11 results on '"Ashley Wong"'
Search Results
2. Modified Frailty Index Does Not Provide Additional Value in Predicting Outcomes in Patients Undergoing Elective Transforaminal Lumbar Interbody Fusion
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Khoa S. Tran, Mark J. Lambrechts, Tariq Z. Issa, Eric Tecce, Andrew Corr, Gregory R. Toci, Ashley Wong, Stephen DiMaria, Quinn Kirkpatrick, Justin Chu, Griffin Gilmore, Mark F. Kurd, Jeffery A. Rihn, Barrett I. Woods, Ian David Kaye, Jose A. Canseco, Alan S. Hilibrand, Christopher K. Kepler, Alexander R. Vaccaro, and Gregory D. Schroeder
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Surgery ,Neurology (clinical) - Abstract
To determine the predictive value of the modified Frailty Index (mFI) in evaluating sarcopenia and clinical outcomes in patients undergoing 1-level or 2-level transforaminal lumbar interbody fusion (TLIF).Patients who underwent a 1-level or 2-level TLIF between 2012 and 2020 were retrospectively identified. Frailty was compared among groups using mFI, and sarcopenia was classified by the psoas muscle cross-sectional area. Bivariate statistics compared demographics, comorbidities, and clinical outcomes. A linear regression model was developed using the Charlson Comorbidity Index (CCI) or mFI as independent variables to determine potential predictors for improvement in 1-year patient-reported outcomes.Of 488 included patients, 60 were severely frail and 60 patients had sarcopenia, but sarcopenia was not associated with patient frailty (P = 0.469). Severely frail patients had worse baseline Oswestry Disability Index (ODI) (P0.001), Mental Component Score-12 (P = 0.001), and Physical Component Score-12 (P0.001), and worse improvement in ODI (P = 0.037), Physical Component Score-12 (P0.001), and visual analog scale (VAS) back (P = 0.007). mFI was an independent predictor of poorer improvement in VAS back and ODI, whereas age + CCI in addition predicted poorer improvement in VAS leg. Patients with higher mFI experienced longer length of stay, less frequent home discharge, and higher rates of complications, but similar readmission and reoperation rates.Frailer patients experience poorer improvement in back pain, physical functioning, and disability after TLIF. mFI and the combination of age and CCI comparably predict patient-reported outcomes but do not correlate to baseline sarcopenia. Frailty increased the risk of complications, length of hospital stay, and risk of nonhome discharge.
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- 2023
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3. P354: An apparently new brain MRI finding in Sotos syndrome: Extensively dilated perivascular spaces
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Leah Wibecan, Angela Lin, Karen Buch, Otto Rapalino, Frances High, Ashley Wong, Dorit Koren, G. Bradley Schaefer, and Danielle Pier
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- 2023
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4. Impact of the COVID-19 pandemic on sports and exercise
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Samuel K.K. Ling, Lobo H T Louie, Daniel Chi Wo Lee, George Ying Kan Law, Raymond Chi Hung So, Patrick Shu-Hang Yung, Ashley Wong, and Forrest Chung Fai Yau
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medicine.medical_specialty ,Sports medicine ,Physical Therapy, Sports Therapy and Rehabilitation ,Football ,Sports Medicine ,Article ,03 medical and health sciences ,0302 clinical medicine ,Deconditioning ,Heart rate ,medicine ,Orthopedics and Sports Medicine ,lcsh:Sports medicine ,Exercise ,Balance (ability) ,030222 orthopedics ,Pandemic ,business.industry ,Social distance ,Risk of infection ,Rehabilitation ,Immunity ,COVID-19 ,Repeated measures design ,030229 sport sciences ,Physical therapy ,Infection ,lcsh:RC1200-1245 ,business ,human activities - Abstract
COVID-19 is a droplet-transmitted potentially fatal coronavirus pandemic affecting the world in 2020. The WHO recommended social distancing and human-to-human contact was discouraged to control the transmission. It has put many countries in a state of lockdown and sporting events (including the 2020 Olympics) have been affected. Participation in sports and exercise, typically regarded as healthy activities, were also debated. The local professional football leagues, governed by the Hong Kong Football Association, ultimately postponed all matches after much deliberation on the transmission risk for the spectators and on-field players. Large spectating crowds are well-known to be infectious hazards, but the infection risk for on-field players is less recognized. To address