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34 results on '"Bonuccelli, U"'

5. Mitochondrial DNA haplogroups may influence Fabry disease phenotype

Author

Simoncini, C., primary, Chico, L., additional, Concolino, D., additional, Sestito, S., additional, Fancellu, L., additional, Boadu, W., additional, Sechi, G.P., additional, Feliciani, C., additional, Gnarra, M., additional, Zampetti, A., additional, Salviati, A., additional, Scarpelli, M., additional, Orsucci, D., additional, Bonuccelli, U., additional, Siciliano, G., additional, and Mancuso, M., additional

Published
2016
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6. Corrigendum to “Early detection of wearing off in Parkinson disease: The DEEP study” [Parkinsonism Relat Disorder 20 (2014) 204–211]

Author

Stocchi, F., primary, Antonini, A., additional, Barone, P., additional, Tinazzi, M., additional, Zappia, M., additional, Onofrj, M., additional, Ruggieri, S., additional, Morgante, L., additional, Bonuccelli, U., additional, Lopiano, L., additional, Pramstaller, P., additional, Albanese, A., additional, Attar, M., additional, Posocco, V., additional, Colombo, D., additional, and Abbruzzese, G., additional

Published
2015
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9. Early DEtection of wEaring off in Parkinson disease: The DEEP study

Author

Stocchi, F., primary, Antonini, A., additional, Barone, P., additional, Tinazzi, M., additional, Zappia, M., additional, Onofrj, M., additional, Ruggieri, S., additional, Morgante, L., additional, Bonuccelli, U., additional, Lopiano, L., additional, Pramstaller, P., additional, Albanese, A., additional, Attar, M., additional, Posocco, V., additional, Colombo, D., additional, and Abbruzzese, G., additional

Published
2014
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16. 25 Three years follow-up outcome of deferiprone for pantothenate kinase-associated neurodegeneration (PKAN)

Author

Cossu, G., primary, Murgia, D., additional, Melis, M., additional, Matta, G., additional, Galanello, R., additional, Barella, S., additional, Balocco, M., additional, Paribello, A., additional, Marcia, E., additional, Marchese, R., additional, Ruffinengo, U., additional, Bonuccelli, U., additional, Forni, G.L., additional, and Abbruzzese, G., additional

Published
2012
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17. The relationship between cerebral vascular disease and parkinsonism: The VADO study

Author

Antonini, A., primary, Vitale, C., additional, Barone, P., additional, Cilia, R., additional, Righini, A., additional, Bonuccelli, U., additional, Abbruzzese, G., additional, Ramat, S., additional, Petrone, A., additional, Quatrale, R., additional, Marconi, R., additional, Ceravolo, R., additional, Stefani, A., additional, Lopiano, L., additional, Zappia, M., additional, Capus, L., additional, Morgante, L., additional, Tamma, F., additional, Tinazzi, M., additional, Colosimo, C., additional, and Guerra, U.P., additional

Published
2012
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34. Validation and attempts of revision of the MDS-recommended tests for the screening of Parkinson's disease dementia

Author

Ubaldo Bonuccelli, Marco Vista, D. De Gaspari, Chiara Siri, Valeria Isella, Cristina Mapelli, Giovanni Pezzoli, Michele Poletti, Ildebrando Appollonio, Angelo Antonini, Isella, V, Mapelli, C, Siri, C, De Gaspari, D, Pezzoli, G, Antonini, A, Poletti, M, Bonuccelli, U, Vista, M, and Appollonio, I

Subjects
Male, Pediatrics, medicine.medical_specialty, Parkinson's disease, Neurology, Movement disorders, Neuropsychological Tests, Parkinson's disease dementia, M-PSI/02 - PSICOBIOLOGIA E PSICOLOGIA FISIOLOGICA, Sensitivity and Specificity, MDS guidelines, medicine, False positive paradox, Humans, Dementia, Mini Mental Parkinson, Aged, MED/26 - NEUROLOGIA, Mini–Mental State Examination, Receiver operating characteristic, medicine.diagnostic_test, Mini Mental State Examination, Parkinson Disease, Cognition, Female, ROC Curve, Algorithms, Geriatrics and Gerontology, Neurology (clinical), medicine.disease, MDS guideline, Physical therapy, medicine.symptom, Psychology
Abstract

The Movement Disorders Society (MDS) formulated diagnostic criteria and assessment guidelines for the screening of dementia in Parkinson's disease (PD). We carried out a validation of the cognitive measures suggested in the screening algorithm (i.e. the Mini Mental State Examination - MMSE - total score, serial 7s subtraction, 3-word recall, pentagons copy, and one minute letter fluency) in 86 patients with PD. Thirty-six percent of participants were diagnosed with dementia using the MDS algorithm, but with the Dementia Rating Scale instead of the MMSE. The original MDS procedure misclassified 11 patients (12.8%) as false negatives and 3 (3.5%) as false positives, leading to 65% sensitivity and 95% specificity. The main reason for misdiagnoses was insensitivity of the MMSE total score. Three attempts were made to reach a better screening performance, which warrants high sensitivity more than high specificity: 1. exclusion of the MMSE total score as a diagnostic requirement; 2. determination of a better cut off through Receiver Operating Characteristic curve analysis; 3. replacement of the MMSE with the equally undemanding, but more PD-specific, Mini Mental Parkinson. The first two strategies generally yielded high sensitivity, but poor specificity. The best outcome was achieved using a Mini Mental Parkinson total score

Published
2014

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