai-Yun Wang, Xi Chen, and Ting-Ting Jiang
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Materials science ,Graphene ,Oxide ,Filtration and Separation ,02 engineering and technology ,021001 nanoscience & nanotechnology ,Analytical Chemistry ,Membrane technology ,law.invention ,Contact angle ,chemistry.chemical_compound ,Membrane ,020401 chemical engineering ,chemistry ,Chemical engineering ,law ,Nanorod ,Nanofiltration ,0204 chemical engineering ,0210 nano-technology ,Filtration - Abstract
Graphene oxide/attapulgite (GO/APT) composite membranes were successfully fabricated by the vacuum-assisted filtration for efficient dyes wastewater treatment. By characterization of FTIR, XPS, Raman, XRD and FESEM, APT nanorods were confirmed to be incorporated into GO laminar layers via grafting modification, which would influence GO interlayer distance (d-spacing), membrane surface microstructure (laminate morphology, structure, and hydrophilicity) and even water separation performance. Comparison of those of pristine GO membrane, the calculated d-spacing of GO/APT membranes gradually increased from 0.90 nm to 1.07 nm, while water contact angles decreased from 71.0° to 43.3° with the increasing APT/GO ratios. Moreover, GO/APT membranes exhibited rough hierarchical microstructure and higher surface hydrophilicity, which was in conjunction with larger interlayer spacing to synergistically improve separation performance. The water permeated flux increased from 3.4 of pristine GO membrane to 13.3 L m−2 h−1 of GO/APT membrane with preserving high rejection nearly to 100% for 7.5 mg L−1 Rh B wastewater under optimized conditions. Similarly, membrane thickness, dye concentrations and separating species in feed solutions were also found to affect membrane separation performance. Dye molecules were efficiently rejected through GO/APT nanofiltration membranes by the synergistic separation mechanism: size exclusion effect because of the unimpeded water channels formed into 3D network laminate structure, and electrostatic interactions between the oxygen-containing functional groups on membrane surface and charged molecules. Such these GO/APT membranes demonstrated efficiently separation properties and thus provided new insight into the potential applications in water purification and dyes wastewater treatment.
- Published
- 2019
4. Mid–Neoproterozoic collision of the Tarim Craton with the Yili–Central Tianshan Block towards the final assembly of Supercontinent Rodinia: A new model
- Author
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Hong-Xiang Wu, Feng-Qi Zhang, Yildirim Dilek, Han-Lin Chen, Cai-Yun Wang, Xiu-Bin Lin, Xiao-Gan Cheng, and Kong-Yang Zhu
- Subjects
General Earth and Planetary Sciences - Published
- 2022
5. Mixed lanthanide coordination polymers for temperature sensing and enhanced NdIII NIR luminescence
- Author
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Ali Alhafeez Abdulrheem Shamshooma, Wei Xi, Cai-Yun Wang, Xue-Qin Song, Mo Zhang, and Huan-Huan Meng
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chemistry.chemical_classification ,Lanthanide ,Materials science ,010405 organic chemistry ,Ligand ,Biophysics ,Salicylamide ,General Chemistry ,Polymer ,Atmospheric temperature range ,010402 general chemistry ,Condensed Matter Physics ,01 natural sciences ,Biochemistry ,Atomic and Molecular Physics, and Optics ,0104 chemical sciences ,chemistry ,Excited state ,medicine ,Physical chemistry ,Molecule ,Luminescence ,medicine.drug - Abstract
Three LnIII coordination polymers, [Ln2L3(NO3)3]n·2CH3COOCH2CH3 (Ln = Nd (Nd2L3), Eu (Eu2L3), Tb (Tb2L3)), following coordination-assembly reactions involving a new bi-monodentate salicylamide ligand, L = 1,4-bis[(2΄-thenylaminoformyl)phenoxyl]methyl}-benzene, have been successfully synthesized. Among them, Nd2L3 and Tb2L3 were structurally authenticated by single-crystal X-ray diffraction and the results indicate both Nd2L3 and Tb2L3 are one-dimensional corrugated blockchains with LnIII containing 64-membered block loops filled by ethyl acetate molecules alternating in nearly orthogonal directions. For they are isomorphous, two binary co-doped lanthanide coordination polymers, Tb0.965Eu1.035L3 and Tb0.717Nd1.283L3 are obtained. Luminescent studies indicate that Tb0.965Eu1.035L3 exhibits a temperature recognition property with the significantly high sensitivity of 2.61% per K in the 296–386 K temperature range upon excitation at 345 nm as well as white emission when excited in the range of 370–390 nm. Tb0.717Nd1.283L3 shows enhanced NdIII-centred NIR luminescence and diminished TbIII-centred luminescence as compared to those of Nd2L3 and Tb2L3. The results presented herein show that the energy transfer from TbIII to both EuIII and NdIII has been successfully achieved in Tb0.965Eu1.035L3 and Tb0.717Nd1.283L3. Generally speaking, this work explores the potential applications of lanthanide-based coordination polymers based on multi-monodentate salicylamide ligand in the area of thermal sensing.
