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13 results on '"Bulens, Paul"'

1. Response to the Comment on “Photobiomodulation therapy for the prevention of acute radiation dermatitis (RD) in head and neck cancer patients (DERMISHEAD trial)” by He et al.

Author

Robijns, Jolien, primary, Lodewijckx, Joy, additional, Claes, Stefan, additional, Van Bever, Leen, additional, Pannekoeke, Luc, additional, Censabella, Sandrine, additional, Bussé, Lore, additional, Colson, Dora, additional, Kaminski, Iris, additional, Broux, Victoria, additional, Puts, Sofie, additional, Vanmechelen, Sofie, additional, Timmermans, An, additional, Noé, Leen, additional, Bulens, Paul, additional, Govers, Mieke, additional, Maes, Annelies, additional, and Mebis, Jeroen, additional

Published
2022
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2. Response to the Comment on “Photobiomodulation therapy for the prevention of acute radiation dermatitis (RD) in head and neck cancer patients (DERMISHEAD trial)” by Baiocchi et al

Author

Robijns, Jolien, primary, Lodewijckx, Joy, additional, Claes, Stefan, additional, Van Bever, Leen, additional, Pannekoeke, Luc, additional, Censabella, Sandrine, additional, Bussé, Lore, additional, Colson, Dora, additional, Kaminski, Iris, additional, Broux, Victoria, additional, Puts, Sofie, additional, Vanmechelen, Sofie, additional, Timmermans, An, additional, Noé, Leen, additional, Bulens, Paul, additional, Govers, Mieke, additional, Maes, Annelies, additional, and Mebis, Jeroen, additional

Published
2021
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3. Response to the Letter to the editor by Donnelly et al. regarding the article “Photobiomodulation therapy for the prevention of acute radiation dermatitis in head and neck cancer patients (DERMISHEAD trial)”

Author

Robijns, Jolien, primary, Lodewijckx, Joy, additional, Claes, Stefan, additional, Van Bever, Leen, additional, Pannekoeke, Luc, additional, Censabella, Sandrine, additional, Bussé, Lore, additional, Colson, Dora, additional, Kaminski, Iris, additional, Broux, Victoria, additional, Puts, Sofie, additional, Vanmechelen, Sofie, additional, Timmermans, An, additional, Noé, Leen, additional, Bulens, Paul, additional, Govers, Mieke, additional, Maes, Annelies, additional, and Mebis, Jeroen, additional

Published
2021
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4. Photobiomodulation therapy for the prevention of acute radiation dermatitis in head and neck cancer patients (DERMISHEAD trial)

Author

Robijns, Jolien, primary, Lodewijckx, Joy, additional, Claes, Stefan, additional, Van Bever, Leen, additional, Pannekoeke, Luc, additional, Censabella, Sandrine, additional, Bussé, Lore, additional, Colson, Dora, additional, Kaminski, Iris, additional, Broux, Victoria, additional, Puts, Sofie, additional, Vanmechelen, Sofie, additional, Timmermans, An, additional, Noé, Leen, additional, Bulens, Paul, additional, Govers, Mieke, additional, Maes, Annelies, additional, and Mebis, Jeroen, additional

Published
2021
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6. Infrastructure and distributed learning methodology for privacy-preserving multi-centric rapid learning health care: euroCAT

Author

Deist, Timo M., primary, Jochems, A., additional, van Soest, Johan, additional, Nalbantov, Georgi, additional, Oberije, Cary, additional, Walsh, Seán, additional, Eble, Michael, additional, Bulens, Paul, additional, Coucke, Philippe, additional, Dries, Wim, additional, Dekker, Andre, additional, and Lambin, Philippe, additional

Published
2017
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8. Outcome after PORT in ypN2 or R1/R2 versus no PORT in ypN0 Stage III-N2 NSCLC after Induction Chemotherapy and Resection

Author

Billiet, Charlotte, primary, Peeters, Stéphanie, additional, Decaluwé, Herbert, additional, Vansteenkiste, Johan, additional, Dooms, Christophe, additional, Deroose, Christophe M., additional, Hendrikx, Marc, additional, De Leyn, Paul, additional, Bulens, Paul, additional, Karim, Rezaul, additional, Le Péchoux, Cécile, additional, Mebis, Jeroen, additional, and De Ruysscher, Dirk, additional

Published
2016
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9. Patterns of Locoregional Relapses in Patients with Contemporarily Staged Stage III-N2 NSCLC Treated with Induction Chemotherapy and Resection: Implications for Postoperative Radiotherapy Target Volumes

Author

Billiet, Charlotte, primary, De Ruysscher, Dirk, additional, Peeters, Stéphanie, additional, Decaluwé, Herbert, additional, Vansteenkiste, Johan, additional, Dooms, Christophe, additional, Deroose, Christophe M., additional, De Leyn, Paul, additional, Hendrikx, Marc, additional, Bulens, Paul, additional, Le Péchoux, Cécile, additional, and Mebis, Jeroen, additional

Published
2016
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12. Photobiomodulation therapy for the prevention of acute radiation dermatitis in head and neck cancer patients (DERMISHEAD trial)