this question, we performed a small-scale investigation that showed, in a 90 min match, the average duration of close contact between players was 19 min and each player performed an average of 52 episodes of infection-risky behaviours. This suggests that the infection risk was high for the players, even without spectators. Aside from watching professionals exercise, many people opted to hike in the countryside during the weekends to avoid city crowds. This led to a widespread discussion on the issue of masked versus unmasked hiking. We performed a laboratory study to investigate the physiological effect of wearing a facemask during simulated hiking and found that it significantly elevated heart rate and perceived exertion. The clinical implication is that hikers need to realize masks increase the physiological burden, especially in those with multiple underlying comorbidities. Elite athletes, especially those training for the upcoming Olympics, needed to balance and reschedule their training regime since the risk of deconditioning versus the risk of infection was a genuine dilemma for themselves and their team. We described the multiple infection-control measures imposed by the national team training centre to help strike this balance. Amidst a global pandemic affecting millions; staying active is good, but staying safe is paramount., Highlights • Staying active during a pandemic like COVID-19 requires smart tactics. • As the team physicians, we described the strategies utilised to balance infection control and sports during COVID-19 in the professional football league and the Olympic team's training. • Contact sports like football, even without spectating crowds, pose an infection risk to the players; while exercising with face-masks cases a significant increase in physiological demand.
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- 2020
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5. Catalytic aromatization of naphtha under methane environment: Effect of surface acidity and metal modification of HZSM-5
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Jack Jarvis, Peng He, Ashley Wong, Qingyin Li, and Hua Song
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010405 organic chemistry ,Chemistry ,020209 energy ,General Chemical Engineering ,Organic Chemistry ,Aromatization ,Energy Engineering and Power Technology ,02 engineering and technology ,Heterogeneous catalysis ,01 natural sciences ,Methane ,0104 chemical sciences ,Catalysis ,chemistry.chemical_compound ,Fuel Technology ,Chemical engineering ,0202 electrical engineering, electronic engineering, information engineering ,Lewis acids and bases ,Selectivity ,Naphtha ,Bimetallic strip - Abstract
The reformation of naphtha to obtain valuable chemical intermediates such as BTX has attracted much attention. Here we report a novel catalytic process whereby a bimetallic heterogeneous catalyst in the form of Zn-Pt/HZSM-5 is applied to a flow reactor system to reform a complex naphtha feed under a methane environment. Different levels of acidity of the HZSM-5 support are tested with a superior performance witnessed using a SiO2:Al2O3 ratio at 80. Further testing is conducted using Zn as a dehydrogenating component with improved performance witnessed when Zn is loaded to a certain degree. A metal promoter is then combined with Zn to compare the effect of different promoters with superior performance witnessed using Ga and Pt as promoters with Zn. BTX selectivity and BTX yield are reported as 86.44% and 34.22% respectively under the Zn-Pt/HZSM-5 catalyst. External site coverage improves performance for all bimetallic catalysts with the exception of Zn-Pt/HZSM-5, suggesting that Pt might not promote the migration of metal functions to the internal pores during synthesis. XRD spectra demonstrate that Pt addition results in a more intact crystal structure after reaction when compared to Zn alone·NH3-TPD and DRIFT analyses show a reduced amount of strong acidic sites upon metal loading with an increase in the number of Lewis acid sites and reduced Bronsted sites. This change in acidity could be one of the reasons for an improved performance when Zn-Pt/HZSM-5 is employed. The effect of methane is also witnessed over Zn-Pt/HZSM-5 with improved selectivity, yield (BTX and liquid) and active metal dispersion when compared to a nitrogen environment, suggesting the possible incorporation of methane into the products, BTX in particular. Ultimately, the catalyst employed here opens an avenue for further research into the possible industrial application of naphtha aromatization to form valuable chemical products under methane environment.