- Published
- 2018
6. Pentanuclear sandwich-type ZnII-LnIII clusters based on a new Salen-like salicylamide ligand: Structure, near-infrared emission and magnetic properties
- Author
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Pan-Pan Liu, Cai-Yun Wang, Xue-Qin Song, and Mo Zhang
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010405 organic chemistry ,Chemistry ,Stereochemistry ,Ligand ,Relaxation (NMR) ,Salicylamide ,Crystal structure ,010402 general chemistry ,01 natural sciences ,Magnetic susceptibility ,0104 chemical sciences ,Ion ,Inorganic Chemistry ,Magnetization ,Crystallography ,Materials Chemistry ,medicine ,Antiferromagnetism ,Physical and Theoretical Chemistry ,medicine.drug - Abstract
Two new sandwich-type heterometallic ZnII-LnIII clusters based on a methoxy substituted salicylamide Salen-like ligand, [Zn2Er3(HL)2(H2L)2(OH)2(NO3)3](NO3)2·2CH3OH (Zn2Er3), [Zn2Yb3(HL)2(H2L)2(OH)2 (NO3)3](NO3)2·2CH3OH (Zn2Yb3), H3L = 1-(2-hydroxy-4-methoxy-benzamido)-2-(2-hydroxy-3-methoxy-benzylideneamino)-ethane, were prepared and structurally characterized. Single-crystal structure analyses reveal that both compounds are pentanuclear clusters with a hydroxyl bridged trinuclear LnIII3 core swaddled by two ZnII ions, two singly deprotoned H2L− ligands, two doubly deprotoned HL− ligands and three nitrate anions. Photophysical determination indicates that the two ZnII-LnIII compounds display both ligand-centered and near-infrared emission. The magnetic susceptibility measurements reveal that Zn2Er3 displays antiferromagnetic interactions with zero field slow magnetization relaxation diagnostic of single-molecule-magnet (SMM).
- Published
- 2017
7. Structures and magnetic properties of cyclic heterometallic tetranuclear clusters
- Author
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Yuan-Ang Liu, Mo Zhang, Cai-Yun Wang, and Xue-Qin Song
- Subjects
Denticity ,010405 organic chemistry ,Chemistry ,Relaxation (NMR) ,Inorganic chemistry ,Crystal structure ,010402 general chemistry ,01 natural sciences ,Magnetic susceptibility ,0104 chemical sciences ,Inorganic Chemistry ,Crystallography ,Magnetization ,Ferromagnetism ,Materials Chemistry ,Diamagnetism ,Physical and Theoretical Chemistry ,Isostructural - Abstract
A new salicylamide Salen-like multidentate ligand, 1-(2-hydroxy-3-methoxy-benzamido)-2-(2-hydroxy-3-methoxy-benzylideneamino)-ethane (H3L), was synthesised and used to build up heterometallic magnetic clusters. As a result, four new highly thermal stable cyclic tetranuclear heterometallic clusters which were characterized by elemental analysis, X-ray diffraction, IR and TGA measurements, [M2Ln2L2(NO3)4] (M2Ln2, where MII = CuII, NiII and LnIII = TbIII, DyIII), were successfully obtained with high yield under solvothermal conditions. Temperature-dependent magnetic susceptibility measurements exhibit strong ferromagnetic interactions between CuII and LnIII in Cu2Ln2 which were evaluated by comparing their magnetic susceptibilities with those of the isostructural Ni2Ln2 clusters containing diamagnetic NiII ions. Furthermore, alternating-current magnetic susceptibility studies carried out for the four tetranuclear compounds indicate that Cu2Ln2 exhibit interesting slow relaxation of magnetization of the SMM behavior and the effective energy barriers for Cu2Tb2 can be obtained from alternating-current susceptibility measurements by applying an external 2000 Oe direct-current field.
