1. Cutaneous malakoplakia: A report of two cases with the use of anti-BCG for the detection for micro-organisms
- Author
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Darius R. Mehregan, Amir H. Mehregan, and David A. Mehregan
- Subjects
Male ,Pathology ,medicine.medical_specialty ,medicine.drug_class ,Dermatology ,Malacoplakia ,Groin ,Monoclonal antibody ,medicine ,Humans ,Tuberculosis, Cutaneous ,Aged ,Skin ,Inclusion Bodies ,Mycobacterium bovis ,biology ,Malakoplakia ,Histiocytes ,biology.organism_classification ,medicine.disease ,Antibodies, Bacterial ,Basophilic ,Infectious disease (medical specialty) ,Polyclonal antibodies ,Axilla ,biology.protein ,Immunostaining - Abstract
Malakoplakia is an uncommon granulomatous infectious disease that is found primarily in the genito-urinary tract, but may rarely involve the skin. Histologic findings are marked by the presence of foamy macrophages containing basophilic concentric spherules, the Michaelis-Gutman bodies. Micro-organisms are not readily identifiable. Immunostaining with polyclonal anti-mycobacterium bovis (BCG) has been described as a method of identifying bacterial and fungal organisms in situations where organisms may be sparse. We report 2 cases of cutaneous malakoplakia with demonstration of organisms by immunostaining with anti-BCG antibodies. (J Am Acad Dermatol 2000;43:351-4.)
- Published
- 2000