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- 2018
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6. Parental motivations for seeking second medical opinions for their child’s HPV vaccine
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Katherine E. Spanos, William A. Calo, Benjamin Fogel, Jennifer L. Kraschnewski, and Ashley Wong
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Young child ,business.industry ,Short Communication ,Public Health, Environmental and Occupational Health ,Hpv vaccination ,Health Informatics ,Odds ratio ,Vaccine refusal ,Logistic regression ,Confidence interval ,Vaccine communication ,Medicine ,Social media ,Second opinion ,Human papillomavirus ,business ,HPV vaccine ,Demography - Abstract
We sought to characterize parents who look for second medical opinions to get human papillomavirus (HPV) vaccine for their children and whether second opinions influenced acceptance of HPV vaccine. Between July and August 2019, we conducted an online survey with a national sample of 906 parents of adolescents ages 11–17. We used multivariable logistic regression to assess correlates of looking for second opinions on HPV vaccination. For those who looked for second opinions, the survey assessed their HPV vaccine information needs and whether their child ultimately received the vaccine. Overall, 15% of parents reported looking for second opinions. Parents were more likely to look for second opinions if their self-reported knowledge about HPV vaccine was the same (Odds ratio [OR] = 1.94; 95% confidence interval [CI]:1.13, 3.30) or more (OR = 3.97; 95% CI:2.35, 6.73) than their child’s provider, or if they reported seeing HPV vaccine information on social media (OR = 2.50; 95% CI:1.69, 3.69). Parents were also more likely to look for second opinions if they were male, reported low vaccine confidence, disagreed with social norms favoring HPV vaccination, or had a young child (all p
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- 2021
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7. 925: Antenatal maternal hypoglycemia is associated with adverse neonatal outcomes in women with gestational diabetes
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Anna Palatnik, Meredith Cruz, Ashley Wong, Rachel Harrison, and Caroline C. Davitt
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Gestational diabetes ,medicine.medical_specialty ,Obstetrics ,Neonatal outcomes ,business.industry ,medicine ,Obstetrics and Gynecology ,Hypoglycemia ,medicine.disease ,business - Published
- 2020
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8. 1041: The association between provider and glycemic threshold for pharmacotherapy initiation for treatment of Gestational Diabetes
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Alyssa Stiff, Caroline C. Davitt, Rachel Harrison, Anna Palatnik, Meredith Cruz, and Ashley Wong
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Gestational diabetes ,medicine.medical_specialty ,business.industry ,Internal medicine ,medicine ,Obstetrics and Gynecology ,medicine.disease ,business ,Pharmacotherapy Initiation ,Glycemic - Published
- 2020
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9. Intergenerational Health Mobility in the US
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Timothy Halliday, Bhashkar Mazumder, and Ashley Wong
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- 2018
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10. Comparing transabdominal and transvaginal ultrasound-guided follicular aspiration: A risk assessment formula
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Caleb J. Siefert, Linda Sung, Ashley Wong, Ellerie S. Weissbrot, Chaur-Dong Hsu, and Christian F. Roman-Rodriguez
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Adult ,medicine.medical_specialty ,medicine.medical_treatment ,lcsh:Gynecology and obstetrics ,Risk Assessment ,Sensitivity and Specificity ,Body Mass Index ,in vitro fertilization ,oocyte retrieval ,Ovarian Follicle ,Predictive Value of Tests ,Obstetrics and Gynaecology ,medicine ,Humans ,lcsh:RG1-991 ,Ultrasonography, Interventional ,Retrospective Studies ,Gynecology ,Pregnancy ,In vitro fertilisation ,Transvaginal oocyte retrieval ,Obstetrics ,business.industry ,transvaginal follicular aspiration ,Obstetrics and Gynecology ,Abdominal Cavity ,Retrospective cohort study ,medicine.disease ,ovarian displacement ,medicine.anatomical_structure ,Case-Control Studies ,Predictive value of tests ,Vagina ,Female ,transabdominal oocyte retrieval ,Complication ,Risk assessment ,business - Abstract