- Published
- 2017
8. Total alkaloids from Alstonia scholaris inhibit influenza a virus replication and lung immunopathology by regulating the innate immune response
- Author
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Yi-Feng Wang, Haiming Jiang, Xin-Xin Chen, Zifeng Yang, Zhi-Hong Jiang, Lihua Cai, Xiao-Dong Luo, Cai-Yun Wang, Jing-Guang Lu, Ruifeng Chen, Ming-Rong Yang, Hongxia Zhou, Runfeng Li, Xiao Wu, Huan-Rong Zhang, Yunceng Weng, and Lihan Shen
- Subjects
Chemokine ,medicine.medical_treatment ,Pharmaceutical Science ,Biology ,Virus Replication ,medicine.disease_cause ,Antiviral Agents ,Virus ,Madin Darby Canine Kidney Cells ,Proinflammatory cytokine ,Microbiology ,03 medical and health sciences ,Alkaloids ,Dogs ,Influenza A Virus, H1N1 Subtype ,0302 clinical medicine ,Orthomyxoviridae Infections ,Immunopathology ,Influenza, Human ,Drug Discovery ,Influenza A virus ,medicine ,Animals ,Humans ,Lung ,030304 developmental biology ,Pharmacology ,0303 health sciences ,Innate immune system ,Anti-Inflammatory Agents, Non-Steroidal ,Pattern recognition receptor ,Immunity, Innate ,Mice, Inbred C57BL ,Cytokine ,Complementary and alternative medicine ,A549 Cells ,030220 oncology & carcinogenesis ,biology.protein ,Cytokines ,Molecular Medicine ,Female ,Alstonia - Abstract
Background Alstonia scholaris is a folk medicine used to treat cough, asthma and chronic obstructive pulmonary disease in China. Total alkaloids (TA) from A. scholaris exhibit anti-inflammatory properties in acute respiratory disease, which suggests their possible anti-inflammatory effect on influenza virus infection. Purpose To assess the clinical use of TA by demonstrating their anti-influenza and anti-inflammatory effects and the possible mechanism underlying the effect of TA on influenza A virus (IAV) infection in vitro and to reveal the inhibitory effect of TA on lung immunopathology caused by IAV infection. Methods Antiviral and anti-inflammatory activities were assessed in Madin-Darby canine kidney (MDCK) and A549 cells and U937-derived macrophages infected with influenza A/PR/8/34 (H1N1) virus. Proinflammatory cytokine levels were measured by real-time quantitative PCR and Bio-Plex assays. The activation of innate immune signaling induced by H1N1 virus in the absence or presence of TA was detected in A549 cells by Western blot. Furthermore, mice were infected intranasally with H1N1 virus and treated with TA (50, 25 and 12.5 mg/kg/d) or oseltamivir (60 mg/kg/d) for 5 days in vivo. The survival rates and body weight were recorded, and the viral titer, proinflammatory cytokine levels, innate immune cell populations and histopathological changes in the lungs were analyzed. Results TA significantly inhibited viral replication in A549 cells and U937-derived macrophages and markedly reduced cytokine and chemokine production at the mRNA and protein levels. Furthermore, TA blocked the activation of pattern recognition receptor (PRR)- and IFN-activated signal transduction in A549 cells. Critically, TA also increased the survival rate, reduced the viral titer, suppressed proinflammatory cytokine production and innate immune cell infiltration and improved lung histopathology in a lethal PR8 mouse model. Conclusion TA exhibits anti-viral and anti-inflammatory effects against IAV infection by interfering with PRR- and IFN-activated signal transduction.
