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1,376 results on '"Bollen, An"'

2. Development of a brief bedside tool to screen women sexual assault survivors for risk of persistent posttraumatic stress six months after sexual assault

Author

Walsh, Kate, primary, Short, Nicole, additional, Ji, Yin Yao, additional, An, Xin Ming, additional, Witkemper, Kristen D., additional, Lechner, Megan, additional, Bell, Kathy, additional, Black, Jenny, additional, Buchanan, Jennie, additional, Ho, Jeffrey, additional, Reed, Gordon, additional, Platt, Melissa, additional, Riviello, Ralph, additional, Martin, Sandra L., additional, Liberzon, Israel, additional, Rauch, Sheila A.M., additional, Bollen, Kenneth, additional, and McLean, Samuel A., additional

Published
2024
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4. Pathological findings associated with the updated European Society of Cardiology 2022 guidelines for preoperative cardiac testing: an observational cohort modelling study

Author

Stroda, Alexandra, primary, Mauermann, Eckhard, additional, Ionescu, Daniela, additional, Szczeklik, Wojciech, additional, De Hert, Stefan, additional, Filipovic, Miodrag, additional, Beck Schimmer, Beatrice, additional, Spadaro, Savino, additional, Matute, Purificación, additional, Ganter, Michael T., additional, Ovezov, Alexey, additional, Turhan, Sanem C., additional, van Waes, Judith, additional, Lagarto, Filipa, additional, Theodoraki, Kassiani, additional, Gupta, Anil, additional, Gillmann, Hans-Jörg, additional, Guzzetti, Luca, additional, Kotfis, Katarzyna, additional, Larmann, Jan, additional, Corneci, Dan, additional, Buggy, Donal J., additional, Howell, Simon J., additional, Lurati Buse, Giovanna, additional, Kemper, Johann, additional, Kohaupt, Lena, additional, Witzler, Jette, additional, Tuzhikov, Michael, additional, Roth, Sebastian, additional, Stroda, Alexandra, additional, M’Pembele, René, additional, Tenge, Theresa, additional, Schultze, Cornelia, additional, Verbarg, Nele, additional, Gehrke, Christian, additional, Klemann, Anna Katharina, additional, Hagebölling, Friederike, additional, Albrecht, Svenja, additional, Stroeder, Jakob, additional, Schubert, Ann-Kristin, additional, Espeter, Florian, additional, Russe, Benedikt, additional, Weigand, Markus A., additional, Bergmann, Lars, additional, Unterberg, Matthias, additional, Bischoff, Petra, additional, Pirzer, Raphael, additional, Rach, Patric Rene, additional, Ott, Klaus, additional, Zarbock, Alexander, additional, Kowark, Ana, additional, Neumann, Claudia, additional, Marchand, Bahareh, additional, Sponholz, Christoph, additional, Rueffert, Henrik, additional, Kramer, Mira, additional, Zacharowski, Kai, additional, Meybohm, Patrick, additional, Lindau, Simone, additional, Carollo, Melissa, additional, Novazzi, Cecilia, additional, Toso, Fiorenza, additional, Bacuzzi, Alessandro, additional, Ragazzi, Riccardo, additional, Volta, Carlo Alberto, additional, De Giorgi, Francesco, additional, Bacer, Barbara, additional, Federico, Antonio, additional, Chiumello, Davide, additional, Vetrugno, Luigi, additional, Castella, Alberto, additional, Tesoro, Simonetta, additional, Cotoia, Antonella, additional, Bignami, Elena, additional, Bellissima, Agrippino, additional, Cortegiani, Andrea, additional, Crisman, Marco, additional, Toninelli, Arturo, additional, Piazza, Ornella, additional, Mirabella, Lucia, additional, Bossolasco, Matteo, additional, Bona, Francesco, additional, Perdomo, Juan Manuel, additional, Coca-Martinez, Miquel, additional, Carramiñana, Albert, additional, Servén, Marta Giné, additional, González, Astrid Batalla, additional, Gil Sánchez, José Maria, additional, Becerra-Bolaños, Ángel, additional, Rodríguez-Pérez, Aurelio, additional, Soler, Anna Artigas, additional, Basso, Morena, additional, Font, Anna Peig, additional, Vernetta, Diana, additional, Santos, Julia Hernando, additional, Muñoz, Enrique Alday, additional, Olivares, Mercedes Cabellos, additional, Marco, Gregorio, additional, Lopez, Maria Bermudez, additional, Barrio, Javier, additional, Forés, María Isabel, additional, Boix, Estefanía, additional, Ayuso, Mercedes, additional, Petre, Bogdan Sorel, additional, Oprea, Ioana Sorina, additional, Latiș, Mihai Dan, additional, Margarit, Simona, additional, Vasian, Horatiu, additional, Tomescu, Dana, additional, Cîndea, Iulia, additional, Dirzu, Dan Sebastian, additional, Copotoiu, Sanda-Maria, additional, Moise, Alida, additional, Bubenek-Turconi, Serban, additional, Valeanu, Liana, additional, Wanner, Patrick Mark, additional, Djurdjevic, Mirjana, additional, Nuth, Sandra, additional, Seeberger, Esther, additional, Goettel, Nicolai, additional, Kamber, Firmin, additional, Ganter, Michael Thomas, additional, Gerber, Thomas Jan, additional, Schneebeli, Daniela, additional, Pregernig, Andreas, additional, Grape, Sina, additional, Tomala, Simon, additional, Pinto, Bernardo Bollen, additional, Żukowski, Maciej, additional, Zegan-Barańska, Małgorzata, additional, Karolak, Igor, additional, Krzych, Lukasz, additional, Czajka, Szymon, additional, Studzińska, Dorota, additional, Kluzik, Anna, additional, Koszel, Tomasz, additional, Pabjańczyk, Izabela, additional, Gajdosz, Anna, additional, Erkoc, Suheyla Karadag, additional, Meco, Basak Ceyda, additional, Koltka, Ahmet Kemalettin, additional, Dincer, Muserref Beril, additional, Ekmekçi, Perihan, additional, Saracoglu, Kemal Tolga, additional, Solmaz, Filiz Alkaya, additional, Ozcelik, Menekse, additional, Arun, Oguzhan, additional, Dilmen, Ozlem Korkmaz, additional, Preckel, Benedikt, additional, Hollmann, Markus W., additional, Hazen, Yannick, additional, Donald de Boer, Hans, additional, Epema, Anne, additional, Koopman, Seppe, additional, Van Lier, Felix, additional, Pinto, Rita, additional, Carrão, André, additional, Ribeiro, Daniel, additional, Mourão, Joana, additional, Coelho, Miguel, additional, Losa, Nuno, additional, Santos, Nuno, additional, Cabral, Luis, additional, Afonso, Diana, additional, Zenha, Sérgio, additional, Ramos, Cristina, additional, Hipólito, Carla, additional, Vasilaki, Maria, additional, Andreeva, Antonia, additional, Zaimi, Donika, additional, Chalkias, Athanasios, additional, Spyraki, Maria, additional, Rekatsina, Martina, additional, Tsaousi, Georgia, additional, Short, Anthony, additional, Meier, Sonja, additional, Madhuri, Thumuluru Kavitha, additional, Latham, Scott, additional, Knock, James, additional, Drummond, Andrew, additional, Ramsden, Fiona, additional, Kubisz-Pudelko, Agnieszka, additional, Walker, James, additional, Moppett, Iain, additional, White, Louise, additional, Jackson, Matthew, additional, Reschreiter, Henrik, additional, Innes, Richard, additional, Chew, Michelle, additional, Kalman, Sigridur, additional, Wallden, Jakob, additional, Schening, Anna, additional, Jonikaite, Lina, additional, Enlund, Anna, additional, De Baerdemaeker, Luc, additional, Morrison, Stuart, additional, Rex, Steffen, additional, Alexis, Alexandros, additional, Khoronenko, Viktoria E., additional, Belskii, Vladislav, additional, Kaznacheeva, Kseniya, additional, Gritsan, Alexey, additional, Kuzmanovska, Biljana, additional, Malinovska-Nikolovska, Liljana, additional, Barisin, Stjepan, additional, Poredos, Peter, additional, Arabadzhieva, Daniela, additional, Unic-Stojanovic, Dragana, additional, Golubović, Mladjan, additional, Fleischmann, Edith, additional, Kotzinger, Oskar, additional, Des Deserts, Marc Danguy, additional, Ducrocq, Nicolas, additional, Bonnet, Jean François, additional, Cusack, Barbara, additional, Calleja, Paul, additional, Hasani, Antigona, additional, and Nallbani, Rajmonda, additional

Published
2024
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6. Sex differences in response inhibition-related neural predictors of PTSD in recent trauma-exposed civilians

Author

Borst, Bibian, primary, Jovanovic, Tanja, additional, House, Stacey L., additional, Bruce, Steven E., additional, Harnett, Nathaniel G., additional, Roeckner, Alyssa R., additional, Ely, Timothy D., additional, Lebois, Lauren A.M., additional, Young, Dmitri, additional, Beaudoin, Francesca L., additional, An, Xinming, additional, Neylan, Thomas C., additional, Clifford, Gari D., additional, Linnstaedt, Sarah D., additional, Germine, Laura T., additional, Bollen, Kenneth A., additional, Rauch, Scott L., additional, Haran, John P., additional, Storrow, Alan B., additional, Lewandowski, Christopher, additional, Musey, Paul I., additional, Hendry, Phyllis L., additional, Sheikh, Sophia, additional, Jones, Christopher W., additional, Punches, Brittany E., additional, Hudak, Lauren A., additional, Pascual, Jose L., additional, Seamon, Mark J., additional, Datner, Elizabeth M., additional, Pearson, Claire, additional, Peak, David A., additional, Domeier, Robert M., additional, Rathlev, Niels K., additional, O'Neil, Brian J., additional, Sergot, Paulina, additional, Sanchez, Leon D., additional, Harte, Steven E., additional, Koenen, Karestan C., additional, Kessler, Ronald C., additional, McLean, Samuel A., additional, Ressler, Kerry J., additional, Stevens, Jennifer S., additional, and van Rooij, Sanne J.H., additional

Published
2024
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7. Dosimetric parameters predict radiation-induced temporal lobe necrosis in nasopharyngeal carcinoma patients: A systematic review and meta-analysis

Author

Dong, Jun, primary, Ng, Wai Tong, additional, Wong, Charlene H.L., additional, Li, Ji-Shi, additional, Bollen, Heleen, additional, Chow, James C.H., additional, Eisbruch, Avraham, additional, Lee, Anne W.M., additional, Lee, Victor H.F., additional, Ng, Sweet Ping, additional, Nuyts, Sandra, additional, Smee, Robert, additional, and Ferlito, Alfio, additional

Published
2024
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8. Effect of biologic treatment in uncontrolled severe chronic rhinosinusitis with nasal polyps in Belgium: A Real-World Data study

Author

Viskens, An-sofie, primary, Bollen, Laura, additional, Borgers, Elien, additional, Rogister, Florence, additional, Halewyck, Stijn, additional, Hox, Valerie, additional, Jorissen, Mark, additional, Lemmens, Winde, additional, Speleman, Kato, additional, Van Gerven, Laura, additional, Vanderveken, Olivier, additional, Verhaeghe, Benedicte, additional, and Hellings, Peter, additional

Published
2024
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9. Embryonic NIPP1 Depletion in Keratinocytes Triggers a Cell Cycle Arrest and Premature Senescence in Adult Mice

Author

Jonkhout, Marloes C.M., primary, Vanhessche, Tijs, additional, Ferreira, Mónica, additional, Verbinnen, Iris, additional, Withof, Fabienne, additional, Van der Hoeven, Gerd, additional, Szekér, Kathelijne, additional, Azhir, Zahra, additional, Lien, Wen-Hui, additional, Van Eynde, Aleyde, additional, and Bollen, Mathieu, additional

Published
2024
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10. Association between self-reported functional capacity and general postoperative complications: analysis of predefined outcomes of the MET-REPAIR international cohort study