Author

Stefan Claes, Lore Bussé, Annelies Maes, An Timmermans, Leen Van Bever, Mieke Govers, Jolien Robijns, Sofie Vanmechelen, Dora Colson, Leen Noé, Paul Bulens, Iris Kaminski, Luc Pannekoeke, Sofie Puts, Joy Lodewijckx, Sandrine Censabella, Victoria Broux, Jeroen Mebis, ROBIJNS, Jolien, LODEWIJCKX, Joy, Claes, Stefan, Van Bever, Leen, Pannekoeke, Luc, Censabella, Sandrine, Bussé, Lore, Colson, Dora, Kaminski, Iris, Broux, Victoria, Puts, Sofie, Vanmechelen, Sofie, Timmermans, An, Noé, Leen, BULENS, Paul, Govers, Mieke, MAES, Annelies, and MEBIS, Jeroen

Subjects
medicine.medical_specialty, Supportive cancer care, medicine.medical_treatment, Placebo, 030218 nuclear medicine & medical imaging, law.invention, 03 medical and health sciences, 0302 clinical medicine, Quality of life, Randomized controlled trial, law, Internal medicine, Medicine, Radiology, Nuclear Medicine and imaging, Head and neck cancer, Adverse effect, business.industry, Cancer, Hematology, Photobiomodulation, medicine.disease, Radiation therapy, Oncology, 030220 oncology & carcinogenesis, Concomitant, Radiodermatitis, business
Abstract

Background and purpose The purpose of this study was to investigate the effectiveness of photobiomodulation therapy (PBMT) for the prevention of acute radiation dermatitis (ARD) in head and neck cancer (HNC) patients. Materials and methods A randomised, placebo-controlled trial (RCT) with 46 HNC patients who underwent radiotherapy (RT) with or without concomitant chemotherapy was set up (DERMISHEAD trial). Patients were randomised to receive PBM or placebo treatments from the first day of RT (2×/week) alongside the institutional skincare. The severity of skin reactions was assessed by the National Cancer Institute-Common Terminology Criteria for Adverse Events version 4.03 (NCI-CTCAE v4.03) and the Radiotherapy-Induced Skin Reaction Assessment Scale (RISRAS). Quality of life (QoL) was evaluated using the Skindex-16 questionnaire. Results PBMT significantly reduced NCI-CTCAE grade 2–3 ARD with 49% at the end of RT. Conclusion The results of the first RCT in HNC patients showed that PBMT is an effective method to prevent the development of severe ARD. These results support the implementation of PBM in the clinical oncology – radiotherapy practice. This research is part of the Limburg Clinical Research Center (LCRC) UHasselt-ZOL-Jessa, financially supported by the foundation Limburg Sterk Merk, province of Limburg, Flemish Government, Hasselt University, Ziekenhuis Oost-Limburg, and Jessa Hospital. Additionally, this research project is funded by Kom op tegen Kanker (Stand up to Cancer), the Flemish Cancer Society, Limburgs Kankerfonds, and ASA Srl.

Published
2021

13. Photobiomodulation for the prevention of radiodermatitis: Preliminary results of a randomized controlled clinical trial in breast cancer patients

Author

Ivo Lambrichts, Paul Bulens, Lore Bussé, An Timmermans, Jolien Robijns, Niels Hellings, Stefan Claes, Veerle Somers, Jeroen Mebis, Sandrine Censabella, Annelies Maes, ROBIJNS, Jolien, Censabella, Sandrine, Claes, Stefan, Bussé, Lore, HELLINGS, Niels, LAMBRICHTS, Ivo, Timmermans, An, MAES, Annelies, BULENS, Paul, SOMERS, Veerle, and MEBIS, Jeroen

Subjects
medicine.medical_specialty, business.industry, Alternative medicine, Hematology, medicine.disease, Radiation dermatitis, laser therapy, photobiomodulation therapy, breast cancer, radiotherapy, language.human_language, Clinical trial, Flemish, Breast cancer, Oncology, Internal medicine, Physical therapy, language, Medicine, Radiodermatitis, business
Abstract

Background: The aim of our study was to investigate the efficacy of photobiomodulation therapy (PBMT) for the prevention of radiodermatitis (RD) in breast cancer patients. Methods: This is a randomized controlled, patient-blinded study with breast cancer patients that underwent an identical radiotherapy (RT) regime post-lumpectomy. A total of 57 patients were enrolled and randomly assigned to the intervention group to receive laser therapy (LT, n = 30) or the control group to receive a sham treatment (n = 27). LT or sham was applied two days a week, immediately after the RT session, starting at the first day of RT. LT was delivered using a class IV MLS® laser that combines two synchronized laser diodes in the infrared range (808-905 nm) with a fixed energy density (4 J/cm2). There were no significant differences between the two groups with respect to patient- and treatment-related characteristics. The skin reactions were evaluated by trained, blinded nurses at fraction 20 and at the end of RT (fraction 33) according to the criteria of the Radiation Therapy Oncology Group (RTOG). Results: At fraction 20 of RT the distribution of the RTOG grades was comparable between both groups ( p= .238), with most of the patients presenting RTOG grade 1. At the end of RT, the severity of RD significantly differed between the two groups ( p= .035), with a greater proportion of patients experiencing RD grade 2 or higher in the control group (30% vs. 7%, for the control and LT group, resp.). The skin reactions of the patients in the control group aggravated ( p= .006), while they remained stable in the LT group ( p= .205).Conclusions: In the control group the skin reactions developed into more severe forms (e.g. moist desquamation) towards the end of RT, whereas in the LT group the skin reactions remained stable. Results of this study show that PBMT is able to prevent aggravation of acute skin reactions of breast cancer patients undergoing RT. Hasselt University, Limburg Sterk Merk, Province of Limburg, Jessa Hospital, Flemish Government, Limburgs Kankerfonds, ASA srl

Published
2016

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