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755 results on '"Bourgoin, A."'

6. Minor and trace element concentrations in roe deer hair: A non-invasive method to define reference values in wildlife

Author

Herrada, Amandine, primary, Bariod, Léa, additional, Saïd, Sonia, additional, Rey, Benjamin, additional, Bidault, Hervé, additional, Bollet, Yoann, additional, Chabot, Stéphane, additional, Débias, François, additional, Duhayer, Jeanne, additional, Pardonnet, Sylvia, additional, Pellerin, Maryline, additional, Fanjul, Jean-Baptiste, additional, Rousset, Cyril, additional, Fritsch, Clémentine, additional, Crini, Nadia, additional, Scheifler, Renaud, additional, Bourgoin, Gilles, additional, and Vuarin, Pauline, additional

Published
2024
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7. A Streamlined Approach to Basophil Activation Testing for Longitudinal Characterization of Toddlers with Peanut Allergy During a Multi-Site Phase 3 Double-Blind Placebo-Controlled Trial of Epicutaneous Immunotherapy (EPIT)

Author

Grishin, Alexander, primary, Arif-Lusson, Rihane, additional, Bourgoin, Penelope, additional, Matthews, Katie, additional, Campbell, Dianne, additional, Bahnson, Henry, additional, Busnel, Jean-Marc, additional, and Sampson, Hugh, additional

Published
2024
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11. Red Blood Cell Transfusion Requirements Before and After Implementation of a Perioperative Patient Blood Management Program in Adult Patients Undergoing Cardiac Surgery. A Before and After Observational Study

Author

Czarnecka, Jeremie, primary, Neuschwander, Arthur, additional, Aujoulat, Thomas, additional, Balmier, Adrien, additional, Belcour, Dominique, additional, Boulanger, Boris, additional, Bourgain, Caroline, additional, Caron, Margot, additional, Kiss, Gabor, additional, Larghi, Mathilde, additional, Lebard, Christophe, additional, Mellano, Vincent, additional, Larson, Jonathan, additional, Megroian, Blandine, additional, Lefrançois, Anaelle, additional, Fox, Sylvain, additional, Pollet, Arnaud, additional, Bourgoin, Pierre, additional, Biland, Guillaume, additional, Braunberger, Eric, additional, Maccio, Guillaume, additional, and Delmas, Benjamin, additional

Published
2023
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15. Prediction of response to immune checkpoint blockade in patients with metastatic colorectal cancer with microsatellite instability

Author

Ratovomanana, T., primary, Nicolle, R., additional, Cohen, R., additional, Diehl, A., additional, Siret, A., additional, Letourneur, Q., additional, Buhard, O., additional, Perrier, A., additional, Guillerm, E., additional, Coulet, F., additional, Cervera, P., additional, Benusiglio, P., additional, Labrèche, K., additional, Colle, R., additional, Collura, A., additional, Despras, E., additional, Le Rouzic, P., additional, Renaud, F., additional, Cros, J., additional, Alentorn, A., additional, Touat, M., additional, Ayadi, M., additional, Bourgoin, P., additional, Prunier, C., additional, Tournigand, C., additional, Fouchardière, C. de la, additional, Tougeron, D., additional, Jonchère, V., additional, Bennouna, J., additional, de Reynies, A., additional, Fléjou, J.-F., additional, Svrcek, M., additional, André, T., additional, and Duval, A., additional

Published
2023
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26. Sarilumab in adults hospitalised with moderate-to-severe COVID-19 pneumonia (CORIMUNO-SARI-1): An open-label randomised controlled trial