Author

Roth, Sebastian, primary, M'Pembele, René, additional, Nienhaus, Johannes, additional, Mauermann, Eckhard, additional, Ionescu, Daniela, additional, Szczeklik, Wojciech, additional, De Hert, Stefan, additional, Filipovic, Miodrag, additional, Beck-Schimmer, Beatrice, additional, Spadaro, Savino, additional, Matute, Purificación, additional, Bolliger, Daniel, additional, Turhan, Sanem C., additional, van Waes, Judith, additional, Lagarto, Filipa, additional, Theodoraki, Kassiani, additional, Gupta, Anil, additional, Gillmann, Hans-Jörg, additional, Guzzetti, Luca, additional, Kotfis, Katarzyna, additional, Wulf, Hinnerk, additional, Larmann, Jan, additional, Corneci, Dan, additional, Chammartin, Frédérique, additional, Howell, Simon J., additional, Lurati Buse, Giovanna, additional, Roth, Sebastian, additional, Kemper, Johann, additional, Kohaupt, Lena, additional, Witzler, Jette, additional, Tuzhikov, Michael, additional, Stroda, Alexandra, additional, Tenge, Theresa, additional, Huhn, Ragnar, additional, Schultze, Cornelia, additional, Verbarg, Nele, additional, Gehrke, Christian, additional, Klemann, Anna Katharina, additional, Hagebölling, Friederike, additional, Albrecht, Svenja, additional, Stroeder, Jakob, additional, Schubert, Ann-Kristin, additional, Espeter, Florian, additional, Russe, Benedikt, additional, Weigand, Markus A., additional, Bergmann, Lars, additional, Unterberg, Matthias, additional, Bischoff, Petra, additional, Pirzer, Raphael, additional, Rach, Patric Rene, additional, Ott, Klaus, additional, Zarbock, Alexander, additional, Kowark, Ana, additional, Neumann, Claudia, additional, Marchand, Bahareh, additional, Sponholz, Christoph, additional, Rueffert, Henrik, additional, Kramer, Mira, additional, Piekarski, Florian, additional, Carollo, Melissa, additional, Novazzi, Cecilia, additional, Toso, Fiorenza, additional, Bacuzzi, Alessandro, additional, Ragazzi, Riccardo, additional, Volta, Carlo Alberto, additional, De Giorgi, Francesco, additional, Bacer, Barbara, additional, Federico, Antonio, additional, Chiumello, Davide, additional, Vetrugno, Luigi, additional, Castella, Alberto, additional, Tesoro, Simonetta, additional, Cotoia, Antonella, additional, Bignami, Elena, additional, Bellissima, Agrippino, additional, Cortegiani, Andrea, additional, Crisman, Marco, additional, Toninelli, Arturo, additional, Piazza, Ornella, additional, Mirabella, Lucia, additional, Bossolasco, Matteo, additional, Bona, Francesco, additional, Perdomo, Juan Manuel, additional, Coca-Martinez, Miquel, additional, Carramiñana, Albert, additional, Servén, Marta Giné, additional, González, Astrid Batalla, additional, Gil Sánchez, José Maria, additional, Becerra-Bolaños, Ángel, additional, Rodríguez-Pérez, Aurelio, additional, Soler, Anna Artigas, additional, Basso, Morena, additional, Font, Anna Peig, additional, Vernetta, Diana, additional, Santos, Julia Hernando, additional, Muñoz, Enrique Alday, additional, Olivares, Mercedes Cabellos, additional, Marco, Gregorio, additional, Lopez, Maria Bermudez, additional, Barrio, Javier, additional, Forés, María Isabel, additional, Boix, Estefanía, additional, Ayuso, Mercedes, additional, Petre, Bogdan Sorel, additional, Oprea, Ioana Sorina, additional, Latiș, Mihai Dan, additional, Margarit, Simona, additional, Vasian, Horatiu, additional, Tomescu, Dana, additional, Cîndea, Iulia, additional, Dirzu, Dan Sebastian, additional, Copotoiu, Sanda-Maria, additional, Moise, Alida, additional, Bubenek-Turconi, Serban, additional, Valeanu, Liana, additional, Wanner, Patrick Mark, additional, Djurdjevic, Mirjana, additional, Nuth, Sandra, additional, Seeberger, Esther, additional, Goettel, Nicolai, additional, Kamber, Firmin, additional, Ganter, Michael Thomas, additional, Gerber, Thomas Jan, additional, Schneebeli, Daniela, additional, Pregernig, Andreas, additional, Grape, Sina, additional, Tomala, Simon, additional, Pinto, Bernardo Bollen, additional, Żukowski, Maciej, additional, Zegan-Barańska, Małgorzata, additional, Karolak, Igor, additional, Krzych, Lukasz, additional, Czajka, Szymon, additional, Studzińska, Dorota, additional, Kluzik, Anna, additional, Koszel, Tomasz, additional, Pabjańczyk, Izabela, additional, Gajdosz, Anna, additional, Erkoc, Suheyla Karadag, additional, Meco, Basak Ceyda, additional, Koltka, Ahmet Kemalettin, additional, Dincer, Muserref Beril, additional, Ekmekçi, Perihan, additional, Saracoglu, Kemal Tolga, additional, Solmaz, Filiz Alkaya, additional, Ozcelik, Menekse, additional, Arun, Oguzhan, additional, Dilmen, Ozlem Korkmaz, additional, Preckel, Benedikt, additional, Hollmann, Markus W., additional, Hazen, Yannick, additional, Donald de Boer, Hans, additional, Epema, Anne, additional, Koopman, Seppe, additional, Van Lier, Felix, additional, Pinto, Rita, additional, Carrão, André, additional, Ribeiro, Daniel, additional, Mourão, Joana, additional, Coelho, Miguel, additional, Santos, Nuno, additional, Cabral, Luis, additional, Afonso, Diana, additional, Zenha, Sérgio, additional, Ramos, Cristina, additional, Hipólito, Carla, additional, Vasilaki, Maria, additional, Andreeva, Antonia, additional, Zaimi, Donika, additional, Chalkias, Athanasios, additional, Spyraki, Maria, additional, Rekatsina, Martina, additional, Tsaousi, Georgia, additional, Short, Anthony, additional, Meier, Sonja, additional, Madhuri, Thumuluru Kavitha, additional, Latham, Scott, additional, Knock, James, additional, Drummond, Andrew, additional, Ramsden, Fiona, additional, Kubisz-Pudelko, Agnieszka, additional, Walker, James, additional, Moppett, Iain, additional, White, Louise, additional, Jackson, Matthew, additional, Reschreiter, Henrik, additional, Innes, Richard, additional, Chew, Michelle, additional, Kalman, Sigridur, additional, Wallden, Jakob, additional, Schening, Anna, additional, Jonikaite, Lina, additional, Enlund, Anna, additional, De Baerdemaeker, Luc, additional, Morrison, Stuart, additional, Rex, Steffen, additional, Alexis, Alexandros, additional, Khoronenko, Viktoria E., additional, Ovezov, Alexey, additional, Belskii, Vladislav, additional, Kaznacheeva, Kseniya, additional, Gritsan, Alexey, additional, Kuzmanovska, Biljana, additional, Malinovska-Nikolovska, Liljana, additional, Barisin, Stjepan, additional, Poredos, Peter, additional, Arabadzhieva, Daniela, additional, Unic-Stojanovic, Dragana, additional, Golubović, Mladjan, additional, Fleischmann, Edith, additional, Kotzinger, Oskar, additional, Des Deserts, Marc Danguy, additional, Ducrocq, Nicolas, additional, Buggy, Donal J., additional, Bonnet, Jean François, additional, Cusack, Barbara, additional, Calleja, Paul, additional, Hasani, Antigona, additional, and Nallbani, Rajmonda, additional

Published
2024
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12. The Society of Thoracic Surgeons Adult Cardiac Surgery Database: Intraoperative Echocardiography Reporting

Author

Nicoara, Alina, primary, Fielding-Singh, Vikram, additional, Bollen, Bruce A., additional, Rhee, Amanda, additional, Mackay, Emily J., additional, Abernathy, James H., additional, Alfirevic, Andrej, additional, John, Sonia, additional, Kapoor, Anubhav, additional, MacDonald, Alistair J., additional, Qu, Jason Z., additional, Roca, Gabriela Querejeta, additional, Subramanian, Harikesh, additional, and Kertai, Miklos D., additional

Published
2024
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15. Derivation and Validation of a Brief Emergency Department-Based Prediction Tool for Posttraumatic Stress After Motor Vehicle Collision

Author

Christopher W. Jones, Xinming An, Yinyao Ji, Mochuan Liu, Donglin Zeng, Stacey L. House, Francesca L. Beaudoin, Jennifer S. Stevens, Thomas C. Neylan, Gari D. Clifford, Tanja Jovanovic, Sarah D. Linnstaedt, Laura T. Germine, Kenneth A. Bollen, Scott L. Rauch, John P. Haran, Alan B. Storrow, Christopher Lewandowski, Paul I. Musey, Phyllis L. Hendry, Sophia Sheikh, Brittany E. Punches, Michael S. Lyons, Michael C. Kurz, Robert A. Swor, Meghan E. McGrath, Lauren A. Hudak, Jose L. Pascual, Mark J. Seamon, Elizabeth M. Datner, Erica Harris, Anna M. Chang, Claire Pearson, David A. Peak, Roland C. Merchant, Robert M. Domeier, Niels K. Rathlev, Brian J. O'Neil, Paulina Sergot, Leon D. Sanchez, Steven E. Bruce, Mark W. Miller, Robert H. Pietrzak, Jutta Joormann, Deanna M. Barch, Diego A. Pizzagalli, John F. Sheridan, Jordan W. Smoller, Steven E. Harte, James M. Elliott, Karestan C. Koenen, Kerry J. Ressler, Ronald C. Kessler, and Samuel A. McLean

Subjects
Emergency Medicine
Abstract

To derive and initially validate a brief bedside clinical decision support tool that identifies emergency department patients at high risk of substantial, persistent posttraumatic stress symptoms after a motor vehicle collision.Derivation (n=1,282, 19 ED sites) and validation (n=282, 11 separate ED sites) data were obtained from adults prospectively enrolled in the Advancing Understanding of RecOvery afteR traumA study who were discharged from the ED after motor vehicle collision-related trauma. The primary outcome was substantial posttraumatic stress symptoms at 3 months (Posttraumatic Stress Disorder Checklist for Diagnostic and Statistical Manual of Mental Disorders-5 ≥38). Logistic regression derivation models were evaluated for discriminative ability using the area under the curve and the accuracy of predicted risk probabilities (Brier score). Candidate posttraumatic stress predictors assessed in these models (n=265) spanned a range of sociodemographic, baseline health, peritraumatic, and mechanistic domains. The final model selection was based on performance and ease of administration.Significant 3-month posttraumatic stress symptoms were common in the derivation (27%) and validation (26%) cohort. The area under the curve and Brier score of the final 8-question tool were 0.82 and 0.14 in the derivation cohort and 0.76 and 0.17 in the validation cohort.This simple 8-question tool demonstrates promise to risk-stratify individuals with substantial posttraumatic stress symptoms who are discharged to home after a motor vehicle collision. Both external validation of this instrument, and work to further develop more accurate tools, are needed. Such tools might benefit public health by enabling the conduct of preventive intervention trials and assisting the growing number of EDs that provide services to trauma survivors aimed at promoting psychological recovery.

