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17 results on '"Brambilla, Daniela"'

1. NDP-MSH treatment recovers marginal lungs during ex vivo lung perfusion (EVLP)

Author

Lonati, Caterina, primary, Battistin, Michele, additional, Dondossola, Daniele E., additional, Bassani, Giulia A., additional, Brambilla, Daniela, additional, Merighi, Riccardo, additional, Leonardi, Patrizia, additional, Carlin, Andrea, additional, Meroni, Marica, additional, Zanella, Alberto, additional, Catania, Anna, additional, and Gatti, Stefano, additional

Published
2021
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3. Mesenchymal stem cell–derived extracellular vesicles improve the molecular phenotype of isolated rat lungs during ischemia/reperfusion injury

Author

Lonati, Caterina, primary, Bassani, Giulia Alessandra, additional, Brambilla, Daniela, additional, Leonardi, Patrizia, additional, Carlin, Andrea, additional, Maggioni, Marco, additional, Zanella, Alberto, additional, Dondossola, Daniele, additional, Fonsato, Valentina, additional, Grange, Cristina, additional, Camussi, Giovanni, additional, and Gatti, Stefano, additional

Published
2019
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4. Pneumonectomy in Stage IIIA-N2 NSCLC: Should It Be Considered After Neoadjuvant Chemotherapy?

Author

Casiraghi, Monica, primary, Guarize, Juliana, additional, Sandri, Alberto, additional, Maisonneuve, Patrick, additional, Brambilla, Daniela, additional, Romano, Rosalia, additional, Galetta, Domenico, additional, Petrella, Francesco, additional, Gasparri, Roberto, additional, Gridelli, Cesare, additional, De Marinis, Filippo, additional, and Spaggiari, Lorenzo, additional

Published
2019
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9. The Role of Extended Pulmonary Metastasectomy

Author

Casiraghi, Monica, primary, Maisonneuve, Patrick, additional, Brambilla, Daniela, additional, Petrella, Francesco, additional, Solli, Piergiorgio, additional, Guarize, Juliana, additional, De Marinis, Filippo, additional, and Spaggiari, Lorenzo, additional

Published
2015
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10. Extrapleural Pneumonectomy for Malignant Mesothelioma: An Italian Multicenter Retrospective Study

Author

Spaggiari, Lorenzo, primary, Marulli, Giuseppe, additional, Bovolato, Pietro, additional, Alloisio, Marco, additional, Pagan, Vittore, additional, Oliaro, Alberto, additional, Ratto, Giovanni Battista, additional, Facciolo, Francesco, additional, Sacco, Rocco, additional, Brambilla, Daniela, additional, Maisonneuve, Patrick, additional, Mucilli, Felice, additional, Alessandrini, Gabriele, additional, Leoncini, Giacomo, additional, Ruffini, Enrico, additional, Fontana, Paolo, additional, Infante, Maurizio, additional, Pariscenti, Gian Luca, additional, Casiraghi, Monica, additional, and Rea, Federico, additional

Published
2014
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11. Features and Prognostic Factors of Large Node-Negative Non–Small-Cell Lung Cancers Shifted to Stage II

Author

Toffalorio, Francesca, primary, Radice, Davide, additional, Spaggiari, Lorenzo, additional, Sinno, Valentina, additional, Barberis, Massimo, additional, Spitaleri, Gianluca, additional, Giovannini, Monica, additional, Delmonte, Angelo, additional, Catania, Chiara, additional, Noberasco, Cristina, additional, Brambilla, Daniela, additional, de Braud, Filippo, additional, Veronesi, Giulia, additional, Solli, Piergiorgio, additional, and De Pas, Tommaso, additional

Published
2012
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13. A 10-Year Single-Center Experience on 708 Lung Metastasectomies: The Evidence of the “International Registry of Lung Metastases”

Author

Casiraghi, Monica, primary, De Pas, Tommaso, additional, Maisonneuve, Patrick, additional, Brambilla, Daniela, additional, Ciprandi, Barbara, additional, Galetta, Domenico, additional, Borri, Alessandro, additional, Gasparri, Roberto, additional, Petrella, Francesco, additional, Tessitore, Adele, additional, Guarize, Juliana, additional, Donghi, Stefano Maria, additional, Veronesi, Giulia, additional, Solli, Piergiorgio, additional, and Spaggiari, Lorenzo, additional

Published
2011
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14. Screening-Detected Lung Cancers: Is Systematic Nodal Dissection Always Essential?