Author

Anatole Harrois, Florence Patin, Anaïs Razurel, Laure Allanic, Grégoire Martin de Frémont, Vincent Jachiet, Gonçalo Boleto, Eric D'Ortenzio, Xavier Mariette, Philippe Dieudé, Etienne Canouï, Z Julia, Nathalie Dournon, Jean-Sébastien Hulot, David Lebeaux, Eric Mariotte, Dorothee Vallois, Laurence Berard, Nicolas Gambier, Christiane Verny, Mathilde Le Marchand, Mitja Jevnikar, Jean-Jacques Mourad, Marjolaine Morgand, Bertrand Guidet, Alexandre Moores, Prissile Bakouboula, Frédéric Pène, Pascal Richette, Martine Meunier, Juliette Camuset, Stéphane Jauréguiberry, Lynda Chalal, Mamadou Salif Cisse, Marie-Hélène Legros, Yann Nguyen, Damien Roux, Robin Deleris, Maxence Decavele, Patrice Cacoub, Isabelle Dusanter, Patricia Senet, Nassim Mahtal, Raphael Borie, Philippe Benoit, Blandine Denis, Luca Semerano, Sebastien Abad, Marie Dubert, Marie Lachatre, Marine Livrozet, Nathan Ebstein, Lakhdar Mameri, Adrien Michon, Olivier Sanchez, Aurélien Guffroy, Pierre Dupland, Jérôme Pacanowski, Yasmina Ferfar, Tassadit Hadjam, Anne-Marie Roques, Celine Comparon, Solaya Chalal, A Soria, Isabelle Lehir, Anne Gysembergh-Houal, Stéphanie Alary, Valérie Dejean, Elena Kiouris, Estelle Henry, Sophie Diemunsch, Jonathan London, Fanny Charbonnier, Alexandre Demoule, Louise Bondeelle, Samira Saleh-Mghir, Lise Bernard, Brigitte Sabatier, Anne Jacolot, Aurelie Sautereau, Pierre Faye, Benjamin Fournier, Noémie Abisror, Awa Ndiaye, Ruben Benainous, Damien Sène, Emmanuelle Sacco, Isabelle Debrix, Gabriel Nisand, Régis Peffault de Latour, Anne Sophie Korganow, Kévin Cardet, Perrine Guillaume-Jugnot, Soumeya Hammal, B. Duchemann, Elena Fois, Jean-Benoit Arlet, Christine Broissand, Yaël Amara, Matheus Vieira, Sophie Caillat-Zucman, Madona Sakkal, Juliette Djadi-Prat, Jean-Louis Teboul, Hélène François, Stéphane Renaud, Sylviane Ravato, Alaki Thiemele, Gabrielle Archer, Alain Fourreau, David Boutboul, Arsène Mekinian, Antoine Gros, Morgane Faure, Anne Pattyn, Camille Petit-Hoang, Jessica Krause le Garrec, Antony Canellas, Jean-Michel Molina, Zakaria Ait Hamou, Eric Oksenhendler, Ilias Koumis, Marie-Aude Penet, Catherine Boussard, Vincent Fallet, Guillaume Geri, Loic Kassegne, Bernard Cholley, Lucie Biard, Elodie Perrodeau, Tomas Urbina, David Schmitz, johann Cailhol, Elise Morawiec, Audrey Phibel, Sophie Renet, Emmanuel Weiss, Faouzi Saliba, Kristina Beziriganyan, Abdellatif Tazi, Isabelle Peigney, Bertrand Dunogue, Rémy Gauzit, Damien Bergerot, Bob Heger, Ines Ben-Mabrouk, Jade Ghosn, Benjamin Planquette, Alexis Régent, François Weill, Yasmina Mekid, Rosa Da Silva, Victor Lancon, Marc Michel, Nadia Anguel, Anne Claire Desbois, François Danion, Brigitte Ranque, Mohamed Belloul, Nadège Lemarié, Amélie Cransac, Marine Nadal, Lalia Djaghout, Anne Tréhan, Samy Figueiredo, Hakim Meddah, Aurélie Clan Hew Wai, Julie Delemazure, Soraya Fellahi, Jacques-Eric Gottenberg, Matthieu Uzzan, Jean-Charles Duclos-Vallée, Tabassome Simon, Vanessa Rathouin, Yves Hansmann, Hélène Gros, Syllia Belazouz, Nathalie Marin, Camille Rolland-Debord, Edouard Lefèvre, Sophie-Rym Hamada, Tristan Martin, Annabelle Stoclin, Frédéric Duée, Helene Chambrin-Lauvray, Ramdane Meftali, Miguel Alejandro Vasquez-Ibarra, Isabelle Madeleine, Simon Valayer, Anne Adda, Marie-Thérèse Tremorin, Nicolas Meyer, Vixra Keo, Lara Zafrani, Caroline Semaille, Maxime Dougados, Olivier Olivier, Emeline Colomba, Florence Morin, Claire