Published
2023
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17. Neuropsychiatric manifestations and sleep disturbances with dolutegravir-based antiretroviral therapy versus standard of care in children and adolescents: a secondary analysis of the ODYSSEY trial

Author

Turkova, Anna, primary, White, Ellen, additional, Kekitiinwa, Adeodata R, additional, Mumbiro, Vivian, additional, Kaudha, Elizabeth, additional, Liberty, Afaaf, additional, Ahimbisibwe, Grace Miriam, additional, Moloantoa, Tumelo, additional, Srirompotong, Ussanee, additional, Mosia, Nozibusiso Rejoice, additional, Puthanakit, Thanyawee, additional, Kobbe, Robin, additional, Fortuny, Clàudia, additional, Kataike, Hajira, additional, Bbuye, Dickson, additional, Na-Rajsima, Sathaporn, additional, Coelho, Alexandra, additional, Lugemwa, Abbas, additional, Bwakura-Dangarembizi, Mutsa F, additional, Klein, Nigel, additional, Mujuru, Hilda A, additional, Kityo, Cissy, additional, Cotton, Mark F, additional, Ferrand, Rashida A, additional, Giaquinto, Carlo, additional, Rojo, Pablo, additional, Violari, Avy, additional, Gibb, Diana M, additional, Ford, Deborah, additional, Mehar (nee Abdulla), Amina Farhana, additional, Abraham, Pattamukkil, additional, Abrams, Elaine, additional, Acero, Judith, additional, Agaba, Gerald Muzorah, additional, Ahimbisibwe, Grace, additional, Ainebyoona, Barbara, additional, Akobye, Winnie, additional, Akhalwaya, Yasmeen, additional, Akoojee, Nazim, additional, Ali, Shabinah S., additional, Amuge, Pauline, additional, Andrea, Catherine, additional, Muñoz Fernandez, Maria Angeles, additional, Ankunda, Rogers, additional, Rutebarika, Diana Antonia, additional, Anugulruengkitt, Suvaporn, additional, Apollo, Tsitsi, additional, Archary, Moherndran, additional, Arendze, Ronelle, additional, Ategeka, Juliet, additional, Atim, Eunice, additional, Atwine, Lorna, additional, Babiker, Abdel, additional, Babirye, Sarah, additional, Babu, Enock, additional, Bagirigomwa, Edward, additional, Baita, Angella, additional, Balamusani, David, additional, Baliram, Patsy, additional, Baliruno, David, additional, Ball, Colin, additional, Balwa, Henry, additional, Bamford, Alasdair, additional, Bandi, Srini, additional, Barker, Dominique, additional, Barlow-Mosha, Linda, additional, Begum, Shazia, additional, Behuhuma, Osee, additional, Bernays, Sarah, additional, Besigye, Rogers, additional, Bester, Maria, additional, Bhiri, Joyline, additional, Bilardi, Davide, additional, Bird, Kristien, additional, Bollen, Pauline, additional, Borg, Chiara, additional, Borges Da Silva, Anne-Marie, additional, Brown, Jackie, additional, Bruno, Elena, additional, Bunupuradah, Torsak, additional, Burger, David, additional, Buthelezi, Nomzamo, additional, Bwakura-Dangarembizi, Mutsa, additional, Byaruhanga, Africanus, additional, Calvert, Joanna, additional, Casey, Petronelle, additional, Cassim, Haseena, additional, Cebekhulu, Sphiwee, additional, Chailert, Sanuphong, additional, Chalermpantmetagul, Suwalai, additional, Chamjamrat, Wanna, additional, Chan, Man, additional, Chandiwana, Precious, additional, Chankun, Thannapat, additional, Chanthaburanun, Sararut, additional, Chanto, Nuttawut, additional, Chidziva, Ennie, additional, Chikowore, Minenhle, additional, Chimanzi, Joy, additional, Chinwong, Dujrudee, additional, Chitongo, Stuart, additional, Chitsamatanga, Moses, additional, Choga, Joshua, additional, Chutima, Duangrat, additional, Clayden, Polly, additional, Colbers, Angela, additional, Compagnucci, Alexandra, additional, Constança Mendes, Ana, additional, Conway, Magda, additional, Crawley, Jane, additional, Cressey, Tim R, additional, Crisp, Jacky, additional, Matos, Ana Cristina, additional, Dadan, Sumaya, additional, Daglish, Jacqui, additional, Danaviah, Siva, additional, Daniel, Tseleng, additional, De Rossi, Anita, additional, Denjanta, Sukanda, additional, Dobbels, Els, additional, Dowie, Maria, additional, Dube, Prosper, additional, Dube, Benedictor, additional, Dudakia, Nimisha, additional, Elwana, Alice, additional, Epalza, Cristina, additional, Eram, David, additional, Erasmus, Juan, additional, Erim, Peter, additional, Escosa Garcia, Luis, additional, Essack, Zaakirah, additional, Estepa, Carolina, additional, Etima, Monica, additional, Fernandes, Alexandre, additional, Fernandez, Maite, additional, Fitzgerald, Felicity, additional, Flynn, Jacquie, additional, Fortuny Guasch, Claudia, additional, Foster, Caroline, additional, Fourie, George, additional, Fourie, Yolandie, additional, Foxall, Sophie, additional, Frank, Derusha, additional, Gandhi, Kate, additional, Garcia, India, additional, Gartner, Kathleen, additional, Gasa, Joshua, additional, Gasa, Gugu, additional, Gomez Rico, Coral, additional, Gomez-Pena, Daniel, additional, Gondo, Secrecy, additional, Goodman, Anna, additional, Gorreti Nakalema, Maria, additional, Gozhora, Winnie, additional, Greetanukroh, Pisut, additional, Gregorio Maranon, Biobanco, additional, Grossele, Tiziana, additional, Gwande, Shamiso, additional, Gwaze, Tapiwa, additional, Gwenzi, Tsitsi, additional, Hakim, James, additional, Hakiza, Emmanuel, additional, Kaka, Abdul Hamid, additional, Harley, Ashley, additional, Isaacs, Mornay, additional, Isabirye, Richard, additional, Ishemunyoro, Wilber, additional, Jacobs, Tom, additional, Jafta, Lungile, additional, Jamil, Nasir, additional, Janse van Rensburg, Anita Janse, additional, Jeaven, Vinesh, additional, Mellado Peña, Maria José, additional, Jourdain, Gonzague, additional, Juliet, Katabalwa, additional, Jumpimai, Thidarat, additional, Junkaew, Raungwit, additional, Jupimai, Thidarat, additional, Kaahwa, Winfred, additional, Kabasonga, Mildred, additional, Kaboggoza, Olivia, additional, Kadhuba, Rose Jacqueline, additional, Kaewbundit, Ampika, additional, Kaewmamueng, Kanyanee, additional, Kafufu, Bosco, additional, Kakayi, Brenda, additional, Kamboua, Phakamas, additional, Kanjanavanit, Suparat, additional, Kasangaki, Gladys, additional, Kasipong, Naruporn, additional, Kasozi, Miriam, additional, Katemba, Chrispus, additional, Kekane, Nkata, additional, Keminyeto, Edridah, additional, Khamduang, Woottichai, additional, Khamjakkaew, Warunee, additional, Khamkon, Jiraporn, additional, Khannak, Sasipass, additional, Khatngam, Orapin, additional, Khayanchoomnoom, Tassawan, additional, Khumalo, Busi, additional, Khunene, Mirriam, additional, Khusuwan, Suwimon, additional, Kibalama, Phionah, additional, Kibenge, Robinah, additional, Kirabira, Anthony, additional, Kityo, Cissy M, additional, Kiyimba, Lameck, additional, Klinprung, Soraya, additional, Kobusingye, Olivia, additional, Kobusungye, Josephine, additional, Kongponoi, Areerat, additional, Königs, Christoph, additional, Koole, Olivier, additional, Kouakam, Christelle, additional, Krueduangkam, Nitinart, additional, Kruenual, Namthip, additional, Kunjaroenrut, Nuananong, additional, Kyambadde, Raymonds, additional, Kyobutungi, Priscilla, additional, Kyomuhendo, Flavia, additional, Kyomukama, Erinah, additional, Lakha, Reshma, additional, Langa, Cleopatra, additional, Laomanit, Laddawan, additional, Lebotsa, Emily, additional, Leenasirimakul, Prattana, additional, Lekku, Lawrence, additional, Lensen, Sarah, additional, Leroy, Valériane, additional, Li, Jin, additional, Limplertjareanwanich, Juthamas, additional, Little, Emma, additional, Lutalo, Ezra, additional, Jimenez, Jose Luis, additional, Lyall, Hermione, additional, MacDonald, Candice, additional, Machache, Gladness, additional, Madlala, Penelope, additional, Madonsela, Tryphina, additional, Maduna, Nomfundo, additional, Maena, Joel, additional, Mahanontharit, Apicha, additional, Makanga, Collin, additional, Makola, Candice, additional, Makumbi, Shafic, additional, Malgraaf, Lucille, additional, Mamiane, Angelous, additional, Mantkowski, Felicia, additional, Mapfumo, Wendy, additional, Marques, Laura, additional, Mugagga, Agnes Mary, additional, Maseko, Lindiwe, additional, Masienyane, Tshepiso, additional, Mathiba, Ruth, additional, Matimba, Farai, additional, Mawlana, Sajeeda, additional, Mayanja, Emmanuel, additional, Mayat, Fatima, additional, Mbabazi, Ritah, additional, Mbadaliga, Nokuthula, additional, Mbasani, Faith, additional, McClaughlin, Kathleen, additional, McIlleron, Helen, additional, Meethaisong, Watchara, additional, Mendez Garcia, Patricia, additional, Miwanda, Annet, additional, Miranda, Carlota, additional, Mkhize, Siphiwe, additional, Mmolawa, Kgosimang, additional, Mngqibisa, Rosie, additional, Mohamed, Fatima, additional, Monametsi, Maletsatsi, additional, Montero, Samuel, additional, Moore, Cecilia L, additional, Mosia, Rejoice, additional, Moyo, Columbus, additional, Mthethwa, Mumsy, additional, Mudzingwa, Shepherd, additional, Mudzviti, Tawona, additional, Mujuru, Hilda, additional, Mujyambere, Emmanuel, additional, Mukanganiki, Trust, additional, Mukisa Williams, Cynthia, additional, Mulder, Mark, additional, Mulima, Disan, additional, Mulindwa, Alice, additional, Mupambireyi, Zivai, additional, Murciano Cabeza, Alba, additional, Murungi, Herbert, additional, Murungu, Dorothy, additional, Musarurwa, Sandra, additional, Musiime, Victor, additional, Musiime, Alex V, additional, Musisi, Maria, additional, Musoke, Philippa, additional, Musoke Nakirya, Barbara, additional, Musoro, Godfrey, additional, Musumba, Sharif, additional, Mustafa, Sobia, additional, Mutsai, Shirley, additional, Mwesigwa Rubondo, Phyllis, additional, Naabalamba, Mariam, additional, Nagawa, Immaculate, additional, Naidoo, Allemah, additional, Nakabuye, Shamim, additional, Nakabuye, Sarah, additional, Nakalanzi, Sarah, additional, Nalubwama, Justine, additional, Nalugo, Annet, additional, Nalusiba, Stella, additional, Namajja, Clementine, additional, Namanda, Sylvia, additional, Namayanja, Paula, additional, Nambi, Esther, additional, Namuddu, Rachael Kikabi, additional, Namukwaya, Stella, additional, Namuli, Florence, additional, Namusanje, Josephine, additional, Namwanje, Rosemary, additional, Nanan-kanjee, Anusha, additional, Nanduudu, Annet, additional, Nankunda, Charity, additional, Baddokwaya, Joanita Nankya, additional, Nannungi, Maria, additional, Nansamba, Winnie, additional, Nanthapisal, Kesdao, additional, Nanyonjo, Juliet, additional, Nasaazi, Claire, additional, Nascimento, Helena, additional, Nastouli, Eleni, additional, Songtaweesin, Wipaporn Natalie, additional, Nathoo, Kusum, additional, Natuhurira, Ian, additional, Nazzinda, Rashidah, additional, Ncgaba, Thabisa, additional, Ndigendawani, Milly, additional, Ndlovu, Makhosonke, additional, Nentsa, Georgina, additional, Ngampiyaskul, Chaiwat, additional, Ngcobo, Ntombenhle, additional, Ngo Giang Huong, Nicole, additional, Ngwaru, Pia, additional, Nhema, Ruth, additional, Ninsiima, Emily, additional, Ninsiima, Gloria, additional, Nkalo Phiri, Misheck, additional, Noguera Julian, Antoni, additional, Nolan, Monica, additional, Noppakaorattanamanee, Thornthun, additional, Nsibuka Kisekka, Muzamil, additional, Nsirim, Eniola, additional, Nundlal, Rashina, additional, Nunes, Rosita, additional, Nyantsa, Lungile, additional, Nyati, Mandisa, additional, O'Riordan, Sean, additional, Ocitti Labeja, Paul, additional, Odoch, Denis, additional, Oguntimehin, Rachel, additional, Ojok, Martin, additional, Onen, Geoffrey, additional, Orange, Wilma, additional, Ounchanum, Pradthana, additional, Ouma, Benson, additional, Padrao, Andreia, additional, Pako, Deborah, additional, Parker, Anna, additional, Pasko-Szcech, Malgorzata, additional, Patel, Reena, additional, Peongjakta, Rukchanok, additional, Petpranee, Turian, additional, Phillips, Tasmin, additional, Philps, Jackie, additional, Picault, Laura, additional, Pieterse, Sonja, additional, Pinheiro, Helena, additional, Pongprapass, Supawadee, additional, Pozniak, Anton, additional, Prendergast, Andrew, additional, Prieto Tato, Luis, additional, Puangmalai, Patcharee, additional, Rakgokong, Modiehi, additional, Ramos, Helena, additional, Ramsagar, Nastassja, additional, Rau, Cornelius, additional, Riault, Yoann, additional, Rojo Conejo, Pablo, additional, Clark, Basiimwa Roy, additional, Rubanga, Eddie, additional, Rubinga, Baker, additional, Ruklao, Chutima, additional, Runarassamee, Pattira, additional, Saenjum, Chalermpong, additional, Saewtrakool, Chayakorn, additional, Saidi, Yacine, additional, Sainz Costa, Talia, additional, Saisaengjan, Chutima, additional, Sakwa, Rebecca, additional, Sarfati, Tatiana, additional, Sbisi, Noshalaza, additional, Scheppers, Dihedile, additional, Schultze-Strasser, Stephan, additional, Schulze-Sturm, Ulf, additional, Scott, Karen, additional, Seeley, Janet, additional, Serunjogi, Robert, additional, Sewnarain, Leora, additional, Shakeshaft, Clare, additional, Sidhoo, Subashinie, additional, Shibemba, Mercy, additional, Shingadia, Delane, additional, Singh, Sheleika, additional, Sirirungsi, Wasna, additional, Sithebe, Sibongile, additional, Smit, Theresa, additional, Smith, Kurt, additional, Smuts, Marlize, additional, Spyer, Moira, additional, Sripaoraya, Worathip, additional, Srisuk, Warunee, additional, Ssenyonga, Mark, additional, Sudsaard, Patamawadee, additional, Sukrakanchana, Praornsuda, additional, Tearsansern, Pathanee, additional, Teixeira, Carla, additional, Than-in-at, Kanchana, additional, Thapwai, Thitiwat, additional, Thaweesombat, Yupawan, additional, Thewsoongnoen, Jutarat, additional, Thiébaut, Rodolphe, additional, Thomason, Margaret, additional, Thrasyvoulou, Laura, additional, Thungkham, Khanungnit, additional, Tikabibamu, Judith, additional, Tinago, Gloria, additional, Trairat, Ketmookda, additional, Tudor-Williams, Gareth, additional, Tukamushaba, Mercy, additional, Tukwasibwe, Deogratiuos, additional, Tumusiime, Julius, additional, Tuna, Joana, additional, Turkova, Anna, additional, Turner, Rebecca, additional, Udomvised, Arttasid, additional, Vadee, Aasia, additional, Van Huyssteen, Hesti, additional, Van Looy, Nadine, additional, Variava, Ebrahim, additional, Vaughan-Gordon, Yvonne, additional, Vecchia, Giulio, additional, Vowden, Richard, additional, Waalewijn, Hylke, additional, Wampamba, Rebecca, additional, Welch, Steve, additional, Weller, Ian, additional, Weza, Sibusisiwe, additional, White, Ian, additional, Widuch, Kaja, additional, Wilkes, Helen, additional, Wimonklang, Sookpanee, additional, Wynne, Ben, additional, Yingyong, Pacharaporn, additional, Nakawungu, Zaam Zinda, additional, and Zuidewind, Peter, additional

