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Start Over Author "Bonde, J.P." Publisher elsevier bv
10 results on '"Bonde, J.P."'

3. Blood serum concentrations of perfluorinated compounds in men from Greenlandic Inuit and European populations

Author

Lindh, C.H., Rylander, L., Toft, G., Axmon, A., Rignell-Hydbom, A., Giwercman, A., Pedersen, H.S., Góalczyk, K., Ludwicki, J.K., Zvyezday, V., Vermeulen, R., Lenters, V.C., Heederik, D., Bonde, J.P., Jönsson, B.A.G., Risk Assessment of Toxic and Immunomodulatory Agents, Dep IRAS, Risk Assessment of Toxic and Immunomodulatory Agents, and Dep IRAS

Subjects
Adult, Male, Environmental Engineering, Chemistry(all), Health, Toxicology and Mutagenesis, Greenland, Population, Inuits, White People, Greenlandic, chemistry.chemical_compound, Blood serum, Tandem Mass Spectrometry, PFOS, Greenlandic Inuits, Humans, Environmental Chemistry, Inuit population, education, Fluorocarbons, education.field_of_study, Europeans, PFOA, Public Health, Environmental and Occupational Health, General Medicine, General Chemistry, Pollution, Perfluorinated compounds, Perfluorooctane, Alkanesulfonic Acids, Seafood, chemistry, Inuit, Environmental chemistry, Perfluorooctanoic acid, Caprylates, Environmental Sciences
Abstract

Perfluorinated compounds (PFCs), such as perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA), are used in large quantities. They are persistent and found in measurable levels in human serum around the world. They have been associated with developmental, hepatic, and carcinogenic effects in animal studies. The aim of the present study was to describe levels of PFCs in serum among Inuits from Greenland and inhabitants from Warsaw, Poland and Kharkiv, Ukraine. Furthermore, the aim was to define social- and lifestyle related determinants of exposure for these compounds. Serum levels of seven PFCs were analyzed by liquid chromatography/tandem mass spectrometry (LC/MS/MS). The concentrations of PFOS and PFOA were the highest of all PFCs in all three populations with a total amount of almost 90% of the PFCs. The mean levels of PFOS and PFOA were in the Greenlandic Inuits 52 and 4.8 ng mL(-1), in Poland 19 and 5.2 ng mL(-1), and in Ukraine 8.1 and 1.9 ng mL(-1), respectively. Thus, levels of PFCs in the serum of Inuits on Greenland were among the highest described in a general population whereas the levels in Poland were similar to other industrialized countries. The exposure in Ukraine was rather low. In the Greenlandic Inuit population, intake of seafood, tea, age and area of living were significant determinants of PFOS concentrations and explained about 22% of the variation. For the other populations no strong determinants were found.

Published
2012

5. Interactions between polymorphisms in the aryl hydrocarbon receptor signalling pathway and exposure to persistent organochlorine pollutants affect human semen quality

Author

Brokken, L.J.S., primary, Lundberg, P.J., additional, Spanò, M., additional, Manicardi, G.C., additional, Pedersen, H.S., additional, Struciński, P., additional, Góralczyk, K., additional, Zviezdai, V., additional, Jönsson, B.A.G., additional, Bonde, J.P., additional, Toft, G., additional, Lundberg Giwercman, Y., additional, and Giwercman, A., additional

Published
2014
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6. Non-linear association between androgen receptor CAG and GGN repeat lengths and reproductive parameters in fertile European and Inuit men

Author

Brokken, L.J.S., primary, Rylander, L., additional, Jönsson, B.A., additional, Spanò, M., additional, Pedersen, H.S., additional, Ludwicki, J.K., additional, Zviezdai, V., additional, Bizzaro, D., additional, Manicardi, G.C., additional, Toft, G., additional, Bonde, J.P., additional, Giwercman, A., additional, and Lundberg Giwercman, Y., additional

Published
2013
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