Rouzaud, Paul Michel Mertes, Claire Montlahuc, Anne Blanchard, Valérie Pourchet-Martinez, Constance Delaugerre, Nicolas Carlier, Jacques Cadranel, Nicolas Noel, Kahina Cheref, Bao Phung, Moez Jallouli, Ulrich Clarac, Marthe Rigal, Mireille Adda, Lionel Galicier, Fanny Domont, Lee S. Nguyen, Férial Berbour, Fanny Pommeret, Celine Dupré, Gaël Leprun, Jean-Luc Diehl, Laetitia Languille, Philippe Blanche, Abolfazl Mohebbi, Mathilde Noaillon, Olivier Collange, Paul Jaubert, Anne Daguenel-Nguyen, Sandrine Briois, Anne-Lise Pouliquen, Coralie Bloch Queyrat, Clément Jourdaine, Cédric Pierron, Geoffrey Rossi, Chloe McAvoy, Claire Courtin, Mathias Cornic, C Rioux, Christine Lemagner, Martin Dres, Emmanuelle Guillot, Marc Garnier, Safaa Nemlaghi, Guillaume Grailles, Yazdan Yazdanpanah, Veronique Joly, Thiziri Sadaoui, Marion Bouhris, Vincent Castelain, Muriel Fartoukh, Sébastien Cavelot, Sophie Ohlmann-Caillard, Valentina Isernia, Bruno Crestani, Thinhinane Bariz, Benjamin Chaigne, Emmanuel Andrès, Frédéric Blanc, Alain Wynckel, Louise-Laure Mariani, Yasmine Messaoudi, Naima Sguiouar, Amina Kebir, Asmaa Mamoune, Caroline Gaudefroy, Victoire De Lastours, Pierre Diemunsch, Etienne Lengliné, Claire Tantet, Julien Mayaux, Benjamin G. Chousterman, Arthur Pavot, Anne Rachline, Gwenaël Lorillon, Hassan Joumaa, Nicolas Lefebvre, Elodie Baudry, Nicolas Bonnet, Fanny Defrancq, Véronique Vigna, Yves Cohen, Amira Benattia, Martin Siguier, Sophie Georgin-Lavialle, Emmanuelle Bugnet, Lamiae Grimaldi, Olivia Daconceicao, Olivier Hermine, Mathieu Vautier, Florence Tubach, Marion Licois, Anaïs Codorniu, Fanny Alby-Laurent, Jérémie Zerbit, Aude Jacob, Benedicte Giroux-Leprieur, Carine Karachi, Laurent Cylly, Edouard Flamarion, Gladys Aratus, Charléne Jouve, Robin Dhote, Claire Davoine, Valentin Greigert, Gaelle Leroux, Cécile Kedzia, Guillaume Lefèvre, Catherine Metzger, Olivier Benveniste, Clairelyne Dupin, Marie-Alexandra Alyanakian, Mathieu Oberlin, Julien Poissy, Linda Gimeno, Adrien Contejean, Segolene Toquet, Jeanne CHAUFFiER, Mathieu Jozwiak, Laurent Savale, Virginie Zarrouk, Cécile Yelnik, Mandy Nizard, Mourad Djadel, F-Xavier Lescure, Agnes Maurer, Geoffroy Liégeon, Arthur Neuschwander, Hélène Lafoeste, Gaëtan Deslée, Frédéric De Blay, Claire Pernin, Cloé Comarmond, Anne Hutt, Ridha Belilita, Laurence Lecomte, Sophie-Caroline Sacleux, Nathalie Rozensztajn, Jean-Jacques Tudesq, Benjamin Terrier, Solène Fabre, Lelia Escaut, Eva Chatron, Emmanuelle Blin, Pauline Jouany, Sara Sambin, Chistophe Willekens, Nabil Raked, Jean-Simon Rech, Serge Bureau, Boris Bienvenu, Elisabeth Coupez, Tali-Anne Szwebel, Lydia Suarez, Chaouki Bouras, Kamyl Baghli, Emilia Stan, Valérie Camara-Clayette, Fanette Denies, Nathalie Menage, Paul Legendre, Axelle Fuentes, Oriane Puéchal, Charlotte Kaeuffer, Guillaume Becker, Clara Campos-Vega, Armand Mekontso-Dessaps, Pernelle Vauboin, Yurdagul Uzunhan, F Louni, Marie hélène Pari, Myriam Virlouvet, Nicolas Belaube, Hugues Cordel, Nathalie Chavarot, Olivier Sitbon, Jean-Daniel Lelievre, Matthieu Mahévas, Julie Smati, Olivier Clovet, Marc Bardou, Ada Clarke, Gilles Garcia, Anouk Walter-Petrich, Hala Semri, Vasco Honsel, Giovanna Melica, Pierre Mora, Olivier Fain, A Gervais, Marc Humbert, Yves Allenbach, Céline Verstuyft Verstuyft, Blandine Lehmann, Pascal Martel, Aida Zahrate-Ghoul, Karine Martin, Alexandre Bourgoin, Baptiste Duceau, Philippe Ravaud, Celine