- Published
- 2020
9. Quantitation of ligupurpurosides B and C in rat plasma using HPLC-MS/MS
- Author
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Qian-Qian Chen, Wei Zhang, Suo-Ming Feng, Jianru Guo, and Cai-Yun Wang
- Subjects
Male ,Analyte ,Formic acid ,Analytical chemistry ,Mass spectrometry ,Sensitivity and Specificity ,01 natural sciences ,High-performance liquid chromatography ,Rats, Sprague-Dawley ,Plasma ,chemistry.chemical_compound ,0404 agricultural biotechnology ,Tandem Mass Spectrometry ,Ionization ,Drug Discovery ,Animals ,Protein precipitation ,Glycosides ,Chromatography, High Pressure Liquid ,Chromatography ,Molecular Structure ,010401 analytical chemistry ,Selected reaction monitoring ,04 agricultural and veterinary sciences ,General Medicine ,040401 food science ,Rats ,0104 chemical sciences ,Triple quadrupole mass spectrometer ,Complementary and alternative medicine ,chemistry ,Drugs, Chinese Herbal - Abstract
The present study was designed to develop a sensitive and selective specific high performance liquid chromatography (HPLC)-tandem mass spectrometric method (MS/MS) for the determination of ligupurpurosides B and C in rat plasma. The samples were prepared after protein precipitation and analyzed by liquid chromatography equipped with a C18 column interfaced with a triple quadrupole tandem mass spectrometer using ESI as the ionization source in the negative ion mode. The mobile phase consisted of water (0.01 % formic acid)-methanol (57 : 43, V/V) at the flow rate of 0.3 mL·min(-1). The analytes and internal standard acteoside were both detected by use of multiple reaction monitoring mode. The total run time was 6.0 min. The method was linear in the concentration range of 2.5-500.0 ng·mL(-1) and the lower limit of quantifiation (LLOQ) was 2.5 ng·mL(-1). The intra-day and inter-day relative standard deviations across three validation runs over the entire concentration range were less than 9.8 %. The accuracy determined at three concentrations was within ± 6.1% in terms of relative error. In conclusion, this assay offers advantages in terms of expediency and suitability for the analysis of ligupurpuroside B and ligupurpuroside C in various biological fluids.
- Published
- 2016
10. Quantitation of kudinoside A, kudinoside D and kudinoside F in human plasma using a high performance liquid chromatography–electrospray ionization tandem mass spectrometric method
- Author
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Hongcong Qiu, Qian Qian Chen, Wei Zhang, Liu Buming, Jianru Guo, and Cai-Yun Wang
- Subjects
Spectrometry, Mass, Electrospray Ionization ,Analyte ,Chromatography ,Tandem ,Chemistry ,Electrospray ionization ,Clinical Biochemistry ,Selected reaction monitoring ,Analytical chemistry ,Reproducibility of Results ,Cell Biology ,General Medicine ,Saponins ,Mass spectrometry ,Biochemistry ,Triterpenes ,Analytical Chemistry ,Triple quadrupole mass spectrometer ,Limit of Detection ,Tandem Mass Spectrometry ,Ionization ,Humans ,Protein precipitation ,Chromatography, High Pressure Liquid - Abstract
A sensitive and selective high performance liquid chromatography-tandem mass spectrometric (HPLC-MS/MS) method for the simultaneous determination of kudinoside A, kudinoside D and kudinoside F in human plasma has been firstly developed. Samples were prepared after protein precipitation and analyzed on a C18 column interfaced with a triple quadrupole tandem mass spectrometer. Negative electrospray ionization was employed as the ionization source. The mobile phase consisted of acetonitrile-water (35:65) at the flow rate of 0.3mL/min. The analytes and internal standard Ginsenoside Rb1 were both detected by use of multiple reaction monitoring mode. The method was linear in the concentration range of 2.5-1000.0ng/mL. The lower limit of quantification (LLOQ) was 2.5ng/mL. The intra-and inter-day relative standard deviation across three validation runs over the entire concentration range was less than 12.4%. The accuracy determined at three concentrations was within ±4.9% in terms of relative error. The total run time was 7.0min. This assay offers advantages in terms of expediency, and suitability for the analysis of kudinoside A, kudinoside D and kudinoside F in various biological fluids.
