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Telehealth facilitates access to cancer care for patients unable to attend in-person consultations, as in COVID-19. This systematic review used the reach, effectiveness, adoption, implementation, and maintenance (RE-AIM) framework to evaluate telehealth implementation and examine enablers and barriers to optimal implementation in oncology. MEDLINE, PubMed, CINAHL, and the Cochrane Database of Systematic Reviews were searched between January 2011-June 2022. Eighty-two articles representing 73 studies were included. One study explicitly used the RE-AIM framework to guide study design, conduct, or reporting. Reach (44%) and implementation (38%) were most commonly reported, maintenance (5%) least commonly. Key telehealth implementation enablers included professional-led delivery, patient-centred approaches, and positive patient perceptions. Key barriers included patient discomfort with technology, limited supporting clinic infrastructure, and poor access to reliable internet connection and videoconferencing. While a patient-centred and professional-supported approach enables telehealth implementation, technology and infrastructure constraints need surmounting for sustained implementation beyond the COVID-19 pandemic.

Background The process of successful quitting, and the personal and social conditions required to support it, remain poorly understood. Methods This qualitative grounded theory study used in-depth interviews with 37 Australian adult ex-smokers (24–68 years; 15 men and 22 women) who quit in the past 6–24 months to explore how ex-smokers explain their quitting success. Findings This analysis provides a framework for understanding the personal, social and structural factors critical to successful quitting. The key analytic finding was the core concept ‘being serious’. Three factors contributed to ‘being serious’: (1) prior experiences of quitting; (2) an identity (or existential) threat; and (3) timing and circumstances. The analysis indicated that the concept ‘being serious’ rather than the oft-cited psychological constructs motivation and willpower more accurately captures how participants talked about and explained their quitting success, how they accounted for their success when previous apparently similar attempts had failed, and the advice they would offer would-be quitters about achieving quitting success. An explanation is provided for why some participants battled with quitting for years, while others quit unexpectedly, even effortlessly. The social and structural factors that made the state of ‘being serious’ easier or harder for the participant to attain are also discussed. Conclusion ‘Being serious’ was a term that resonated with participants. Participants’ accounts of quitting indicate that quitting is a complex and gradual process and that social and structural influences have a key role in determining how easy or difficult it was to become serious about quitting.

Biofuels are being embraced worldwide as sustainable alternatives to fossil fuels, because of their potential to promote energy security and reduce greenhouse gas emissions, while providing opportunities for job creation and economic diversification. However, biofuel production also raises a number of environmental concerns. One of these is the risk of biological invasion, which is a key issue with second generation biofuel crops derived from fast-growing perennial grasses and woody plant species. Many of the most popular second generation crops proposed for cultivation in the U.S. and Canada are not native to North America, and some are known to be invasive. The development of a large-scale biofuel industry on the continent could lead to the widespread introduction, establishment, and spread of invasive plant species if invasive risks are not properly considered as part of biofuel policy. In this paper, we evaluate the risk of biological invasion posed by the emerging second generation biofuel industry in the U.S. and Canada by examining the invasive risk of candidate biofuel plant species, and reviewing existing biofuel policies to determine how well they address the issue of invasive species. We find that numerous potentially invasive plant species are being considered for biofuel production in the U.S. and Canada, yet invasive risk receives little to no attention in these countries' biofuel policies. We identify several barriers to integrating invasive species and biofuel policy, relating to policy analytical capacity, governance, and conflicting policy objectives. We recommend that governments act now, while the second generation biofuel industry is in its infancy, to develop robust and proactive policy addressing invasive risk. Policy options to minimize biological invasions include banning the use of known invasive plant species, ongoing monitoring of approved species, and use of buffer zones around cultivated areas.

Assisted migration was proposed several decades ago as a means of addressing the impacts of climate change on species populations. While its risks and benefits have been debated, and suggestions for planning and management given, there is little consensus within the academic literature over whether to adopt it as a policy. We evaluated the main features of the assisted migration literature including the study methods, taxonomic groups, geographic regions and disciplines involved. We further assessed the debate about the use of assisted migration, the main barriers to consensus, and the range of recommendations put forth in the literature for policy, planning or implementation. Commentaries and secondary literature reviews were as prevalent as first-hand scientific research and attention focussed on a global rather than regional level. There was little evidence of knowledge transfer outside of the natural sciences, despite the obvious policy relevance. Scholarly debate on this topic has intensified during the last 3 years. We present a conceptual framework for evaluating arguments in the debate, distinguishing among the direct risks and benefits to species, ecosystems and society on the one hand, and other arguments regarding scientific justification, evidence-base and feasibility on the other. We also identify recommendations with potential to advance the debate, including careful evaluation of risks, benefits and trade-offs, involvement of relevant stakeholders and consideration of the complementarity among assisted migration and less risk-tolerant strategies. We conclude, however, that none of these will solve the fundamental, often values-based, challenges in the debate. Solutions are likely to be complex, context-dependent and multi-faceted, emerging from further research, discussion and experience.

Factors shaping population differentiation in low latitude seabirds are not well-understood. In this study, we examined global patterns of DNA sequence variation in the mitochondrial control region of the band-rumped storm-petrel (Oceanodroma castro), a highly pelagic seabird distributed across the sub-tropical and tropical Atlantic and Pacific Oceans. Despite previous classification as a single, monotypic species, fixed haplotype differences occurred between Atlantic and Pacific populations, and among all Pacific populations. In addition, Cape Verde and Galapagos birds formed distinct clades, estimated to have diverged from all other populations at least 150,000 years ago. Azores hot season populations were also genetically distinct, lending support to previous phenotypic evidence that they be recognized as a separate species. Seasonal populations in Madeira probably represent separate genetic management units. The phylogeography of the band-rumped storm-petrel appears to have been shaped by both nonphysical barriers to gene flow and Pleistocene oceanographic conditions. Ancestral populations likely expanded through contiguous range expansion and infrequent long-distance colonization into their current breeding range. These findings suggest several possible revisions to the taxonomy of the band-rumped storm-petrel.

Pullulans produced from the Aureobasidium pullulans fermentation of various agro-industrial wastes were characterised in terms of carbohydrate analysis. heterogeneity and molecular weights. Grape skin pulp extract (GSPE), starch waste (SW), olive oil waste effluents (OW) and molasses (M) were used as substrates for the production of pullulan. A glucose based defined medium (D) was used for comparison purposes. Weight average molecular weights were determined using size exclusion chromatography/multiangle laser light scattering. In each of the ethanol precipitated substances the molecular weights were higher than that of the reference pullulan (Sigma), and the elution profiles indicated the polydisperse nature of the pullulans. When using D, the molecular weight of pullulan produced decreased with increasing fermentation time. Different substrates produced pullulans with different molecular weights. Of the substrates studied, D, GSPE and SW produced pullulans in high yields, which were relatively homogeneous, while OW alone or with M produced greatly heterogeneous ethanol agglutinating substances.