Wilpotte, Sylvie Le Gac, Michaël Darmont, Aurélie Durel Maurisse, Younes Keroumi, Aude Rigolet, Julie Chas, Pierre-Louis Tharaux, Caroline Morbieu, Valérie Paquet, Eric Vicaut, Pascaline Choinier, Samir Hamiria, Elsa Feredj, Frédéric Schlemmer, Gilles Pialoux, Zeina Louis, Marion Parisey, David Montani, Jean-Pierre Riveline, Jean-Marie Michot, Pascal Lim, Eliane Bertrand, Gaelle Clavere, Julie Jambon, Stéphane Brin, Saskia Flamand, Jeanne Meunier, Geoffroy Volle, Martin De Sarcus, Marie Vayssettes, Thomas Papo, Caroline Hauw-Berlemont, Gabriel Baron, Jeremy Arzoine, Loren Soyez-Herkert, Maria Pereira, Antoine Parrot, Johanna Oziel, Carole Burger, Eric Noll, Paul Vermes, Jeanne Goupil de Bouille, Xavier Monnet, Paul Crespin, Sarah Dalibey, Thierno Dieye, Renaud Felten, Jean-Philippe Bastard, Younes El Amine, Timothee Bironne, Damien Vanhoye, Amine Ghembaza, Laure Berton, Yvon Ruch, Thomas Volpe, Thomas Gorget, Jaouad Benhida, Julien Saussereau, Elodie Issorat, Virginie Elisee, Adrien Mirouse, Cecile Larcheveque, Laurène Deconinck, A. Dossier, Félix Ackermann, Greggory Ducrocq, Anne Bergeron, Laurence Annonay, Camille Knosp, Laurence Drouard, Adrien Joseph, Hilario Nunes, Hanane Fodil, Sabrine Ouamri, Belkacem Asselate, Julie Fillon, Dominique Dautel, Isabelle Brindele, Robin Charreteur, S Lariven, Elie Azoulay, Sami Kolta, Cédric Sublon, Florence Bellenfant, Melissa Clément, Lola-Jade Palmieri, Bruno Mourvillier, Ewa Kozaliewicz, Vincent Provitolo, Marie Lecronier, Julien Chabert, Matthieu Resche-Rigon, Stéphan Pavy, Naura Gamany, Dorothée Chopin, Aïcha Bah, Moustafa Benafla, Corinne Guerin, Pierre Tissieres, Nathalie Costedoat-Chalumeau, Nessima Yelles, Emmanuel Chatelus, Jean-Christophe Corvol, Luc Mouthon, Marie Gilbert, Matthieu Lemoine, Lucie Aunay, Candice Estellat, Laure Choupeaux, Dhiaa Meriem Hai, Bernard Goichot, Céline Louapre, Roza Rahli, Nathalie De Castro, Christian Richard, Malikhone Chansombat, Kamil Chitour, Joseph Emmerich, Elodie Drouet, Julien Pottecher, Eric Demonsant, Alexandra Beurton, Raphaël Porcher, Lauren Demerville, Amélie Servettaz, Annabelle Pourbaix, Philippe Manivet, Pierre-Grégoire Guinot, Nicolas Champtiaux, Caroline Pradon, Annick Tibi, Julien Le Marec, Nawal Derridj, Mohamad Zaidan, Eric Marquis, Mickael Henriques, Bruno Mégarbane, Aline Frazier, Ramon Junquera, Diane Le Pluart, Coralie Gernez, Yacine Boudali, Dimitri Fremont, Pierrick Le Borgne, Corinne Pernot, Mélanie Dehais, Claire Madelaine, Dominique Roulot, Georgina Maalouf, Constance Guillaud, Corine Nyanou, Karine Celli Lebras, Sophie Granville, Sabrina Brahmi, Catherine Le Bourlout, Hassan Tarhini, Asmaa Mabrouki, Hakim Tayebi, Sophie Ismael, Jonathan Marey, Sophie Bayer, Gabriel Steg, Antoine Fayol, Catherine Fauvaux, Delphine Feyeux, Côme Bureau, Alexandre Morel, Agathe Bounhiol, Alexandre Buffet, Souad Benarab, Luc Haudebourg, Pierre Le Guen, Damien Vimpere, Xavier Jaïs, Clotilde Le Tiec Le Tiec, Sophie Bulifon, Pélagie Thibaut, Alison Klasen, Claire Pacheco, Anne Godier, Marie Antignac, Domitille Molinari, Philippe Durand, Olivier Lambotte, Paul Henri Grisot, Anne Lise Jegu, Vincent Poindron, Ruxandra Burlacu, Denis Jesuthasan, Sarah Benghanem, Solen Kernéis, Antoine Bachelard, Jacques Duranteau, Karine Lacombe, Olivia Lenoir, Mathilde Vallet, Sara Virolle, Léa Resmini, Liem Binh Luong Nguyen, Marie Matignon, Céline Leplay, and Claire Aguilar

