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The accelerated mix modelling approach is a powerful tool for producing high-performance characteristics in young concrete. Since rapid concrete curing accelerates the cement hydration process, the critical portion of the strength is achieved in a fraction of the time it would usually require 28 days under conventional curing conditions. There is no suggestion that Ground Granulated Blast Furnace slag, Silica fume or fly ash was used in the 1980 s . So far, only plain concrete has a connection in the accelerated mix design process. The accelerated curing method was used in this study with a combination of GGBS, fly ash, and silica fume, as well as two different water-binder ratios of 0.3 and 0.4, and by applying 5% silica fume to cement weight, concentrations of GGBS and fly ash as high as 70%, 60% and 50% can be achieved. Normal laboratory size cubes (150 x150 x150mm) were compressed and tested to achieve the goals of this analysis. Compressive strength, impact of GGBS rate and impact of water-concrete proportion were used to improve the consistency of blended concrete with accelerated curing method. This analysis will determine correlations between the boiling water strength and for 28 days, 56 days and 90 days strength of concrete with GGBS, fly ash and Silica fume.

Blended cement containing natural zeolite powder exhibits improved performance & resistance to concrete against aggressive environmental attacks. Concrete structures when exposed to aggressive environments possess several negative impacts due to migration of chloride & sulphate ions, carbonation, acid attack, etc. Due to these, exposures the concrete structure lose their strength gradually, which results in the decreased life span. At present, research work focused on the influence of lower w/b ratios on higher replacement levels of zeolite on the performance of concrete in mechanical & durability aspects. And this study also attempts to generate quantitative data & understand the relationship between lower water-binder ratios 0.30 & 0.40 and higher replacement levels 30%, 40% of zeolite & compressive strength. Mechanical aspects such as compressive strength, split tensile strength, flexural strength tests. Durability aspects like chloride attack through Rapid chloride penetration test (RCPT), Sulphuric acid attack. Magnesium sulphate attack, tests were carried out. Altogether, in the practical point of view test results revealed that concrete incorporating natural zeolite powder gets substantial compressive strength beyond the 28-day period, i.e., strength increases gradually with respect to time. Improvement is noticed at a low water-binder ratio. Increases resistance against chloride, sulphate attacks.

Generally, the life of R.C structure is expected to be 100 years, but today’s structures are failing in 30 years due to corrosion of reinforced steel. One of the major problem to concrete from environmental attack is chloride ingress which leads to corrosion of reinforcement bars further leads to decrease of its strength and service life of structure. The focus of the work is on the chloride ion concentration at different depth in non-steady diffusion. Nine concrete mixes with different percentages of supplementary cementitious materials and water to cementitious ratios of 0.3, 0.4, & 0.5 were casted and compared with convention mixes (without replacing cement). The replacing of cement with different percentages of 30%, 50% & 70% and with 5% silica fume. Strength of concrete tested for 28, 56 & 90 days. Specimens were conducted ponding test for 6 & 12 weeks of 3.5% NaCl solution. Chemical analysis is carried out for predicting chloride concentration in concrete at different depths from surface exposed NaCl specimens.

Different doses of ethanolic fraction of fruits of Terminalia pallida were evaluated for hypoglycemic and antihyperglycemic activity in normal and alloxan diabetic rats. The oral administration of ethanolic extract at a dosage of 0.5 g/kg body weight exhibited a significant antihyperglycemic activity in alloxan diabetic rats, whereas in normal rats no hypoglycemic activity was observed.

Aqueous, ethanolic and hexane fractions of Momordica cymbalaria fruits were prepared and given individually at different doses to different batches of rats (both normal and alloxan diabetic rats) after an overnight fast. The blood glucose levels were measured at 0, 1, 3, 5 and 7 h after the treatment. The aqueous extract of Momordica cymbalaria at a dosage of 0.5 g/kg b.w. is showing maximal blood glucose lowering effect in diabetic rats. The same dosage did not produce any hypoglycemic activity in normal rats. The antihyperglycemic activity of Momordica cymbalaria fruit was compared with the treatment of Glibenclamide, an oral hypoglycemic agent.

Lipid peroxides are thought to be formed by free radicals and may play an important role in the development of atheromatous vascular diseases. The relationship between serum lipids, lipoproteins, lipid peroxides [thiobarbituric acid reactive substances (TBARS)] and erythrocyte antioxidant enzymes [catalase (CAT), glutathione peroxidase (GPx) and superoxide dismutase (SOD)] was investigated in non-insulin-dependent diabetic patients with and without coronary heart disease (CHD), and a comparison was made for all the above parameters with non-diabetic patients with CHD. Lipid peroxide concentrations were significantly increased in both groups of diabetic patients and also in non-diabetic patients with CHD, compared to those in control subjects. Diabetic patients with CHD had higher levels of TBARS compared to those diabetics without CHD. Hyperlipidaemia and abnormal lipoprotein levels were observed in all three groups of patients. Increased total cholesterol and LDL-cholesterol were observed in diabetics with CHD compared to those without CHD. Among the erythrocyte antioxidant enzymes, CAT activity was increased, GPx activity was decreased and no change was observed in SOD activity in both groups of diabetic patients and non-diabetic patients with CHD compared to those in controls. A clear correlation was observed between the CAT activity and lipid peroxide concentrations in all the diabetic patients. These observations suggest that there are similar abnormalities in lipid metabolism and erythrocyte antioxidant enzymes in diabetic patients and non-diabetic patients with CHD.

Summary Aqueous, ethanolic and hexane fractions of Syzygium alternifolium seeds were prepared and given different doses of these extracts individually to different batches of rats (both normal and alloxan diabetic rats) after an overnight fast. The blood glucose levels were measured at 0, 1, 3, 5 and 7 hours after the treatment. The aqueous extract of Syzygium alternifolium at a dosage of 0.75 g/kg b.w. is showing maximum blood glucose lowering effect in both normal and alloxan diabetic rats. The ethanol and hexane fractions are also showing hypoglycemic and antihyperglycemic activity, but the effect is significantly less than that of aqueous extract. The antihyperglycemic activity of Syzygium alternifolium seed was compared with the treatment of Glibenclamide.

The effect of administration of different doses of Pterocarpus santalinus L. bark extracts in normal and diabetic rats, on blood glucose levels was evaluated in this study. Among the three fractions (aqueous, ethanol and hexane), ethanolic fraction at the dose of 0.25 g/kg body weight showed maximum antihyperglycemic activity. The same dose did not cause any hypoglycemic activity in normal rats. The results were compared with the diabetic rats treated with glibenclamide and the antihyperglycemic activity of ethanolic extract of PS bark at the dose of 0.25 g/kg b.w. was found to be more effective than that of glibenclamide.