Published
2023
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21. An eye-tracking study of biased attentional processing of emotional faces in severe alcohol use disorder

Author

Arthur, Pabst, Zoé, Bollen, Nicolas, Masson, Pauline, Billaux, Philippe, de Timary, and Pierre, Maurage

Subjects
Psychiatry and Mental health, Clinical Psychology
Abstract

Social cognition impairments in severe alcohol use disorder (SAUD) are increasingly established. However, fundamental aspects of social cognition, and notably the attentional processing of socio-affective information, remain unexplored, limiting our understanding of underlying mechanisms. Here, we determined whether patients with SAUD show attentional biases to specific socio-affective cues, namely emotional faces.In a modified dot-probe paradigm, 30 patients with SAUD and 30 demographically matched healthy controls (HC) were presented with pairs of neutral-emotional (angry, disgusted, happy, sad) faces while having their eye movements recorded. Indices of early/automatic (first fixations, latency to first fixations) and later/controlled (number of fixations, dwell-time) processes were computed.Patients with SAUD did not differ from HC in their attention to angry/disgusted/sad vs. neutral faces. However, patients with SAUD fixated/dwelled less on happy vs. neutral faces in the first block of stimuli than HC, who presented an attentional bias to happy faces.Sample-size was determined to detect medium-to-large effects and subtler ones may have been missed. Further, our cross-sectional design provides no explanation as to whether the evidenced biases precede or are a consequence of SAUD.These results extend the social cognition literature in SAUD to the attentional domain, by evidencing the absence of a controlled attentional bias toward positive social cues in SAUD. This may reflect reduced sensitivity to social reward and could contribute to higher order social cognition difficulties and social dysfunction.

Published
2023
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22. Efficacy, safety, and immunogenicity of a booster regimen of Ad26.COV2.S vaccine against COVID-19 (ENSEMBLE2): results of a randomised, double-blind, placebo-controlled, phase 3 trial

Author

Karin Hardt, An Vandebosch, Jerald Sadoff, Mathieu Le Gars, Carla Truyers, David Lowson, Ilse Van Dromme, Johan Vingerhoets, Tobias Kamphuis, Gert Scheper, Javier Ruiz-Guiñazú, Saul N Faust, Christoph D Spinner, Hanneke Schuitemaker, Johan Van Hoof, Macaya Douoguih, Frank Struyf, Brian T. Garibaldi, Timothy E. Albertson, Christian Sandrock, Janet S. Lee, Mark R. Looney, Victor F. Tapson, Charles Shey Wiysonge, Luis Humberto Anaya Velarde, Daniel Backenroth, Jisha Bhushanan, Börries Brandenburg, Vicky Cárdenas, Bohang Chen, Fei Chen, Polan Chetty, Pei-Ling Chu, Kimberly Cooper, Jerome Custers, Hilde Delanghe, Anna Duca, Tracy Henrick, Jarek Juraszek, Catherine Nalpas, Monika Peeters, Jose Pinheiro, Sanne Roels, Martin F. Ryser, Jose Salas, Samantha Santoro Matias, Ilse Scheys, Pallavi Shetty, Georgi Shukarev, Jeffrey Stoddard, Willem Talloen, NamPhuong Tran, Nathalie Vaissiere, Elisabeth van Son-Palmen, Jiajun Xu, Erin A. Goecker, Alexander L. Greninger, Keith R. Jerome, Pavitra Roychoudhury, Simbarashe G. Takuva, Jose Luis Accini Mendoza, Eric Achtyes, Habibul Ahsan, Azhar Alhatemi, Nancy Allen, Jose R. Arribas, Ghazaleh Bahrami, Lucia Bailon, Ali Bajwa, Jonathan Baker, Mira Baron, Susana Benet, Driss Berdaï, Patrick Berger, Todd Bertoch, Claire Bethune, Sybille Bevilacqua, Maria Silvia Biagioni Santos, Ian Binnian, Karen Bisnauthsing, Jean-Marc Boivin, Hilde Bollen, Sandrine Bonnet, Alberto M. Borobia, Elisabeth Botelho-Nevers, Phil Bright, Vianne Britten, Claire Brown, Amanda Buadi, Erik Buntinx, Lesley Burgess, Larry Bush, Maria Rosario Capeding, Quito Osuna Carr, Amparo Carrasco Mas, Hélène Catala, Katrina Cathie, T. Shawn Caudill, Fernando Cereto Castro, Kénora Chau, Steven Chavoustie, Marie Chowdhury, Nicolas Chronos, Paola Cicconi, Liliana Cifuentes, Sara Maria Cobo, Helen Collins, Hayley Colton, Carlos Rolando G. Cuaño, Valentino D'Onofrio, Paul Dargan, Thomas Darton, Peter Deane, Jose Luis Del Pozo, Inge Derdelinckx, Amisha Desai, Michael Dever, Beatriz Díaz-Pollán, Mark DiBuono, Matthew Doust, Christopher Duncan, Jose Maria Echave-Sustaeta, Frank Eder, Kimberly Ellis, Stanton Elzi, Stevan Emmett, Johannes Engelbrecht, Mim Evans, Theo Farah, Timothy Felton, João Pedro Ferreira, Catherine Floutier, Patrick Flume, Stacy Ford, Veronica Fragoso, Andrew Freedman, Emilia Frentiu, Christopher Galloway, Florence Galtier, Julia Garcia Diaz, Irene García García, Alcaide Garcia, Zoe Gardener, Pascale Gauteul, Steven Geller, Andrew Gibson, Claudia Gillet, Nicolas Girerd, Pierre-Olivier Girodet, Maria Tarcela Gler, Richard Glover, Herschel Don D. Go, Karishma Gokani, Damien Gonthier, Christopher Green, Richard Greenberg, Carl Griffin, Coert Grobbelaar, Adonis Guancia, Gloria Hakkarainen, James Harris, Michael Hassman, Deirdre Heimer, Elizabeth Hellstrom-Louw, Yoan Herades, Christopher Holroyd, Nazreen Hussen, Marie Grace Dawn Isidro, Yvonne Jackson, Manish Jain, Esaú Custódio João Filho, Daniel Johnson, Ben Jones, Natasha Joseph, Analyn Jumeras, Patricia Junquera, Johanna Kellett-Wright, Patrick Kennedy, Paul E. Kilgore, Kenneth Kim, Murray Kimmel, George Konis, Mark Kutner, Karine Lacombe, Odile Launay, Rajeka Lazarus, Samuel Lederman, Gigi Lefebvre, Katrina Lennon Collins, Isabel Leroux-Roels, Kenneth Wilson O. Lim, Muriel Lins, Edward Liu, Martin Llewelyn, Akbar Mahomed, Bernardo Porto Maia, Alícia Marín-Candon, Xavier Martínez-Gómez, Jean Benoit Martinot, Andrea Mazzella, Frank McCaughan, Louise McCormack, John McGettigan, Purvi Mehra, Rhonda Mejeur, Vicki Miller, Anthony Mills, Jose Molto Marhuenda, Prebashan Moodley, Marta Mora-Rillo, Beatriz Mothe, Daniel Mullan, Alasdair Munro, Paul Myers, Jeremy Nell, Tamara Newman Lobato Souza, Jane A. O'Halloran, Maria Dolores Ochoa Mazarro, Abigail Oliver, Jose Millan Onate Gutierrez, Jessica Ortega, Masaru Oshita, Susana Otero Romero, Jeffrey Scott Overcash, Daniel Owens, Alice Packham, Mihaela Pacurar, Leonardo Paiva de Sousa, Adrian Palfreeman, Christian José Pallares, Rahul Patel, Suchet Patel, Leslie Pelkey, Denise Peluso, Florentina Penciu, S. Jerry Pinto, Kevin Pounds, Joe Pouzar, Antoinette Pragalos, Rachel Presti, David Price, Ehsaan Qureshi, José Valdez Ramalho Madruga, Mayur Ramesh, Bruce Rankin, Béatrice Razat, Breno Riegel Santos, Robert Riesenberg, Ernie Riffer, Siobhan Roche, Katie Rose, Pietro Rosellini, Patrick Rossignol, Beth Safirstein, Hernan Salazar, Gregorio Sanchez Vallejo, Smrithi Santhosh, Enrique Seco-Meseguer, Michael Seep, Emma Sherry, Philip Short, Patrick Soentjens, Joel Solis, Alejandro Soriano Viladomiu, Caroline Sorli, Selwyn Spangenthal, Niamh Spence, Elaine Stephenson, Cynthia Strout, Ronald Surowitz, Kristy Michelle Taladua, David Tellalian, Claire Thalamas, Nang Thiriphoo, Judith Thomas, Nicholas Thomas, Guillermo Trout, Mikel Urroz, Bernard Veekmans, Laurent Veekmans, Ralph Elvi M. Villalobos, Sarah Warren, Brian Webster, Alexander White, Gail Williams, Hayes Williams, Barbara Wilson, Alan Winston, Martin Wiselka, and Marcus Zervos

Subjects
Adult, Vaccines, COVID-19 Vaccines, Immunogenicity, Vaccine, Infectious Diseases, Adolescent, Ad26COVS1, Double-Blind Method, SARS-CoV-2, Humans, COVID-19, Antibodies, Viral
Abstract