Subjects
medicine.medical_specialty, business.industry, Immunology, Hazard ratio, Absolute risk reduction, Articles, medicine.disease, law.invention, Clinical trial, Pneumonia, Sarilumab, Rheumatology, Randomized controlled trial, law, Internal medicine, Cohort, medicine, Immunology and Allergy, Adverse effect, business
Abstract

Summary Background Patients with COVID-19 pneumonia can have increased inflammation and elevated cytokines, including interleukin (IL)-6, which might be deleterious. Thus, sarilumab, a high-affinity anti-IL-6 receptor antibody, might improve the outcome of patients with moderate-to-severe COVID-19 pneumonia. Methods We did a multicentric, open-label, Bayesian randomised, adaptive, phase 2/3 clinical trial, nested within the CORIMUNO-19 cohort, to test a superiority hypothesis. Patients 18 years or older hospitalised with COVID-19 in six French centres, requiring at least 3L/min of oxygen but without ventilation assistance and a WHO Clinical Progression Scale [CPS] score of 5 were enrolled. Patients were randomly assigned (1:1) via a web-based system, according to a randomisation list stratified on centre and with blocks randomly selected among 2 and 4, to receive usual care plus 400 mg of sarilumab intravenously on day 1 and on day 3 if clinically indicated (sarilumab group) or usual care alone (usual care group). Primary outcomes were the proportion of patients with WHO-CPS scores greater than 5 on the 10-point scale on day 4 and survival without invasive or non-invasive ventilation at day 14. This completed trial is closed to new participants and is registered with ClinicalTrials.gov , NCT04324073 . Findings 165 patients were recruited from March 27 to April 6, 2020, and 148 patients were randomised (68 patients to the sarilumab group and 80 to the usual care group) and followed up for 90 days. Median age was 61·7 years [IQR 53·0–71·1] in the sarilumab group and 62·8 years [56·0–71·7] in the usual care group. In the sarilumab group 49 (72%) of 68 were men and in the usual care group 59 (78%) of 76 were men. Four patients in the usual care group withdrew consent and were not analysed. 18 (26%) of 68 patients in the sarilumab group had a WHO-CPS score greater than 5 at day 4 versus 20 (26%) of 76 in the usual care group (median posterior absolute risk difference 0·2%; 90% credible interval [CrI] −11·7 to 12·2), with a posterior probability of absolute risk difference greater than 0 of 48·9%. At day 14, 25 (37%) patients in the sarilumab and 26 (34%) patients in the usual care group needed ventilation or died, (median posterior hazard ratio [HR] 1·10; 90% CrI 0·69–1·74) with a posterior probability HR greater than 1 of 37·4%. Serious adverse events occurred in 27 (40%) patients in the sarilumab group and 28 (37%) patients in the usual care group (p=0·73). Interpretation Sarilumab treatment did not improve early outcomes in patients with moderate-to-severe COVID-19 pneumonia. Further studies are warranted to evaluate the effect of sarilumab on long-term survival. Funding Assistance publique—Hopitaux de Paris

Published
2022
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27. Use of Large-Eddy Simulation for the bed shear stress estimation over a dune

Author

Adrien Bourgoin, Riadh Ata, Jérôme Thiébot, and Sylvain Guillou

Subjects
Turbulence, business.industry, Stratigraphy, Flow (psychology), 0207 environmental engineering, Geology, 02 engineering and technology, Mechanics, 010501 environmental sciences, Computational fluid dynamics, 01 natural sciences, Free surface, Shear stress, 020701 environmental engineering, business, Reynolds-averaged Navier–Stokes equations, Sediment transport, 0105 earth and related environmental sciences, Large eddy simulation
Abstract

Environmental flows are generally characterized by complex bed morphology and high current speeds. Such configurations favor the formation of vortex structures that strongly affect hydrody-namics and sediment transport. Large-Eddy Simulation (LES) enables investigation of the dynam-ics of the largest turbulence scales and, thanks to enhanced calculation resources, has now become applicable for simulating environmental flows. In this paper, a LES approach is developed in a CFD code (TELEMAC-3D), which was originally developed to simulate free surface flows using RANS methods. The present developments involve implementing subgrid models, boundary con-ditions and numerical schemes suitable for LES. The LES version of TELEMAC-3D was validated by comparing results on the model with experimental data for flow past a cylinder. Then, the model was applied to a test case representing flow over dunes. After validating the hydrodynamics, the model was used to assess the bottom shear stress, using both a RANS and a LES approach. Com-parison highlighted the potential contribution of LES to investigating the hydrodynamic forces acting on the bottom.

Published
2021
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28. Morbidité et résultats radiocliniques précoces des arthrodèses antérieures lombaires par implant intervertébral en tantale

Author

Antoine Bourgoin, Pierre Kriegel, Patrick Chatellier, Jonathan Lebhar, Yann Breton, and Mickaël Ropars

Subjects
Orthopedics and Sports Medicine, Surgery
Abstract

Resume Objet L’objectif de cette etude etait d’evaluer la morbidite des arthrodeses lombaires par voie anterieure (ALIF) utilisant un implant intervertebral en tantale. Ce materiau metallique extremement poreux possede une osteointegration, une osteoinduction, une osteoconduction et une stabilite primaire superieure aux autres materiaux utilises plus habituellement (polyetherethercetone PEEK, titane). La morbidite perioperatoire, les resultats fonctionnels a court terme (2 ans) et l’impaction radiographique des implants ont egalement ete analyses. Methodes Cette etude retrospective monocentrique a porte sur 94 patients operes, entre 2014 et 2017, pour une discopathie degenerative (75 %), un spondylolisthesis degeneratif (3 %) ou un spondylolisthesis par lyse isthmique (22 %). Soixante-cinq patients (69 %) ont ete operes par ALIF isolee (« stand-alone »), 24 (26 %) avec association d’une osteosynthese anterieure et 5 (5 %) avec une osteosynthese posterieure associee. Une courbe de survie a ete etablie selon Kaplan–Meier avec, comme critere principal d’echec, la reprise chirurgicale. Les complications perioperatoires ont ete recensees. L’evaluation clinique au dernier recul utilisait une echelle visuelle analogique radiculaire (EVA-R), lombaire (EVA-L) et le score d’Oswestry Disability Index (ODI). Les impactions, evaluees sur les radiographies, ont ete reparties en 2 groupes en fonction de la severite afin d’etablir des facteurs de risques (FDR). Resultats L’objectif principal montre un taux de survie a 2 ans de 94 % (IC 95 % [0,88 ; 0,99]). Deux patients ont ete repris precocement pour une impaction et 4 patients tardivement pour une pseudarthrodese. Le taux de complications perioperatoire etait de 8,5 %, de cause essentiellement vasculaire. Au recul moyen de 33 mois (24–59), les resultats cliniques etaient significativement ameliores et le taux d’impaction etait de 36 % en postoperatoire immediat (POI) et de 47 % a un an. Conclusion L’ALIF utilisant un implant intervertebral en tantale est une technique fiable, reproductible et a faible morbidite. Elle s’accompagne, neanmoins, d’un taux important d’impactions immediates et secondaires, mais sans retentissement sur les resultats cliniques a court terme. Niveau de preuve IV.