- Published
- 2014
11. The isolation and identification of a light-induced protein in alfalfa sprouts and the cloning of its specific promoter
- Author
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Weizhuo Xu, Su Xin, Song You, Cai-Yun Wang, K. Kakutani, Xin Zhang, Rui-Fang Zhuo, and Liu Xin
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Light ,TATA box ,Molecular Sequence Data ,Photosynthetic Reaction Center Complex Proteins ,CAAT box ,Sequence Homology ,Biology ,Genes, Plant ,Substrate Specificity ,chemistry.chemical_compound ,Gene Expression Regulation, Plant ,Genetics ,Amino Acid Sequence ,Cloning, Molecular ,Promoter Regions, Genetic ,Plastocyanin ,Gene ,Peptide sequence ,Plant Proteins ,Reporter gene ,Base Sequence ,fungi ,food and beverages ,Promoter ,General Medicine ,Molecular biology ,chemistry ,Seedlings ,DNA ,Medicago sativa - Abstract
We used 2D-PAGE to isolate a light-induced protein (AL-A) that is expressed abundantly in light-growth alfalfa sprouts. The seven amino acids of the N-terminal region of the protein were identified, and we searched for the protein in GenBank using the BLAST program. The results of the homology analysis showed that the amino acid sequence of the isolated protein is most similar to one from a pea plastocyanin. To identify the protein, we amplified and sequenced the DNA fragment encoding AL-A from genomic alfalfa DNA. We found that the AL-A gene was highly homologous (90%) to the sequences from the pea plastocyanin via multiple alignments, and the deduced protein precursor was predicted to be chloroplast-specific via the ChloroP computer program. The protein was named alfalfa-plastocyanin (AL-P). It was characterized as being a light-inducible protein, and RT-PCR analysis showed that AL-P mRNA transcription only occurred in the leaves of the alfalfa plant and the alfalfa seedlings growth in lighted conditions. PCR was also used to amplify the DNA fragment encoding the AL-P promoter (AL-Pp) from genomic alfalfa DNA. PlantCARE analysis of the promoter sequence indicated that both a typical TATA box and a CAAT box were located in the promoter sequence, and some of the cis-elements that are responsible for light responsiveness were also identified within this promoter region. The AL-P gene promoter fused to the β-glucuronidase (GUS) reporter gene has been examined for expression in transgenic alfalfa seedlings. Our findings have a potential application in plant genetic engineering; the AL-Pp may be used to drive the expression of heterologous genes in transgenic alfalfa plants.