Despite the availability of effective vaccines against COVID-19, booster vaccinations are needed to maintain vaccine-induced protection against variant strains and breakthrough infections. This study aimed to investigate the efficacy, safety, and immunogenicity of the Ad26.COV2.S vaccine (Janssen) as primary vaccination plus a booster dose.ENSEMBLE2 is a randomised, double-blind, placebo-controlled, phase 3 trial including crossover vaccination after emergency authorisation of COVID-19 vaccines. Adults aged at least 18 years without previous COVID-19 vaccination at public and private medical practices and hospitals in Belgium, Brazil, Colombia, France, Germany, the Philippines, South Africa, Spain, the UK, and the USA were randomly assigned 1:1 via a computer algorithm to receive intramuscularly administered Ad26.COV2.S as a primary dose plus a booster dose at 2 months or two placebo injections 2 months apart. The primary endpoint was vaccine efficacy against the first occurrence of molecularly confirmed moderate to severe-critical COVID-19 with onset at least 14 days after booster vaccination, which was assessed in participants who received two doses of vaccine or placebo, were negative for SARS-CoV-2 by PCR at baseline and on serology at baseline and day 71, had no major protocol deviations, and were at risk of COVID-19 (ie, had no PCR-positive result or discontinued the study before day 71). Safety was assessed in all participants; reactogenicity, in terms of solicited local and systemic adverse events, was assessed as a secondary endpoint in a safety subset (approximately 6000 randomly selected participants). The trial is registered with ClinicalTrials.gov, NCT04614948, and is ongoing.Enrolment began on Nov 16, 2020, and the primary analysis data cutoff was June 25, 2021. From 34 571 participants screened, the double-blind phase enrolled 31 300 participants, 14 492 of whom received two doses (7484 in the Ad26.COV2.S group and 7008 in the placebo group) and 11 639 of whom were eligible for inclusion in the assessment of the primary endpoint (6024 in the Ad26.COV2.S group and 5615 in the placebo group). The median (IQR) follow-up post-booster vaccination was 36·0 (15·0-62·0) days. Vaccine efficacy was 75·2% (adjusted 95% CI 54·6-87·3) against moderate to severe-critical COVID-19 (14 cases in the Ad26.COV2.S group and 52 cases in the placebo group). Most cases were due to the variants alpha (B.1.1.7) and mu (B.1.621); endpoints for the primary analysis accrued from Nov 16, 2020, to June 25, 2021, before the global dominance of delta (B.1.617.2) or omicron (B.1.1.529). The booster vaccine exhibited an acceptable safety profile. The overall frequencies of solicited local and systemic adverse events (evaluated in the safety subset, n=6067) were higher among vaccine recipients than placebo recipients after the primary and booster doses. The frequency of solicited adverse events in the Ad26.COV2.S group were similar following the primary and booster vaccinations (local adverse events, 1676 [55·6%] of 3015 vs 896 [57·5%] of 1559, respectively; systemic adverse events, 1764 [58·5%] of 3015 vs 821 [52·7%] of 1559, respectively). Solicited adverse events were transient and mostly grade 1-2 in severity.A homologous Ad26.COV2.S booster administered 2 months after primary single-dose vaccination in adults had an acceptable safety profile and was efficacious against moderate to severe-critical COVID-19. Studies assessing efficacy against newer variants and with longer follow-up are needed.Janssen ResearchDevelopment.

Published
2022
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23. Patent foramen ovale and perioperative stroke in noncardiac surgery: a systematic review and meta-analysis

Author

Gael Rais, Paola Vassallo, Raoul Schorer, Bernardo Bollen Pinto, and Alessandro Putzu

Subjects
Adult, Stroke, Observational Studies as Topic, Anesthesiology and Pain Medicine, Humans, Foramen Ovale, Patent, Prospective Studies, Neurosurgical Procedures, Retrospective Studies
Abstract

Patent foramen ovale (PFO) is associated with perioperative stroke in noncardiac surgery. The magnitude of this association was assessed in a systematic review and meta-analysis.Electronic databases were searched up to June 2022 for studies assessing the association between patent foramen ovale and perioperative stroke in adult patients undergoing noncardiac surgery. The primary analysis was limited to studies reporting effect estimates adjusted for significant clinical confounders. We calculated the adjusted odds ratio (aOR) and 95% confidence interval (CI).We included nine retrospective and two prospective observational studies, including 21 257 082 patients. The presence of a patent foramen ovale was independently associated with stroke at 30 days after surgery (aOR=6.68 [95% CI: 3.51-12.73]; P0.001) and at longest follow-up available (aOR=7.36 [95% CI: 3.56-15.21]; P0.001). The odds of stroke at 30 days varied according to surgical specialty: neurosurgery (aOR=4.52 [95% CI: 3.17-6.43]), vascular surgery (aOR=7.15 [95% CI: 2.52-20.22]), thoracic surgery (aOR=10.64 [95% CI: 5.97-18.98]), orthopaedic surgery (aOR=11.85 [95% CI: 5.38-26.08]), general surgery (aOR=14.40 [95% CI: 10.88-19.06]), and genitourinary surgery (aOR=17.28 [95% CI: 10.36-28.84]).The presence of a patent foramen ovale is associated with a large and consistent increase in odds of stroke across all explored surgical settings. Prospective trials should further explore this association by systematically assessing patent foramen ovale and stroke prevalence and identifying a specific population at risk. This is crucial for the elaboration of prevention plans and may improve perioperative outcomes.

Published
2022
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26. The new Batch Mode Ion Source for stand-alone operation at the Facility for Rare Isotope Beams (FRIB)

Author

Sumithrarachchi, C.S., primary, Liu, Y., additional, Rogers, S.N., additional, Schwarz, S., additional, Bollen, G., additional, Gamage, N., additional, Henriques, A., additional, Lapierre, A., additional, Ringle, R., additional, Yandow, I., additional, Villari, A.C.C., additional, Domnanich, K.A., additional, Satija, S., additional, Severin, G.W., additional, Au, M., additional, Ballof, J., additional, Garcia, Y.N. Vila, additional, Owen, M., additional, Reis, E., additional, Rothe, S., additional, and Stegemann, S., additional

Published
2023
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27. Preparation of stable and long-lived source samples for the stand-alone beam program at the facility for rare isotope beams

Author

Domnanich, Katharina A., primary, Satija, Samridhi, additional, Bodnar, Vladyslav S., additional, Bollen, Georg, additional, Kleinfeldt, Chloe R., additional, Liu, Yuan, additional, Rogers, Sierra, additional, Schwarz, Stefan, additional, Severin, Gregory W., additional, Sumithrarachchi, Chandana, additional, and Villari, Antonio C.C., additional

Published
2023
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28. Metallic wool for enhanced thermal conductivity of phase change materials

Author

Favache, Audrey, Bollen, Pierre, Bollen, Xavier, Baudoin, Gilles, Pardoen, Thomas, UCL - SST/IMMC/IMAP - Materials and process engineering, and UCL - SST/LAB - Louvain research institute for Landscape, Architecture, Built environment

Subjects
Natural convection, Heat transfer, General Engineering, Metal wool, Condensed Matter Physics, Phase change material
Abstract

The heat transfer potential of Phase Change Materials (PCMs) is augmented by the insertion of a metallic wool with high thermal conductivity. Apparent thermal heat conductivity has been determined experimentally in the solid and in the liquid phase for different wool contents. Heat transfer is enhanced by the addition of wool in solid phase, but is mitigated in liquid phase by the restriction of natural convection. The difference in heat transfer efficiency in the liquid and solid phase induces an asymmetric behavior between the melting and solidification configurations. The behavior of metallic wool-PCM composites is very similar to metallic foam-PCM hybrids studied in literature. As shown on the basis of rational material selection, the addition of a metallic wool constitutes in the practice a cost and process effective way to control the heat transfer potential.

Published
2023

29. An eye-tracking study of biased attentional processing of emotional faces in severe alcohol use disorder

Author

UCL - SSH/IACS - Institute of Analysis of Change in Contemporary and Historical Societies, Pabst, Arthur, Bollen, Zoé, Masson, Nicolas, Billaux, Pauline, de Timary, Philippe, Maurage, Pierre, UCL - SSH/IACS - Institute of Analysis of Change in Contemporary and Historical Societies, Pabst, Arthur, Bollen, Zoé, Masson, Nicolas, Billaux, Pauline, de Timary, Philippe, and Maurage, Pierre

Abstract

Background Social cognition impairments in severe alcohol use disorder (SAUD) are increasingly established. However, fundamental aspects of social cognition, and notably the attentional processing of socio-affective information, remain unexplored, limiting our understanding of underlying mechanisms. Here, we determined whether patients with SAUD show attentional biases to specific socio-affective cues, namely emotional faces. Method In a modified dot-probe paradigm, 30 patients with SAUD and 30 demographically matched healthy controls (HC) were presented with pairs of neutral-emotional (angry, disgusted, happy, sad) faces while having their eye movements recorded. Indices of early/automatic (first fixations, latency to first fixations) and later/controlled (number of fixations, dwell-time) processes were computed. Results Patients with SAUD did not differ from HC in their attention to angry/disgusted/sad vs. neutral faces. However, patients with SAUD fixated/dwelled less on happy vs. neutral faces in the first block of stimuli than HC, who presented an attentional bias to happy faces. Limitations Sample-size was determined to detect medium-to-large effects and subtler ones may have been missed. Further, our cross-sectional design provides no explanation as to whether the evidenced biases precede or are a consequence of SAUD. Conclusions These results extend the social cognition literature in SAUD to the attentional domain, by evidencing the absence of a controlled attentional bias toward positive social cues in SAUD. This may reflect reduced sensitivity to social reward and could contribute to higher order social cognition difficulties and social dysfunction.

Published
2023

34. Proton Beam Radiation Therapy for Oropharyngeal Squamous Cell Carcinoma

Author

Mendenhall, William M., primary, Beitler, Jonathan J., additional, Saba, Nabil F., additional, Shaha, Ashok R., additional, Nuyts, Sandra, additional, Strojan, Primož, additional, Bollen, Heleen, additional, Cohen, Oded, additional, Smee, Robert, additional, Ng, Sweet Ping, additional, Eisbruch, Avraham, additional, Ng, Wai Tong, additional, Kirwan, Jessica M., additional, and Ferlito, Alfio, additional

Published
2023
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35. Derivation and Validation of a Brief Emergency Department-Based Prediction Tool for Posttraumatic Stress After Motor Vehicle Collision

Author

Jones, Christopher W., primary, An, Xinming, additional, Ji, Yinyao, additional, Liu, Mochuan, additional, Zeng, Donglin, additional, House, Stacey L., additional, Beaudoin, Francesca L., additional, Stevens, Jennifer S., additional, Neylan, Thomas C., additional, Clifford, Gari D., additional, Jovanovic, Tanja, additional, Linnstaedt, Sarah D., additional, Germine, Laura T., additional, Bollen, Kenneth A., additional, Rauch, Scott L., additional, Haran, John P., additional, Storrow, Alan B., additional, Lewandowski, Christopher, additional, Musey, Paul I., additional, Hendry, Phyllis L., additional, Sheikh, Sophia, additional, Punches, Brittany E., additional, Lyons, Michael S., additional, Kurz, Michael C., additional, Swor, Robert A., additional, McGrath, Meghan E., additional, Hudak, Lauren A., additional, Pascual, Jose L., additional, Seamon, Mark J., additional, Datner, Elizabeth M., additional, Harris, Erica, additional, Chang, Anna M., additional, Pearson, Claire, additional, Peak, David A., additional, Merchant, Roland C., additional, Domeier, Robert M., additional, Rathlev, Niels K., additional, O'Neil, Brian J., additional, Sergot, Paulina, additional, Sanchez, Leon D., additional, Bruce, Steven E., additional, Miller, Mark W., additional, Pietrzak, Robert H., additional, Joormann, Jutta, additional, Barch, Deanna M., additional, Pizzagalli, Diego A., additional, Sheridan, John F., additional, Smoller, Jordan W., additional, Harte, Steven E., additional, Elliott, James M., additional, Koenen, Karestan C., additional, Ressler, Kerry J., additional, Kessler, Ronald C., additional, and McLean, Samuel A., additional

Published
2023
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36. Dolutegravir twice-daily dosing in children with HIV-associated tuberculosis: a pharmacokinetic and safety study within the open-label, multicentre, randomised, non-inferiority ODYSSEY trial