Published
2021
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32. Essential Trace Elements in Roe Deer: Associations with Parasite Burden and Immune Phenotype in Two Contrasted Populations

Author

Bariod, Léa, primary, Saïd, Sonia, additional, Calenge, Clément, additional, Scheifler, Renaud, additional, Fritsch, Clémentine, additional, Peroz, Carole, additional, Benabed, Slimania, additional, Débias, François, additional, Duhayer, Jeanne, additional, Pardonnet, Sylvia, additional, Poirel, Marie-Thérèse, additional, Vuarin, Pauline, additional, and Bourgoin, Gilles, additional

Published
2023
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34. Activités pharmaceutiques relatives aux essais cliniques de médicaments et dispositifs médicaux réalisées au sein des établissements de santé – guide professionnel

Author

Lehmann, Audrey, primary, Flet, Laurent, additional, Bourgoin, Hélène, additional, Castet, Audrey, additional, Caturla, Laetitia, additional, Cransac, Amélie, additional, Djabarouti, Sarah, additional, Eyvrard, Frédéric, additional, Grand, Anaïs, additional, Guérin, Corinne, additional, Minoves, Mélanie, additional, Renon-Carron, Françoise, additional, and Bernard, Lise, additional

Published
2022
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35. Efficacité et tolérance du bérotralstat dans la prévention des crises récurrentes d’angiœdème héréditaire : analyse intermédiaire de l’étude observationnelle en vie réelle « BEROLIFE »

Author

Gobert, D., primary, Launay, D., additional, Boccon-Gibod, I., additional, De Moreuil, C., additional, Bourgoin-Heck, M., additional, Aubineau, M., additional, Debord-Peguet, S., additional, Jeandel, P.Y., additional, Jaussaud, R., additional, Du-Thanh, A., additional, Armengol, G., additional, Hoarau, C., additional, Ollivier, Y., additional, Pontille, F., additional, Guez, S., additional, Villedieu, M., additional, Crave, J.C., additional, Fain, O., additional, and Bouillet, L., additional

Published
2022
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39. VEGF, facteur tissulaire, marqueurs de la coagulation et de la fibrinolyse dans les malformations vasculaires à flux lent : étude prospective et impact du sirolimus

Author

Moineau, A.G., primary, Maruani, A., additional, Boccara, O., additional, Mazereeuw-Hautier, J., additional, Leducq, S., additional, Bessis, D., additional, Guibaud, L., additional, Vabres, P., additional, Mallet, S., additional, Barbarot, S., additional, Chiaverini, C., additional, Droitcourt, C., additional, Bursztejn, A.C., additional, Lengelle, C., additional, Woillard, J.B., additional, Herbreteau, D., additional, Le Touze, A., additional, Binet, A., additional, Morel, B., additional, Bourgoin, H., additional, Gissot, V., additional, Giraudeau, B., additional, Gruel, Y., additional, Tavernier, E., additional, and Rollin, J., additional

Published
2022
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40. Generalist nematodes dominate the nemabiome of roe deer in sympatry with sheep at a regional level

Author

Beaumelle, Camille, primary, Redman, Elizabeth, additional, Verheyden, Hélène, additional, Jacquiet, Philippe, additional, Bégoc, Noémie, additional, Veyssière, Florence, additional, Benabed, Slimania, additional, Cargnelutti, Bruno, additional, Lourtet, Bruno, additional, Poirel, Marie-Thérèse, additional, de Rijke, Jill, additional, Yannic, Glenn, additional, Gilleard, John S., additional, and Bourgoin, Gilles, additional

Published
2022
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44. Managing food allergy: GA2LEN guideline 2022