- Published
- 2013
12. Effects of Exogenous Calcium on Some Postharvest Characteristics of Cut Gladiolus
- Author
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Ji-gang Bai, Pei-lei Xu, Cheng-shun Zong, and Cai-yun Wang
- Subjects
biology ,Vase life ,fungi ,food and beverages ,chemistry.chemical_element ,Plant Science ,Cut flowers ,Calcium ,biology.organism_classification ,EGTA ,chemistry.chemical_compound ,Horticulture ,chemistry ,Botany ,Postharvest ,Zeatin ,Gladiolus ,Agronomy and Crop Science ,Abscisic acid - Abstract
In order to apply calcium to the vase solutions of cut gladiolus (Gladiolus hybridus), the vase life and some physiological characteristics were studied in this article. A gladiolus cultivar, Mascagni, was chosen for experiments, and its cut flowers were held into solutions, which contained calcium acetate, ethylene glycol bis-amino tetmacetate (EGTA), and water, respectively. The effects of calcium were probed by measuring the ornamental quality of cut gladiolus and the physiological characteristics such as calmodulin (CaM), abscisic acid (ABA), gibberellins (GA), zeatin (ZRs), endogenous calcium, malondialdehyde (MDA), and soluble sugar in florets. In a solution of 2 mmol L−1 calcium acetate, the opening rate of cut gladiolus was higher than that of control, and the vase life and ornamental value of flowers were better than that in control and other treatments of calcium acetate. Thus, the solution of 2 mmol L−1 calcium acetate has the best effect on the fresh keeping of cut gladiolus. In petals and bracts of cut gladiolus, the contents of CaM and GA and the ratios of GA/ABA and ZRs/ABA were higher in treatment of 2 mmol L−1 calcium acetate than that in control, while the contents of ABA and MDA were lower. Compared with the control, the solution of 2 mmol L−1 calcium acetate increased the endogenous calcium contents, and decreased the MDA contents, and alleviated the effects of EGTA on CaM, GA, GA/ABA, and ZRs/ABA. It made the soluble sugar content higher in petals than the control, but lower in bracts. Thus, the solution of 2 mmol L−1 calcium acetate not only stabilizes the membrane structure of cut gladiolus, but also activates CaM. It thereby controls the endogenous hormone levels, and transports soluble sugar into petals, and increases the vase life of the flower.
- Published
- 2009
13. Theoretical studies on the electronic structures and absorption spectra of substituted benzenes with one- and two-dimensional charge transfer character
- Author
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Hong-Tao Wang, Cai-Yun Wang, Haipeng Li, Kui Han, Xiaopeng Shen, and Gang Tang
- Subjects
Dipole ,Absorption spectroscopy ,Chemistry ,Transition dipole moment ,Ab initio ,Molecule ,Electronic structure ,Physical and Theoretical Chemistry ,Atomic physics ,Absorption (chemistry) ,Condensed Matter Physics ,Ground state ,Biochemistry - Abstract
The electronic structures and absorption spectra of one- and two-dimensional charge transfer (CT) molecules based on para-nitroaniline (pNA) and 1,3-diamino-4,6-dinitro- benzene (DADB) have been studied theoretically via semi-empirical and ab initio methods. It is found that the behaviors of optical absorption are strongly influenced by the dimension of CT. Different from the well-known one-dimensional CT molecule of pNA, which shows one intense absorption related to the π → π* CT transition, two-dimensional CT molecule of DADB exhibits more absorption peaks associated with various low-lying CT transitions in near ultraviolet range. In addition, the relative orientations of transition dipole moment and ground state dipole moment in one- and two-dimensional charge transfer molecules were also discussed.
- Published
- 2008
14. Partial hydrogenation of adiponitrile to 6-aminocapronitrile over Ni/α-Al2O3 catalyst promoted with K2O and La2O3
- Author
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Lei Zhao, Jiyan Zhang, Ji Xiang Chen, and Cai Yun Wang
- Subjects
Partial hydrogenation ,Ammonia ,chemistry.chemical_compound ,Nickel ,Chemistry ,Inorganic chemistry ,chemistry.chemical_element ,Nickel catalyst ,General Chemistry ,Adiponitrile ,Selectivity ,Potassium oxide ,Catalysis - Abstract
A novel K2O and La2O3 promoted nickel catalyst supported on α-Al2O3 was prepared by co-impregnation method, and it exhibited higher activity and 6-aminocapronitrile selectivity than Ni/α-Al2O3 during the hydrogenation of adiponitrile in the absence of ammonia, i.e., K2O and La2O3 improved the performance of the nickel-based catalyst.
- Published
- 2007
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