Author

Turkova, Anna, primary, Waalewijn, Hylke, additional, Chan, Man K, additional, Bollen, Pauline D J, additional, Bwakura-Dangarembizi, Mutsa F, additional, Kekitiinwa, Adeodata R, additional, Cotton, Mark F, additional, Lugemwa, Abbas, additional, Variava, Ebrahim, additional, Ahimbisibwe, Grace Miriam, additional, Srirompotong, Ussanee, additional, Mumbiro, Vivian, additional, Amuge, Pauline, additional, Zuidewind, Peter, additional, Ali, Shabinah, additional, Kityo, Cissy M, additional, Archary, Moherndran, additional, Ferrand, Rashida A, additional, Violari, Avy, additional, Gibb, Diana M, additional, Burger, David M, additional, Ford, Deborah, additional, Colbers, Angela, additional, Mehar (nee Abdulla), Amina Farhana, additional, Abraham, Pattamukkil, additional, Abrams, Elaine, additional, Acero, Judith, additional, Agaba, Gerald Muzorah, additional, Ahimbisibwe, Grace, additional, Ainebyoona, Barbara, additional, Akobye, Winnie, additional, Akhalwaya, Yasmeen, additional, Akoojee, Nazim, additional, Ali, Shabinah S., additional, Andrea, Catherine, additional, Muñoz Fernandez, Maria Angeles, additional, Ankunda, Rogers, additional, Rutebarika, Diana Antonia, additional, Anugulruengkitt, Suvaporn, additional, Apollo, Tsitsi, additional, Arendze, Ronelle, additional, Ategeka, Juliet, additional, Atim, Eunice, additional, Atwine, Lorna, additional, Babiker, Abdel, additional, Babirye, Sarah, additional, Babu, Enock, additional, Bagirigomwa, Edward, additional, Baita, Angella, additional, Balamusani, David, additional, Baliram, Patsy, additional, Baliruno, David, additional, Ball, Colin, additional, Balwa, Henry, additional, Bamford, Alasdair, additional, Bandi, Srini, additional, Barker, Dominique, additional, Barlow-Mosha, Linda, additional, Bbuye, Dickson, additional, Begum, Shazia, additional, Behuhuma, Osee, additional, Bernays, Sarah, additional, Besigye, Rogers, additional, Bester, Maria, additional, Bhiri, Joyline, additional, Bilardi, Davide, additional, Bird, Kristien, additional, Bollen, Pauline, additional, Borg, Chiara, additional, Borges Da Silva, Anne-Marie, additional, Brown, Jackie, additional, Bruno, Elena, additional, Bunupuradah, Torsak, additional, Burger, David, additional, Buthelezi, Nomzamo, additional, Bwakura-Dangarembizi, Mutsa, additional, Byaruhanga, Africanus, additional, Calvert, Joanna, additional, Casey, Petronelle, additional, Cassim, Haseena, additional, Cebekhulu, Sphiwee, additional, Chailert, Sanuphong, additional, Chalermpantmetagul, Suwalai, additional, Chamjamrat, Wanna, additional, Chan, Man, additional, Chandiwana, Precious, additional, Chankun, Thannapat, additional, Chanthaburanun, Sararut, additional, Chanto, Nuttawut, additional, Chidziva, Ennie, additional, Chikowore, Minenhle, additional, Chimanzi, Joy, additional, Chinwong, Dujrudee, additional, Chitongo, Stuart, additional, Chitsamatanga, Moses, additional, Choga, Joshua, additional, Chutima, Duangrat, additional, Clayden, Polly, additional, Coelho, Alexandra, additional, Compagnucci, Alexandra, additional, Constança Mendes, Ana, additional, Conway, Magda, additional, Cotton, Mark F., additional, Crawley, Jane, additional, Cressey, Tim R., additional, Crisp, Jacky, additional, Matos, Ana Cristina, additional, Dadan, Sumaya, additional, Daglish, Jacqui, additional, Danaviah, Siva, additional, Daniel, Tseleng, additional, De Rossi, Anita, additional, Denjanta, Sukanda, additional, Dobbels, Els, additional, Dowie, Maria, additional, Dube, Prosper, additional, Dube, Benedictor, additional, Dudakia, Nimisha, additional, Elwana, Alice, additional, Epalza, Cristina, additional, Eram, David, additional, Erasmus, Juan, additional, Erim, Peter, additional, Escosa Garcia, Luis, additional, Essack, Zaakirah, additional, Estepa, Carolina, additional, Etima, Monica, additional, Fernandes, Alexandre, additional, Fernandez, Maite, additional, Fitzgerald, Felicity, additional, Flynn, Jacquie, additional, Fortuny Guasch, Claudia, additional, Foster, Caroline, additional, Fourie, George, additional, Fourie, Yolandie, additional, Foxall, Sophie, additional, Frank, Derusha, additional, Gandhi, Kate, additional, Garcia, India, additional, Gartner, Kathleen, additional, Gasa, Joshua, additional, Gasa, Gugu, additional, Giaquinto, Carlo, additional, Gibb, Diana M., additional, Gomez Rico, Coral, additional, Gomez-Pena, Daniel, additional, Gondo, Secrecy, additional, Goodman, Anna, additional, Gorreti Nakalema, Maria, additional, Gozhora, Winnie, additional, Greetanukroh, Pisut, additional, Gregorio Maranon, Biobanco, additional, Grossele, Tiziana, additional, Gwande, Shamiso, additional, Gwaze, Tapiwa, additional, Gwenzi, Tsitsi, additional, Hakim, James, additional, Hakiza, Emmanuel, additional, Kaka, Abdul Hamid, additional, Harley, Ashley, additional, Isaacs, Mornay, additional, Isabirye, Richard, additional, Ishemunyoro, Wilber, additional, Jacobs, Tom, additional, Jafta, Lungile, additional, Jamil, Nasir, additional, Janse van Rensburg, Anita Janse, additional, Jeaven, Vinesh, additional, Mellado Peña, Maria José, additional, Jourdain, Gonzague, additional, Juliet, Katabalwa, additional, Jumpimai, Thidarat, additional, Junkaew, Raungwit, additional, Jupimai, Thidarat, additional, Kaahwa, Winfred, additional, Kabasonga, Mildred, additional, Kaboggoza, Olivia, additional, Kadhuba, Rose Jacqueline, additional, Kaewbundit, Ampika, additional, Kaewmamueng, Kanyanee, additional, Kafufu, Bosco, additional, Kakayi, Brenda, additional, Kamboua, Phakamas, additional, Kanjanavanit, Suparat, additional, Kasangaki, Gladys, additional, Kasipong, Naruporn, additional, Kasozi, Miriam, additional, Kataike, Hajira, additional, Katemba, Chrispus, additional, Kaudha, Elizabeth, additional, Kekane, Nkata, additional, Kekitiinwa, Adeodata R., additional, Keminyeto, Edridah, additional, Khamduang, Woottichai, additional, Khamjakkaew, Warunee, additional, Khamkon, Jiraporn, additional, Khannak, Sasipass, additional, Khatngam, Orapin, additional, Khayanchoomnoom, Tassawan, additional, Khumalo, Busi, additional, Khunene, Mirriam, additional, Khusuwan, Suwimon, additional, Kibalama, Phionah, additional, Kibenge, Robinah, additional, Kirabira, Anthony, additional, Kityo, Cissy M., additional, Kiyimba, Lameck, additional, Klein, Nigel, additional, Klinprung, Soraya, additional, Kobbe, Robin, additional, Kobusingye, Olivia, additional, Kobusungye, Josephine, additional, Kongponoi, Areerat, additional, Königs, Christoph, additional, Koole, Olivier, additional, Kouakam, Christelle, additional, Krueduangkam, Nitinart, additional, Kruenual, Namthip, additional, Kunjaroenrut, Nuananong, additional, Kyambadde, Raymonds, additional, Kyobutungi, Priscilla, additional, Kyomuhendo, Flavia, additional, Kyomukama, Erinah, additional, Lakha, Reshma, additional, Langa, Cleopatra, additional, Laomanit, Laddawan, additional, Lebotsa, Emily, additional, Leenasirimakul, Prattana, additional, Lekku, Lawrence, additional, Lensen, Sarah, additional, Leroy, Valériane, additional, Li, Jin, additional, Liberty, Afaaf, additional, Limplertjareanwanich, Juthamas, additional, Little, Emma, additional, Lutalo, Ezra, additional, Jimenez, Jose Luis, additional, Lyall, Hermione, additional, MacDonald, Candice, additional, Machache, Gladness, additional, Madlala, Penelope, additional, Madonsela, Tryphina, additional, Maduna, Nomfundo, additional, Maena, Joel, additional, Mahanontharit, Apicha, additional, Makanga, Collin, additional, Makola, Candice, additional, Makumbi, Shafic, additional, Malgraaf, Lucille, additional, Mamiane, Angelous, additional, Mantkowski, Felicia, additional, Mapfumo, Wendy, additional, Marques, Laura, additional, Mugagga, Agnes Mary, additional, Maseko, Lindiwe, additional, Masienyane, Tshepiso, additional, Mathiba, Ruth, additional, Matimba, Farai, additional, Mawlana, Sajeeda, additional, Mayanja, Emmanuel, additional, Mayat, Fatima, additional, Mbabazi, Ritah, additional, Mbadaliga, Nokuthula, additional, Mbasani, Faith, additional, McClaughlin, Kathleen, additional, McIlleron, Helen, additional, Meethaisong, Watchara, additional, Mendez Garcia, Patricia, additional, Miwanda, Annet, additional, Miranda, Carlota, additional, Mkhize, Siphiwe, additional, Mmolawa, Kgosimang, additional, Mngqibisa, Rosie, additional, Mohamed, Fatima, additional, Moloantoa, Tumelo, additional, Monametsi, Maletsatsi, additional, Montero, Samuel, additional, Moore, Cecilia L., additional, Mosia, Rejoice, additional, Moyo, Columbus, additional, Mthethwa, Mumsy, additional, Mudzingwa, Shepherd, additional, Mudzviti, Tawona, additional, Mujuru, Hilda, additional, Mujyambere, Emmanuel, additional, Mukanganiki, Trust, additional, Mukisa Williams, Cynthia, additional, Mulder, Mark, additional, Mulima, Disan, additional, Mulindwa, Alice, additional, Mupambireyi, Zivai, additional, Murciano Cabeza, Alba, additional, Murungi, Herbert, additional, Murungu, Dorothy, additional, Musarurwa, Sandra, additional, Musiime, Victor, additional, Musiime, Alex V., additional, Musisi, Maria, additional, Musoke, Philippa, additional, Musoke Nakirya, Barbara, additional, Musoro, Godfrey, additional, Musumba, Sharif, additional, Mustafa, Sobia, additional, Mutsai, Shirley, additional, Mwesigwa Rubondo, Phyllis, additional, Naabalamba, Mariam, additional, Nagawa, Immaculate, additional, Naidoo, Allemah, additional, Nakabuye, Shamim, additional, Nakabuye, Sarah, additional, Nakalanzi, Sarah, additional, Nalubwama, Justine, additional, Nalugo, Annet, additional, Nalusiba, Stella, additional, Namajja, Clementine, additional, Namanda, Sylvia, additional, Namayanja, Paula, additional, Nambi, Esther, additional, Namuddu, Rachael Kikabi, additional, Namukwaya, Stella, additional, Namuli, Florence, additional, Namusanje, Josephine, additional, Namwanje, Rosemary, additional, Nanan-kanjee, Anusha, additional, Nanduudu, Annet, additional, Nankunda, Charity, additional, Baddokwaya, Joanita Nankya, additional, Nannungi, Maria, additional, Nansamba, Winnie, additional, Nanthapisal, Kesdao, additional, Nanyonjo, Juliet, additional, Na-Rajsima, Sathaporn, additional, Nasaazi, Claire, additional, Nascimento, Helena, additional, Nastouli, Eleni, additional, Songtaweesin, Wipaporn Natalie, additional, Nathoo, Kusum, additional, Natuhurira, Ian, additional, Nazzinda, Rashidah, additional, Ncgaba, Thabisa, additional, Ndigendawani, Milly, additional, Ndlovu, Makhosonke, additional, Nentsa, Georgina, additional, Ngampiyaskul, Chaiwat, additional, Ngcobo, Ntombenhle, additional, Ngo Giang Huong, Nicole, additional, Ngwaru, Pia, additional, Nhema, Ruth, additional, Ninsiima, Emily, additional, Ninsiima, Gloria, additional, Nkalo Phiri, Misheck, additional, Noguera Julian, Antoni, additional, Nolan, Monica, additional, Noppakaorattanamanee, Thornthun, additional, Nsibuka Kisekka, Muzamil, additional, Nsirim, Eniola, additional, Nundlal, Rashina, additional, Nunes, Rosita, additional, Nyantsa, Lungile, additional, Nyati, Mandisa, additional, O'Riordan, Sean, additional, Ocitti Labeja, Paul, additional, Odoch, Denis, additional, Oguntimehin, Rachel, additional, Ojok, Martin, additional, Onen, Geoffrey, additional, Orange, Wilma, additional, Ounchanum, Pradthana, additional, Ouma, Benson, additional, Padrao, Andreia, additional, Pako, Deborah, additional, Parker, Anna, additional, Pasko-Szcech, Malgorzata, additional, Patel, Reena, additional, Peongjakta, Rukchanok, additional, Petpranee, Turian, additional, Phillips, Tasmin, additional, Philps, Jackie, additional, Picault, Laura, additional, Pieterse, Sonja, additional, Pinheiro, Helena, additional, Pongprapass, Supawadee, additional, Pozniak, Anton, additional, Prendergast, Andrew, additional, Prieto Tato, Luis, additional, Puangmalai, Patcharee, additional, Puthanakit, Thanyawee, additional, Rakgokong, Modiehi, additional, Ramos, Helena, additional, Ramsagar, Nastassja, additional, Rau, Cornelius, additional, Riault, Yoann, additional, Rojo Conejo, Pablo, additional, Clark, Basiimwa Roy, additional, Rubanga, Eddie, additional, Rubinga, Baker, additional, Ruklao, Chutima, additional, Runarassamee, Pattira, additional, Saenjum, Chalermpong, additional, Saewtrakool, Chayakorn, additional, Saidi, Yacine, additional, Sainz Costa, Talia, additional, Saisaengjan, Chutima, additional, Sakwa, Rebecca, additional, Sarfati, Tatiana, additional, Sbisi, Noshalaza, additional, Scheppers, Dihedile, additional, Schultze-Strasser, Stephan, additional, Schulze-Sturm, Ulf, additional, Scott, Karen, additional, Seeley, Janet, additional, Serunjogi, Robert, additional, Sewnarain, Leora, additional, Shakeshaft, Clare, additional, Sidhoo, Subashinie, additional, Shibemba, Mercy, additional, Shingadia, Delane, additional, Singh, Sheleika, additional, Sirirungsi, Wasna, additional, Sithebe, Sibongile, additional, Smit, Theresa, additional, Smith, Kurt, additional, Smuts, Marlize, additional, Spyer, Moira, additional, Sripaoraya, Worathip, additional, Srisuk, Warunee, additional, Ssenyonga, Mark, additional, Sudsaard, Patamawadee, additional, Sukrakanchana, Praornsuda, additional, Tearsansern, Pathanee, additional, Teixeira, Carla, additional, Than-in-at, Kanchana, additional, Thapwai, Thitiwat, additional, Thaweesombat, Yupawan, additional, Thewsoongnoen, Jutarat, additional, Thiébaut, Rodolphe, additional, Thomason, Margaret, additional, Thrasyvoulou, Laura, additional, Thungkham, Khanungnit, additional, Tikabibamu, Judith, additional, Tinago, Gloria, additional, Trairat, Ketmookda, additional, Tudor-Williams, Gareth, additional, Tukamushaba, Mercy, additional, Tukwasibwe, Deogratiuos, additional, Tumusiime, Julius, additional, Tuna, Joana, additional, Turkova, Anna, additional, Turner, Rebecca, additional, Udomvised, Arttasid, additional, Vadee, Aasia, additional, Van Huyssteen, Hesti, additional, Van Looy, Nadine, additional, Vaughan-Gordon, Yvonne, additional, Vecchia, Giulio, additional, Vowden, Richard, additional, Wampamba, Rebecca, additional, Welch, Steve, additional, Weller, Ian, additional, Weza, Sibusisiwe, additional, White, Ellen, additional, White, Ian, additional, Widuch, Kaja, additional, Wilkes, Helen, additional, Wimonklang, Sookpanee, additional, Wynne, Ben, additional, Yingyong, Pacharaporn, additional, and Nakawungu, Zaam Zinda, additional