Author

Muraro, Antonella, primary, de Silva, Debra, additional, Halken, Susanne, additional, Worm, Margitta, additional, Khaleva, Ekaterina, additional, Arasi, Stefania, additional, Dunn-Galvin, Audrey, additional, Nwaru, Bright I., additional, De Jong, Nicolette W., additional, Rodríguez Del Río, Pablo, additional, Turner, Paul J., additional, Smith, Pete, additional, Begin, Philippe, additional, Angier, Elizabeth, additional, Arshad, Hasan, additional, Ballmer-Weber, Barbara, additional, Beyer, Kirsten, additional, Bindslev-Jensen, Carsten, additional, Cianferoni, Antonella, additional, Demoulin, Céline, additional, Deschildre, Antoine, additional, Ebisawa, Motohiro, additional, Fernandez-Rivas, Maria Montserrat, additional, Fiocchi, Alessandro, additional, Flokstra-de Blok, Bertine, additional, Gerdts, Jennifer, additional, Gradman, Josefine, additional, Grimshaw, Kate, additional, Jones, Carla, additional, Lau, Susanne, additional, Loh, Richard, additional, Alvaro Lozano, Montserrat, additional, Makela, Mika, additional, Marchisotto, Mary Jane, additional, Meyer, Rosan, additional, Mills, Clare, additional, Nilsson, Caroline, additional, Nowak-Wegrzyn, Anna, additional, Nurmatov, Ulugbek, additional, Pajno, Giovanni, additional, Podestà, Marcia, additional, Poulsen, Lars K., additional, Sampson, Hugh A., additional, Sanchez, Angel, additional, Schnadt, Sabine, additional, Szajewska, Hania, additional, Van Ree, Ronald, additional, Venter, Carina, additional, Vlieg-Boerstra, Berber, additional, Warner, Amena, additional, Wong, Gary, additional, Wood, Robert, additional, Zuberbier, Torsten, additional, Roberts, Graham, additional, Bansal, Priya, additional, Berni–Canani, Roberto, additional, Blumchen, Katharina, additional, Bonertz, Andreas, additional, Bourgoin-Heck, Melisande, additional, Ceylon, Ozlem, additional, Divaret-Chauveau, Amandine, additional, Fleischer, David, additional, Gomez, Maximiliano, additional, Groetch, Marion, additional, Hernandez, Domingo Barber, additional, Hjorth, Betina, additional, Hussey, Lydia Collins, additional, Knulst, André C., additional, Leung, Agnes, additional, Mack, Douglas, additional, Mahler, Vera, additional, Mori, Francesca, additional, Namazova-Baranova, Leyla, additional, Palosuo, Kati, additional, Parisi, Claudio Alberto Salvador, additional, Pastorino, Antonio Carlos, additional, Rudzeviciene, Odilija, additional, Said, Maria, additional, Sawiec, Piotr, additional, Sicherer, Scott, additional, Sato, Sakura, additional, and Zubchenko, Svitlana, additional

Published
2022
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45. Graded Prognostic Assessment (GPA) for Patients With Lung Cancer and Brain Metastases: Initial Report of the Small Cell Lung Cancer GPA and Update of the Non-Small Cell Lung Cancer GPA Including the Effect of Programmed Death Ligand 1 and Other Prognostic Factors

Author

Sperduto, Paul W., primary, De, Brian, additional, Li, Jing, additional, Carpenter, David, additional, Kirkpatrick, John, additional, Milligan, Michael, additional, Shih, Helen A., additional, Kutuk, Tugce, additional, Kotecha, Rupesh, additional, Higaki, Hajime, additional, Otsuka, Manami, additional, Aoyama, Hidefumi, additional, Bourgoin, Malie, additional, Roberge, David, additional, Dajani, Salah, additional, Sachdev, Sean, additional, Gainey, Jordan, additional, Buatti, John M., additional, Breen, William, additional, Brown, Paul D., additional, Ni, Lisa, additional, Braunstein, Steve, additional, Gallitto, Matthew, additional, Wang, Tony J.C., additional, Shanley, Ryan, additional, Lou, Emil, additional, Shiao, Jay, additional, Gaspar, Laurie E., additional, Tanabe, Satoshi, additional, Nakano, Toshimichi, additional, An, Yi, additional, Chiang, Veronica, additional, Zeng, Liang, additional, Soliman, Hany, additional, Elhalawani, Hesham, additional, Cagney, Daniel, additional, Thomas, Evan, additional, Boggs, Drexell H., additional, Ahluwalia, Manmeet S., additional, and Mehta, Minesh P., additional

Published
2022
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48. Early vascular imaging and key system strategies expedite carotid revascularization after transient ischemic attack and stroke

Author

Brammiya Sivakumar, Grant Stotts, Rany Shamloul, Dar Dowlatshahi, Sophia Gocan, and Aline Bourgoin

Subjects
Male, Canada, medicine.medical_specialty, Neurology, medicine.medical_treatment, Carotid endarterectomy, 030204 cardiovascular system & hematology, Revascularization, Time-to-Treatment, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, medicine, Humans, Carotid Stenosis, cardiovascular diseases, 030212 general & internal medicine, Stroke, Aged, Retrospective Studies, Endarterectomy, Carotid, Univariate analysis, Vascular imaging, business.industry, Guideline, Middle Aged, medicine.disease, Ischemic Attack, Transient, Ambulatory, Emergency medicine, Female, Stents, Surgery, Cardiology and Cardiovascular Medicine, business
Abstract