Author

Veronesi, Giulia, primary, Maisonneuve, Patrick, additional, Pelosi, Giuseppe, additional, Casiraghi, Monica, additional, Agoglia, Bernardo G., additional, Borri, Alessandro, additional, Travaini, Laura L., additional, Bellomi, Massimo, additional, Rampinelli, Cristiano, additional, Brambilla, Daniela, additional, Bertolotti, Raffaella, additional, and Spaggiari, Lorenzo, additional

Published
2011
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17. Pneumonectomy in Stage IIIA-N2 NSCLC: Should It Be Considered After Neoadjuvant Chemotherapy?

Author

Patrick Maisonneuve, Roberto Gasparri, Domenico Galetta, Monica Casiraghi, Lorenzo Spaggiari, Filippo de Marinis, Cesare Gridelli, Rosalia Romano, Daniela Brambilla, Alberto Sandri, Francesco Petrella, Juliana Guarize, Casiraghi, Monica, Guarize, Juliana, Sandri, Alberto, Maisonneuve, Patrick, Brambilla, Daniela, Romano, Rosalia, Galetta, Domenico, Petrella, Francesco, Gasparri, Roberto, Gridelli, Cesare, De Marinis, Filippo, and Spaggiari, Lorenzo

Subjects
Male, 0301 basic medicine, Pulmonary and Respiratory Medicine, Cancer Research, medicine.medical_specialty, Lung Neoplasms, medicine.medical_treatment, Bronchopleural fistula, Induction therapy, Gastroenterology, 03 medical and health sciences, Pneumonectomy, Postoperative Complications, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Internal medicine, medicine, Humans, Stage (cooking), Lung cancer, Aged, Neoplasm Staging, Retrospective Studies, Chemotherapy, Advanced stage, business.industry, Incidence (epidemiology), Mortality rate, Middle Aged, Short and long term outcome, medicine.disease, Survival Analysis, Occult, Neoadjuvant Therapy, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Female, Surgery, Tomography, X-Ray Computed, business, Follow-Up Studies
Abstract

Background: Owing to the expected poor long-term outcomes and high postoperative morbidity and mortality, patients with stage IIIA-N2 tumors candidate to pneumonectomy (PN) are usually excluded from surgery. This study aims to analyze the outcome of patients who underwent PN to prove its safety and feasibility. Patients and Methods: We retrospectively analyzed data from 233 patients who underwent PN for N2 non–small-cell lung cancer (NSCLC) between 1998 and 2015. Eighty-five patients were occult N2 disease (group 1), whereas 148 patients underwent induction therapy (IT) for stage IIIA-N2 (group 2). Results: Overall morbidity, postoperative mortality, and 90-day mortality rates were 46.8%, 2.6%, and 8.6%, respectively. The 2 groups (group 1 vs. 2) had similar postoperative and 90-day mortality rates: 2.4% versus 2.7% (P = 1.00), and 9.4% versus 8.1% (P =.81), respectively. The incidence of major morbidity was higher and statistically significant in group 2 compared with group 1: 23% versus 12.9% (P =.1). Postoperative bronchopleural fistula occurred in 4.7% (4/85) of patients with occult N2 (group 1) and in 10.1% (15/148) of patients undergoing IT (group 2) (P = .10). Median overall survival (OS) was 2.2 years, with a 3 and 5-year OS of 43.4% and 31.6%, respectively. Disease-free survival (DFS) was 1.5 years, with 3 and 5-year DFS of 41.6% and 32%, respectively; no difference in OS and DFS between the 2 groups was found. Conclusions: Considering the acceptable morbidity and mortality rate and the long-term survival, PN should not be excluded for selected patients with stage IIIA-N2 NSCLC as a matter of principle. This study aims to analyze the outcome of patients with stage IIIA-N2 non–small-cell lung cancer who underwent pneumonectomy to prove its safety and feasibility, in particular after induction chemotherapy. Based on the acceptable morbidity and mortality rate and the long-term survival, pneumonectomy should not be excluded for selected patients as a matter of principle.

Published
2019
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