Published
2022
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37. Patient-reported outcome and cost implication of acute salvage of infected implant-based breast reconstruction with negative pressure wound therapy with Instillation (NPWTi) compared to standard care

Author

Shameem A Haque, Afshin Mosahebi, Edward Bollen, Ibby Younis, and Muholan Kanapathy

Subjects
Reoperation, medicine.medical_specialty, Prosthesis-Related Infections, Breast Implants, Mammaplasty, medicine.medical_treatment, Breast Neoplasms, 030230 surgery, law.invention, 03 medical and health sciences, 0302 clinical medicine, Patient satisfaction, law, Negative-pressure wound therapy, medicine, Humans, Patient Reported Outcome Measures, Therapeutic Irrigation, Average cost, Retrospective Studies, Salvage Therapy, business.industry, Middle Aged, Anti-Bacterial Agents, Surgery, 030220 oncology & carcinogenesis, Breast implant, Female, Patient-reported outcome, Implant, Breast reconstruction, Complication, business, Negative-Pressure Wound Therapy
Abstract

Implant loss due to infection is the most devastating complication of implant-based breast reconstruction. The use of negative pressure wound therapy with instillation(NPWTi) for salvage of infected implant-based breast reconstructions has shown promising results allowing early reinsertion of a new implant as an alternative to the current management with delayed reinsertion. This study compares the patient-reported outcome and cost implication of NPWTi to the current management.Twenty cases of infected breast implants treated with NPWTi(V.A.C. VERAFLO™ Therapy), followed by early reinsertion of new implants were compared to 20 cases that had delayed reinsertion(non-NPWTi). Patient satisfaction was evaluated using the BREAST-Q questionnaire. The average cost per patient was calculated using total operative expense, cost of inpatient stay, investigations, antibiotics, and outpatient visits.Treatment with NPWTi allowed earlier reinsertion of a new implant (NPWTi: 10.3 ± 2.77days vs. non-NPWTi: 247.45±111.28days, p0.001). Patients in the NPWTi group reported higher satisfaction. The average cost per patient for NPWTi and non-NPWTi was £14,343.13±£2,786.70 and £8,920.31±£3,005.73, respectively(p0.001). All patients treated with NPWTi had one admission and spent 11.9 ± 4.1days as inpatients, while non-NPWTi patients had 2.1 ± 0.3 admissions(p0.001) and spent 7.1 ± 5.8days(p0.004) as inpatients. Patients treated with NPWTi had more procedures (NPWTi:3.35±0.81 Vs. non-NPWTi:2.2 ± 0.41, p = 0.006); however, three non-NPWTi cases required flap reconstruction.Patients treated with NPWTi reported higher satisfaction, received a new and earlier implant, and had fewer admissions and outpatient visits; however, they incurred higher average costs, longer inpatient stays, and underwent more procedures. Early implant reinsertion preserves skin envelope; hence avoiding additional cost and stress related to further major autologous reconstruction.

Published
2021
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46. Anxiety sensitivity as a transdiagnostic risk factor for trajectories of adverse posttraumatic neuropsychiatric sequelae in the AURORA study

Author

Short, Nicole A., primary, van Rooij, Sanne J.H., additional, Murty, Vishnu P., additional, Stevens, Jennifer S., additional, An, Xinming, additional, Ji, Yinyao, additional, McLean, Samuel A., additional, House, Stacey L., additional, Beaudoin, Francesca L., additional, Zeng, Donglin, additional, Neylan, Thomas C., additional, Clifford, Gari D., additional, Linnstaedt, Sarah D., additional, Germine, Laura T., additional, Bollen, Kenneth A., additional, Rauch, Scott L., additional, Haran, John P., additional, Lewandowski, Christopher, additional, Musey, Paul I., additional, Hendry, Phyllis L., additional, Sheikh, Sophia, additional, Jones, Christopher W., additional, Punches, Brittany E., additional, Swor, Robert A., additional, McGrath, Meghan E., additional, Hudak, Lauren A., additional, Pascual, Jose L., additional, Seamon, Mark J., additional, Datner, Elizabeth M., additional, Pearson, Claire, additional, Peak, David A., additional, Merchant, Roland C., additional, Domeier, Robert M., additional, Rathlev, Niels K., additional, O'Neil, Brian J., additional, Sergot, Paulina, additional, Sanchez, Leon D., additional, Bruce, Steven E., additional, Pietrzak, Robert H., additional, Joormann, Jutta, additional, Barch, Deanna M., additional, Pizzagalli, Diego A., additional, Sheridan, John F., additional, Smoller, Jordan W., additional, Harte, Steven E., additional, Elliott, James M., additional, Kessler, Ronald C., additional, Koenen, Karestan C., additional, and Jovanovic, Tanja, additional

Published
2022
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48. Efficacy, safety, and immunogenicity of a booster regimen of Ad26.COV2.S vaccine against COVID-19 (ENSEMBLE2): results of a randomised, double-blind, placebo-controlled, phase 3 trial