Objective We sought to identify patients at risk of incomplete transvaginal oocyte retrieval, develop a risk assessment formula to identify patients who would benefit from a transabdominal approach, and compare complication and pregnancy rates between these two approaches. Materials and Methods In this retrospective case control study in a private in vitro fertilization center, 95 cases of women undergoing transabdominal follicular aspiration for oocyte retrieval (15 transabdominal only and 80 transabdominal and vaginal combined) were compared with 278 controls of women undergoing the transvaginal aspiration only. Transabdominal oocyte retrieval was performed when one or more ovaries could not be retrieved via the transvaginal approach. Main study outcomes included need for transabdominal retrieval, pregnancy rates, and complications. Results A risk assessment scoring system was developed as follows: difficulty seeing ovaries on ultrasound (+4), history of pelvic surgery (+3), and body mass index of 30 kg/m 2 or greater (+2). With a cutoff score of 4 or greater, the overall sensitivity is 75%, specificity is 80%, positive predictive value is 57%, and negative predictive value is 90%. No statistically significant differences were found for pregnancy rates or complications. Conclusion The transabdominal approach is an alternative option that would increase the total number of oocytes retrieved with no statistical difference in complication or pregnancy rates. We also developed a scoring system that can serve as a useful screening tool for identifying women at increased risk of transabdominal oocyte retrieval.
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- 2015
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11. Intrafollicular antimüllerian hormone levels predict follicle responsiveness to follicle-stimulating hormone (FSH) in normoandrogenic ovulatory women undergoing gonadotropin releasing-hormone analog/recombinant human FSH therapy for in vitro fertilization and embryo transfer
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Timothy G. Lesnick, Ashley Wong, Daniel A. Dumesic, David H. Abbott, G. David Ball, and Jacques P. Stassart
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endocrine system ,medicine.medical_specialty ,In vitro fertilisation ,urogenital system ,business.industry ,medicine.drug_class ,medicine.medical_treatment ,Obstetrics and Gynecology ,Androgen ,female genital diseases and pregnancy complications ,Embryo transfer ,Andrology ,Follicle-stimulating hormone ,Follicle ,Endocrinology ,Reproductive Medicine ,Private practice ,Dihydrotestosterone ,Internal medicine ,medicine ,business ,hormones, hormone substitutes, and hormone antagonists ,Testosterone ,medicine.drug - Abstract
Objective To investigate the relationship between antimullerian hormone (AMH) and steroidogenesis in follicles of normoandrogenic ovulatory women undergoing follicle-stimulating hormone (FSH) therapy for in vitro fertilization/embryo transfer (IVF-ET). Design Prospective cohort. Setting Institutional/private practice. Patient(s) 26 normoandrogenic ovulatory women. All women received gonadotropin-releasing hormone (GnRH) analog and ovarian stimulation for IVF-ET. Intervention(s) Follicle fluid was aspirated at oocyte retrieval from the first follicle of each ovary. Main Outcome Measure(s) Follicle fluid was assayed for AMH, estradiol (E 2 ), progesterone, androstenedione, testosterone, dihydrotestosterone, insulin, and FSH. Result(s) Intrafollicular AMH levels positively and negatively correlated with E 2 and FSH concentrations in follicles, respectively, causing a positive relationship between follicle fluid AMH levels and E 2 /FSH ratios as a measure of follicle sensitivity to FSH. A positive relationship also existed in follicles between AMH levels and E 2 /androgen ratios as a marker of aromatase activity. Conclusion(s) The AMH levels in follicles of IVF patients positively correlate with follicle sensitivity to FSH.
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- 2009
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