International guidelines recommend carotid revascularization within 14 days for patients with a symptomatic transient ischemic attack (TIA) or stroke event. However, significant delays in care persist, with only 9% of outpatients and 36% of inpatients in Ontario meeting this target. The study objective was to explore the influence of health system factors on carotid revascularization timelines.We conducted a retrospective chart review of all symptomatic TIA/stroke patients undergoing carotid endarterectomy or stenting at The Ottawa Hospital (2015-2016). The primary outcome was time from TIA/stroke to carotid revascularization. Health system variables of interest included location and timing of patient presentation, timelines to vascular imaging, and same-day collaboration between key services such as emergency, neurology, and surgery. Descriptive statistics and univariate analysis were used to determine statistically significant differences between groups.A total of 228 records met the inclusion criteria. The median time from TIA/stroke to carotid revascularization was 10 days, with 58% of patients meeting the 14-day guideline. Prompt patient presentation to emergency demonstrated significantly shorter timelines to surgery (7 days; P .001). Early vascular imaging was strongly correlated with early revascularization (4-5 days; P .001). In addition, collaboration from two or more care services enhanced timelines to surgery ranging from 2.0 to 6.5 days (P .001-.008).Early/emergency response to stroke symptoms was pivotal in achieving best practice recommendations for rapid carotid revascularization, emphasizing the need for ongoing public awareness. Emergency and ambulatory strategies to facilitate urgent vascular imaging, as well as mechanisms for same-day communication between teams require optimization to promote early revascularization.

Published
2020
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49. Note technique sur la reprise progressive des activités de médecine préventive à la levée du confinement le 11 mai – Gestion des protocoles vaccinaux

Author

M. A. Pellecuer, V. Legros, J. F. Audrin, E. Rosset, E. Gilot Fromont, M. P. Callait Cardinal, A. Kodjo, M. Abitbol, D. Grandjean, C. Muller, P. Rouch-Buck, M. Pepin, C. Bisson, E. Gaultier, L. Freyburger, M. H. Laaberki, G. Chaudieu, G. Bourgoin, F. Ayral, J. Cabrera Gonzalez, A. Charondiere, V. Thary, L. Zenner, and S. Le Poder

Subjects
Note Technique, Chat, Vaccination, Dog, COVID-19, Cat, Containment, Chien, Small Animals, Confinement
Abstract

Revue veterinaire clinique - Sous presse. Epreuves corrigees par l'auteur. Disponible en ligne depuis le samedi 6 juin 2020

Published
2020
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50. Mélanomes sur tatouage : deux observations et revue systématique de la littérature

Author

F. Cherkaoui El Baraka, C. Zeboulon, C. Sin, M. Grossin, R. Bourgoin, E. Mahé, Nicolas Kluger, C. Phan, and I. Ollivier

Subjects
Gynecology, 030207 dermatology & venereal diseases, 03 medical and health sciences, medicine.medical_specialty, 0302 clinical medicine, business.industry, medicine, Dermatology, Sun exposure, business
Abstract

Resume Introduction Quelques cas de melanomes sur tatouages ont ete rapportes. Le role du tatouage dans le developpement de tumeurs cutanees malignes est cependant tres discute. Nous rapportons deux nouvelles observations de melanomes se developpant sur des tatouages, completees d’une revue systematique de la litterature. Observations Cas 1. Un patient de 61 ans, de phototype IV, consultait pour une lesion nodulaire pigmentee de 4,5 × 3 cm apparue depuis un an, developpee sur un tatouage noir et rouge du dos. L’examen histologique de la lesion objectivait un melanome de type nodulaire ulcere, indice de Breslow a 7 mm. Le bilan d’extension ne trouvait pas de localisations secondaires. Cas 2. Un patient de 39 ans, de phototype II, portant un tatouage noir du bras consultait pour une lesion pigmentee cliniquement suspecte evoluant depuis plusieurs mois. L’exerese etait d’emblee realisee, confirmant le diagnostic de melanome de type SSM, developpe sur naevus preexistant, indice de Breslow 0,9 mm. Une reprise a 1 cm etait realisee et, avec un recul de 9 ans, il n’etait pas note de recidive. Discussion La revue systematique de la litterature trouvait 34 cas de melanomes survenus sur tatouage. Il existait une forte prevalence masculine (90,3 %) et un âge moyen relativement jeune (45,9 ans). Il s’agissait majoritairement de tatouages monochromes noir/bleu fonce (71,0 %). Le delai moyen entre la realisation du tatouage et l’apparition du melanome etait de 13,2 ans. La localisation la plus frequente du melanome etait le membre superieur (53,1 %) suivi du tronc (34,4 %). A l’examen anatomopathologique, il s’agissait dans 2 cas de melanomes in situ, et dans 13 cas, l’indice de Breslow etait inferieur ou egal a 1 mm. Dans 5 observations, une metastase ganglionnaire macroscopique ou microscopique (ganglion sentinelle) etait trouvee au diagnostic et dans une de ces observations etaient aussi observees des metastases cutanees en transit au diagnostic. L’hypothetique role du tatouage dans la carcinogenese est discute.

Published
2020
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