Author

Hardt, Karin, primary, Vandebosch, An, additional, Sadoff, Jerald, additional, Le Gars, Mathieu, additional, Truyers, Carla, additional, Lowson, David, additional, Van Dromme, Ilse, additional, Vingerhoets, Johan, additional, Kamphuis, Tobias, additional, Scheper, Gert, additional, Ruiz-Guiñazú, Javier, additional, Faust, Saul N, additional, Spinner, Christoph D, additional, Schuitemaker, Hanneke, additional, Van Hoof, Johan, additional, Douoguih, Macaya, additional, Struyf, Frank, additional, Garibaldi, Brian T., additional, Albertson, Timothy E., additional, Sandrock, Christian, additional, Lee, Janet S., additional, Looney, Mark R., additional, Tapson, Victor F., additional, Wiysonge, Charles Shey, additional, Velarde, Luis Humberto Anaya, additional, Backenroth, Daniel, additional, Bhushanan, Jisha, additional, Brandenburg, Börries, additional, Cárdenas, Vicky, additional, Chen, Bohang, additional, Chen, Fei, additional, Chetty, Polan, additional, Chu, Pei-Ling, additional, Cooper, Kimberly, additional, Custers, Jerome, additional, Delanghe, Hilde, additional, Duca, Anna, additional, Henrick, Tracy, additional, Juraszek, Jarek, additional, Nalpas, Catherine, additional, Peeters, Monika, additional, Pinheiro, Jose, additional, Roels, Sanne, additional, Ryser, Martin F., additional, Salas, Jose, additional, Santoro Matias, Samantha, additional, Scheys, Ilse, additional, Shetty, Pallavi, additional, Shukarev, Georgi, additional, Stoddard, Jeffrey, additional, Talloen, Willem, additional, Tran, NamPhuong, additional, Vaissiere, Nathalie, additional, van Son-Palmen, Elisabeth, additional, Xu, Jiajun, additional, Goecker, Erin A., additional, Greninger, Alexander L., additional, Jerome, Keith R., additional, Roychoudhury, Pavitra, additional, Takuva, Simbarashe G., additional, Accini Mendoza, Jose Luis, additional, Achtyes, Eric, additional, Ahsan, Habibul, additional, Alhatemi, Azhar, additional, Allen, Nancy, additional, Arribas, Jose R., additional, Bahrami, Ghazaleh, additional, Bailon, Lucia, additional, Bajwa, Ali, additional, Baker, Jonathan, additional, Baron, Mira, additional, Benet, Susana, additional, Berdaï, Driss, additional, Berger, Patrick, additional, Bertoch, Todd, additional, Bethune, Claire, additional, Bevilacqua, Sybille, additional, Biagioni Santos, Maria Silvia, additional, Binnian, Ian, additional, Bisnauthsing, Karen, additional, Boivin, Jean-Marc, additional, Bollen, Hilde, additional, Bonnet, Sandrine, additional, Borobia, Alberto M., additional, Botelho-Nevers, Elisabeth, additional, Bright, Phil, additional, Britten, Vianne, additional, Brown, Claire, additional, Buadi, Amanda, additional, Buntinx, Erik, additional, Burgess, Lesley, additional, Bush, Larry, additional, Capeding, Maria Rosario, additional, Carr, Quito Osuna, additional, Carrasco Mas, Amparo, additional, Catala, Hélène, additional, Cathie, Katrina, additional, Caudill, T. Shawn, additional, Cereto Castro, Fernando, additional, Chau, Kénora, additional, Chavoustie, Steven, additional, Chowdhury, Marie, additional, Chronos, Nicolas, additional, Cicconi, Paola, additional, Cifuentes, Liliana, additional, Cobo, Sara Maria, additional, Collins, Helen, additional, Colton, Hayley, additional, Cuaño, Carlos Rolando G., additional, D'Onofrio, Valentino, additional, Dargan, Paul, additional, Darton, Thomas, additional, Deane, Peter, additional, Del Pozo, Jose Luis, additional, Derdelinckx, Inge, additional, Desai, Amisha, additional, Dever, Michael, additional, Díaz-Pollán, Beatriz, additional, DiBuono, Mark, additional, Doust, Matthew, additional, Duncan, Christopher, additional, Echave-Sustaeta, Jose Maria, additional, Eder, Frank, additional, Ellis, Kimberly, additional, Elzi, Stanton, additional, Emmett, Stevan, additional, Engelbrecht, Johannes, additional, Evans, Mim, additional, Farah, Theo, additional, Felton, Timothy, additional, Ferreira, João Pedro, additional, Floutier, Catherine, additional, Flume, Patrick, additional, Ford, Stacy, additional, Fragoso, Veronica, additional, Freedman, Andrew, additional, Frentiu, Emilia, additional, Galloway, Christopher, additional, Galtier, Florence, additional, Garcia Diaz, Julia, additional, García García, Irene, additional, Garcia, Alcaide, additional, Gardener, Zoe, additional, Gauteul, Pascale, additional, Geller, Steven, additional, Gibson, Andrew, additional, Gillet, Claudia, additional, Girerd, Nicolas, additional, Girodet, Pierre-Olivier, additional, Gler, Maria Tarcela, additional, Glover, Richard, additional, Go, Herschel Don D., additional, Gokani, Karishma, additional, Gonthier, Damien, additional, Green, Christopher, additional, Greenberg, Richard, additional, Griffin, Carl, additional, Grobbelaar, Coert, additional, Guancia, Adonis, additional, Hakkarainen, Gloria, additional, Harris, James, additional, Hassman, Michael, additional, Heimer, Deirdre, additional, Hellstrom-Louw, Elizabeth, additional, Herades, Yoan, additional, Holroyd, Christopher, additional, Hussen, Nazreen, additional, Isidro, Marie Grace Dawn, additional, Jackson, Yvonne, additional, Jain, Manish, additional, João Filho, Esaú Custódio, additional, Johnson, Daniel, additional, Jones, Ben, additional, Joseph, Natasha, additional, Jumeras, Analyn, additional, Junquera, Patricia, additional, Kellett-Wright, Johanna, additional, Kennedy, Patrick, additional, Kilgore, Paul E., additional, Kim, Kenneth, additional, Kimmel, Murray, additional, Konis, George, additional, Kutner, Mark, additional, Lacombe, Karine, additional, Launay, Odile, additional, Lazarus, Rajeka, additional, Lederman, Samuel, additional, Lefebvre, Gigi, additional, Lennon Collins, Katrina, additional, Leroux-Roels, Isabel, additional, Lim, Kenneth Wilson O., additional, Lins, Muriel, additional, Liu, Edward, additional, Llewelyn, Martin, additional, Mahomed, Akbar, additional, Maia, Bernardo Porto, additional, Marín-Candon, Alícia, additional, Martínez-Gómez, Xavier, additional, Martinot, Jean Benoit, additional, Mazzella, Andrea, additional, McCaughan, Frank, additional, McCormack, Louise, additional, McGettigan, John, additional, Mehra, Purvi, additional, Mejeur, Rhonda, additional, Miller, Vicki, additional, Mills, Anthony, additional, Molto Marhuenda, Jose, additional, Moodley, Prebashan, additional, Mora-Rillo, Marta, additional, Mothe, Beatriz, additional, Mullan, Daniel, additional, Munro, Alasdair, additional, Myers, Paul, additional, Nell, Jeremy, additional, Newman Lobato Souza, Tamara, additional, O'Halloran, Jane A., additional, Ochoa Mazarro, Maria Dolores, additional, Oliver, Abigail, additional, Onate Gutierrez, Jose Millan, additional, Ortega, Jessica, additional, Oshita, Masaru, additional, Otero Romero, Susana, additional, Overcash, Jeffrey Scott, additional, Owens, Daniel, additional, Packham, Alice, additional, Pacurar, Mihaela, additional, Paiva de Sousa, Leonardo, additional, Palfreeman, Adrian, additional, Pallares, Christian José, additional, Patel, Rahul, additional, Patel, Suchet, additional, Pelkey, Leslie, additional, Peluso, Denise, additional, Penciu, Florentina, additional, Pinto, S. Jerry, additional, Pounds, Kevin, additional, Pouzar, Joe, additional, Pragalos, Antoinette, additional, Presti, Rachel, additional, Price, David, additional, Qureshi, Ehsaan, additional, Ramalho Madruga, José Valdez, additional, Ramesh, Mayur, additional, Rankin, Bruce, additional, Razat, Béatrice, additional, Riegel Santos, Breno, additional, Riesenberg, Robert, additional, Riffer, Ernie, additional, Roche, Siobhan, additional, Rose, Katie, additional, Rosellini, Pietro, additional, Rossignol, Patrick, additional, Safirstein, Beth, additional, Salazar, Hernan, additional, Sanchez Vallejo, Gregorio, additional, Santhosh, Smrithi, additional, Seco-Meseguer, Enrique, additional, Seep, Michael, additional, Sherry, Emma, additional, Short, Philip, additional, Soentjens, Patrick, additional, Solis, Joel, additional, Soriano Viladomiu, Alejandro, additional, Sorli, Caroline, additional, Spangenthal, Selwyn, additional, Spence, Niamh, additional, Stephenson, Elaine, additional, Strout, Cynthia, additional, Surowitz, Ronald, additional, Taladua, Kristy Michelle, additional, Tellalian, David, additional, Thalamas, Claire, additional, Thiriphoo, Nang, additional, Thomas, Judith, additional, Thomas, Nicholas, additional, Trout, Guillermo, additional, Urroz, Mikel, additional, Veekmans, Bernard, additional, Veekmans, Laurent, additional, Villalobos, Ralph Elvi M., additional, Warren, Sarah, additional, Webster, Brian, additional, White, Alexander, additional, Williams, Gail, additional, Williams, Hayes, additional, Wilson, Barbara, additional, Winston, Alan, additional, Wiselka, Martin, additional, and Zervos, Marcus, additional

Published
2022
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49. Diagnosis and treatment of pancreatic duct disruption or disconnection: an international expert survey and case vignette study

Author

S. Rana, M. Barthet, C. Fernandez-del Castillo, J. French, Karen D. Horvath, J. E. van Hooft, Christos Dervenis, M. Pelaez-Luna, H. van Goor, M.W. Büchler, Matthias Löhr, S. Connor, K. Lillemoe, V. Nieuwenhuijs, John A. Windsor, E. Bradley, W. Traverso, C.H.J. van Eijck, Shuiji Isaji, C. Dejong, Ajith K. Siriwardena, Martin L. Freeman, M. Jagielski, S. Moon, Richard Charnley, R. Timmer, Marianna Arvanitakis, Marja A. Boermeester, Rogier P. Voermans, H. Karjula, Chris E. Forsmark, Julia Mayerle, P. Fagenholz, Vijay P. Singh, Jacques Devière, A. Badaoui, A. Mittal, Vincent C. Cappendijk, Paul Fockens, Marc G. Besselink, Hjalmar C. van Santvoort, P. Dellinger, Stuart Sherman, N. Zyromski, M. Stommel, Jörg G. Albert, Jean-Marc Dumonceau, D. Morgan, F. Téllez-Avina, Hester C. Timmerhuis, Thomas L. Bollen, Vinciane Rebours, M. Tann, J.W. Poley, S. Seewald, Phillippe Levy, T. Hucl, B. Joseph Elmunzer, D. Radenkovic, Marco J. Bruno, J.W. Haveman, Lotte Boxhoorn, Robert C. Verdonk, A. Zaheer, Markus M. Lerch, Michael G. Sarr, G. van Biervliet, Graduate School, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Gastroenterology and Hepatology, Surgery, APH - Methodology, and Gastroenterology & Hepatology

Subjects
medicine.medical_specialty, Percutaneous, education, Amylase levels, MEDLINE, Case vignette, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Pancreatic duct, Response rate (survey), Hepatology, Pancreatitis, Acute Necrotizing, business.industry, General surgery, Pancreatic Ducts, Gastroenterology, medicine.disease, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Acute Disease, Drainage, Acute pancreatitis, 030211 gastroenterology & hepatology, Disconnection, business
Abstract

Contains fulltext : 238998.pdf (Publisher’s version ) (Open Access) BACKGROUND: Pancreatic duct disruption or disconnection is a potentially severe complication of necrotizing pancreatitis. With no existing treatment guidelines, it is unclear whether there is any consensus among experts in clinical practice. We evaluated current expert opinion regarding the diagnosis and treatment of pancreatic duct disruption and disconnection in an international case vignette study. METHODS: An online case vignette survey was sent to 110 international expert pancreatologists. Expert selection was based on publications in the last 5 years and/or participation in development of IAP/APA and ESGE guidelines on acute pancreatitis. Consensus was defined as agreement by at least 75% of the experts. RESULTS: The response rate was 51% (n = 56). Forty-four experts (79%) obtained a MRI/MRCP and 52 experts (93%) measured amylase levels in percutaneous drain fluid to evaluate pancreatic duct integrity. The majority of experts favored endoscopic transluminal drainage for infected (peri)pancreatic necrosis and pancreatic duct disruption (84%, n = 45) or disconnection (88%, n = 43). Consensus was lacking regarding the treatment of patients with persistent percutaneous drain production, and with persistent sterile necrosis. CONCLUSION: This international survey of experts demonstrates that there are many areas for which no consensus existed, providing clear focus for future investigation.

Published
2021
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50. Potential Renoprotective Strategies in Adult Cardiac Surgery: A Survey of Society of Cardiovascular Anesthesiologists Members to Explore the Rationale and Beliefs Driving Current Clinical Decision-Making

Author

Alexander Zarbock, Bennett Roman, Amanda A. Fox, Bruce A. Bollen, Linda Shore-Lesserson, Hong Liu, Frederic T. Billings, David R. McIlroy, Mariya Geube, and Andrew D. Shaw

Subjects
medicine.medical_specialty, business.industry, Psychological intervention, Acute kidney injury, Renal function, Perioperative, Affect (psychology), medicine.disease, Cardiac surgery, Anesthesiology and Pain Medicine, Blood pressure, Cardiothoracic surgery, medicine, Cardiology and Cardiovascular Medicine, Intensive care medicine, business
Abstract

Objectives The authors sought to (1) characterize the rationale underpinning anesthesiologists’ use of various perioperative strategies hypothesized to affect renal function in adult patients undergoing cardiac surgery, (2) characterize existing belief about the quality of evidence addressing the renal impact of these strategies, and (3) identify potentially renoprotective strategies for which anesthesiologists would most value a detailed, evidence-based review. Design Survey of perioperative practice in adult patients undergoing cardiac surgery. Setting Online survey. Participants Members of the Society of Cardiovascular Anesthesiologists (SCA). Interventions None. Measurements & Main Results The survey was distributed to more than 2,000 SCA members and completed in whole or in part by 202 respondents. Selection of target intraoperative blood pressure (and relative hypotension avoidance) was the strategy most frequently reported to reflect belief about its potential renal effect (79%; 95% CI: 72-85). Most respondents believed the evidence supporting an effect on renal injury of intraoperative target blood pressure during cardiac surgery was of high or moderate quality. Other factors, including a specific nonrenal rationale, surgeon preference, department- or institution-level decisions, tradition, or habit, also frequently were reported to affect decision making across queried strategies. Potential renoprotective strategies most frequently requested for inclusion in a subsequent detailed, evidence-based review were intraoperative target blood pressure and choice of vasopressor agent to achieve target pressure. Conclusions A large number of perioperative strategies are believed to variably affect renal injury in adult patients undergoing cardiac surgery, with wide variation in perceived quality of evidence for a renal effect of these strategies.

Published
2021
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